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COVID-19: Daily Top 10 Papers


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4 Allergy
1 Am J Respir Crit Care Med
8 Ann Allergy Asthma Immunol
1 Arch Dis Child
2 Can Respir J
3 Chest
1 Clin Exp Allergy
4 Eur Respir J
3 J Allergy Clin Immunol
5 J Asthma
1 J Immunol
1 J Pediatr
1 Pediatr Pulmonol
1 PLoS Med
1 PLoS One
1 Pulm Pharmacol Ther
2 Respir Res
1 Respiration
2 Respirology
3 Thorax

  Retrieve available abstracts of this week’s articles:
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Single Articles


  1. NIESSEN NM, Gibson PG, Baines KJ, Barker D, et al
    Sputum TNF markers are increased in neutrophilic and severe asthma andarereduced by azithromycin treatment.
    Allergy. 2021 Feb 11. doi: 10.1111/all.14768.
    PubMed         Abstract available

  2. POHLMEIER L, Sonar S, Rodewald HR, Kopf M, et al
    Comparative analysis of the role of mastcells in murine asthma models using Kit-sufficient mast cell-deficient animals.
    Allergy. 2021 Feb 9. doi: 10.1111/all.14765.
    PubMed         Abstract available

  3. CAZZOLA M, Calzetta L, Matera MG
    Long-acting muscarinic antagonists and small airways in asthma: which link?
    Allergy. 2021 Feb 9. doi: 10.1111/all.14766.
    PubMed         Abstract available

  4. ADEL-PATIENT K, Grauso M, Abou-Taam R, Guillon B, et al
    Immune signatures distinguish frequent from non-frequent exacerbators among children with severe asthma.
    Allergy. 2021 Feb 5. doi: 10.1111/all.14759.

    Am J Respir Crit Care Med

  5. HASTIE AT, Mauger DT, Denlinger LC, Coverstone A, et al
    Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program.
    Am J Respir Crit Care Med. 2021 Feb 5. doi: 10.1164/rccm.202009-3713.
    PubMed         Abstract available

    Ann Allergy Asthma Immunol

    Aspirin desensitization vs biologics for patients with aspirin-exacerbated respiratory disease.
    Ann Allergy Asthma Immunol. 2020 Aug 6. pii: S1081-1206(20)30566.

  7. STEVENS WW, Kato A
    Group 2 innate lymphoid cells in nasal polyposis.
    Ann Allergy Asthma Immunol. 2021;126:110-117.
    PubMed         Abstract available

  8. CAVAGNERO KJ, Doherty TA
    Lipid-mediated innate lymphoid cell recruitment and activation in aspirin-exacerbated respiratory disease.
    Ann Allergy Asthma Immunol. 2021;126:135-142.
    PubMed         Abstract available

  9. BUCHHEIT KM, Hulse KE
    Local immunoglobulin production in nasal tissues: A key to pathogenesis in chronic rhinosinusitis with nasal polyps and aspirin-exacerbated respiratory disease.
    Ann Allergy Asthma Immunol. 2021;126:127-134.
    PubMed         Abstract available

  10. MENDOZA J, Quinn J, Infante A, Nath P, et al
    A novel activation-induced cytidine deaminase mutation in an adult with hyper-immunoglobulin M syndrome.
    Ann Allergy Asthma Immunol. 2021;126:199-200.

  11. MARTIN HC, Derakhshan T, Dwyer DF
    Insights into mast cell hyperplasia in aspirin-exacerbated respiratory disease from transcriptional profiling of polyp mast cells.
    Ann Allergy Asthma Immunol. 2021;126:120-121.

  12. LIPWORTH B, RuiWen Kuo C, Jabbal S, Chan R, et al
    Inhaled triple therapy and airway hyperresponsiveness in persistent asthma.
    Ann Allergy Asthma Immunol. 2021 Feb 3. pii: S1081-1206(21)00094.

  13. MOKHALLATI N, Schuler CL, Thomas S, Hossian MM, et al
    Use of the Composite Asthma Severity Index in a Pediatric Subspecialty Clinic.
    Ann Allergy Asthma Immunol. 2021 Feb 4. pii: S1081-1206(21)00098.
    PubMed         Abstract available

    Arch Dis Child

  14. ULDBJERG CS, Miller JE, Burgner D, Pedersen LH, et al
    Antibiotic exposure during pregnancy and childhood asthma: a national birth cohort study investigating timing of exposure and mode of delivery.
    Arch Dis Child. 2021 Feb 9. pii: archdischild-2020-319659.
    PubMed         Abstract available


    Covid-19: People with mild asthma won't get early vaccination.
    BMJ. 2021;372:n430.

    Can Respir J

  16. GUO Y, Zhang X, Liu F, Li L, et al
    Relationship between Poorly Controlled Asthma and Sleep-Related Breathing Disorders in Children with Asthma: A Two-Center Study.
    Can Respir J. 2021;2021:8850382.
    PubMed         Abstract available

  17. LI J, Ye L, She J, Song Y, et al
    Clinical Differences between Early- and Late-Onset Asthma: A Population-Based Cross-Sectional Study.
    Can Respir J. 2021;2021:8886520.
    PubMed         Abstract available


  18. EDDY RL, Parraga G
    Regional Airway Heterogeneity in Asthma: Histopathology, MRI, and CT Imaging.
    Chest. 2021;159:876-877.

  19. MADDUX JT, Inselman JW, Jeffery MM, Lam RW, et al
    Adherence to Asthma Biologics: Implications for Patient Selection, Step Therapy, and Outcomes.
    Chest. 2020 Oct 24. pii: S0012-3692(20)35101-1. doi: 10.1016/j.chest.2020.
    PubMed         Abstract available

  20. KOUCKY V, Uhlik J, Honkova L, Koucky M, et al
    Ventilation Inhomogeneity and Bronchial Basement Membrane Changes in Chronic Neutrophilic Airway Inflammation.
    Chest. 2020;157:779-789.
    PubMed         Abstract available

    Clin Exp Allergy

  21. FUNKE L, Gnipp S, Ahrens M, Eisenacher M, et al
    Quantitative analysis of proteome dynamics in a mouse model of asthma.
    Clin Exp Allergy. 2021 Feb 7. doi: 10.1111/cea.13843.
    PubMed         Abstract available

    Eur Respir J

  22. FERRETTI S, Gelsomino M, Miceli Sopo S
    About the recommendation of the GINA strategy report on asthma step 1.
    Eur Respir J. 2021;57.

    Reply: About the recommendation of the GINA strategy report on asthma step 1.
    Eur Respir J. 2021;57.

  24. WANG R, Alahmadi F, Niven R, Fowler SJ, et al
    Same-day repeatability of fractional exhaled nitric oxide in severe asthma.
    Eur Respir J. 2021 Feb 4. pii: 13993003.03391-2020.

  25. BUSSE WW, Kraft M, Rabe KF, Deniz Y, et al
    Understanding the key issues in the treatment of uncontrolled persistent asthma with type 2 inflammation.
    Eur Respir J. 2021 Feb 4. pii: 13993003.03393-2020.
    PubMed         Abstract available

    J Allergy Clin Immunol

  26. KRINGS JG, Goss CW, Lew D, Samant M, et al
    Quantitative CT metrics are associated with longitudinal lung function decline and future asthma exacerbations: results from SARP-3.
    J Allergy Clin Immunol. 2021 Feb 9. pii: S0091-6749(21)00176.
    PubMed         Abstract available

  27. RAVI A, Goorsenberg AWM, Dijkhuis A, Dierdorp BS, et al
    Metabolic differences between bronchial epithelium from healthy individuals and asthma patients and the effect of bronchial thermoplasty.
    J Allergy Clin Immunol. 2021 Feb 5. pii: S0091-6749(21)00170.
    PubMed         Abstract available

  28. DELGADO-ECKERT E, James A, Meier-Girard D, Kupczyk M, et al
    Lung function fluctuation patterns unveil asthma and COPD phenotypes unrelated to type 2 inflammation.
    J Allergy Clin Immunol. 2021 Feb 3. pii: S0091-6749(21)00162.
    PubMed         Abstract available

    J Asthma

  29. SUNJAYA AP, Allida SM, Di Tanna GL, Jenkins C, et al
    Asthma and risk of infection, hospitalisation, ICU admission and mortality from COVID-19: Systematic review and meta-analysis.
    J Asthma. 2021 Feb 8:1-22. doi: 10.1080/02770903.2021.1888116.
    PubMed         Abstract available

  30. MINDLIS I, Wisnivesky JP, Wolf MS, O'Conor R, et al
    Comorbidity Burden and Depressive Symptoms among Older Adults with Asthma.
    J Asthma. 2021 Feb 8:1-12. doi: 10.1080/02770903.2021.1887890.
    PubMed         Abstract available

  31. ARORA N, Lowe D, Sarsour N, Jaffee H, et al
    Asthma care during COVID-19: Differences in attitudes and expectations between physicians and patients.
    J Asthma. 2021 Feb 8:1-10. doi: 10.1080/02770903.2021.1887214.
    PubMed         Abstract available

  32. SHERIFF F, Agarwal A, Thipse M, Radhakrishnan D, et al
    Hot Spots for Pediatric Asthma Emergency Department Visits in Ottawa, Canada.
    J Asthma. 2021 Feb 10:1-14. doi: 10.1080/02770903.2021.1887891.
    PubMed         Abstract available

  33. SANCHEZ CASTILLO S, Smith L, Diaz Suarez A, Lopez Sanchez GF, et al
    Physical activity behaviour in people with asthma and COPD overlap residing in Spain: A cross-sectional analysis.
    J Asthma. 2021 Feb 10:1-13. doi: 10.1080/02770903.2021.1888977.
    PubMed         Abstract available

    J Immunol

  34. OGDEN HL, Lai Y, Nolin JD, An D, et al
    Secreted Phospholipase A2 Group X Acts as an Adjuvant for Type 2 Inflammation, Leading to an Allergen-Specific Immune Response in the Lung.
    J Immunol. 2020 Apr 27. pii: jimmunol.2000102. doi: 10.4049/jimmunol.2000102.
    PubMed         Abstract available

    J Pediatr

  35. VAN DER LAAN SEI, de Hoog MLA, Nijhof SL, Gehring U, et al
    Mental Wellbeing and General Health in Adolescents with Asthma: The PIAMA Birth Cohort Study.
    J Pediatr. 2021 Feb 3. pii: S0022-3476(21)00108.
    PubMed         Abstract available

    Pediatr Pulmonol

  36. VASCONCELLO-CASTILLO L, Torres-Castro R, Sepulveda-Caceres N, Acosta-Dighero R, et al
    Levels of physical activity in children and adolescents with asthma: A systematic review and meta-analysis.
    Pediatr Pulmonol. 2021 Feb 9. doi: 10.1002/ppul.25293.
    PubMed         Abstract available

    PLoS Med

  37. ALSALLAKH MA, Rodgers SE, Lyons RA, Sheikh A, et al
    Association of socioeconomic deprivation with asthma care, outcomes, and deaths in Wales: A 5-year national linked primary and secondary care cohort study.
    PLoS Med. 2021;18:e1003497.
    PubMed         Abstract available

    PLoS One

  38. RUTTEN B, Young S, Rhedin M, Olsson M, et al
    Eosinophil-derived neurotoxin: A biologically and analytically attractive asthma biomarker.
    PLoS One. 2021;16:e0246627.
    PubMed         Abstract available

    Pulm Pharmacol Ther

  39. CARPAGNANO GE, Scioscia G, Lacedonia D, Stornelli SR, et al
    Treatment response according to small airways disease status: The effects of high-strength extrafine pMDI beclomethasone dipropionate/formoterol fumarate in fixed dose combination in moderate uncontrolled asthmatic patients.
    Pulm Pharmacol Ther. 2020;60:101879.
    PubMed         Abstract available

    Respir Res

  40. KERMANI NZ, Song WJ, Badi Y, Versi A, et al
    Correction to: Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma.
    Respir Res. 2021;22:47.

  41. HU Y, Chen Y, Liu S, Jiang F, et al
    Breastfeeding duration modified the effects of neonatal and familial risk factors on childhood asthma and allergy: a population-based study.
    Respir Res. 2021;22:41.
    PubMed         Abstract available


  42. AIELLO M, Ghirardini M, Marchi L, Frizzelli A, et al
    Air Trapping Is Associated with Heterozygosity for Alpha-1 Antitrypsin Mutations in Patients with Asthma.
    Respiration. 2021 Feb 5:1-10. doi: 10.1159/000513072.
    PubMed         Abstract available


    There is more to severe asthma associated with obesity than inflammation.
    Respirology. 2021 Feb 9. doi: 10.1111/resp.14012.

  44. BUI D, Davis S, Flynn A, Bell R, et al
    Impact of recent catastrophic bushfires on people with asthma in Australia: Health, social and financial burdens.
    Respirology. 2021 Feb 11. doi: 10.1111/resp.14013.


  45. MAHON GM, Koppelman GH, Vonk JM
    Grandmaternal smoking, asthma and lung function in the offspring: the Lifelines cohort study.
    Thorax. 2021 Feb 4. pii: thoraxjnl-2020-215232.
    PubMed         Abstract available

  46. DILASSER F, Rose L, Hassoun D, Klein M, et al
    Essential role of smooth muscle Rac1 in severe asthma-associated airway remodelling.
    Thorax. 2021 Feb 4. pii: thoraxjnl-2020-216271.
    PubMed         Abstract available

  47. LENNEY W
    Task shifting: a common-sense approach in children with asthma?
    Thorax. 2021 Feb 4. pii: thoraxjnl-2020-216695.

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