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  Cytomegalovirus Infection

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Articles published in J Virol

Retrieve available abstracts of 49 articles:
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Single Articles


    October 2025
  1. MEDICA S, Diggins NL, Denton M, Turner RL, et al
    Human cytomegalovirus UL78 is a nuclear-localized GPCR necessary for efficient reactivation from latent infection in CD34(+) hematopoietic progenitor cells.
    J Virol. 2025 Oct 8:e0140225. doi: 10.1128/jvi.01402.
    PubMed     Abstract available


    September 2025
  2. GULIJIAHANI A, Arii J, Isakovic V, Huang JR, et al
    ESCRT-III is recruited by human herpesvirus 6A nuclear egress complex to promote nuclear egress of the nucleocapsid.
    J Virol. 2025;99:e0084425.
    PubMed     Abstract available


  3. BARUAH V, O'Connor CM
    The BTK-DDX41 axis of the STING pathway is activated during cytomegalovirus lytic infection.
    J Virol. 2025 Sep 16:e0104825. doi: 10.1128/jvi.01048.
    PubMed     Abstract available


    August 2025
  4. OSANYINLUSI SA, Baruah V, Groves IJ, Kulp KH, et al
    Human cytomegalovirus-encoded G protein-coupled receptor (GPCR) UL78 regulates viral reactivation.
    J Virol. 2025 Aug 27:e0105725. doi: 10.1128/jvi.01057.
    PubMed     Abstract available


  5. KLINE I, Mokry RL, Xi Y, Passols Manzano M, et al
    Human cytomegalovirus promotes de novo PC synthesis during early virus replication.
    J Virol. 2025 Aug 19:e0057925. doi: 10.1128/jvi.00579.
    PubMed     Abstract available


  6. KUMAR R, Reider IE, Martin M, Simpson JS, et al
    The HCMV tegument protein UL88 degrades MyD88 and reduces innate immune activation.
    J Virol. 2025;99:e0041425.
    PubMed     Abstract available


  7. ZHOU X, Yang L, Cimato G, Frascaroli G, et al
    Increased infectivity of human cytomegalovirus strain TB40/E conferred by variants of the envelope glycoprotein UL128 and the regulatory protein IE2.
    J Virol. 2025 Aug 11:e0064225. doi: 10.1128/jvi.00642.
    PubMed     Abstract available


    July 2025
  8. HANCOCK MH, Caposio P, Collins-McMillen D, Diggins NL, et al
    Cytomegalovirus latency-the sum of subtleties.
    J Virol. 2025 Jul 30:e0066425. doi: 10.1128/jvi.00664.
    PubMed     Abstract available


    June 2025
  9. SCHLEISS MR, Fernandez-Alarcon C, Bierle CJ, Geballe AP, et al
    Replication-deficient whole-virus vaccines against cytomegalovirus induce protective immunity in a guinea pig congenital infection model.
    J Virol. 2025 Jun 11:e0020725. doi: 10.1128/jvi.00207.
    PubMed     Abstract available


    May 2025
  10. STALIUNAITE L, Puhach O, Ostermann E, Rosenke K, et al
    Molecular cloning and host range analysis of three cytomegaloviruses from Mastomys natalensis.
    J Virol. 2025;99:e0214724.
    PubMed     Abstract available


  11. KARTHIGEYAN KP, Connors M, Binuya CR, Gross M, et al
    A human cytomegalovirus prefusion-like glycoprotein B subunit vaccine elicits humoral immunity similar to that of postfusion gB in mice.
    J Virol. 2025 May 8:e0217824. doi: 10.1128/jvi.02178.
    PubMed     Abstract available


    April 2025
  12. COX JB, Nukui M, Murphy EA
    Protein-S-nitrosylation of human cytomegalovirus pp65 reduces its ability to undermine cGAS.
    J Virol. 2025 Apr 17:e0048125. doi: 10.1128/jvi.00481.
    PubMed     Abstract available


  13. WU C, Johnson NM, Yu S, Lo AS, et al
    Persistence of CMV-specific anti-HIV CAR T cells after adoptive immunotherapy.
    J Virol. 2025 Apr 10:e0193324. doi: 10.1128/jvi.01933.
    PubMed     Abstract available


  14. SCHULTZ EP, Ponsness L, Lanchy J-M, Zehner M, et al
    Human cytomegalovirus gH/gL/gO binding to PDGFRalpha provides a regulatory signal activating the fusion protein gB that can be blocked by neutralizing antibodies.
    J Virol. 2025 Apr 9:e0003525. doi: 10.1128/jvi.00035.
    PubMed     Abstract available


    March 2025
  15. HARMENING S, Bogdanow B, Wagner K, Liu F, et al
    Interaction of human cytomegalovirus pUL52 with major components of the viral DNA encapsidation network underlines its essential role in genome cleavage-packaging.
    J Virol. 2025 Mar 10:e0220124. doi: 10.1128/jvi.02201.
    PubMed     Abstract available


    February 2025
  16. MARTIN M, Kumar R, Buchkovich NJ, Norbury CC, et al
    HCMV infection downregulates GPX4 and stimulates lipid peroxidation but does not induce ferroptosis.
    J Virol. 2025;99:e0185124.
    PubMed     Abstract available


  17. CAVANAUGH CM, Betsinger CN, Katchur N, Zhang S, et al
    Effect of host telomerase inhibition on human cytomegalovirus.
    J Virol. 2025 Feb 5:e0157824. doi: 10.1128/jvi.01578.
    PubMed     Abstract available


  18. DUNN DM, Pack LJ, Munger JC
    RAF1 promotes successful human cytomegalovirus replication and is regulated by AMPK-mediated phosphorylation during infection.
    J Virol. 2025 Feb 4:e0186624. doi: 10.1128/jvi.01866.
    PubMed     Abstract available


    January 2025
  19. MEDICA S, Denton M, Diggins NL, Kramer-Hansen O, et al
    Third intracellular loop of HCMV US28 is necessary for signaling and viral reactivation.
    J Virol. 2025;99:e0180124.
    PubMed     Abstract available


  20. CATALDO KM, Roche KL, Monti CE, Dash RK, et al
    The effective multiplicity of infection for HCMV depends on the activity of the cellular 20S proteasome.
    J Virol. 2025;99:e0175124.
    PubMed     Abstract available


    November 2024
  21. HOFSTADTER WA, Park JW, Lum KK, Chen S, et al
    HCMV strain- and cell type-specific alterations in membrane contact sites point to the convergent regulation of organelle remodeling.
    J Virol. 2024;98:e0109924.
    PubMed     Abstract available


  22. OSTERMANN E, Luoto L-M, Clausen M, Virdi S, et al
    E2F3-dependent activation of FAM111B restricts mouse cytomegalovirus replication in primate cells.
    J Virol. 2024 Nov 4:e0134924. doi: 10.1128/jvi.01349.
    PubMed     Abstract available


    October 2024
  23. LENARCIC EM, Hale AE, Vincent HA, Dickmander RJ, et al
    Protein phosphatase 1 suppresses PKR/EIF2alpha signaling during human cytomegalovirus infection.
    J Virol. 2024 Oct 29:e0059024. doi: 10.1128/jvi.00590.
    PubMed     Abstract available


  24. GROVES IJ, O'Connor CM
    Loopy virus or controlled contortionist? 3D regulation of HCMV gene expression by CTCF-driven chromatin interactions.
    J Virol. 2024;98:e0114824.
    PubMed     Abstract available


    September 2024
  25. ZHANG W, Nilles TL, Bream JH, Li H, et al
    Breadth and polyfunctionality of T cell responses to human cytomegalovirus in men who have sex with men: relationship with HIV infection and frailty.
    J Virol. 2024 Sep 4:e0116724. doi: 10.1128/jvi.01167.
    PubMed     Abstract available


    August 2024
  26. BRACKENRIDGE S, John N, He W, Fruh K, et al
    Regulation of the cell surface expression of classical and non-classical MHC proteins by the human cytomegalovirus UL40 and rhesus cytomegalovirus Rh67 proteins.
    J Virol. 2024 Aug 29:e0120624. doi: 10.1128/jvi.01206.
    PubMed     Abstract available


  27. CAI X, Padilla NT, Rosbe K, Tugizov SM, et al
    Breast milk induces the differentiation of monocytes into macrophages, promoting human cytomegalovirus infection.
    J Virol. 2024 Aug 28:e0117724. doi: 10.1128/jvi.01177.
    PubMed     Abstract available


    July 2024
  28. ATANASOFF KE, Parsons AJ, Ophir SI, Lurain N, et al
    A broadly neutralizing human monoclonal antibody generated from transgenic mice immunized with HCMV particles limits virus infection and proliferation.
    J Virol. 2024;98:e0021324.
    PubMed     Abstract available


    June 2024
  29. CIMATO G, Zhou X, Brune W, Frascaroli G, et al
    Human cytomegalovirus glycoprotein variants governing viral tropism and syncytium formation in epithelial cells and macrophages.
    J Virol. 2024 Jun 5:e0029324. doi: 10.1128/jvi.00293.
    PubMed     Abstract available


    April 2024
  30. DOMANICO LF, Dunn GP, Kobiler O, Taylor MP, et al
    A dual fluorescent herpes simplex virus type 1 recombinant reveals divergent outcomes of neuronal infection.
    J Virol. 2024 Apr 23:e0003224. doi: 10.1128/jvi.00032.
    PubMed     Abstract available


  31. COPLEN CP, Jergovic M, Terner EL, Bradshaw CM, et al
    Virological, innate, and adaptive immune profiles shaped by variation in route and age of host in murine cytomegalovirus infection.
    J Virol. 2024 Apr 15:e0198623. doi: 10.1128/jvi.01986.
    PubMed     Abstract available


    March 2024
  32. WU K, Hou YJ, Makrinos D, Liu R, et al
    Characterization of humoral and cellular immunologic responses to an mRNA-based human cytomegalovirus vaccine from a phase 1 trial of healthy adults.
    J Virol. 2024 Mar 25:e0160323. doi: 10.1128/jvi.01603.
    PubMed     Abstract available


  33. ROLLMAN TB, Berkebile ZW, Okae H, Bardwell VJ, et al
    Human trophoblast stem cells restrict human cytomegalovirus replication.
    J Virol. 2024 Mar 7:e0193523. doi: 10.1128/jvi.01935.
    PubMed     Abstract available


    February 2024
  34. KAWASAKI H, Hariyama T, Kosugi I, Meguro S, et al
    Human induced pluripotent stem cells are resistant to human cytomegalovirus infection primarily at the attachment level due to the reduced expression of cell-surface heparan sulfate.
    J Virol. 2024 Feb 12:e0127823. doi: 10.1128/jvi.01278.
    PubMed     Abstract available


    January 2024
  35. MILLER MJ, Akter D, Mahmud J, Chan GC, et al
    Human cytomegalovirus modulates mTORC1 to redirect mRNA translation within quiescently infected monocytes.
    J Virol. 2024 Jan 30:e0188823. doi: 10.1128/jvi.01888.
    PubMed     Abstract available


    October 2023
  36. DIRCK A, Diggins NL, Crawford LB, Perez WD, et al
    HCMV UL8 interaction with beta-catenin and DVL2 regulates viral reactivation in CD34(+) hematopoietic progenitor cells.
    J Virol. 2023;97:e0124123.
    PubMed     Abstract available


  37. O'BRIEN BS, Mokry RL, Schumacher ML, Rosas-Rogers S, et al
    Neutralizing antibodies with neurotropic factor treatment maintain neurodevelopmental gene expression upon exposure to human cytomegalovirus.
    J Virol. 2023 Oct 5:e0069623. doi: 10.1128/jvi.00696.
    PubMed     Abstract available


    September 2023
  38. DOMMA AJ, Henderson LA, Goodrum FD, Moorman NJ, et al
    Human cytomegalovirus attenuates AKT activity by destabilizing insulin receptor substrate proteins.
    J Virol. 2023 Sep 27:e0056323. doi: 10.1128/jvi.00563.
    PubMed     Abstract available


    August 2023
  39. MOY MA, Collins-McMillen D, Crawford L, Parkins C, et al
    Stabilization of the human cytomegalovirus UL136p33 reactivation determinant overcomes the requirement for UL135 for replication in hematopoietic cells.
    J Virol. 2023 Aug 11:e0014823. doi: 10.1128/jvi.00148.
    PubMed     Abstract available


  40. FANUNZA E, Cheng AZ, Auerbach AA, Stefanovska B, et al
    Human cytomegalovirus mediates APOBEC3B relocalization early during infection through a ribonucleotide reductase-independent mechanism.
    J Virol. 2023 Aug 11:e0078123. doi: 10.1128/jvi.00781.
    PubMed     Abstract available


    June 2023
  41. MLERA L, Collins-McMillen D, Zeltzer S, Buehler JC, et al
    Liver X Receptor-Inducible Host E3 Ligase IDOL Targets a Human Cytomegalovirus Reactivation Determinant.
    J Virol. 2023 Jun 20:e0075823. doi: 10.1128/jvi.00758.
    PubMed     Abstract available


  42. KIM JJ, Hong S, Seo JY
    A Cysteine Residue of Human Cytomegalovirus vMIA Protein Plays a Crucial Role in Viperin Trafficking to Control Viral Infectivity.
    J Virol. 2023 Jun 12:e0187422. doi: 10.1128/jvi.01874.
    PubMed     Abstract available


  43. SCHWANKE H, Goncalves Magalhaes V, Schmelz S, Wyler E, et al
    The Cytomegalovirus M35 Protein Directly Binds to the Interferon-beta Enhancer and Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes.
    J Virol. 2023 Jun 8:e0040023. doi: 10.1128/jvi.00400.
    PubMed     Abstract available


    May 2023
  44. IJEZIE EC, O'Dowd JM, Kuan MI, Faeth AR, et al
    HCMV Infection Reduces Nidogen-1 Expression, Contributing to Impaired Neural Rosette Development in Brain Organoids.
    J Virol. 2023;97:e0171822.
    PubMed     Abstract available


    April 2023
  45. FENG M, Chen M, Yuan Y, Liu Q, et al
    Interspecies/Intergroup Complementation of Orthotospovirus Replication and Movement through Reverse Genetics Systems.
    J Virol. 2023;97:e0180922.
    PubMed     Abstract available


  46. HUANG SN, Pan YT, Zhou YP, Wang XZ, et al
    Human Cytomegalovirus IE1 Impairs Neuronal Migration by Downregulating Connexin 43.
    J Virol. 2023 Apr 25:e0031323. doi: 10.1128/jvi.00313.
    PubMed     Abstract available


    March 2023
  47. GHOSH AK, Su YP, Forman M, Keyes RF, et al
    Harnessing the Noncanonical Keap1-Nrf2 Pathway for Human Cytomegalovirus Control.
    J Virol. 2023 Mar 20:e0016023. doi: 10.1128/jvi.00160.
    PubMed     Abstract available


  48. LISTA MJ, Witney AA, Nichols J, Davison AJ, et al
    Strain-Dependent Restriction of Human Cytomegalovirus by Zinc Finger Antiviral Proteins.
    J Virol. 2023 Mar 14:e0184622. doi: 10.1128/jvi.01846.
    PubMed     Abstract available


  49. ALBRIGHT ER, Walter RM, Saffert RT, Kalejta RF, et al
    NFkappaB and Cyclic AMP Response Element Sites Mediate the Valproic Acid and UL138 Responsiveness of the Human Cytomegalovirus Major Immediate Early Enhancer and Promoter.
    J Virol. 2023 Mar 1:e0002923. doi: 10.1128/jvi.00029.
    PubMed     Abstract available


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