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  Colorectal Neoplasms

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08.12.2025

1 Am J Surg
3 Ann Surg Oncol
4 Anticancer Res
1 BMC Cancer
1 Br J Surg
3 Cancer Res
1 Clin Cancer Res
7 Dis Colon Rectum
1 Eur J Cancer
3 Eur J Surg Oncol
2 Int J Cancer
5 Int J Colorectal Dis
1 J Natl Cancer Inst
1 Oncogene


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Am J Surg

  1. CHANG ET, Jiang JK, Chang SC, Wang HS, et al
    The influence of neoadjuvant chemotherapy cycles on surgical complications in metastatic colon cancer.
    Am J Surg. 2025;252:116727.
    PubMed         Abstract available


    Ann Surg Oncol

  2. BOYER ME, Fleming FJ
    Rethinking Surgical Extent-Long-term Outcomes after Resection of T1 and T2 Colon Cancer.
    Ann Surg Oncol. 2025 Dec 3. doi: 10.1245/s10434-025-18831.
    PubMed        

  3. ZHOU Y, Zuo Z, Zhao J, Tan Y, et al
    Development and Validation of Time-to-Event Machine Learning Models for Predicting Disease-Free Survival in Patients with Locally Advanced Colorectal Cancer: A Multicenter Cohort Study.
    Ann Surg Oncol. 2025 Dec 2. doi: 10.1245/s10434-025-18815.
    PubMed         Abstract available

  4. RAQUEL SG, Cate DWGT, Lopez-Baamonde M, Bojesen RD, et al
    Adherence, Compliance Rates, and Response to Training Among Patients Awaiting Colorectal Cancer Surgery: A Secondary Analysis From the PREHAB Multicentre Trial.
    Ann Surg Oncol. 2025 Dec 1. doi: 10.1245/s10434-025-18668.
    PubMed         Abstract available


    Anticancer Res

  5. MUECKE R, Fakhrian K, Gosenheimer R, Schmitz V, et al
    Neoadjuvant Radiochemotherapy for Locally Advanced Rectal Cancer: A Single-institutional Real-world Study.
    Anticancer Res. 2025;45:5513-5521.
    PubMed         Abstract available

  6. KIM J, Han Q, Li S, Kang BM, et al
    The Combination of Recombinant Methioninase and Low-dose Chloroquine Selectively Eradicates Colon-Cancer Cells Without Apparent Toxicity on Co-cultured Normal Fibroblasts.
    Anticancer Res. 2025;45:5313-5320.
    PubMed         Abstract available

  7. FURUKAWA K, Haruki K, Shirai Y, Onda S, et al
    Pulmonary Emphysema Assessed by the Goddard Score Predicts Outcomes After Hepatic Resection for Colorectal Liver Metastases.
    Anticancer Res. 2025;45:5765-5772.
    PubMed         Abstract available

  8. YONEMITSU K, Kasashima H, Fukuoka T, Tanaka A, et al
    Successful Reconstruction of Recurrent Perineal Hernia After APR Using a Vertical Rectus Abdominis Myocutaneous Flap: A Salvage Option for a Refractory Case.
    Anticancer Res. 2025;45:5813-5817.
    PubMed         Abstract available


    BMC Cancer

  9. PAN Y, Ying H, Luo M, Xuan Q, et al
    The co-location of MARCO + macrophages and SPOCK1 + fibroblasts contributes to the poor prognosis and undesirable immunotherapy response in colorectal cancer.
    BMC Cancer. 2025 Nov 28. doi: 10.1186/s12885-025-15397.
    PubMed        


    Br J Surg


  10. Multiple primary tumours in early-onset colorectal cancer: deciphering the risk.
    Br J Surg. 2025;112:znaf244.
    PubMed        


    Cancer Res

  11. ZHAO J, Chen B, Deng Y, Fan L, et al
    ChREBP-Mediated Choline Deprivation and Chemokine Secretion Shape Tumor-Associated Macrophages to Promote Immune Evasion.
    Cancer Res. 2025;85:4701-4717.
    PubMed         Abstract available

  12. DALAL PJ, Shah YM
    Gut Check: Lactobacillus johnsonii Harnesses Bile Acids and Reactive Oxygen Species to Suppress High-Fat Diet-Induced Colorectal Cancer.
    Cancer Res. 2025;85:4579-4581.
    PubMed         Abstract available

  13. ARNOUK SM, Kancheva D, Van Damme H, Courtoy GE, et al
    Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti-PD-1 Immunotherapy.
    Cancer Res. 2025;85:4681-4700.
    PubMed         Abstract available


    Clin Cancer Res

  14. XIA F, Chen Y, Zhou D, Wan J, et al
    Organ Preservation via Immunotherapy-Based Total Neoadjuvant Therapy in Early Low Rectal Cancer (TORCH-E): A Multicenter, Open-label, Single-Arm, Phase II Study.
    Clin Cancer Res. 2025;31:4976-4984.
    PubMed         Abstract available


    Dis Colon Rectum

  15. YEE JT, Eltahir AA, Oduyale OK, Dosch AR, et al
    Brave New World: Analysis of Early Clinical Experience With Molecular Sequencing in the Treatment of Rectal Cancer.
    Dis Colon Rectum. 2025;68:1414-1421.
    PubMed         Abstract available

  16. KARAHAN SN, Oruc M, Erozkan K, Valente MA, et al
    Optimal Timing for Rectal Cancer Surgery After Total Neoadjuvant Therapy: When Does Surgery Get Really Challenging?
    Dis Colon Rectum. 2025;68:1403-1413.
    PubMed         Abstract available

  17. GARFINKLE R, Balvardi S, Boutros M, Fergusson DA, et al
    Neoadjuvant Chemotherapy Without Radiation for Locally Advanced Rectal Cancer: A Meta-analysis of Surgical Outcomes After Total Mesorectal Excision.
    Dis Colon Rectum. 2025;68:1383-1391.
    PubMed         Abstract available

  18. ZHOU J, Lv Q, Yang T, Li Y, et al
    Neoadjuvant Chemotherapy Versus Chemoradiotherapy for Locally Advanced Rectal Cancer: A Multicenter Propensity Score-Matched Study.
    Dis Colon Rectum. 2025;68:1422-1432.
    PubMed         Abstract available


  19. Global Use and Outcomes of Endoscopic Stenting in Acute Malignant Left-Sided Colonic Obstruction: A Secondary Analysis of APOLLO, An International, Prospective Cohort Study.
    Dis Colon Rectum. 2025;68:1458-1467.
    PubMed         Abstract available

  20. KARAHAN SN, Erkaya M, Oruc M, Steele SR, et al
    Risk of Distant Metastasis After Total Neoadjuvant Therapy: Local Regrowth Versus Surgery After Total Neoadjuvant Therapy With Pathologic Near-Complete Response in Rectal Cancer.
    Dis Colon Rectum. 2025;68:1433-1442.
    PubMed         Abstract available

  21. ARARADIAN C, Erlick M, Goodyear S, Kardosh A, et al
    Pilot Study: Identification of the T-Cell Tumor Microenvironment of Premalignant and Malignant Anal Lesions.
    Dis Colon Rectum. 2025;68:1393-1402.
    PubMed         Abstract available


    Eur J Cancer

  22. HEINRICH K, Stintzing S, Weikersthal LFV, Decker T, et al
    Impact of sex on efficacy and safety of 1st-line treatment with FOLFIRI plus cetuximab or bevacizumab in RAS/BRAF wildtype metastatic colorectal cancer - A subgroup analysis of the FIRE-3 (AIO KRK-0306) trial.
    Eur J Cancer. 2025;232:116133.
    PubMed         Abstract available


    Eur J Surg Oncol

  23. YE Q, Liu M, Xu M, Cui M, et al
    Correlation of supportive proton pump inhibitor use during surgery with outcomes in patients with stage I-III colorectal cancer: A propensity score matching study.
    Eur J Surg Oncol. 2025;51:110543.
    PubMed         Abstract available

  24. PAU S, Eglinton T, Wang A, Fischer J, et al
    Pre-operative predictors of completeness of cytoreduction for colorectal peritoneal metastases: a systematic review of radiological, clinicopathological and biomarker-based predictors.
    Eur J Surg Oncol. 2025;51:110537.
    PubMed         Abstract available

  25. O'NEILL MA, Harrold EC, Gillham C, Ryan C, et al
    Immunotherapy for downstaging of locally advanced mismatch repair deficient colorectal cancer: A prospective institutional case series.
    Eur J Surg Oncol. 2025;52:111166.
    PubMed         Abstract available


    Int J Cancer

  26. JAKOBSEN AV, Kronborg C, Ramlov A, Hvid CA, et al
    The prognostic value of cell-free DNA dynamics during chemoradiotherapy in squamous cell carcinomas of the anus.
    Int J Cancer. 2026;158:790-798.
    PubMed         Abstract available

  27. GUADALAJARA H, Dominguez-Tristancho JL, Mateo RF, Leon-Arellano M, et al
    Total neoadjuvant therapy in rectal cancer: The FOREST protocol, a patient-centered approach that clusters two cohorts with different outcomes.
    Int J Cancer. 2026;158:697-706.
    PubMed         Abstract available


    Int J Colorectal Dis

  28. LEVENTI A, Sibbons P, Tsigka A, Korkolis D, et al
    Histological assessment of radiotherapy-induced injury in the anal canal: an exploratory study.
    Int J Colorectal Dis. 2025;40:246.
    PubMed         Abstract available

  29. LI R, Zhao M, Ma Q, Zhang Z, et al
    MRI-defined high-risk rectal cancer patients: comparison of treatment response and survival outcomes between total neoadjuvant therapy and neoadjuvant chemoradiotherapy-a propensity score matched analysis.
    Int J Colorectal Dis. 2025;40:244.
    PubMed         Abstract available

  30. TRUELSEN CG, Kronborg CS, Ramlov A, Hvid CA, et al
    Longitudinal assessment of quality of life and symptom burden in locally advanced rectal cancer patients receiving IMRT-based preoperative radiotherapy: A prospective cohort study.
    Int J Colorectal Dis. 2025;40:239.
    PubMed         Abstract available

  31. SCHRAEPEN C, Bislenghi G, Vanhaecht K, Andre D'Hoore, et al
    Defining key interventions for rectal cancer surgery: a literature review and expert panel consensus.
    Int J Colorectal Dis. 2025;40:241.
    PubMed         Abstract available

  32. LU Z, Yang W, Yang H, Sui X, et al
    Nomogram predicting short- and long-term outcomes in colon cancer based on CT body composition.
    Int J Colorectal Dis. 2025 Dec 2. doi: 10.1007/s00384-025-05016.
    PubMed         Abstract available


    J Natl Cancer Inst

  33. CORONADO GD, Hoffman RM, Llavona-Ortiz J, Rutter CM, et al
    The Centers for Medicare and Medicaid Services and others misunderstand stool testing for colorectal cancer.
    J Natl Cancer Inst. 2025 Dec 1:djaf341. doi: 10.1093.
    PubMed         Abstract available


    Oncogene

  34. YANG LP, Huang JQ, Yeung CW, Zhang QH, et al
    Targeted methylation of cg24067911 suppresses colorectal cancer metastasis through BCL6-ATXN1-CDH1 axis.
    Oncogene. 2025 Dec 2. doi: 10.1038/s41388-025-03638.
    PubMed         Abstract available


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