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Articles published in Am J Pathol

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Single Articles


    February 2021
  1. MASUZAKI R, Ray KC, Roland J, Zent R, et al
    Integrin beta1 Establishes Liver Microstructure and Modulates Transforming Growth Factor beta during Liver Development and Regeneration.
    Am J Pathol. 2021;191:309-319.
    PubMed     Abstract available


    November 2020
  2. CECI L, Francis H, Zhou T, Giang T, et al
    Knockout of the Tachykinin Receptor 1 in the Mdr2(-/-) (Abcb4(-/-)) Mouse Model of Primary Sclerosing Cholangitis Reduces Biliary Damage and Liver Fibrosis.
    Am J Pathol. 2020;190:2251-2266.
    PubMed     Abstract available


    August 2020
  3. ZHENG D, Jiang Y, Qu C, Yuan H, et al
    Pyruvate kinase M2 (PKM2) tetramerization protects against hepatic stellate cell activation and liver fibrosis.
    Am J Pathol. 2020 Aug 14. pii: S0002-9440(20)30372.
    PubMed     Abstract available


    June 2020
  4. KIKUCHI A, Singh S, Poddar M, Nakao T, et al
    HEPATIC STELLATE CELL-SPECIFIC PLATELET-DERIVED GROWTH FACTOR RECEPTOR alpha LOSS REDUCES FIBROSIS AND PROMOTES REPAIR FOLLOWING HEPATOCELLULAR INJURY.
    Am J Pathol. 2020 Jun 29. pii: S0002-9440(20)30297.
    PubMed     Abstract available


    March 2020
  5. KRISHNAN A, Katsumi T, Guicciardi ME, Azad AI, et al
    TRAIL Receptor Deficiency Promotes the Ductular Reaction, Macrophage Accumulation and Hepatic Fibrosis in the Mdr2(-/-) Mouse.
    Am J Pathol. 2020 Mar 30. pii: S0002-9440(20)30135.
    PubMed     Abstract available


  6. ZHOU Z, Kim JW, Qi J, Eo SK, et al
    Toll-Like Receptor 5 Signaling Ameliorates Liver Fibrosis by Inducing Interferon beta-Modulated IL-1 Receptor Antagonist in Mice.
    Am J Pathol. 2020;190:614-629.
    PubMed     Abstract available


    January 2020
  7. PETRESCU AD, Grant S, Williams E, Frampton G, et al
    Coordinated Targeting of Galanin Receptors on Cholangiocytes and Hepatic Stellate Cells Ameliorates Liver Fibrosis in Mdr2-Knockout Mice.
    Am J Pathol. 2020 Jan 14. pii: S0002-9440(20)30003.
    PubMed     Abstract available


    August 2019
  8. ROCKEY DC, Du Q, Shi Z
    Smooth Muscle alpha-actin Deficiency Leads to Decreased Liver Fibrosis via Impaired Cytoskeletal Signaling in Hepatic Stellate Cells.
    Am J Pathol. 2019 Aug 30. pii: S0002-9440(19)30701.
    PubMed     Abstract available


    September 2018
  9. STROWITZKI MJ, Kirchberg J, Tuffs C, Schiedeck M, et al
    Loss Of Prolyl-Hydroxylase 1 Protects Against Biliary Fibrosis Via Attenuated Activation Of Hepatic Stellate Cells.
    Am J Pathol. 2018 Sep 21. pii: S0002-9440(17)30621.
    PubMed     Abstract available


    July 2018
  10. TSAI HC, Li TH, Huang CC, Huang SF, et al
    Beneficial Effects of the Peroxisome Proliferator-Activated Receptor alpha/gamma Agonist Aleglitazar on Progressive Hepatic and Splanchnic Abnormalities in Cirrhotic Rats with Portal Hypertension.
    Am J Pathol. 2018;188:1608-1624.
    PubMed     Abstract available


    December 2017
  11. KENNEDY L, Hargrove L, Demieville J, Bailey J, et al
    Knockout of l-Histidine Decarboxylase (HDC(-/-)) Prevents Cholangiocyte Damage and Hepatic Fibrosis in Mice Subjected to High-Fat Diet Feeding via Disrupted Histamine/Leptin Signaling.
    Am J Pathol. 2017 Dec 14. pii: S0002-9440(17)30615.
    PubMed     Abstract available


  12. CARPINO G, Cardinale V, Folseraas T, Overi D, et al
    Hepatic stem/progenitor cell activation differs between primary sclerosing and primary biliary cholangitis.
    Am J Pathol. 2017 Dec 14. pii: S0002-9440(17)30740.
    PubMed     Abstract available


  13. WAN Y, McDaniel K, Wu N, Ramos-Lorenzo S, et al
    Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury.
    Am J Pathol. 2017;187:2788-2798.
    PubMed     Abstract available


    September 2017
  14. POZNIAK KN, Pearen MA, Pereira TN, Kramer CS, et al
    Taurocholate induces biliary differentiation of liver progenitor cells causing hepatic stellate cell chemotaxis in the Ductular Reaction: Role in pediatric cystic fibrosis liver disease.
    Am J Pathol. 2017 Sep 18. pii: S0002-9440(17)30375.
    PubMed     Abstract available


    July 2017
  15. KIKUCHI A, Pradhan-Sundd T, Singh S, Nagarajan S, et al
    Platelet-Derived Growth Factor Receptor Alpha Contributes to Human Hepatic Stellate Cell Proliferation and Migration.
    Am J Pathol. 2017 Jul 19. pii: S0002-9440(17)30329.
    PubMed     Abstract available


    May 2017
  16. KYRITSI K, Meng F, Zhou T, Wu N, et al
    Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b.
    Am J Pathol. 2017 May 11. pii: S0002-9440(17)30044.
    PubMed     Abstract available


    April 2017
  17. KUMAR S, Wang J, Shanmukhappa SK, Gandhi CR, et al
    Toll-Like Receptor 4-Independent Carbon Tetrachloride-Induced Fibrosis and Lipopolysaccharide-Induced Acute Liver Injury in Mice: Role of Hepatic Stellate Cells.
    Am J Pathol. 2017 Apr 12. pii: S0002-9440(17)30128.
    PubMed     Abstract available


    January 2017
  18. YANG Z, Liu Y, Qin L, Wu P, et al
    Cathepsin H-Mediated Degradation of HDAC4 for Matrix Metalloproteinase Expression in Hepatic Stellate Cells: Implications of Epigenetic Suppression of Matrix Metalloproteinases in Fibrosis through Stabilization of Class IIa Histone Deacetylases.
    Am J Pathol. 2017 Jan 31. pii: S0002-9440(17)30022.
    PubMed     Abstract available



  19. This Month in AJP.
    Am J Pathol. 2017;187:1.
    PubMed     Abstract available


  20. ELGILANI F, Mao SA, Glorioso JM, Yin M, et al
    Chronic Phenotype Characterization of a Large-Animal Model of Hereditary Tyrosinemia Type 1.
    Am J Pathol. 2017;187:33-41.
    PubMed     Abstract available


    November 2016
  21. HUBEL E, Saroha A, Park WJ, Pewzner-Jung Y, et al
    Sortilin Deficiency Reduces Ductular Reaction, Hepatocyte Apoptosis, and Liver Fibrosis in Cholestatic-Induced Liver Injury.
    Am J Pathol. 2016 Nov 11. pii: S0002-9440(16)30408.
    PubMed     Abstract available


  22. WANG R, Ding Q, De Assuncao TM, Mounajjed T, et al
    Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration.
    Am J Pathol. 2016 Nov 10. pii: S0002-9440(16)30404.
    PubMed     Abstract available


    September 2016
  23. CHEN L, Chen R, Velazquez VM, Brigstock DR, et al
    Fibrogenic Signaling Is Suppressed in Hepatic Stellate Cells through Targeting of Connective Tissue Growth Factor (CCN2) by Cellular or Exosomal MicroRNA-199a-5p.
    Am J Pathol. 2016 Sep 20. pii: S0002-9440(16)30291.
    PubMed     Abstract available


    April 2016
  24. ISAYAMA F, Moore S, Hines IH, Wheeler MD, et al
    Fas Regulates Macrophage Polarization and Fibrogenic Phenotype in a Model of Chronic Ethanol-Induced Hepatocellular Injury.
    Am J Pathol. 2016 Apr 18. pii: S0002-9440(16)30011.
    PubMed     Abstract available


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