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  Neoplasms of the CNS

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20.04.2026

1 Acta Neuropathol
2 Am J Clin Oncol
2 BMC Cancer
1 BMC Neurol
2 Cancer
1 Cancer Res
5 Childs Nerv Syst
2 Clin Cancer Res
1 Clin Neuropathol
1 Eur J Cancer
1 J Clin Oncol
13 J Neurooncol
2 J Neurosurg
4 Neuro Oncol
1 Neuroradiology
2 Neurosurgery
1 Oncogene
2 Pediatr Neurosurg
2 PLoS One
1 Radiol Imaging Cancer
1 Rev Neurol (Paris)


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. ZHENG Y, Alzoubi I, Graeber MB, Anand A, et al
    Consensus statement on microglial and macrophage functions in gliomas.
    Acta Neuropathol. 2026;151:39.
    PubMed         Abstract available


    Am J Clin Oncol

  2. BOMMIREDDY A, Angelov L, Suh JH, Murphy ES, et al
    Local Control Outcomes of Patients With Brain Metastases From Small Cell Lung Cancer Treated With Stereotactic Radiosurgery.
    Am J Clin Oncol. 2026 Apr 6. doi: 10.1097/COC.0000000000001325.
    PubMed         Abstract available

  3. OBOH EC, Wu VS, Khlopin M, McClelland S 3rd, et al
    Standard-of-Care Treatment of Glioblastoma: Out-of-Pocket Cost Modeling of Adjuvant Radiation Therapy Duration Across Current-Year Medicaid and Medicare Plans.
    Am J Clin Oncol. 2026 Apr 6. doi: 10.1097/COC.0000000000001324.
    PubMed         Abstract available


    BMC Cancer

  4. CHEONG I, Lau L, Pai S
    Integration of human and mouse single-cell transcriptomes of the developing cerebellum nominates cells-of-origin for group 3 and 4 medulloblastoma.
    BMC Cancer. 2026 Apr 18. doi: 10.1186/s12885-026-16006.
    PubMed        

  5. ESCHEN JT, Jensen LL, Hausmann D, Lind ANR, et al
    SENIPERA Phase 0/1 randomized window-of-opportunity clinical trial of SENIcapoc and PERAmpanel mono- and combination therapy of newly diagnosed glioblastoma: a trial protocol.
    BMC Cancer. 2026 Apr 14. doi: 10.1186/s12885-026-15784.
    PubMed        


    BMC Neurol

  6. XIE H, Pan L, Guo Z, Kang T, et al
    Establishing PDK1-based prognostic biomarkers and identifying targeted inhibitors for glioma prognosis and therapy.
    BMC Neurol. 2026 Apr 16. doi: 10.1186/s12883-026-04885.
    PubMed        


    Cancer

  7. ZHANG J, Wang P, Ren Y, Chen L, et al
    Reply to "Comments on chemoradiotherapy in IDH wild-type/TERT-mutant grade 2/3 gliomas".
    Cancer. 2026;132:e70359.
    PubMed        

  8. KATKURI SN, Vadhithala V, Kumar S, Verma S, et al
    Comments on chemoradiotherapy in IDH wild-type/TERT-mutant grade 2/3 gliomas.
    Cancer. 2026;132:e70358.
    PubMed        


    Cancer Res

  9. YOUNG JS, Cho NW, Lucas CG, Najem H, et al
    IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma.
    Cancer Res. 2026 Apr 13. doi: 10.1158/0008-5472.CAN-25-2922.
    PubMed         Abstract available


    Childs Nerv Syst

  10. CHESNEY KM, McAbee JH, Balu A, Liu J, et al
    Perioperative risk factors predicting CSF leak and retethering following tethered cord release for complex spinal lipomas.
    Childs Nerv Syst. 2026;42:155.
    PubMed         Abstract available

  11. JENKINS A, Guirguis M, Smith P, Witten G, et al
    The role of age and Galassi type in management and surgical outcomes of pediatric middle fossa arachnoid cysts: a systematic review and meta-analysis.
    Childs Nerv Syst. 2026;42:156.
    PubMed         Abstract available

  12. WANG J, Xing Y, Zhao X, Cao Y, et al
    A case report about extracranial skeletal metastases in pediatric diffuse midline glioma, H3 K27-altered.
    Childs Nerv Syst. 2026;42:158.
    PubMed         Abstract available

  13. LEE JS, Lee JI, Shin HJ, Choi JW, et al
    Gamma knife radiosurgery in pediatric neuro-oncology: histology-specific outcomes and age-adapted procedural strategies.
    Childs Nerv Syst. 2026;42:157.
    PubMed         Abstract available

  14. LIU ZM, Mai YY, Zhang P, Zhang LW, et al
    Epidemiology of brain and central nervous system cancers in children and adolescents.
    Childs Nerv Syst. 2026;42:160.
    PubMed         Abstract available


    Clin Cancer Res

  15. WANG F, Liao W, Li C, Duan R, et al
    Lactate-induced lactylation enhances BMAL1 transcription and nuclear translocation, promoting bevacizumab resistance in glioblastoma through VEGFA.
    Clin Cancer Res. 2026 Apr 17. doi: 10.1158/1078-0432.CCR-25-2352.
    PubMed         Abstract available

  16. SIMICIC D, Alcicek S, Blair L, Saint-Germain M, et al
    Ivosidenib and Vorasidenib decrease intratumoral 2-hydroxyglutarate and total choline levels in patients with lower-grade glioma: an in vivo MR Spectroscopy study.
    Clin Cancer Res. 2026 Apr 17. doi: 10.1158/1078-0432.CCR-25-4313.
    PubMed         Abstract available


    Clin Neuropathol

  17. POIDOMANI S, Salzano S, Magro G, Broggi G, et al
    Glioblastoma, IDH-wildtype with melanocytic differentiation: An exceedingly rare morphology and immunophenotype.
    Clin Neuropathol. 2026 Apr 17. doi: 10.5414/NP301736.
    PubMed        


    Eur J Cancer

  18. HAJ MOHAMMAD SF, Spiekman IAC, Verkerk K, Verbeek FAJ, et al
    BRAF(V600E)-mutated central nervous system tumors benefit from treatment with dabrafenib plus trametinib: Results from the Drug Rediscovery Protocol.
    Eur J Cancer. 2026;238:116674.
    PubMed         Abstract available


    J Clin Oncol

  19. WEN PY, Berry DA, Buxton MB, Colman H, et al
    Evaluation of Regorafenib in Newly Diagnosed and Recurrent Glioblastoma: GBM AGILE Phase II/III Bayesian Randomized Platform Trial.
    J Clin Oncol. 2026 Apr 14:JCO2501137. doi: 10.1200/JCO-25-01137.
    PubMed         Abstract available


    J Neurooncol

  20. BOUFFET E, Ramaswamy V, Lafay-Cousin L
    Radiation-sparing management of WNT medulloblastoma of early childhood with high dose chemotherapy: In response to Gupta et al.
    J Neurooncol. 2026;177:95.
    PubMed        

  21. D'ANTONIO F, Rossi S, Carai A, Colafati GS, et al
    Pubertal development and hormonal modulation in pediatric low-grade gliomas: a retrospective cohort study.
    J Neurooncol. 2026;177:96.
    PubMed         Abstract available

  22. WANG Y, Chan WL, Li F, Cai J, et al
    Neurobehavioral outcomes and associated risk factors in pediatric brain tumor survivors.
    J Neurooncol. 2026;177:98.
    PubMed         Abstract available

  23. XU Y, Zhao P, Yao Z, Shen T, et al
    CRYM suppresses glioblastoma progression by inhibiting the TGFbeta1/Smad-EMT signaling pathway.
    J Neurooncol. 2026;177:101.
    PubMed        

  24. SAHU AP, Palsa K, Shenoy G, Slagle-Webb B, et al
    Tumor-associated macrophages promote ferroptosis resistance in glioblastoma by stimulating iron-loaded extracellular vesicle release.
    J Neurooncol. 2026;177:99.
    PubMed         Abstract available

  25. SANTHUMAYOR BA, Domogauer JD, Bernstein K, Donahue B, et al
    Evaluation of disparities in timely stereotactic radiosurgery for brain metastases in a safety net hospital system through a centralized workflow.
    J Neurooncol. 2026;177:102.
    PubMed        

  26. DUZKALIR AH, Yildirim DC, Askeroglu MO, Peker S, et al
    Single-fraction Gamma Knife radiosurgery for pineal region meningiomas: a retrospective single-center cohort of 44 patients.
    J Neurooncol. 2026;177:104.
    PubMed         Abstract available

  27. LIU X, Zeng M, Zhang J, Richard SA, et al
    Microsurgical outcomes and prognostic analysis of cerebellar gliomas; pathology, molecular biomarkers, and novel clinical insights: a retrospective study.
    J Neurooncol. 2026;177:106.
    PubMed        

  28. SALIM HA, Agosto S, Qudah HA, Learned K, et al
    A differentiated thyroid carcinoma-specific graded prognostic assessment for brain metastases: derivation in a 10,306-patient cohort and external validation.
    J Neurooncol. 2026;177:105.
    PubMed         Abstract available

  29. KULAKAUSKIENE D, Kriauciunaite K, Balion Z, Stankevicius E, et al
    Small and medium/large glioblastoma extracellular vesicles differentially regulate endothelial and mitochondrial function in blood-brain barrier and peripheral vasculature models.
    J Neurooncol. 2026;177:103.
    PubMed         Abstract available

  30. NAKANO H, Shiinoki T
    Radiosensitivity index stability across glioma progression: a longitudinal bulk and single-cell analysis.
    J Neurooncol. 2026;177:107.
    PubMed        

  31. HOU Z, Liu X, Zhang C, Sun S, et al
    Alterations in cerebral iron deposition in low-grade glioma-related epilepsy.
    J Neurooncol. 2026;177:108.
    PubMed        

  32. MITTELMAN L, Sistiaga IL, Seenarine N, Syed SA, et al
    Connectome-guided resection of deep-seated brain tumors using tubular retractors: matched cohort outcomes and exploratory quantitative tractometry.
    J Neurooncol. 2026;177:109.
    PubMed        


    J Neurosurg

  33. BAIG AA
    Letter to the Editor. Surgical site infection after cranioplasty for brain tumor.
    J Neurosurg. 2026 Apr 17:1-2. doi: 10.3171/2025.12.JNS253055.
    PubMed        

  34. MCDONALD MF, Athukuri P, Khan AB, Goethe EA, et al
    Seizure-presenting IDH-wildtype glioblastoma and the upregulation of a synaptic signature.
    J Neurosurg. 2026 Apr 10:1-11. doi: 10.3171/2025.11.JNS251412.
    PubMed         Abstract available


    Neuro Oncol


  35. Corrigendum to: Contralateral neurofluid dynamics predict survival in IDH wild-type glioblastoma: A DTI-ALPS and free water imaging study.
    Neuro Oncol. 2026 Apr 10:noag056. doi: 10.1093.
    PubMed        

  36. CLEARY RT, Fu Y, Giles D, Yuan J, et al
    Laser Interstitial Thermal Therapy Enhances Bidirectional Blood-Brain Barrier Permeability in Glioblastoma.
    Neuro Oncol. 2026 Apr 13:noag080. doi: 10.1093.
    PubMed         Abstract available

  37. MOLLER MW, Herrgott GA, Andersen MS, Halle B, et al
    DNA methylation profiling predicts postsurgical regrowth in SF1-lineage nonfunctioning pituitary neuroendocrine tumors.
    Neuro Oncol. 2026;28:728-740.
    PubMed         Abstract available

  38. SHIN Y, Hyung J, Kim S, Lee K, et al
    A novel prognostic model for primary central nervous system lymphoma incorporating clinico-laboratory parameters.
    Neuro Oncol. 2026;28:741-751.
    PubMed         Abstract available


    Neuroradiology

  39. ADWAN H, Stein LV, Becker S, Rodel C, et al
    Intra-arterial chemoperfusion for breast cancer brain metastases: safety and efficacy.
    Neuroradiology. 2026 Apr 10. doi: 10.1007/s00234-026-03988.
    PubMed         Abstract available


    Neurosurgery

  40. HARPER SD, Carson A, Alderete JA, Patel SG, et al
    Choroid Plexus Cauterization Prevents Postoperative Hydrocephalus in Adult Glioblastoma Resection With Ventricular Entry.
    Neurosurgery. 2026 Apr 13. doi: 10.1227/neu.0000000000004036.
    PubMed         Abstract available

  41. ORMOND DR, Badve C, Redjal N, Orringer D, et al
    Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Treatment of Adults With WHO Grade II Diffuse Glioma: Update.
    Neurosurgery. 2026;98:984-991.
    PubMed         Abstract available


    Oncogene

  42. LIU L, Wang R, Cheng K, Bai C, et al
    Correction: Steroid receptor coactivator-1 facilitates METTL3-mediated m6A modification by coactivating NF-kappaB and promotes the malignant progression of glioblastoma.
    Oncogene. 2026 Apr 15. doi: 10.1038/s41388-026-03788.
    PubMed        


    Pediatr Neurosurg

  43. SHANAHAN RM, Wei CZ, Miller T, Deng H, et al
    Gamma Knife Stereotactic Radiosurgery for Pediatric Meningiomas.
    Pediatr Neurosurg. 2026 Apr 10:1-18. doi: 10.1159/000551777.
    PubMed         Abstract available

  44. JOSEPH J, Ganesh S, Raju K
    Pediatric Meningiomas: Clinicopathological Spectrum, Long-Term Outcomes, and Recurrence Predictors.
    Pediatr Neurosurg. 2026 Apr 13:1-19. doi: 10.1159/000551876.
    PubMed         Abstract available


    PLoS One

  45. PICHARDO-ROJAS PS, Tos SM, Mantziaris G, Shaaban A, et al
    Safety and effectiveness of stereotactic radiosurgery for larger hemangioblastomas (>2cc): A multi-center retrospective study.
    PLoS One. 2026;21:e0337000.
    PubMed         Abstract available

  46. ZOU X, Wang P, Nong W, Liu C, et al
    Down-regulation of circ0001361 induces apoptosis and suppresses the progression of glioma.
    PLoS One. 2026;21:e0343681.
    PubMed         Abstract available


    Radiol Imaging Cancer

  47. UM H, Ismail M, Hill VB, Puri S, et al
    Radiomics-based Differentiation of Recurrent Brain Metastases from Treatment Effects: A Multi-Institutional Comparative Study with Advanced Imaging.
    Radiol Imaging Cancer. 2026;8:e250435.
    PubMed         Abstract available


    Rev Neurol (Paris)

  48. HARLAY V, Mira V, Petrirena G, Bertucci A, et al
    Movement disorders due to primary central nervous system lymphoma: An illustrative case and systematic literature review.
    Rev Neurol (Paris). 2026;182:248-258.
    PubMed         Abstract available


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