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Articles published in J Immunol

Retrieve available abstracts of 78 articles:
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Single Articles


    May 2026
  1. PATINO-MARTINEZ E, Hajihosseini M, Hanata N, Jiang K, et al
    Longitudinal multiomic and spatial transcriptomic profiling of lupus nephritis progression in a murine model.
    J Immunol. 2026;215:vkag100.
    PubMed     Abstract available


  2. AKBAR I, Arokia Doss PMI, Patel PU, Surury B, et al
    Myelin antigen-specific effector CD8+ T cells induce chronic CNS autoimmunity in a CD4+ T cell-dependent manner.
    J Immunol. 2026;215:vkag107.
    PubMed     Abstract available


  3. ROMO-TENA J, Sengupta S, Carmona-Rivera C, Nakabo S, et al
    Preconditioning determines engraftment and therapeutic efficacy of anti-CD19 CAR-T cells in murine lupus.
    J Immunol. 2026;215:vkag112.
    PubMed     Abstract available


    April 2026
  4. AL-HALLAF R, Agha Z, Caturegli P, Rosenberg A, et al
    Leveraging a naturally occurring IgM autoantibody to target diabetogenic T cells: a precision medicine approach to type 1 diabetes.
    J Immunol. 2026;215:vkag056.
    PubMed     Abstract available


  5. HORNICK EL, Oxley K, Debreceni IL, Wieting N, et al
    Syk inhibition limits autoimmunity and abnormal B cell phenotype and function in mice with B cell-specific TRAF3 deficiency.
    J Immunol. 2026;215:vkag049.
    PubMed     Abstract available


  6. KHANDELWAL S, Chen J, Myoung SS, Lee GM, et al
    The influence of nuclear antigen form on complement activation by systemic lupus erythematosus antinuclear antibody immune complexes determined by a novel immunocapture assay.
    J Immunol. 2026;215:vkag088.
    PubMed     Abstract available


  7. SHANG XY, Zhang R, Tan LG, Wang HY, et al
    The autoantibody beta1-AA contributes to N/OFQ-exacerbated ventricular arrhythmias following acute myocardial ischemia.
    J Immunol. 2026;215:vkag072.
    PubMed     Abstract available


  8. ZHU Y, Choi SC, Shlomchik MJ, Morel L, et al
    GLUT1-mediated glucose flux constrains autoreactive but not foreign antigen-specific B-cell responses.
    J Immunol. 2026;215:vkag092.
    PubMed     Abstract available


  9. GANUGULA R, Babalola KT, Arora M, Maruvada V, et al
    Combined cyclosporine A and urolithin A therapy ameliorates murine lupus nephritis.
    J Immunol. 2026;215:vkag087.
    PubMed     Abstract available


    March 2026
  10. PREMACHANDRAN S, Groh AMR, Sinott A, Senthil S, et al
    Margins of control: ventricular brain borders as architects in central nervous system autoimmunity.
    J Immunol. 2026;215.
    PubMed     Abstract available


  11. YIN M, Hiam-Galvez KJ, Proekt I, Chan J, et al
    Immune checkpoints in a genetically engineered mouse model of spontaneous autoimmune uveitis.
    J Immunol. 2026;215:vkaf334.
    PubMed     Abstract available


    February 2026
  12. MIZUNO Y, Matsushita H, Fukushima Y, Kobuchi S, et al
    Endothelial semaphorin 6D controls immune responses under cold stress through regulation of sympathetic innervation.
    J Immunol. 2026;215:vkaf362.
    PubMed     Abstract available


  13. AMDARE N, Ali R, Manganaro A, Baker JC, et al
    Islet-derived T cells from both mice and humans recognize conserved insulin A-chain peptides presented by HLA-C*03:04.
    J Immunol. 2026;215:vkaf381.
    PubMed     Abstract available


  14. CHEN J, Fu L, Gong Y, Liao L, et al
    IFNgamma/JAK/STAT1/CD38 pathway in SH2D1Bhigh NK cells: Implications for inflammation in type 1 diabetes.
    J Immunol. 2026;215:vkaf347.
    PubMed     Abstract available


    December 2025
  15. CONWAY H, Bernard J, Ramos R, Zahran S, et al
    Altered B cell metabolic pathways characterize type 1 diabetes progression.
    J Immunol. 2025 Dec 27:vkaf330. doi: 10.1093.
    PubMed     Abstract available


  16. OLEINIKA K, Correia Ferreira A, Mouftakir S, Castrillon C, et al
    Dynamic control of autoreactive B cells from spontaneous germinal centers.
    J Immunol. 2025;214:3208-3217.
    PubMed     Abstract available


  17. ROY U, Raghavan SC
    Regulation of B-cell development and differentiation by microRNAs during immune response and their implications in immunological disorders.
    J Immunol. 2025;214:3199-3207.
    PubMed     Abstract available


  18. PANDEY JP
    Immunoglobulin GM (gamma marker) allotypes and their role in immune response and disease susceptibility.
    J Immunol. 2025;214:3181-3187.
    PubMed     Abstract available


    November 2025
  19. DIAS DA ROCHA LIMA A, De Oliveira MG, Ferrari B, C Fonseca R, et al
    Dimethyl fumarate protects from experimental autoimmune encephalomyelitis by modulating colonic immune cells.
    J Immunol. 2025 Nov 1:vkaf289. doi: 10.1093.
    PubMed     Abstract available


  20. YU R, Kim S, Li S, Yang W, et al
    Intronic miR-342 is a key regulator of cellular glycolysis in Foxp3+ regulatory CD4 T cells.
    J Immunol. 2025;214:2976-2986.
    PubMed     Abstract available


    October 2025
  21. CHURCH ME, Hernandez SI, Alvarez JI
    Neuroinflammatory canine disorders: unveiling disease mechanisms from a One Health perspective.
    J Immunol. 2025;214:2535-2542.
    PubMed     Abstract available


    September 2025
  22. ZIPFEL PF, Heidenreich K
    The 4 functional segments of Factor H: Role in physiological target recognition and contribution to disease.
    J Immunol. 2025;214:2150-2164.
    PubMed     Abstract available


  23. LIU F, Wawersik S, Tomlinson S, Thurman JM, et al
    Tissue-targeted regulators of complement for amelioration of human disease: rationale and novel therapeutic strategies.
    J Immunol. 2025;214:2138-2149.
    PubMed     Abstract available


    August 2025
  24. RACINE JJ, Dwyer JR, Chapman HD, Bell A, et al
    Direct-in-NOD genetic ablation of Bcl3 leads to complete type 1 diabetes protection.
    J Immunol. 2025 Aug 12:vkaf189. doi: 10.1093.
    PubMed     Abstract available


    July 2025
  25. OO TT, Hariharasubramanian A, Pallikonda Chakravarthy S, Singh N, et al
    Age-related decline in HMGB1-neutralizing IgM autoantibody response impairs resistance to high-fat diet in mice.
    J Immunol. 2025 Jul 29:vkaf172. doi: 10.1093.
    PubMed     Abstract available


  26. VDOVENKO D, Stefanska M, Wijnen WJ, Zarak-Crnkovic M, et al
    IL-23 promotes T cell trafficking in experimental autoimmune myocarditis.
    J Immunol. 2025 Jul 21:vkaf150. doi: 10.1093.
    PubMed     Abstract available


    June 2025
  27. JIANG K, Xu Y, Wang Y, Yin N, et al
    Deciphering the role of IL-17D, its newly identified receptor CD93, and IL-17D-CD93 axis in health and disease.
    J Immunol. 2025;214:1113-1122.
    PubMed     Abstract available


  28. ZHEN Y, Shao WH
    WDFY1-expressing follicular dendritic cells play a critical role in lupus development in cGVHD mouse model.
    J Immunol. 2025;214:1160-1172.
    PubMed     Abstract available


    May 2025
  29. CHEN N, Wu J, Sun D, Kaplan HJ, et al
    Mice deficient of G-protein coupled receptor 3 (GPR3) developed severe experimental autoimmune uveitis (EAU) through increased effector T cell activities.
    J Immunol. 2025 May 17:vkaf099. doi: 10.1093.
    PubMed     Abstract available


    April 2025
  30. TURICEK DP, Wan X
    Decoding autoimmunity: HLA-DQbeta and type 1 diabetes.
    J Immunol. 2025 Apr 28:vkaf070. doi: 10.1093.
    PubMed    


  31. ZHENG G, Oo TT, Janjam SSS, Ellis C, et al
    An antigen-less pro-vaccine for treating autoimmunity.
    J Immunol. 2025 Apr 24:vkaf068. doi: 10.1093.
    PubMed     Abstract available


  32. AHN SH, Halgren K, Grzesiak G, MacRenaris KW, et al
    Autoimmune regulator deficiency causes sterile epididymitis and impacts male fertility through disruption of inorganic physiology.
    J Immunol. 2025 Apr 23:vkaf054. doi: 10.1093.
    PubMed     Abstract available


  33. DICILLO EB, Pisetsky DS, Svenungsson E, Diaz-Gallo LM, et al
    Characterization of autoantibody profiles in clusters of systemic lupus erythematosus using a novel autoantigen discovery technology.
    J Immunol. 2025 Apr 3:vkae025. doi: 10.1093.
    PubMed     Abstract available


    March 2025
  34. SUAN D, Moore J, Goodnow CC
    Can autoimmune disease be cured by deep CD19+ cell depletion?
    J Immunol. 2025 Mar 21:vkaf008. doi: 10.1093.
    PubMed     Abstract available


  35. HUI CW, Wu WC, Tong TK, Shiu C, et al
    Discovery of a new anti-gammac antibody in clinical development for the treatment of autoimmune diseases.
    J Immunol. 2025 Mar 12:vkae020. doi: 10.1093.
    PubMed     Abstract available


    January 2025
  36. HIGDON LE, Cooney LA, Serti E, Suwannasaen D, et al
    Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes.
    J Immunol. 2025;214:12-22.
    PubMed     Abstract available


    October 2024
  37. PENG W, Merlo LMF, Grabler S, Montgomery JD, et al
    IDO2 Drives Autoantibody Production and Joint Inflammation in a Preclinical Model of Arthritis by Repressing Runx1 Function in B Cells.
    J Immunol. 2024 Oct 14:ji2400445. doi: 10.4049/jimmunol.2400445.
    PubMed     Abstract available


  38. TAYLOR JP, Blum SI, Graffeo HC, Shang Q, et al
    The Type 1 Diabetes-Associated Single Nucleotide Polymorphism rs1990760 in IFIH1 Is Associated with Increased Basal Type I IFNs and IFN-stimulated Gene Expression.
    J Immunol. 2024 Oct 7:ji2400344. doi: 10.4049/jimmunol.2400344.
    PubMed     Abstract available


  39. LEBER A, Hontecillas R, Tubau-Juni N, Fitch SN, et al
    Immunometabolic Mechanisms of LANCL2 in CD4+ T Cells and Phagocytes Provide Protection from Systemic Lupus Erythematosus.
    J Immunol. 2024 Oct 4:ji2400127. doi: 10.4049/jimmunol.2400127.
    PubMed     Abstract available


    September 2024
  40. ZHONG B, Zhou JQ, Lyu X, Liu H, et al
    Anti-Heat Shock Protein 70 Autoantibodies from Patients with Idiopathic Pulmonary Fibrosis Epigenetically Enhance Lung Fibroblast Apoptosis Resistance and Bcl-2 Expression.
    J Immunol. 2024 Sep 9:ji2400106. doi: 10.4049/jimmunol.2400106.
    PubMed     Abstract available


  41. LIU JQ, Jabbari A, Lin CH, Akkanapally V, et al
    IL-27 Gene Therapy Ameliorates IPEX Syndrome Caused by Germline Mutation of Foxp3 Gene: A Major Role for Induction of IL-10.
    J Immunol. 2024;213:559-566.
    PubMed     Abstract available


    August 2024
  42. BLEVINS LK, Khan DMIO, Crawford RB, O'Neill C, et al
    CD9 and Aryl Hydrocarbon Receptor Are Markers of Human CD19+CD14+ Atypical B Cells and Are Dysregulated in Systemic Lupus Erythematous Disease.
    J Immunol. 2024 Aug 30:ji2400193. doi: 10.4049/jimmunol.2400193.
    PubMed     Abstract available


  43. SANTANA S, Papillion A, Foote JB, Bachus H, et al
    Cutting Edge: Low-dose Recombinant IL-2 Treatment Prevents Autoantibody Responses in Systemic Lupus Erythematosus via Regulatory T Cell-independent Depletion of T Follicular Helper Cells.
    J Immunol. 2024 Aug 28:ji2400264. doi: 10.4049/jimmunol.2400264.
    PubMed     Abstract available


  44. GREBINOSKI S, Pieklo G, Zhang Q, Visperas A, et al
    Regulatory T Cell Insufficiency in Autoimmune Diabetes Is Driven by Selective Loss of Neuropilin-1 on Intraislet Regulatory T Cells.
    J Immunol. 2024 Aug 7:ji2300216. doi: 10.4049/jimmunol.2300216.
    PubMed     Abstract available


  45. ZHANG J, Ji H, Liu M, Zheng M, et al
    Mitochondrial DNA Programs Lactylation of cGAS to Induce IFN Responses in Patients with Systemic Lupus Erythematosus.
    J Immunol. 2024 Aug 2:ji2300758. doi: 10.4049/jimmunol.2300758.
    PubMed     Abstract available


    July 2024
  46. CHIU H, Weinstein KN, Spath S, Hu A, et al
    SKI Regulates Medullary Thymic Epithelial Cell Differentiation to Control Peripheral T Cell Responses in Mice.
    J Immunol. 2024;213:52-62.
    PubMed     Abstract available


  47. PATINO-MARTINEZ E, Nakabo S, Jiang K, Carmona-Rivera C, et al
    The Aconitate Decarboxylase 1/Itaconate Pathway Modulates Immune Dysregulation and Associates with Cardiovascular Disease Markers and Disease Activity in Systemic Lupus Erythematosus.
    J Immunol. 2024 Jul 1:ji2400241. doi: 10.4049/jimmunol.2400241.
    PubMed     Abstract available


    June 2024
  48. VISWANATH V, Mistry S, Cabrera-Ghayouri S, Leang R, et al
    Sustained Alleviation of Autoimmunity by Activating alpha2B-adrenergic Receptors.
    J Immunol. 2024 Jun 28:ji2300893. doi: 10.4049/jimmunol.2300893.
    PubMed     Abstract available


  49. CARBONE F, Colamatteo A, La Rocca C, Lepore MT, et al
    Metabolic Plasticity of Regulatory T Cells in Health and Autoimmunity.
    J Immunol. 2024;212:1859-1866.
    PubMed     Abstract available


  50. VEMULAWADA C, Renavikar PS, Crawford MP, Steward-Tharp S, et al
    Disruption of IFNgamma, GZMB, PRF1, or LYST Results in Reduced Suppressive Function in Human CD8+ T Cells.
    J Immunol. 2024;212:1722-1732.
    PubMed     Abstract available


    May 2024
  51. WON KD, Gil Gonzalez L, Cruz-Leal Y, Pavon Oro A, et al
    Antagonism of the Platelet-Activating Factor Pathway Mitigates Inflammatory Adverse Events Driven by Anti-erythrocyte Antibody Therapy in Mice.
    J Immunol. 2024;212:1531-1539.
    PubMed     Abstract available


  52. DAI YD, Du W, Wang Y, Hu WY, et al
    A Targeted Deep Sequencing Method to Quantify Endogenous Retrovirus Gag Sequence Variants and Open Reading Frames Expressed in Nonobese Diabetic Mice.
    J Immunol. 2024 May 13:ji2300660. doi: 10.4049/jimmunol.2300660.
    PubMed     Abstract available


    April 2024
  53. TAO Q, Chen Y, Liang Q, Shi J, et al
    Puerarin Alleviates Experimental Autoimmune Thyroiditis by Regulating Macrophages.
    J Immunol. 2024 Apr 26:ji2300779. doi: 10.4049/jimmunol.2300779.
    PubMed     Abstract available


  54. LORANT AK, Yoshida AE, Gilbertson EA, Chu T, et al
    Integrin alphavbeta3 Limits Cytokine Production by Plasmacytoid Dendritic Cells and Restricts TLR-Driven Autoimmunity.
    J Immunol. 2024 Apr 12:ji2300290. doi: 10.4049/jimmunol.2300290.
    PubMed     Abstract available


  55. DE GEORGE DJ, Jhala G, Selck C, Trivedi P, et al
    Altering beta Cell Antigen Exposure to Exhausted CD8+ T Cells Prevents Autoimmune Diabetes in Mice.
    J Immunol. 2024 Apr 8:ji2300785. doi: 10.4049/jimmunol.2300785.
    PubMed     Abstract available


  56. FRANK C, Salapa HE, Allen KJH, Levin MC, et al
    Antibody-Mediated Depletion of Autoreactive T Lymphocytes through PD-1 Improves Disease Outcomes and Visualizes T Cell Activation in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2024 Apr 5:ji2300751. doi: 10.4049/jimmunol.2300751.
    PubMed     Abstract available


  57. WU J, Han K, Sack MN
    Targeting NAD+ Metabolism to Modulate Autoimmunity and Inflammation.
    J Immunol. 2024;212:1043-1050.
    PubMed     Abstract available


    March 2024
  58. COSTANZO A, Clarke D, Holt M, Sharma S, et al
    Repositioning the Early Pathology of Type 1 Diabetes to the Extraislet Vasculature.
    J Immunol. 2024 Mar 1:ji2300769. doi: 10.4049/jimmunol.2300769.
    PubMed     Abstract available


    February 2024
  59. KAGOHASHI K, Sasaki Y, Ozawa K, Tsuchiya T, et al
    Role of Signal-Transducing Adaptor Protein-1 for T Cell Activation and Pathogenesis of Autoimmune Demyelination and Airway Inflammation.
    J Immunol. 2024 Feb 5:ji2300202. doi: 10.4049/jimmunol.2300202.
    PubMed     Abstract available


  60. DUAN S, Li Q, Wang F, Kuang W, et al
    Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris.
    J Immunol. 2024;212:375-388.
    PubMed     Abstract available


    January 2024
  61. DAR AA, Ortega Y, Aktas S, Wu K, et al
    CRL4b Inhibition Ameliorates Experimental Autoimmune Encephalomyelitis Progression.
    J Immunol. 2024 Jan 24:ji2300754. doi: 10.4049/jimmunol.2300754.
    PubMed     Abstract available


  62. YANDAMURI SS, Filipek B, Lele N, Cohen I, et al
    A Noncanonical CD56dimCD16dim/- NK Cell Subset Indicative of Prior Cytotoxic Activity Is Elevated in Patients with Autoantibody-Mediated Neurologic Diseases.
    J Immunol. 2024 Jan 22:ji2300015. doi: 10.4049/jimmunol.2300015.
    PubMed     Abstract available


  63. TOMALA J, Cao SD, Spangler JB
    Engineering Anticytokine Antibodies for Immune Modulation.
    J Immunol. 2024;212:225-234.
    PubMed     Abstract available


  64. HAN K, Xu J, Xie F, Crowther J, et al
    Engineering Strategies to Modulate the Gut Microbiome and Immune System.
    J Immunol. 2024;212:208-215.
    PubMed     Abstract available


  65. KLUG N, Burke J, Scott E
    Rational Engineering of Islet Tolerance via Biomaterial-Mediated Immune Modulation.
    J Immunol. 2024;212:216-224.
    PubMed     Abstract available


    December 2023
  66. FLYNN AL, Gans J, Escobedo J, Zhu C, et al
    RGS1 Modulates Autophagic and Metabolic Programs and Is a Critical Mediator of Human Regulatory T Cell Function.
    J Immunol. 2023;211:1656-1668.
    PubMed     Abstract available


    November 2023
  67. SONI C, Makita S, Eichinger A, Serpas L, et al
    Cutting Edge: TLR2 Signaling in B Cells Promotes Autoreactivity to DNA via IL-6 Secretion.
    J Immunol. 2023;211:1475-1480.
    PubMed     Abstract available


  68. LU Y, Chiang J, Zhang R, Roche PA, et al
    TRAF6 and TRAF2/3 Binding Motifs in CD40 Differentially Regulate B Cell Function in T-Dependent Antibody Responses and Dendritic Cell Function in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2023 Nov 3:ji2300607. doi: 10.4049/jimmunol.2300607.
    PubMed     Abstract available


  69. MONSON N, Smith C, Greenberg H, Plumb P, et al
    VH2+ Antigen-Experienced B Cells in the Cerebrospinal Fluid Are Expanded and Enriched in Pediatric Anti-NMDA Receptor Encephalitis.
    J Immunol. 2023;211:1332-1339.
    PubMed     Abstract available


  70. AKBAR I, Tang R, Baillargeon J, Roy AP, et al
    Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2023 Nov 1:ji2300526. doi: 10.4049/jimmunol.2300526.
    PubMed     Abstract available


  71. PELLERIN A, Tan Y, Lu S, Bonegio RG, et al
    Genetic Reduction of IRF5 Expression after Disease Initiation Reduces Disease in a Mouse Lupus Model by Impacting Systemic and End-Organ Pathogenic Pathways.
    J Immunol. 2023;211:1308-1319.
    PubMed     Abstract available


    October 2023
  72. RACINE JJ, Misherghi A, Dwyer JR, Maser R, et al
    HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice.
    J Immunol. 2023 Oct 25:ji2300303. doi: 10.4049/jimmunol.2300303.
    PubMed     Abstract available


  73. SOUKOU-WARGALLA S, Kilian C, Velasquez LN, Machicote A, et al
    Tr1 Cells Emerge and Suppress Effector Th17 Cells in Glomerulonephritis.
    J Immunol. 2023 Oct 18:ji2300305. doi: 10.4049/jimmunol.2300305.
    PubMed     Abstract available


  74. JORDAN TJM, Chen J, Li N, Burette S, et al
    The Eotaxin-1/CCR3 Axis and Matrix Metalloproteinase-9 Are Critical in Anti-NC16A IgE-Induced Bullous Pemphigoid.
    J Immunol. 2023;211:1216-1223.
    PubMed     Abstract available


  75. GILLES A, Hu L, Virdis F, Sant'Angelo DB, et al
    The MHC Class II Antigen-Processing and Presentation Pathway Is Dysregulated in Type 1 Diabetes.
    J Immunol. 2023 Oct 9:ji2300213. doi: 10.4049/jimmunol.2300213.
    PubMed     Abstract available


  76. MOK MY, Luo CY, Huang FP, Kong WY, et al
    IL-33 Orchestrated the Interaction and Immunoregulatory Functions of Alternatively Activated Macrophages and Regulatory T Cells In Vitro.
    J Immunol. 2023;211:1134-1143.
    PubMed     Abstract available


    September 2023
  77. NEW JS, Dizon BLP, King RG, Greenspan NS, et al
    B-1 B Cell-Derived Natural Antibodies against N-Acetyl-d-Glucosamine Suppress Autoimmune Diabetes Pathogenesis.
    J Immunol. 2023 Sep 25:ji2300264. doi: 10.4049/jimmunol.2300264.
    PubMed     Abstract available


  78. MORIN F, Singh N, Mdzomba JB, Dumas A, et al
    Correction: Conditional Deletions of Hdc Confirm Roles of Histamine in Anaphylaxis and Circadian Activity but Not in Autoimmune Encephalomyelitis.
    J Immunol. 2023 Sep 11:ji2300549. doi: 10.4049/jimmunol.2300549.
    PubMed     Abstract available


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