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Depression

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 42 articles: HTML format

Single Articles

June 2026
1. BARKO KN, Shelton MA, Kropp DR, Pham TQ, et al
   Impact of sex chromosomes and gonad type in stress susceptibility in corticostriatal brain regions.
   Proc Natl Acad Sci U S A. 2026;123:e2531920123.
   PubMed     Abstract available
   
   
   May 2026
2. VITTALA A, Wu L, Yan D, Liebers D, et al
   Decisional reference point pathology: A cognitive mechanism for and a correlate of major depressive disorder in humans.
   Proc Natl Acad Sci U S A. 2026;123:e2518826123.
   PubMed     Abstract available
   
   
   
3. MADEIRA MM, Hage Z, Koliatsis D, Kokkosis AG, et al
   Pde4 mediates MHCII expression in oligodendroglia.
   Proc Natl Acad Sci U S A. 2026;123:e2511231123.
   PubMed     Abstract available
   
   
   
4. SARNA N, Dar R, Mazor M
   Biased and inattentive responding contribute to apparent metacognitive biases in mental health.
   Proc Natl Acad Sci U S A. 2026;123:e2520832123.
   PubMed     Abstract available
   
   
   
5. MALINOW R
   How ketamine works: An actionable hypothesis.
   Proc Natl Acad Sci U S A. 2026;123:e2533728123.
   PubMed     Abstract available
   
   
   March 2026
6. PANG C, Sun X, Zhao J, Liang X, et al
   Personalized functional topography-based multisite brain age prediction modeling reveals divergent neurodevelopment in major depression.
   Proc Natl Acad Sci U S A. 2026;123:e2519586123.
   PubMed     Abstract available
   
   
   February 2026
7. MAHMOOD N, Dang CL, Wu PY, Huang Z, et al
   The ISR downstream effector ATF4 promotes mGluR-dependent long-term depression and associated behavior.
   Proc Natl Acad Sci U S A. 2026;123:e2532796123.
   PubMed     Abstract available
   
   
   
8. HU Y, Gruen JR, Zhang H
   Identifying genome-by-childhood trauma interactions for depression using a forest-based approach in the UK Biobank and Adolescent Brain Cognitive Development Study.
   Proc Natl Acad Sci U S A. 2026;123:e2527955123.
   PubMed     Abstract available
   
   
   January 2026
9. TENGSTEDT ANB, Hoye TT, Kristensen TN, Hansen MM, et al
   Evaluating inbreeding and assessing the risk of outbreeding depression in genetic rescue using whole-genome sequence data.
   Proc Natl Acad Sci U S A. 2026;123:e2526216122.
   PubMed     Abstract available
   
   
   November 2025
10. HESTEHAVE S, Florea R, Singleton S, Fedorec AJH, et al
    Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms.
    Proc Natl Acad Sci U S A. 2025;122:e2517405122.
    PubMed     Abstract available
    
    
    September 2025
11. MCCARTHY CI, Zack Ma Z, Monteggia LM, Kavalali ET, et al
    Spontaneous glutamate release activates mGluR signaling to drive rapid antidepressant responses.
    Proc Natl Acad Sci U S A. 2025;122:e2510642122.
    PubMed     Abstract available
    
    
    
12. WANG YH, Fu CL, Chen LB, Zhang CY, et al
    Microglia contribute to bipolar depression through Serinc2-dependent phospholipid synthesis.
    Proc Natl Acad Sci U S A. 2025;122:e2500116122.
    PubMed     Abstract available
    
    
    
13. LI W, Feng Y, Xu Z, Xu X, et al
    Precise antibody delivery to the brain via nanobubble-actuated focused ultrasound alleviates depression.
    Proc Natl Acad Sci U S A. 2025;122:e2421800122.
    PubMed     Abstract available
    
    
    August 2025
14. 
    Correction for Mellya et al., Natural dispersal is better than translocation for reducing risks of inbreeding depression in eastern black rhinoceros (Diceros bicornis michaeli).
    Proc Natl Acad Sci U S A. 2025;122:e2519110122.
    PubMed    
    
    
    June 2025
15. MELLYA RVK, Hopcraft JGC, Mwakilema W, Eblate EM, et al
    Natural dispersal is better than translocation for reducing risks of inbreeding depression in eastern black rhinoceros (Diceros bicornis michaeli).
    Proc Natl Acad Sci U S A. 2025;122:e2414412122.
    PubMed     Abstract available
    
    
    May 2025
16. XIA J, Zou Y, Cui Y, Zhang S, et al
    Physical exercise activates a PVN-NAc oxytocin circuit to relieve stress-induced depressive-like behaviors.
    Proc Natl Acad Sci U S A. 2025;122:e2503675122.
    PubMed     Abstract available
    
    
    April 2025
17. MILLER BR, Gonzaga-Jauregui C, Brigatti KW, de Jong J, et al
    A rare variant in GPR156 associated with depression in a Mennonite pedigree causes habenula hyperactivity and stress sensitivity in mice.
    Proc Natl Acad Sci U S A. 2025;122:e2404754122.
    PubMed     Abstract available
    
    
    November 2024
18. DUARTE Y, Quintana-Donoso D, Moraga-Amaro R, Dinamarca I, et al
    The role of astrocytes in depression, its prevention, and treatment by targeting astroglial gliotransmitter release.
    Proc Natl Acad Sci U S A. 2024;121:e2307953121.
    PubMed     Abstract available
    
    
    September 2024
19. HUR JK, Heffner J, Feng GW, Joormann J, et al
    Language sentiment predicts changes in depressive symptoms.
    Proc Natl Acad Sci U S A. 2024;121:e2321321121.
    PubMed     Abstract available
    
    
    
20. MARTINEZ M, Cai T, Yang B, Zhou Z, et al
    Depressive symptoms during the transition to adolescence: Left hippocampal volume as a marker of social context sensitivity.
    Proc Natl Acad Sci U S A. 2024;121:e2321965121.
    PubMed     Abstract available
    
    
    July 2024
21. PANDEY S, Han W, Li J, Shepard R, et al
    Reversing anxiety by targeting a stress-responsive signaling pathway.
    Proc Natl Acad Sci U S A. 2024;121:e2400078121.
    PubMed     Abstract available
    
    
    
22. RAI S, Stade EC, Giorgi S, Francisco A, et al
    Reply to Wang: Clarifying model performance and language markers of depression across races.
    Proc Natl Acad Sci U S A. 2024;121:e2410449121.
    PubMed    
    
    
    
23. WANG Y
    Large language models for depression prediction.
    Proc Natl Acad Sci U S A. 2024;121:e2409757121.
    PubMed    
    
    
    
24. PECHEVA D, Smith DM, Casey BJ, Woodward LJ, et al
    Sex and mental health are related to subcortical brain microstructure.
    Proc Natl Acad Sci U S A. 2024;121:e2403212121.
    PubMed     Abstract available
    
    
    
25. DE FREITAS J
    Do "Black individuals" really display no linguistic markers of depression?
    Proc Natl Acad Sci U S A. 2024;121:e2410997121.
    PubMed    
    
    
    
26. RAI S, Stade EC, Giorgi S, Francisco A, et al
    Reply to De Freitas: Social media language explains less of the variance in depression of Black individuals than of White individuals.
    Proc Natl Acad Sci U S A. 2024;121:e2411458121.
    PubMed    
    
    
    May 2024
27. JI S, Guo Y, Yan W, Wei F, et al
    PM(2.5) exposure contributes to anxiety and depression-like behaviors via phenyl-containing compounds interfering with dopamine receptor.
    Proc Natl Acad Sci U S A. 2024;121:e2319595121.
    PubMed     Abstract available
    
    
    
28. KNIGHT DJ, Zhang B
    Residential mobility and persistently depressed voting among disadvantaged adults in a large housing experiment.
    Proc Natl Acad Sci U S A. 2024;121:e2306287121.
    PubMed     Abstract available
    
    
    
29. LAVANCHY E, Weir BS, Goudet J
    Detecting inbreeding depression in structured populations.
    Proc Natl Acad Sci U S A. 2024;121:e2315780121.
    PubMed     Abstract available
    
    
    April 2024
30. KUNG CSJ, Steptoe A
    Changes in well-being among socially isolated older people during the COVID-19 pandemic: An outcome-wide analysis.
    Proc Natl Acad Sci U S A. 2024;121:e2308697121.
    PubMed     Abstract available
    
    
    
31. RAI S, Stade EC, Giorgi S, Francisco A, et al
    Key language markers of depression on social media depend on race.
    Proc Natl Acad Sci U S A. 2024;121:e2319837121.
    PubMed     Abstract available
    
    
    December 2023
32. AKIL H, Nestler EJ
    The neurobiology of stress: Vulnerability, resilience, and major depression.
    Proc Natl Acad Sci U S A. 2023;120:e2312662120.
    PubMed    
    
    
    
33. SHIMO Y, Cathomas F, Lin HY, Chan KL, et al
    Social stress induces autoimmune responses against the brain.
    Proc Natl Acad Sci U S A. 2023;120:e2305778120.
    PubMed     Abstract available
    
    
    
34. PAREL ST, Bennett SN, Cheng CJ, Timmermans OC, et al
    Transcriptional signatures of early-life stress and antidepressant treatment efficacy.
    Proc Natl Acad Sci U S A. 2023;120:e2305776120.
    PubMed     Abstract available
    
    
    
35. KRYSTAL JH, Kaye AP, Jefferson S, Girgenti MJ, et al
    Ketamine and the neurobiology of depression: Toward next-generation rapid-acting antidepressant treatments.
    Proc Natl Acad Sci U S A. 2023;120:e2305772120.
    PubMed     Abstract available
    
    
    
36. TURNER CA, Khalil H, Murphy-Weinberg V, Hagenauer MH, et al
    The impact of COVID-19 on a college freshman sample reveals genetic and nongenetic forms of susceptibility and resilience to stress.
    Proc Natl Acad Sci U S A. 2023;120:e2305779120.
    PubMed     Abstract available
    
    
    November 2023
37. KELLEY SW, Fisher AJ, Lee CT, Gallagher E, et al
    Elevated emotion network connectivity is associated with fluctuations in depression.
    Proc Natl Acad Sci U S A. 2023;120:e2216499120.
    PubMed     Abstract available
    
    
    October 2023
38. SEPAHVAND T, Nazari N, Qin T, Rajani V, et al
    Olfactory threat extinction in the piriform cortex: An age-dependent employment of NMDA receptor-dependent long-term depression.
    Proc Natl Acad Sci U S A. 2023;120:e2309986120.
    PubMed     Abstract available
    
    
    June 2023
39. CHAI Y, Gehrman P, Yu M, Mao T, et al
    Enhanced amygdala-cingulate connectivity associates with better mood in both healthy and depressive individuals after sleep deprivation.
    Proc Natl Acad Sci U S A. 2023;120:e2214505120.
    PubMed     Abstract available
    
    
    May 2023
40. MITRA A, Raichle ME, Geoly AD, Kratter IH, et al
    Targeted neurostimulation reverses a spatiotemporal biomarker of treatment-resistant depression.
    Proc Natl Acad Sci U S A. 2023;120:e2218958120.
    PubMed     Abstract available
    
    
    
41. WANG A, Wan X, Zhuang P, Jia W, et al
    High fried food consumption impacts anxiety and depression due to lipid metabolism disturbance and neuroinflammation.
    Proc Natl Acad Sci U S A. 2023;120:e2221097120.
    PubMed     Abstract available
    
    
    April 2023
42. HAO Y, Farah MJ
    Heterogeneity of depression across the socioeconomic spectrum.
    Proc Natl Acad Sci U S A. 2023;120:e2222069120.
    PubMed     Abstract available
    
    

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