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Articles published in Proc Natl Acad Sci U S A

Retrieve available abstracts of 50 articles:
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Single Articles


    October 2025
  1. BERGMAN RE, Keeton CI, Sinha IR, Ling JP, et al
    Distinct and convergent effects of SF3B1 mutations in human breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2505374122.
    PubMed     Abstract available


    September 2025

  2. Correction for Wang et al., Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility.
    Proc Natl Acad Sci U S A. 2025;122:e2518601122.
    PubMed    


  3. SAGLIMBENI J, Esteva E, Canales J, Perez OA, et al
    Peritumoral macrophages recruit eosinophils to promote antitumor immune responses in breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2504645122.
    PubMed     Abstract available


  4. ZHANG J, Zhang J, Han L, Wu S, et al
    Inflammation awakens dormant cancer cells by modulating the epithelial-mesenchymal phenotypic state.
    Proc Natl Acad Sci U S A. 2025;122:e2515009122.
    PubMed     Abstract available


  5. DANG CAO TL, Kawanishi K, Hashimoto S, Hengphasatporn K, et al
    Tumor-expressed GPNMB orchestrates Siglec-9(+) TAM polarization and EMT to promote metastasis in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2503081122.
    PubMed     Abstract available


    August 2025
  6. KHAN F, Liu Y, Whitfield D, Pang L, et al
    Macrophage TBK1 signaling drives the development and outgrowth of breast cancer brain metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2420793122.
    PubMed     Abstract available


  7. KARNER ER, Wang M, Goel HL, Mercurio AM, et al
    GATA3 promotes ferroptosis resistance by repressing integrin beta1 signaling.
    Proc Natl Acad Sci U S A. 2025;122:e2427304122.
    PubMed     Abstract available


  8. PADRAO N, Gregoricchio S, Eickhoff N, Dong J, et al
    TRIM24 as a therapeutic target in endocrine treatment-resistant breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2507571122.
    PubMed     Abstract available


  9. VUILLE JA, Tanriover C, Antmen E, Micalizzi DS, et al
    The E3 ligase HECTD4 regulates COX-2-dependent tumor progression and metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2425621122.
    PubMed     Abstract available


    July 2025
  10. BOYER JA, Rosen EY, Sharma M, Dorso MA, et al
    eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2424286122.
    PubMed     Abstract available



  11. Correction to Supporting Information for Yi et al., Transcriptional suppression of AMPKalpha1 promotes breast cancer metastasis upon oncogene activation.
    Proc Natl Acad Sci U S A. 2025;122:e2516641122.
    PubMed    


  12. HORWITZ E, Dubash TD, Szabolcs A, Wittner BS, et al
    CDKN1B (p27/kip1) enhances drug-tolerant persister CTCs by restricting polyploidy following mitotic inhibitors.
    Proc Natl Acad Sci U S A. 2025;122:e2507203122.
    PubMed     Abstract available


  13. SUN R, Jiang P, Wang Z, Yan B, et al
    DNA2 protein destruction dictates DNA hyperexcision, cGAS-STING activation, and innate immune response in CDK12-deregulated cancers.
    Proc Natl Acad Sci U S A. 2025;122:e2413732122.
    PubMed     Abstract available


  14. ZOU Y, Wang Z, Jiang Q, Kong X, et al
    UFMylation: A supervisor of the HIF1alpha pathway and a potential therapeutic target for anti-PD-1 combination therapy in hypoxic tumors.
    Proc Natl Acad Sci U S A. 2025;122:e2500562122.
    PubMed     Abstract available


  15. GUO J, Li K, Ming Y, Pan Y, et al
    A circular RNA overcomes acquired resistance to BET inhibitors by antagonizing IGF2BP2-mediated c-MYC translation in TNBC.
    Proc Natl Acad Sci U S A. 2025;122:e2504320122.
    PubMed     Abstract available


  16. LIM J, Jung HD, Park SY, Jeon M, et al
    Genome-scale knockout simulation and clustering analysis of drug-resistant breast cancer cells reveal drug sensitization targets.
    Proc Natl Acad Sci U S A. 2025;122:e2425384122.
    PubMed     Abstract available


    June 2025
  17. ZENG W, Guo H, Liu Q, Wong WH, et al
    Improving polygenic prediction from whole-genome sequencing data by leveraging predicted epigenomic features.
    Proc Natl Acad Sci U S A. 2025;122:e2419202122.
    PubMed     Abstract available


  18. OZAKI MK, Zhang Y, Bartlett AQ, de Wilde E, et al
    Reproductive state controls transcription in the murine liver, with implications for breast cancer liver metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2420174122.
    PubMed     Abstract available


  19. DING Q, Liu J, Wang Y, Kim J, et al
    Dual-laser "808 and 1,064 nm" strategy that circumvents the Achilles' heel of photothermal therapy.
    Proc Natl Acad Sci U S A. 2025;122:e2503574122.
    PubMed     Abstract available


    May 2025
  20. FERRERO G, Cardamone MD, Luca F, Bourk E, et al
    Nonproteolytic ubiquitination regulates chromatin occupancy by the NCoR/SMRT/HDAC3 corepressor complex in MCF-7 breast cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2502805122.
    PubMed     Abstract available


    April 2025
  21. CHEN YF, Zhang QH, Zhang ZW, Zhou YJ, et al
    SNX10 deficiency impairs sensitivity to anti-HER2 antibody-drug conjugates via altering HER2 trafficking in HER2-positive breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2417586122.
    PubMed     Abstract available


  22. ZHAO X, Zhao Y, Li Z, Liu H, et al
    Proximity-activated DNA scanning encoded sequencing for massive access to membrane proteins nanoscale organization.
    Proc Natl Acad Sci U S A. 2025;122:e2425000122.
    PubMed     Abstract available


    March 2025

  23. Correction for Qin et al., A signaling molecule from intratumor bacteria promotes trastuzumab resistance in breast cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2502214122.
    PubMed    


  24. STAROSTECKA M, Jeong H, Hasenfeld P, Benito-Garagorri E, et al
    Structural variant and nucleosome occupancy dynamics postchemotherapy in a HER2+ breast cancer organoid model.
    Proc Natl Acad Sci U S A. 2025;122:e2415475122.
    PubMed     Abstract available


    February 2025
  25. YI J, Du J, Chen X, Nie RC, et al
    A circRNA-mRNA pairing mechanism regulates tumor growth and endocrine therapy resistance in ER-positive breast cancer.
    Proc Natl Acad Sci U S A. 2025;122:e2420383122.
    PubMed     Abstract available


  26. LEI L, Song Y, Yang L, Wang Y, et al
    Triethylamine-mediated protonation-deprotonation unlocks dual-drug self assembly to suppress breast cancer progression and metastasis.
    Proc Natl Acad Sci U S A. 2025;122:e2416796122.
    PubMed     Abstract available


    January 2025
  27. QIN G, Shao X, Liu X, Xu J, et al
    A signaling molecule from intratumor bacteria promotes trastuzumab resistance in breast cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2421710122.
    PubMed     Abstract available


  28. ZHENG M, Wang S, Tang K, Kong R, et al
    The CYLD-PARP1 feedback loop regulates DNA damage repair and chemosensitivity in breast cancer cells.
    Proc Natl Acad Sci U S A. 2025;122:e2413890121.
    PubMed     Abstract available


    December 2024
  29. GONZALEZ-FERNANDEZ M, Perry C, Gerhards NM, Francica P, et al
    Docetaxel response in BRCA1,p53-deficient mammary tumor cells is affected by Huntingtin and BAP1.
    Proc Natl Acad Sci U S A. 2024;121:e2402849121.
    PubMed     Abstract available


  30. SINHA A, Saini KK, Chandramouli A, Tripathi K, et al
    ACSL4-mediated H3K9 and H3K27 hyperacetylation upregulates SNAIL to drive TNBC metastasis.
    Proc Natl Acad Sci U S A. 2024;121:e2408049121.
    PubMed     Abstract available


  31. MATSUZAKI T, Fujii M, Noro H, Togo S, et al
    Simultaneous visualization of membrane fluidity and morphology defines adhesion signatures of cancer cells.
    Proc Natl Acad Sci U S A. 2024;121:e2412914121.
    PubMed     Abstract available


    November 2024
  32. DING X, Liang J, Sharko AC, Hilimire TA, et al
    Mediator kinase inhibitors suppress triple-negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors.
    Proc Natl Acad Sci U S A. 2024;121:e2414501121.
    PubMed     Abstract available


  33. ARULRAJ T, Wang H, Deshpande A, Varadhan R, et al
    Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade.
    Proc Natl Acad Sci U S A. 2024;121:e2410911121.
    PubMed     Abstract available


    October 2024
  34. LI C, Kaur A, Pavlidaki A, Spenle C, et al
    Targeting the MAtrix REgulating MOtif abolishes several hallmarks of cancer, triggering antitumor immunity.
    Proc Natl Acad Sci U S A. 2024;121:e2404485121.
    PubMed     Abstract available


  35. BALDASSARRI I, Tavakol DN, Graney PL, Chramiec AG, et al
    An engineered model of metastatic colonization of human bone marrow reveals breast cancer cell remodeling of the hematopoietic niche.
    Proc Natl Acad Sci U S A. 2024;121:e2405257121.
    PubMed     Abstract available



  36. Correction for Zhang et al., HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells.
    Proc Natl Acad Sci U S A. 2024;121:e2418194121.
    PubMed    


  37. ASEMOTA S, Effah W, Holt J, Johnson D, et al
    A molecular switch from tumor suppressor to oncogene in ER+ve breast cancer: Role of androgen receptor, JAK-STAT, and lineage plasticity.
    Proc Natl Acad Sci U S A. 2024;121:e2406837121.
    PubMed     Abstract available


    September 2024
  38. FENG X, Yang C, Huang Y, Su D, et al
    In vivo CRISPR screens identify Mga as an immunotherapy target in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2406325121.
    PubMed     Abstract available


    August 2024
  39. CHIANG HC, Qi L, Mitra P, Huang Y, et al
    R-loop functions in Brca1-associated mammary tumorigenesis.
    Proc Natl Acad Sci U S A. 2024;121:e2403600121.
    PubMed     Abstract available


    July 2024
  40. SHAH OS, Nasrazadani A, Foldi J, Atkinson JM, et al
    Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations.
    Proc Natl Acad Sci U S A. 2024;121:e2322068121.
    PubMed     Abstract available


  41. ZIN I, China A, Khan K, Nag JK, et al
    AKT-dependent nuclear localization of EPRS1 activates PARP1 in breast cancer cells.
    Proc Natl Acad Sci U S A. 2024;121:e2303642121.
    PubMed     Abstract available


  42. ZHOU Q, Yu H, Chen Y, Ren J, et al
    The CRL3(KCTD10) ubiquitin ligase-USP18 axis coordinately regulates cystine uptake and ferroptosis by modulating SLC7A11.
    Proc Natl Acad Sci U S A. 2024;121:e2320655121.
    PubMed     Abstract available


    June 2024
  43. RUAN ML, Ni WX, Chu JCH, Lam TL, et al
    Iridium(III) carbene complexes as potent girdin inhibitors against metastatic cancers.
    Proc Natl Acad Sci U S A. 2024;121:e2316615121.
    PubMed     Abstract available


    May 2024
  44. CHEN J, Liu X, Zou Y, Gong J, et al
    A high-fat diet promotes cancer progression by inducing gut microbiota-mediated leucine production and PMN-MDSC differentiation.
    Proc Natl Acad Sci U S A. 2024;121:e2306776121.
    PubMed     Abstract available


  45. ASHOKAN A, Sarkar S, Kamran MZ, Surnar B, et al
    Simultaneous targeting of peripheral and brain tumors with a therapeutic nanoparticle to disrupt metabolic adaptability at both sites.
    Proc Natl Acad Sci U S A. 2024;121:e2318119121.
    PubMed     Abstract available


  46. GOYETTE MA, Stevens LE, DePinho CR, Seehawer M, et al
    Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.
    Proc Natl Acad Sci U S A. 2024;121:e2322688121.
    PubMed     Abstract available


    April 2024
  47. MONDAL DK, Xie C, Pascal GJ, Buraschi S, et al
    Decorin suppresses tumor lymphangiogenesis: A mechanism to curtail cancer progression.
    Proc Natl Acad Sci U S A. 2024;121:e2317760121.
    PubMed     Abstract available


    March 2024
  48. WANG D, Tang M, Zhang P, Yang K, et al
    Activation of ERbeta hijacks the splicing machinery to trigger R-loop formation in triple-negative breast cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2306814121.
    PubMed     Abstract available


  49. TAYLOR-PHILLIPS S, Jenkinson D, Stinton C, Kunar MA, et al
    Fatigue and vigilance in medical experts detecting breast cancer.
    Proc Natl Acad Sci U S A. 2024;121:e2309576121.
    PubMed     Abstract available


  50. LAMIA KA
    Telling time in tumor samples reveals diversity of clock disruption.
    Proc Natl Acad Sci U S A. 2024;121:e2401496121.
    PubMed    


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