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Articles published in Lancet

Retrieve available abstracts of 58 articles:
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Single Articles


    May 2026
  1. GIOVANNONI G, Airas L, Bove R, Cutter GR, et al
    Efficacy and safety of ocrelizumab in primary progressive multiple sclerosis, including older patients and those with more advanced disease (ORATORIO-HAND): a multicentre, double-blind, randomised, placebo-controlled, phase 3b study.
    Lancet. 2026;407:2195-2207.
    PubMed     Abstract available


  2. HAUSER SL, Giovannoni G, Montalban X, Oh J, et al
    Efficacy and safety of a bodyweight-adjusted higher dose of ocrelizumab in relapsing (MUSETTE) and primary progressive (GAVOTTE) multiple sclerosis: two multicentre, randomised, double-blind, parallel-group phase 3b trials.
    Lancet. 2026;407:2180-2194.
    PubMed     Abstract available


  3. SAMARASEKERA U
    Stephen Hauser: transforming treatment for multiple sclerosis.
    Lancet. 2026;407:2163.
    PubMed    


  4. COCCO E
    Integrating peripheral immune control and brain health in the multiple sclerosis continuum.
    Lancet. 2026;407:2144-2146.
    PubMed    


  5. CLOWSE MEB, Isenberg DA, Merrill JT, Dorner T, et al
    Efficacy and safety of the CD40 ligand inhibitor dapirolizumab pegol in systemic lupus erythematosus (PHOENYCS GO): a randomised, double-blind, placebo-controlled, phase 3 trial.
    Lancet. 2026 May 29:S0140-6736(26)00691-4. doi: 10.1016/S0140-6736(26)00691.
    PubMed     Abstract available


  6. VOLLENHOVEN RV
    Targeting CD40 with dapirolizumab pegol: a new treatment for systemic lupus erythematosus.
    Lancet. 2026 May 29:S0140-6736(26)01008-1. doi: 10.1016/S0140-6736(26)01008.
    PubMed    


  7. MORAND EF, Dall'Era M, Sanchez-Guerrero J, Pearson DR, et al
    Enpatoran, a Toll-like receptor 7/8 inhibitor, in moderate-to-severe systemic lupus erythematosus: findings from Cohort B of a multicentre, international, double-blind, placebo-controlled dose-finding phase 2 trial.
    Lancet. 2026;407:1809-1824.
    PubMed     Abstract available


  8. PRASAD A
    Amita Aggarwal: understanding autoimmune rheumatic diseases.
    Lancet. 2026;407:1673.
    PubMed    


    April 2026
  9. IORIO R
    Is partial complement blockade enough in myasthenia gravis?
    Lancet. 2026 Apr 21:S0140-6736(26)00749-X. doi: 10.1016/S0140-6736(26)00749.
    PubMed    


  10. VU T, Habib AA, Jacob S, Mantegazza R, et al
    Efficacy and safety of cemdisiran siRNA in myasthenia gravis (NIMBLE): a double-blind, randomised, placebo-controlled, phase 3 trial.
    Lancet. 2026 Apr 21:S0140-6736(26)00690-2. doi: 10.1016/S0140-6736(26)00690.
    PubMed     Abstract available


    February 2026
  11. GROARKE EM, Turturice B, Patel BA, Quinn KA, et al
    VEXAS syndrome: a comprehensive review of pathogenesis, clinical spectrum, and therapeutic strategies.
    Lancet. 2026;407:637-648.
    PubMed     Abstract available


    January 2026
  12. ABIZAID A, Mehran R, Oliva A, Chamie D, et al
    Abluminus DES+ sirolimus-eluting stent versus everolimus-eluting stent in patients with diabetes and coronary artery disease (ABILITY Diabetes Global): results from a multicentre, randomised controlled trial.
    Lancet. 2026 Jan 8:S0140-6736(25)02157-9. doi: 10.1016/S0140-6736(25)02157.
    PubMed     Abstract available


    November 2025
  13. FISHER BA
    Nipocalimab for Sjogren's disease-the importance of autoantibodies.
    Lancet. 2025;406:2397-2398.
    PubMed    


  14. GAO J, Li M, Sun M, Yu Y, et al
    Efficacy and safety of allogeneic CD19 CAR NK-cell therapy in systemic lupus erythematosus: a case series in China.
    Lancet. 2025 Nov 12:S0140-6736(25)01671-X. doi: 10.1016/S0140-6736(25)01671.
    PubMed     Abstract available


  15. ZIEGLER AG, Achenbach P, Weiss A, Berner R, et al
    Efficacy of once-daily, high-dose, oral insulin immunotherapy in children genetically at risk for type 1 diabetes (POInT): a European, randomised, placebo-controlled, primary prevention trial.
    Lancet. 2025 Nov 11:S0140-6736(25)01726-X. doi: 10.1016/S0140-6736(25)01726.
    PubMed     Abstract available


    October 2025
  16. CACOUB P, Vieira M, Langford CA, Tazi Mezalek Z, et al
    Large-vessel vasculitis.
    Lancet. 2025;406:2017-2032.
    PubMed     Abstract available


  17. FILIPPI M, Rocca MA
    MS-STAT2: lessons from negative trials in multiple sclerosis.
    Lancet. 2025 Oct 1:S0140-6736(25)01673-3. doi: 10.1016/S0140-6736(25)01673.
    PubMed    


  18. CHATAWAY J, Williams T, Blackstone J, John N, et al
    Effect of repurposed simvastatin on disability progression in secondary progressive multiple sclerosis (MS-STAT2): a phase 3, randomised, double-blind, placebo-controlled trial.
    Lancet. 2025 Oct 1:S0140-6736(25)01039-6. doi: 10.1016/S0140-6736(25)01039.
    PubMed     Abstract available


    September 2025
  19. ZIEGLER AG, Cengiz E, Kay TWH
    The future of type 1 diabetes therapy.
    Lancet. 2025 Sep 19:S0140-6736(25)01438-2. doi: 10.1016/S0140-6736(25)01438.
    PubMed     Abstract available


  20. MATHIEU C, Wych J, Hendriks AEJ, Van Ryckeghem L, et al
    Minimum effective low dose of antithymocyte globulin in people aged 5-25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial.
    Lancet. 2025 Sep 18:S0140-6736(25)01674-5. doi: 10.1016/S0140-6736(25)01674.
    PubMed     Abstract available


    March 2025
  21. BANERJEE SS, Sahai S, Chate GP
    Guillain-Barre syndrome outbreak in Pune: a health emergency.
    Lancet. 2025 Mar 21:S0140-6736(25)00414-3. doi: 10.1016/S0140-6736(25)00414.
    PubMed    


  22. LATEEF S
    India faces major Guillain-Barre syndrome epidemic.
    Lancet. 2025;405:769.
    PubMed    


    January 2025
  23. ACHARYA NR, Ramanan AV, Coyne AB, Dudum KL, et al
    Stopping of adalimumab in juvenile idiopathic arthritis-associated uveitis (ADJUST): a multicentre, double-masked, randomised controlled trial.
    Lancet. 2025;405:303-313.
    PubMed     Abstract available


  24. BENHADOU F, Cogan E
    Targeting IFNbeta in dermatomyositis.
    Lancet. 2025;405:99-101.
    PubMed    


  25. FIORENTINO D, Mangold AR, Werth VP, Christopher-Stine L, et al
    Efficacy, safety, and target engagement of dazukibart, an IFNbeta specific monoclonal antibody, in adults with dermatomyositis: a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial.
    Lancet. 2025;405:137-146.
    PubMed     Abstract available


    November 2024
  26. DE FREMONT GM, Lenfant T, Le Guern V, Costedoat-Chalumeau N, et al
    Therapies for systemic lupus erythematosus.
    Lancet. 2024;404:2163.
    PubMed    


  27. MATUCHANSKY C
    Therapies for systemic lupus erythematosus.
    Lancet. 2024;404:2163.
    PubMed    


  28. HOI A, Igel T, Mok CC, Arnaud L, et al
    Therapies for systemic lupus erythematosus - Authors' reply.
    Lancet. 2024;404:2163-2164.
    PubMed    


  29. XU Q
    Therapies for systemic lupus erythematosus.
    Lancet. 2024;404:2162.
    PubMed    


  30. PABST T, Maurer B
    Therapies for systemic lupus erythematosus.
    Lancet. 2024;404:2162.
    PubMed    


  31. HAGEN M, Muller F, Wirsching A, Kharboutli S, et al
    Treatment of CNS systemic lupus erythematosus with CD19 CAR T cells.
    Lancet. 2024;404:2158-2160.
    PubMed    


    September 2024
  32. LOVE KM, Brown SA
    The promise of once-weekly insulins for type 1 diabetes: update on progress.
    Lancet. 2024;404:1081-1083.
    PubMed    


  33. BERGENSTAL RM, Weinstock RS, Mathieu C, Onishi Y, et al
    Once-weekly insulin efsitora alfa versus once-daily insulin degludec in adults with type 1 diabetes (QWINT-5): a phase 3 randomised non-inferiority trial.
    Lancet. 2024;404:1132-1142.
    PubMed     Abstract available


    August 2024
  34. AL-SAMKARI H, B Bussel J, Miyakawa Y, Broome CM, et al
    Efgartigimod for primary immune thrombocytopenia: the ADVANCE IV trial - Authors' reply.
    Lancet. 2024;404:434.
    PubMed    


  35. JACOBS JW, Booth GS, Stephens LD, Tormey CA, et al
    Efgartigimod for primary immune thrombocytopenia: the ADVANCE IV trial.
    Lancet. 2024;404:433.
    PubMed    


  36. MA RW, Liu K, Xie J
    Efgartigimod for primary immune thrombocytopenia: the ADVANCE IV trial.
    Lancet. 2024;404:433-434.
    PubMed    


    July 2024
  37. SCHETT G, Mackensen A, Mougiakakos D
    CAR T-cell perspectives in lupus - Authors' reply.
    Lancet. 2024;404:336-337.
    PubMed    


  38. GREMESE E, Bruno D, Ferraccioli G
    CAR T-cell perspectives in lupus.
    Lancet. 2024;404:336.
    PubMed    


    June 2024
  39. LAFAYETTE R, Kristensen J, Stone A, Barratt J, et al
    Targeted release of budesonide in primary IgA nephropathy - Authors' reply.
    Lancet. 2024;403:2786.
    PubMed    


  40. ZOU Y, Du X, Zou J
    Targeted release of budesonide in primary IgA nephropathy.
    Lancet. 2024;403:2785-2786.
    PubMed    


  41. HU Y, Zhang Y
    Targeted release of budesonide in primary IgA nephropathy.
    Lancet. 2024;403:2785.
    PubMed    


  42. SAKUMA I, Ishibashi R, Matsue K, Vatner DF, et al
    Primary adrenal insufficiency due to lymphomatoid granulomatosis in a 32-year-old man.
    Lancet. 2024;403:e33.
    PubMed    


    April 2024
  43. HOI A, Igel T, Mok CC, Arnaud L, et al
    Systemic lupus erythematosus.
    Lancet. 2024 Apr 17:S0140-6736(24)00398-2. doi: 10.1016/S0140-6736(24)00398.
    PubMed     Abstract available


  44. KRICKAU T, Naumann-Bartsch N, Aigner M, Kharboutli S, et al
    CAR T-cell therapy rescues adolescent with rapidly progressive lupus nephritis from haemodialysis.
    Lancet. 2024 Apr 17:S0140-6736(24)00424-0. doi: 10.1016/S0140-6736(24)00424.
    PubMed    


    February 2024
  45. KRONBICHLER A, Bajema IM, Bruchfeld A, Mastroianni Kirsztajn G, et al
    Diagnosis and management of ANCA-associated vasculitis.
    Lancet. 2024;403:683-698.
    PubMed     Abstract available


  46. VAN DER HELM-VAN MIL AHM
    Abatacept in individuals with autoantibody-positive arthralgia at risk for rheumatoid arthritis.
    Lancet. 2024 Feb 14:S0140-6736(24)00055-2. doi: 10.1016/S0140-6736(24)00055.
    PubMed    


    January 2024
  47. WEST EE, Woodruff T, Fremeaux-Bacchi V, Kemper C, et al
    Complement in human disease: approved and up-and-coming therapeutics.
    Lancet. 2024;403:392-405.
    PubMed     Abstract available


  48. CHAKER L, Cooper DS, Walsh JP, Peeters RP, et al
    Hyperthyroidism.
    Lancet. 2024 Jan 23:S0140-6736(23)02016-0. doi: 10.1016/S0140-6736(23)02016.
    PubMed     Abstract available


    November 2023
  49. JAKIMOVSKI D, Bittner S, Zivadinov R, Morrow SA, et al
    Multiple sclerosis.
    Lancet. 2023 Nov 7:S0140-6736(23)01473-3. doi: 10.1016/S0140-6736(23)01473.
    PubMed     Abstract available


  50. REICH HN, Barbour SJ
    PROTECTing the kidneys in IgA nephropathy.
    Lancet. 2023 Nov 3:S0140-6736(23)02418-2. doi: 10.1016/S0140-6736(23)02418.
    PubMed    


  51. ROVIN BH, Barratt J, Heerspink HJL, Alpers CE, et al
    Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial.
    Lancet. 2023 Nov 2:S0140-6736(23)02302-4. doi: 10.1016/S0140-6736(23)02302.
    PubMed     Abstract available


  52. SINGH M, Wambua S, Lee SI, Okoth K, et al
    Autoimmune diseases and adverse pregnancy outcomes: an umbrella review.
    Lancet. 2023;402 Suppl 1:S84.
    PubMed     Abstract available


    October 2023
  53. ESPIGOL-FRIGOLE G, Dejaco C, Mackie SL, Salvarani C, et al
    Polymyalgia rheumatica.
    Lancet. 2023;402:1459-1472.
    PubMed     Abstract available


  54. RUSSELL-JONES D, Babazono T, Cailleteau R, Engberg S, et al
    Once-weekly insulin icodec versus once-daily insulin degludec as part of a basal-bolus regimen in individuals with type 1 diabetes (ONWARDS 6): a phase 3a, randomised, open-label, treat-to-target trial.
    Lancet. 2023 Oct 17:S0140-6736(23)02179-7. doi: 10.1016/S0140-6736(23)02179.
    PubMed     Abstract available


  55. SHAH AS, Wolf RM
    Weekly insulin: a paradigm shift in type 1 diabetes therapy.
    Lancet. 2023 Oct 17:S0140-6736(23)02227-4. doi: 10.1016/S0140-6736(23)02227.
    PubMed    


    September 2023
  56. BROOME CM, McDonald V, Miyakawa Y, Carpenedo M, et al
    Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial.
    Lancet. 2023 Sep 28:S0140-6736(23)01460-5. doi: 10.1016/S0140-6736(23)01460.
    PubMed     Abstract available


  57. MAHAMAD S, Arnold DM
    Inhibition of neonatal Fc receptor as a treatment for immune thrombocytopenia.
    Lancet. 2023 Sep 28:S0140-6736(23)01836-6. doi: 10.1016/S0140-6736(23)01836.
    PubMed    


  58. SCHETT G, Mackensen A, Mougiakakos D
    CAR T-cell therapy in autoimmune diseases.
    Lancet. 2023 Sep 22:S0140-6736(23)01126-1. doi: 10.1016/S0140-6736(23)01126.
    PubMed     Abstract available


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