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Neoplasms of the CNS

Free Subscription Articles published in Cancer Res Retrieve available abstracts of 64 articles: HTML format

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May 2026
1. FRIEDEL RH, Zou H
   Interplay of glioblastoma cells with microglia shape invasive phenotypes during long-distance invasion.
   Cancer Res. 2026 May 12. doi: 10.1158/0008-5472.CAN-26-2075.
   PubMed     Abstract available
   
   
   
2. WANG Y, Sheng X, Yang Y, Liu C, et al
   VGF-Mediated Mitochondrial Remodeling Fuels Lung Adenocarcinoma Brain Metastasis.
   Cancer Res. 2026;86:2104-2125.
   PubMed     Abstract available
   
   
   April 2026
3. FRISKE JD, Cuisin F, Guernalec P, Malone HA, et al
   A Conserved Enhancer Locus in Extrachromosomal DNA and Homogeneously Staining Regions Activates MYC Transcription in Group 3 Medulloblastoma.
   Cancer Res. 2026 Apr 22. doi: 10.1158/0008-5472.CAN-25-4691.
   PubMed     Abstract available
   
   
   
4. YOUNG RG, Esquea EM, Ciraku L, Merzy J, et al
   ACSS2 Suppresses Ferroptosis to Drive Breast Cancer Brain Metastasis.
   Cancer Res. 2026 Apr 22. doi: 10.1158/0008-5472.CAN-25-3006.
   PubMed     Abstract available
   
   
   
5. YOUNG JS, Cho NW, Lucas CG, Najem H, et al
   IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma.
   Cancer Res. 2026 Apr 13. doi: 10.1158/0008-5472.CAN-25-2922.
   PubMed     Abstract available
   
   
   March 2026
6. WANG C, Sun T, He Y, Yu M, et al
   A Deep Learning-Driven Framework Integrating Organoid-Based Functional Validation Identifies Universal Neoantigens from Recurrent Glioma Mutations.
   Cancer Res. 2026 Mar 26. doi: 10.1158/0008-5472.CAN-25-2679.
   PubMed     Abstract available
   
   
   
7. ALVARO-ESPINOSA L, Marquez-Galera A, Priego N, Garcia-Calvo V, et al
   MIF-Induced CD74+ Microglia and Macrophages Promote Progression of Brain Metastasis and are Clinically Relevant Across Central Nervous System Disorders.
   Cancer Res. 2026 Mar 24. doi: 10.1158/0008-5472.CAN-25-4018.
   PubMed     Abstract available
   
   
   
8. VALLEBUONA EJ, Smalley I
   Spatially Resolved Opto-Omics Uncovers Functional Microglial Subtypes in Brain Metastasis.
   Cancer Res. 2026;86:1345-1346.
   PubMed     Abstract available
   
   
   
9. TSUJI T, Hirose H, Sugiyama D, Shindo M, et al
   Microglia Display Heterogeneous Initial Responses to Disseminated Tumor Cells.
   Cancer Res. 2026;86:1414-1434.
   PubMed     Abstract available
   
   
   February 2026
10. JUNTTILA MR, Repellin CE, Salaniwal S, Warne R, et al
    Enozertinib Is a Selective, Brain-Penetrant EGFR Inhibitor for Treating Non-Small Cell Lung Cancers with EGFR Exon 20 and Atypical Mutations.
    Cancer Res. 2026;86:759-772.
    PubMed     Abstract available
    
    
    January 2026
11. NAH GSS, Chong YK, Sulaimi FN, Lee KL, et al
    ETC-501 is a Brain Penetrant MNK Kinase Inhibitor that Potentiates TMZ-Induced Senescence and Sensitizes Glioblastoma Cells to Senolytic Therapy.
    Cancer Res. 2026 Jan 22. doi: 10.1158/0008-5472.CAN-24-4388.
    PubMed     Abstract available
    
    
    
12. KREGER BT, Liang Y, Reilly NM, Spears ME, et al
    CFT1946 Is an Orally Available Brain-Penetrant BRAFV600-Mutant Degrader That Overcomes BRAF Inhibitor Resistance.
    Cancer Res. 2026;86:438-452.
    PubMed     Abstract available
    
    
    
13. SCHUFTAN E, Lu IN, de Faria FW, Inserte C, et al
    Integrated Single-Nucleus and Spatial Transcriptomics Elucidate Heterogeneity and Hypoxia-Driven Organization of Supratentorial Ependymoma.
    Cancer Res. 2026;86:540-555.
    PubMed     Abstract available
    
    
    
14. KRATTLI RP JR, Do AH, El-Khatib SM, Alikhani L, et al
    C5aR1 Inhibition Alleviates Cranial Radiation-Induced Cognitive Decline.
    Cancer Res. 2026;86:255-272.
    PubMed     Abstract available
    
    
    December 2025
15. RIVERA-CARABALLO KA, Lee TJ, Sinha A, Orecchioni M, et al
    Oncolytic HSV-1-Mediated JAG1 Blockade Induces Glioma Senescence-Associated Secretory Phenotype to Increase Macrophage Activation and Cetuximab-Mediated Senolysis.
    Cancer Res. 2025 Dec 18. doi: 10.1158/0008-5472.CAN-25-1402.
    PubMed     Abstract available
    
    
    
16. XIA Z, Liu W, Guo D, Chen L, et al
    circADAMTS12 Inhibits the Antitumor Activity of Microglia to Enable Metastatic Colonization in the Brain.
    Cancer Res. 2025;85:4977-4994.
    PubMed     Abstract available
    
    
    November 2025
17. GANGWANI K, Lu C, Dhanda SK, Sioson E, et al
    The Medulloblastoma Meta-Analysis Portal Enables Integrative Exploration of Clinical and Genomic Data from Patients.
    Cancer Res. 2025 Nov 5:OF1-OF9. doi: 10.1158/0008-5472.CAN-24-4976.
    PubMed     Abstract available
    
    
    October 2025
18. KIM KW, Choi HJ, Lee JH
    White matter injury fuels early progression of glioblastoma.
    Cancer Res. 2025 Oct 1. doi: 10.1158/0008-5472.CAN-25-4362.
    PubMed     Abstract available
    
    
    September 2025
19. KHAN F, Petrosyan E, Liu Y, Bahrami A, et al
    Microglial TBK1 Signaling Promotes Breast Cancer Brain Metastasis.
    Cancer Res. 2025 Sep 18. doi: 10.1158/0008-5472.CAN-25-1791.
    PubMed     Abstract available
    
    
    
20. CUI Y, Phuong K, Abdelfattah NS, Temple HM, et al
    Quantitative Cell Type Specific Immunopeptidome Analysis of Macrophage and Tumor Co-evolution Reveals Therapeutic MHC-I Peptides in Glioblastoma.
    Cancer Res. 2025 Sep 18. doi: 10.1158/0008-5472.CAN-24-4674.
    PubMed     Abstract available
    
    
    
21. AHN JY, Dong W, Puri A, Vasquez M, et al
    Spatial Crosstalk Modeling of the Tumor Microenvironment Identifies CCR5-Mediated Glia-to-Glia Signaling as a Key Regulator of Brain Metastatic Progression.
    Cancer Res. 2025 Sep 16. doi: 10.1158/0008-5472.CAN-25-0237.
    PubMed     Abstract available
    
    
    August 2025
22. PAI B, Ramos SI, Cheng WS, Joshi T, et al
    Spatial Multi-omics Defines a Shared Tumor Infiltrative Signature at the Resection Margin in High-Grade Gliomas.
    Cancer Res. 2025 Aug 4. doi: 10.1158/0008-5472.CAN-24-4708.
    PubMed     Abstract available
    
    
    July 2025
23. LIU G, Zhang H, Chen S, Gao J, et al
    Mitochondrial Calcium Uniporter Links Acetyl-CoA Metabolism and H3K27 Acetylation to Maintain Glioblastoma Stem Cells.
    Cancer Res. 2025 Jul 25. doi: 10.1158/0008-5472.CAN-25-0419.
    PubMed     Abstract available
    
    
    
24. RICHMAN CM, Rasnitsyn A, Holgado BL, Vladoiu M, et al
    Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiation Therapy.
    Cancer Res. 2025 Jul 25. doi: 10.1158/0008-5472.CAN-24-3894.
    PubMed     Abstract available
    
    
    June 2025
25. KHAN KA, Qureshi AA, Xu P, Kuo HY, et al
    Immunological Tolerance to Luciferase and Fluorescent Proteins Using Tol Mice Enables Development of Improved Tumor Models for Investigating Immunity and Metastasis.
    Cancer Res. 2025;85:2165-2178.
    PubMed     Abstract available
    
    
    May 2025
26. BALAKRISHNAN I, Madhavan K, Pierce A, Michlin J, et al
    Development of an Anti-CD99 Antibody Enables Targeting of Diffuse Midline Glioma.
    Cancer Res. 2025 May 27. doi: 10.1158/0008-5472.CAN-24-5027.
    PubMed     Abstract available
    
    
    April 2025
27. SANG Y, Li Y, Song L, Alvarez AA, et al
    Editor's Note: TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3.
    Cancer Res. 2025;85:1342.
    PubMed    
    
    
    March 2025
28. KONG Y, Wang F, Jing R, Zhao Q, et al
    Targeting the SP/KLF Transcriptional Regulatory Network Synergizes with HDAC Inhibition to Impede Progression of H3K27M Diffuse Intrinsic Pontine Glioma.
    Cancer Res. 2025 Mar 7. doi: 10.1158/0008-5472.CAN-24-2227.
    PubMed     Abstract available
    
    
    February 2025
29. NOWICKA Z, Rentzeperis F, Tagal V, Teer JK, et al
    Interactions Between Ploidy and Resource Availability Shape Clonal Evolution in Glioblastoma.
    Cancer Res. 2025 Feb 11. doi: 10.1158/0008-5472.CAN-24-0401.
    PubMed     Abstract available
    
    
    
30. IPPOLITOV D, Lin YH, Spence J, Glogowska A, et al
    The Brain-Penetrant Pan ErbB Inhibitor Poziotinib Effectively Targets HER2+ Breast Cancer Brain Metastases.
    Cancer Res. 2025 Feb 11. doi: 10.1158/0008-5472.CAN-24-1793.
    PubMed     Abstract available
    
    
    January 2025
31. LIU T, Sun T, Chen X, Wu J, et al
    Targeting ARPC1B Overcomes Immune Checkpoint Inhibitor Resistance in Glioblastoma by Reversing Pro-tumorigenic Macrophage Polarization.
    Cancer Res. 2025 Jan 22. doi: 10.1158/0008-5472.CAN-24-2286.
    PubMed     Abstract available
    
    
    
32. ORR BA
    Transcription Factor Fingerprint Provides Clues for Brain Tumor Cell of Origin.
    Cancer Res. 2025;85:195-196.
    PubMed     Abstract available
    
    
    
33. JESSA S, De Cola A, Chandarana B, McNicholas M, et al
    FOXR2 Targets LHX6+/DLX+ Neural Lineages to Drive Central Nervous System Neuroblastoma.
    Cancer Res. 2025;85:231-250.
    PubMed     Abstract available
    
    
    
34. NINOMIYA T, Kemmotsu N, Mukohara F, Magari M, et al
    Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy.
    Cancer Res. 2025 Jan 13. doi: 10.1158/0008-5472.CAN-24-2274.
    PubMed     Abstract available
    
    
    December 2024
35. DRUCKER KL, Jenkins RB, Schramek D
    Switching Drivers: Epigenetic Rewiring to Genetic Progression in Glioma.
    Cancer Res. 2024 Dec 30. doi: 10.1158/0008-5472.CAN-24-4907.
    PubMed     Abstract available
    
    
    
36. WU CY, Chen Y, Lin YJ, Wei KC, et al
    Tumor-Associated Microglia Secrete Extracellular ATP to Support Glioblastoma Progression.
    Cancer Res. 2024;84:4017-4030.
    PubMed     Abstract available
    
    
    November 2024
37. ZHOU Z, Yin X, Sun H, Lu J, et al
    PTBP1 Lactylation Promotes Glioma Stem Cell Maintenance through PFKFB4-Driven Glycolysis.
    Cancer Res. 2024 Nov 21. doi: 10.1158/0008-5472.CAN-24-1412.
    PubMed     Abstract available
    
    
    
38. IZAR B, Kim M
    Peritumoral Venous Vessels: Autobahn and Portal for T cells to Melanoma Brain Metastasis.
    Cancer Res. 2024 Nov 8. doi: 10.1158/0008-5472.CAN-24-4054.
    PubMed     Abstract available
    
    
    
39. CHEN X, Geng Y, Wei G, He D, et al
    Neural Circuitries between the Brain and Peripheral Solid Tumors.
    Cancer Res. 2024;84:3509-3521.
    PubMed     Abstract available
    
    
    October 2024
40. CHEN D, Le SB, Manektalia H, Liu T, et al
    The EP3-ZNF488 Axis Promotes Self-Renewal of Glioma Stem-like Cells to Induce Resistance to Tumor Treating Fields.
    Cancer Res. 2024 Oct 16. doi: 10.1158/0008-5472.CAN-23-3643.
    PubMed     Abstract available
    
    
    
41. RIMKUS TK, Carpenter RL, Sirkisoon S, Zhu D, et al
    Editor's Note: Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44.
    Cancer Res. 2024;84:3310.
    PubMed    
    
    
    September 2024
42. PANG L, Zhou F, Chen P
    Lipid-laden macrophages recycle myelin to feed glioblastoma.
    Cancer Res. 2024 Sep 18. doi: 10.1158/0008-5472.CAN-24-3362.
    PubMed     Abstract available
    
    
    August 2024
43. LEE C, Yu D, Kim HS, Kim KS, et al
    Galectin-9 Mediates the Functions of Microglia in the Hypoxic Brain Tumor Microenvironment.
    Cancer Res. 2024 Aug 29. doi: 10.1158/0008-5472.CAN-23-3878.
    PubMed     Abstract available
    
    
    
44. MACLEOD G, Molaei F, Haider S, Almeida MP, et al
    Fitness Screens Map State-Specific Glioblastoma Stem Cell Vulnerabilities.
    Cancer Res. 2024 Aug 26. doi: 10.1158/0008-5472.CAN-23-4024.
    PubMed     Abstract available
    
    
    
45. JIAO M, Pirozzi CJ, Yu C, Bao X, et al
    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma.
    Cancer Res. 2024 Aug 1. doi: 10.1158/0008-5472.CAN-24-0134.
    PubMed     Abstract available
    
    
    July 2024
46. NAIR NU, Schaffer AA, Gertz EM, Cheng K, et al
    Chromosome 7 gain compensates for chromosome 10 loss in glioma.
    Cancer Res. 2024 Jul 30. doi: 10.1158/0008-5472.CAN-24-1366.
    PubMed     Abstract available
    
    
    April 2024
47. LOW JCM, Cao J, Hesse F, Wright AJ, et al
    Deuterium metabolic imaging differentiates glioblastoma metabolic subtypes and detects early response to chemoradiotherapy.
    Cancer Res. 2024 Apr 18. doi: 10.1158/0008-5472.CAN-23-2552.
    PubMed     Abstract available
    
    
    March 2024
48. HWANG GH, Pazyra-Murphy MF, Seo HS, Dhe-Paganon S, et al
    A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma.
    Cancer Res. 2024;84:872-886.
    PubMed     Abstract available
    
    
    February 2024
49. LI J, Shih LK, Brat DJ
    Integrated Proteogenomics Uncover Mechanisms of Glioblastoma Evolution, Pointing to Novel Therapeutic Targets.
    Cancer Res. 2024 Feb 8. doi: 10.1158/0008-5472.CAN-24-0452.
    PubMed     Abstract available
    
    
    January 2024
50. UNDERHILL HR, Karsy M, Davidson CJ, Hellwig S, et al
    Subclonal Cancer Driver Mutations are Prevalent in the Unresected Peritumoral Edema of Adult Diffuse Gliomas.
    Cancer Res. 2024 Jan 25. doi: 10.1158/0008-5472.CAN-23-2557.
    PubMed     Abstract available
    
    
    
51. ZHAO D, Verhaak RGW
    Defining the role of extrachromosomal DNA amplifications in medulloblastoma.
    Cancer Res. 2024 Jan 4. doi: 10.1158/0008-5472.CAN-23-4025.
    PubMed     Abstract available
    
    
    December 2023
52. MALTA TM, Sabedot TS, Morosini NS, Datta I, et al
    The epigenetic evolution of glioma is determined by the IDH1 mutation status and treatment regimen.
    Cancer Res. 2023 Dec 20. doi: 10.1158/0008-5472.CAN-23-2093.
    PubMed     Abstract available
    
    
    
53. WANG D, Yan K, Yu H, Li H, et al
    Fimepinostat impairs NF-kappaB and PI3K/AKT signaling and enhances gemcitabine efficacy in H3K27M-mutated diffuse intrinsic pontine glioma.
    Cancer Res. 2023 Dec 14. doi: 10.1158/0008-5472.CAN-23-0394.
    PubMed     Abstract available
    
    
    November 2023
54. GUO X, Qiu W, Wang C, Qi Y, et al
    Neuronal activity promotes glioma progression by inducing proneural-to-mesenchymal transition in glioma stem cells.
    Cancer Res. 2023 Nov 14. doi: 10.1158/0008-5472.CAN-23-0609.
    PubMed     Abstract available
    
    
    September 2023
55. YIN J, Seo Y, Rhim J, Jin X, et al
    Crosstalk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem Cells.
    Cancer Res. 2023 Sep 25. doi: 10.1158/0008-5472.CAN-22-3965.
    PubMed     Abstract available
    
    
    May 2023
56. MONDAL I, Das O, Sun R, Gao J, et al
    PP2Ac Deficiency Enhances Tumor Immunogenicity by Activating STING-Type I Interferon Signaling in Glioblastoma.
    Cancer Res. 2023 May 23:CAN-22-3382. doi: 10.1158/0008-5472.CAN-22-3382.
    PubMed     Abstract available
    
    
    
57. JACKSON ER, Duchatel RJ, Staudt DE, Persson ML, et al
    ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma.
    Cancer Res. 2023 May 17:OF1-OF17. doi: 10.1158/0008-5472.CAN-23-0186.
    PubMed     Abstract available
    
    
    
58. BAYIK D, Bartels CF, Lovrenert K, Watson DC, et al
    Correction: Distinct Cell Adhesion Signature Defines Glioblastoma Myeloid-Derived Suppressor Cell Subsets.
    Cancer Res. 2023;83:1757.
    PubMed    
    
    
    
59. JACKSON ER, Duchatel RJ, Staudt DE, Persson ML, et al
    ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.
    Cancer Res. 2023 May 5:CAN-23-0186. doi: 10.1158/0008-5472.CAN-23-0186.
    PubMed     Abstract available
    
    
    April 2023
60. GUETTA-TERRIER C, Karambizi D, Akosman B, Zepecki JP, et al
    Chi3l1 is a modulator of glioma stem cell states and a therapeutic target in glioblastoma.
    Cancer Res. 2023 Apr 27:CAN-21-3629. doi: 10.1158/0008-5472.CAN-21-3629.
    PubMed     Abstract available
    
    
    
61. MIRZAEI R, D'Mello C, Liu M, Nikolic A, et al
    Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor-Initiating Cells.
    Cancer Res. 2023 Apr 17:OF1-OF17. doi: 10.1158/0008-5472.CAN-22-3004.
    PubMed     Abstract available
    
    
    
62. KARREMAN MA, Bauer AT, Solecki G, Berghoff AS, et al
    Active Remodeling of Capillary Endothelium via Cancer Cell-Derived MMP9 Promotes Metastatic Brain Colonization.
    Cancer Res. 2023;83:1299-1314.
    PubMed     Abstract available
    
    
    March 2023
63. ZAMLER DB, Hu J
    Primitive Oligodendrocyte Precursor Cells Are Highly Susceptible to Gliomagenic Transformation.
    Cancer Res. 2023;83:807-808.
    PubMed     Abstract available
    
    
    
64. PINE AR, Cirigliano SM, Singhania R, Nicholson J, et al
    Microenvironment-driven dynamic chromatin changes in glioblastoma recapitulate early neural development at single-cell resolution.
    Cancer Res. 2023 Mar 6:CAN-22-2872. doi: 10.1158/0008-5472.CAN-22-2872.
    PubMed     Abstract available
    
    

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