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  Autoimmune Disorders

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Articles published in J Immunol

Retrieve available abstracts of 52 articles:
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Single Articles


    June 2025
  1. JIANG K, Xu Y, Wang Y, Yin N, et al
    Deciphering the role of IL-17D, its newly identified receptor CD93, and IL-17D-CD93 axis in health and disease.
    J Immunol. 2025;214:1113-1122.
    PubMed     Abstract available


  2. ZHEN Y, Shao WH
    WDFY1-expressing follicular dendritic cells play a critical role in lupus development in cGVHD mouse model.
    J Immunol. 2025;214:1160-1172.
    PubMed     Abstract available


    May 2025
  3. CHEN N, Wu J, Sun D, Kaplan HJ, et al
    Mice deficient of G-protein coupled receptor 3 (GPR3) developed severe experimental autoimmune uveitis (EAU) through increased effector T cell activities.
    J Immunol. 2025 May 17:vkaf099. doi: 10.1093.
    PubMed     Abstract available


    April 2025
  4. TURICEK DP, Wan X
    Decoding autoimmunity: HLA-DQbeta and type 1 diabetes.
    J Immunol. 2025 Apr 28:vkaf070. doi: 10.1093.
    PubMed    


  5. ZHENG G, Oo TT, Janjam SSS, Ellis C, et al
    An antigen-less pro-vaccine for treating autoimmunity.
    J Immunol. 2025 Apr 24:vkaf068. doi: 10.1093.
    PubMed     Abstract available


  6. AHN SH, Halgren K, Grzesiak G, MacRenaris KW, et al
    Autoimmune regulator deficiency causes sterile epididymitis and impacts male fertility through disruption of inorganic physiology.
    J Immunol. 2025 Apr 23:vkaf054. doi: 10.1093.
    PubMed     Abstract available


  7. DICILLO EB, Pisetsky DS, Svenungsson E, Diaz-Gallo LM, et al
    Characterization of autoantibody profiles in clusters of systemic lupus erythematosus using a novel autoantigen discovery technology.
    J Immunol. 2025 Apr 3:vkae025. doi: 10.1093.
    PubMed     Abstract available


    March 2025
  8. SUAN D, Moore J, Goodnow CC
    Can autoimmune disease be cured by deep CD19+ cell depletion?
    J Immunol. 2025 Mar 21:vkaf008. doi: 10.1093.
    PubMed     Abstract available


  9. HUI CW, Wu WC, Tong TK, Shiu C, et al
    Discovery of a new anti-gammac antibody in clinical development for the treatment of autoimmune diseases.
    J Immunol. 2025 Mar 12:vkae020. doi: 10.1093.
    PubMed     Abstract available


    January 2025
  10. HIGDON LE, Cooney LA, Serti E, Suwannasaen D, et al
    Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes.
    J Immunol. 2025;214:12-22.
    PubMed     Abstract available


    October 2024
  11. PENG W, Merlo LMF, Grabler S, Montgomery JD, et al
    IDO2 Drives Autoantibody Production and Joint Inflammation in a Preclinical Model of Arthritis by Repressing Runx1 Function in B Cells.
    J Immunol. 2024 Oct 14:ji2400445. doi: 10.4049/jimmunol.2400445.
    PubMed     Abstract available


  12. TAYLOR JP, Blum SI, Graffeo HC, Shang Q, et al
    The Type 1 Diabetes-Associated Single Nucleotide Polymorphism rs1990760 in IFIH1 Is Associated with Increased Basal Type I IFNs and IFN-stimulated Gene Expression.
    J Immunol. 2024 Oct 7:ji2400344. doi: 10.4049/jimmunol.2400344.
    PubMed     Abstract available


  13. LEBER A, Hontecillas R, Tubau-Juni N, Fitch SN, et al
    Immunometabolic Mechanisms of LANCL2 in CD4+ T Cells and Phagocytes Provide Protection from Systemic Lupus Erythematosus.
    J Immunol. 2024 Oct 4:ji2400127. doi: 10.4049/jimmunol.2400127.
    PubMed     Abstract available


    September 2024
  14. ZHONG B, Zhou JQ, Lyu X, Liu H, et al
    Anti-Heat Shock Protein 70 Autoantibodies from Patients with Idiopathic Pulmonary Fibrosis Epigenetically Enhance Lung Fibroblast Apoptosis Resistance and Bcl-2 Expression.
    J Immunol. 2024 Sep 9:ji2400106. doi: 10.4049/jimmunol.2400106.
    PubMed     Abstract available


  15. LIU JQ, Jabbari A, Lin CH, Akkanapally V, et al
    IL-27 Gene Therapy Ameliorates IPEX Syndrome Caused by Germline Mutation of Foxp3 Gene: A Major Role for Induction of IL-10.
    J Immunol. 2024;213:559-566.
    PubMed     Abstract available


    August 2024
  16. BLEVINS LK, Khan DMIO, Crawford RB, O'Neill C, et al
    CD9 and Aryl Hydrocarbon Receptor Are Markers of Human CD19+CD14+ Atypical B Cells and Are Dysregulated in Systemic Lupus Erythematous Disease.
    J Immunol. 2024 Aug 30:ji2400193. doi: 10.4049/jimmunol.2400193.
    PubMed     Abstract available


  17. SANTANA S, Papillion A, Foote JB, Bachus H, et al
    Cutting Edge: Low-dose Recombinant IL-2 Treatment Prevents Autoantibody Responses in Systemic Lupus Erythematosus via Regulatory T Cell-independent Depletion of T Follicular Helper Cells.
    J Immunol. 2024 Aug 28:ji2400264. doi: 10.4049/jimmunol.2400264.
    PubMed     Abstract available


  18. GREBINOSKI S, Pieklo G, Zhang Q, Visperas A, et al
    Regulatory T Cell Insufficiency in Autoimmune Diabetes Is Driven by Selective Loss of Neuropilin-1 on Intraislet Regulatory T Cells.
    J Immunol. 2024 Aug 7:ji2300216. doi: 10.4049/jimmunol.2300216.
    PubMed     Abstract available


  19. ZHANG J, Ji H, Liu M, Zheng M, et al
    Mitochondrial DNA Programs Lactylation of cGAS to Induce IFN Responses in Patients with Systemic Lupus Erythematosus.
    J Immunol. 2024 Aug 2:ji2300758. doi: 10.4049/jimmunol.2300758.
    PubMed     Abstract available


    July 2024
  20. CHIU H, Weinstein KN, Spath S, Hu A, et al
    SKI Regulates Medullary Thymic Epithelial Cell Differentiation to Control Peripheral T Cell Responses in Mice.
    J Immunol. 2024;213:52-62.
    PubMed     Abstract available


  21. PATINO-MARTINEZ E, Nakabo S, Jiang K, Carmona-Rivera C, et al
    The Aconitate Decarboxylase 1/Itaconate Pathway Modulates Immune Dysregulation and Associates with Cardiovascular Disease Markers and Disease Activity in Systemic Lupus Erythematosus.
    J Immunol. 2024 Jul 1:ji2400241. doi: 10.4049/jimmunol.2400241.
    PubMed     Abstract available


    June 2024
  22. VISWANATH V, Mistry S, Cabrera-Ghayouri S, Leang R, et al
    Sustained Alleviation of Autoimmunity by Activating alpha2B-adrenergic Receptors.
    J Immunol. 2024 Jun 28:ji2300893. doi: 10.4049/jimmunol.2300893.
    PubMed     Abstract available


  23. CARBONE F, Colamatteo A, La Rocca C, Lepore MT, et al
    Metabolic Plasticity of Regulatory T Cells in Health and Autoimmunity.
    J Immunol. 2024;212:1859-1866.
    PubMed     Abstract available


  24. VEMULAWADA C, Renavikar PS, Crawford MP, Steward-Tharp S, et al
    Disruption of IFNgamma, GZMB, PRF1, or LYST Results in Reduced Suppressive Function in Human CD8+ T Cells.
    J Immunol. 2024;212:1722-1732.
    PubMed     Abstract available


    May 2024
  25. WON KD, Gil Gonzalez L, Cruz-Leal Y, Pavon Oro A, et al
    Antagonism of the Platelet-Activating Factor Pathway Mitigates Inflammatory Adverse Events Driven by Anti-erythrocyte Antibody Therapy in Mice.
    J Immunol. 2024;212:1531-1539.
    PubMed     Abstract available


  26. DAI YD, Du W, Wang Y, Hu WY, et al
    A Targeted Deep Sequencing Method to Quantify Endogenous Retrovirus Gag Sequence Variants and Open Reading Frames Expressed in Nonobese Diabetic Mice.
    J Immunol. 2024 May 13:ji2300660. doi: 10.4049/jimmunol.2300660.
    PubMed     Abstract available


    April 2024
  27. TAO Q, Chen Y, Liang Q, Shi J, et al
    Puerarin Alleviates Experimental Autoimmune Thyroiditis by Regulating Macrophages.
    J Immunol. 2024 Apr 26:ji2300779. doi: 10.4049/jimmunol.2300779.
    PubMed     Abstract available


  28. LORANT AK, Yoshida AE, Gilbertson EA, Chu T, et al
    Integrin alphavbeta3 Limits Cytokine Production by Plasmacytoid Dendritic Cells and Restricts TLR-Driven Autoimmunity.
    J Immunol. 2024 Apr 12:ji2300290. doi: 10.4049/jimmunol.2300290.
    PubMed     Abstract available


  29. DE GEORGE DJ, Jhala G, Selck C, Trivedi P, et al
    Altering beta Cell Antigen Exposure to Exhausted CD8+ T Cells Prevents Autoimmune Diabetes in Mice.
    J Immunol. 2024 Apr 8:ji2300785. doi: 10.4049/jimmunol.2300785.
    PubMed     Abstract available


  30. FRANK C, Salapa HE, Allen KJH, Levin MC, et al
    Antibody-Mediated Depletion of Autoreactive T Lymphocytes through PD-1 Improves Disease Outcomes and Visualizes T Cell Activation in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2024 Apr 5:ji2300751. doi: 10.4049/jimmunol.2300751.
    PubMed     Abstract available


  31. WU J, Han K, Sack MN
    Targeting NAD+ Metabolism to Modulate Autoimmunity and Inflammation.
    J Immunol. 2024;212:1043-1050.
    PubMed     Abstract available


    March 2024
  32. COSTANZO A, Clarke D, Holt M, Sharma S, et al
    Repositioning the Early Pathology of Type 1 Diabetes to the Extraislet Vasculature.
    J Immunol. 2024 Mar 1:ji2300769. doi: 10.4049/jimmunol.2300769.
    PubMed     Abstract available


    February 2024
  33. KAGOHASHI K, Sasaki Y, Ozawa K, Tsuchiya T, et al
    Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation.
    J Immunol. 2024 Feb 5:ji2300202. doi: 10.4049/jimmunol.2300202.
    PubMed     Abstract available


  34. DUAN S, Li Q, Wang F, Kuang W, et al
    Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris.
    J Immunol. 2024;212:375-388.
    PubMed     Abstract available


    January 2024
  35. DAR AA, Ortega Y, Aktas S, Wu K, et al
    CRL4b Inhibition Ameliorates Experimental Autoimmune Encephalomyelitis Progression.
    J Immunol. 2024 Jan 24:ji2300754. doi: 10.4049/jimmunol.2300754.
    PubMed     Abstract available


  36. YANDAMURI SS, Filipek B, Lele N, Cohen I, et al
    A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases.
    J Immunol. 2024 Jan 22:ji2300015. doi: 10.4049/jimmunol.2300015.
    PubMed     Abstract available


  37. TOMALA J, Cao SD, Spangler JB
    Engineering Anticytokine Antibodies for Immune Modulation.
    J Immunol. 2024;212:225-234.
    PubMed     Abstract available


  38. HAN K, Xu J, Xie F, Crowther J, et al
    Engineering Strategies to Modulate the Gut Microbiome and Immune System.
    J Immunol. 2024;212:208-215.
    PubMed     Abstract available


  39. KLUG N, Burke J, Scott E
    Rational Engineering of Islet Tolerance via Biomaterial-Mediated Immune Modulation.
    J Immunol. 2024;212:216-224.
    PubMed     Abstract available


    December 2023
  40. FLYNN AL, Gans J, Escobedo J, Zhu C, et al
    RGS1 Modulates Autophagic and Metabolic Programs and Is a Critical Mediator of Human Regulatory T Cell Function.
    J Immunol. 2023;211:1656-1668.
    PubMed     Abstract available


    November 2023
  41. SONI C, Makita S, Eichinger A, Serpas L, et al
    Cutting Edge: TLR2 Signaling in B Cells Promotes Autoreactivity to DNA via IL-6 Secretion.
    J Immunol. 2023;211:1475-1480.
    PubMed     Abstract available


  42. LU Y, Chiang J, Zhang R, Roche PA, et al
    TRAF6 and TRAF2/3 Binding Motifs in CD40 Differentially Regulate B Cell Function in T-Dependent Antibody Responses and Dendritic Cell Function in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2023 Nov 3:ji2300607. doi: 10.4049/jimmunol.2300607.
    PubMed     Abstract available


  43. MONSON N, Smith C, Greenberg H, Plumb P, et al
    VH2+ Antigen-Experienced B Cells in the Cerebrospinal Fluid Are Expanded and Enriched in Pediatric Anti-NMDA Receptor Encephalitis.
    J Immunol. 2023;211:1332-1339.
    PubMed     Abstract available


  44. AKBAR I, Tang R, Baillargeon J, Roy AP, et al
    Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2023 Nov 1:ji2300526. doi: 10.4049/jimmunol.2300526.
    PubMed     Abstract available


  45. PELLERIN A, Tan Y, Lu S, Bonegio RG, et al
    Genetic Reduction of IRF5 Expression after Disease Initiation Reduces Disease in a Mouse Lupus Model by Impacting Systemic and End-Organ Pathogenic Pathways.
    J Immunol. 2023;211:1308-1319.
    PubMed     Abstract available


    October 2023
  46. RACINE JJ, Misherghi A, Dwyer JR, Maser R, et al
    HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice.
    J Immunol. 2023 Oct 25:ji2300303. doi: 10.4049/jimmunol.2300303.
    PubMed     Abstract available


  47. SOUKOU-WARGALLA S, Kilian C, Velasquez LN, Machicote A, et al
    Tr1 Cells Emerge and Suppress Effector Th17 Cells in Glomerulonephritis.
    J Immunol. 2023 Oct 18:ji2300305. doi: 10.4049/jimmunol.2300305.
    PubMed     Abstract available


  48. JORDAN TJM, Chen J, Li N, Burette S, et al
    The Eotaxin-1/CCR3 Axis and Matrix Metalloproteinase-9 Are Critical in Anti-NC16A IgE-Induced Bullous Pemphigoid.
    J Immunol. 2023;211:1216-1223.
    PubMed     Abstract available


  49. GILLES A, Hu L, Virdis F, Sant'Angelo DB, et al
    The MHC Class II Antigen-Processing and Presentation Pathway Is Dysregulated in Type 1 Diabetes.
    J Immunol. 2023 Oct 9:ji2300213. doi: 10.4049/jimmunol.2300213.
    PubMed     Abstract available


  50. MOK MY, Luo CY, Huang FP, Kong WY, et al
    IL-33 Orchestrated the Interaction and Immunoregulatory Functions of Alternatively Activated Macrophages and Regulatory T Cells In Vitro.
    J Immunol. 2023;211:1134-1143.
    PubMed     Abstract available


    September 2023
  51. NEW JS, Dizon BLP, King RG, Greenspan NS, et al
    B-1 B Cell-Derived Natural Antibodies against N-Acetyl-d-Glucosamine Suppress Autoimmune Diabetes Pathogenesis.
    J Immunol. 2023 Sep 25:ji2300264. doi: 10.4049/jimmunol.2300264.
    PubMed     Abstract available


  52. MORIN F, Singh N, Mdzomba JB, Dumas A, et al
    Correction: Conditional Deletions of Hdc Confirm Roles of Histamine in Anaphylaxis and Circadian Activity but Not in Autoimmune Encephalomyelitis.
    J Immunol. 2023 Sep 11:ji2300549. doi: 10.4049/jimmunol.2300549.
    PubMed     Abstract available


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