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Articles published in Cardiovasc Res

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    July 2021
  1. ALVAREZ-FRANCO A, Rouco R, Ramirez RJ, Guerrero-Serna G, et al
    Erratum to: Transcriptome and proteome mapping in the sheep atria reveal molecular features of atrial fibrillation progression.
    Cardiovasc Res. 2021 Jul 13. pii: 6319837. doi: 10.1093.

    June 2021
    From translation to integration: how to approach the complexity of atrial fibrillation mechanisms.
    Cardiovasc Res. 2021;117:e88-e90.

  3. NATTEL S, Lip GYH, Filgueiras-Rama D, Dobrev D, et al
    Challenges and Opportunities in Improving the Management of Atrial Fibrillation: Recent Research Advances and their Clinical Translation.
    Cardiovasc Res. 2021 Jun 4. pii: 6292088. doi: 10.1093.

    May 2021
  4. CASADEI B, Sipido KR
    Calcium and postoperative atrial fibrillation: round up the usual suspects!
    Cardiovasc Res. 2021 May 29. pii: 6288489. doi: 10.1093.

  5. WIEDMANN F, Beyersdorf C, Zhou XB, Kraft M, et al
    Treatment of atrial fibrillation with doxapram: TASK-1 potassium channel inhibition as a novel pharmacological strategy.
    Cardiovasc Res. 2021 May 24. pii: 6283579. doi: 10.1093.
    PubMed     Abstract available

  6. HANNA P, Buch E, Stavrakis S, Meyer C, et al
    Neuroscientific Therapies for Atrial Fibrillation.
    Cardiovasc Res. 2021 May 14. pii: 6275748. doi: 10.1093.
    PubMed     Abstract available

  7. KANY S, Reissmann B, Metzner A, Kirchhof P, et al
    Genetics of atrial fibrillation - practical applications for clinical management: If not now, when and how?
    Cardiovasc Res. 2021 May 12. pii: 6274893. doi: 10.1093.
    PubMed     Abstract available

  8. OLIER I, Ortega-Martorell S, Pieroni M, Lip GYH, et al
    How machine learning is impacting research in atrial fibrillation: Implications for risk prediction and future management.
    Cardiovasc Res. 2021 May 12. pii: 6274894. doi: 10.1093.
    PubMed     Abstract available

    April 2021
  9. HEIJMAN J, Sutanto H, Crijns HJGM, Nattel S, et al
    Computational models of atrial fibrillation: achievements, challenges and perspectives for improving clinical care.
    Cardiovasc Res. 2021 Apr 23. pii: 6247759. doi: 10.1093.
    PubMed     Abstract available

  10. HATEM SN
    Revealing the molecular history of the transition from paroxysmal to permanent atrial fibrillation.
    Cardiovasc Res. 2021 Apr 20. pii: 6241493. doi: 10.1093.

    March 2021
  11. HERRAIZ-MARTINEZ A, Tarifa C, Jimenez-Sabado V, Llach A, et al
    Influence of sex on intracellular calcium homeostasis in patients with atrial fibrillation.
    Cardiovasc Res. 2021 Mar 31. pii: 6206778. doi: 10.1093.
    PubMed     Abstract available

  12. NATTEL S, Sager P, Huser J, Heijman J, et al
    Why translation from basic discoveries to clinical applications is so difficult for atrial fibrillation and possible approaches to improving it.
    Cardiovasc Res. 2021 Mar 25. pii: 6189086. doi: 10.1093.
    PubMed     Abstract available

  13. ZHANG Y, Zhang S, Li B, Luo Y, et al
    Gut microbiota dysbiosis promotes age-related atrial fibrillation by lipopolysaccharide and glucose-induced activation of NLRP3-inflammasome.
    Cardiovasc Res. 2021 Mar 23. pii: 6184135. doi: 10.1093.
    PubMed     Abstract available

  14. SAFABAKHSH S, Panwar P, Barichello S, Sangha SS, et al
    Cardiovasc Res. 2021 Mar 21. pii: 6179316. doi: 10.1093.
    PubMed     Abstract available

  15. QUINTANILLA JG, Shpun S, Jalife J, Filgueiras-Rama D, et al
    Novel approaches to mechanism-based atrial fibrillation ablation.
    Cardiovasc Res. 2021 Mar 21. pii: 6179319. doi: 10.1093.
    PubMed     Abstract available

  16. AGUILAR M, Rose RA, Takawale A, Nattel S, et al
    New aspects of endocrine control of atrial fibrillation and possibilities for clinical translation.
    Cardiovasc Res. 2021 Mar 16. pii: 6173397. doi: 10.1093.
    PubMed     Abstract available

  17. KORNEJ J, Hanger VA, Trinquart L, Ko D, et al
    New biomarkers from multiomics approaches - improving risk prediction of atrial fibrillation.
    Cardiovasc Res. 2021 Mar 5. pii: 6159768. doi: 10.1093.
    PubMed     Abstract available

    February 2021
  18. DITTMANN S, Kayser A, Schulze-Bahr E
    Long, longer, long QT syndrome: what makes the difference?
    Cardiovasc Res. 2021;117:637-639.

  19. LI X, Garcia-Elias A, Benito B, Nattel S, et al
    The effects of cardiac stretch on atrial fibroblasts: Analysis of the evidence and potential role in atrial fibrillation.
    Cardiovasc Res. 2021 Feb 10. pii: 6133258. doi: 10.1093.
    PubMed     Abstract available

  20. NIETO-MARIN P, Tinaquero D, Utrilla RG, Cebrian J, et al
    Tbx5 variants disrupt Nav1.5 function differently in patients diagnosed with Brugada or Long QT Syndrome.
    Cardiovasc Res. 2021 Feb 8. pii: 6130792. doi: 10.1093.
    PubMed     Abstract available

    January 2021
  21. MIGHIU AS, Recalde A, Ziberna K, Carnicer R, et al
    Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice.
    Cardiovasc Res. 2021 Jan 23. pii: 6105183. doi: 10.1093.
    PubMed     Abstract available

  22. DING WY, Protty MB, Davies IG, Lip GYH, et al
    Relationship between lipoproteins, thrombosis and atrial fibrillation.
    Cardiovasc Res. 2021 Jan 23. pii: 6111888. doi: 10.1093.
    PubMed     Abstract available

  23. TOENNIS T, Kirchhof P
    Connecting the dots? Rate control, heart failure, and atrial fibrillation.
    Cardiovasc Res. 2021;117:336-337.

  24. CASADEI B, Wijesurendra R
    Atrial fibrillation after cardiac surgery: to screen or not to screen?
    Cardiovasc Res. 2021 Jan 12. pii: 6091151. doi: 10.1093.

  25. BENZ AP, Healey JS, Chin A, Commerford P, et al
    Stroke risk prediction in patients with atrial fibrillation with and without rheumatic heart disease.
    Cardiovasc Res. 2021 Jan 2. pii: 6059218. doi: 10.1093.
    PubMed     Abstract available

    November 2020
  26. BENTLEY R, Logantha SJRJ, Sharma P, Rainbow RR, et al
    Pathophysiological insights into atrial fibrillation: revisiting electrophysiological substrate, anatomical substrate, and possible insights from proteomics.
    Cardiovasc Res. 2020 Nov 18. pii: 5989794. doi: 10.1093.

  27. VITOLO M, Lip GYH
    Understanding the global burden of atrial fibrillation and regional variations: we need improvement.
    Cardiovasc Res. 2020 Nov 11. pii: 5974204. doi: 10.1093.

    Two sides of the same coin: new insights into mechanisms of ventricular fibrillation.
    Cardiovasc Res. 2020 Nov 6. pii: 5957449. doi: 10.1093.

  29. SCHMIDT C, Bollini S
    ESC Congress 2020, the digital experience: a report from the ESC Scientists of Tomorrow.
    Cardiovasc Res. 2020;116:e190-e192.

    October 2020
  30. ALVAREZ-FRANCO A, Rouco R, Ramirez RJ, Guerrero-Serna G, et al
    Transcriptome and proteome mapping in the sheep atria reveal molecular features of atrial fibrillation progression.
    Cardiovasc Res. 2020 Oct 29. pii: 5942974. doi: 10.1093.
    PubMed     Abstract available

  31. FAKUADE FE, Tomsits P, Voigt N
    Connexin hemichannels in atrial fibrillation - Orphaned and irrelevant?
    Cardiovasc Res. 2020 Oct 28. pii: 5942088. doi: 10.1093.

    September 2020
  32. DING WY, Gupta D, Wong CF, Lip GYH, et al
    Pathophysiology of Atrial Fibrillation and Chronic Kidney Disease.
    Cardiovasc Res. 2020 Sep 1. pii: 5900260. doi: 10.1093.
    PubMed     Abstract available

    August 2020
  33. JOSEPH PG, Healey JS, Raina P, Connolly SJ, et al
    Global variations in the prevalence, treatment, and impact of atrial fibrillation in a multi-national cohort of 153,152 middle-aged individuals.
    Cardiovasc Res. 2020 Aug 10. pii: 5890677. doi: 10.1093.
    PubMed     Abstract available

    July 2020
  34. SCHMIDT C, Ravens U
    Genetic background of atrial fibrillation: influence of single-nucleotide polymorphisms.
    Cardiovasc Res. 2020;116:e106-e108.

  35. PERRY MD, Ng CA, Mangala MM, Ng TYM, et al
    Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization.
    Cardiovasc Res. 2020;116:1434-1445.
    PubMed     Abstract available

  36. LEMME M, Braren I, Prondzynski M, Aksehirlioglu B, et al
    Chronic intermittent tachypacing by an optogenetic approach induces arrhythmia vulnerability in human engineered heart tissue.
    Cardiovasc Res. 2020;116:1487-1499.
    PubMed     Abstract available

  37. SURYAWANSHI H, Clancy R, Morozov P, Halushka MK, et al
    Cell atlas of the foetal human heart and implications for autoimmune-mediated congenital heart block.
    Cardiovasc Res. 2020;116:1446-1457.
    PubMed     Abstract available

    June 2020
  38. TIEU A, Akar FG
    'Social distancing' of the neuronal nitric oxide synthase from its adaptor protein causes arrhythmogenic trigger-substrate interactions in Long QT Syndrome.
    Cardiovasc Res. 2020 Jun 26. pii: 5863265. doi: 10.1093.

  39. ZHANG Y, Qi Y, Li JJ, He WJ, et al
    Stretch-induced sarcoplasmic reticulum calcium leak is causatively associated with atrial fibrillation in pressure-overloaded hearts.
    Cardiovasc Res. 2020 Jun 12. pii: 5856737. doi: 10.1093.
    PubMed     Abstract available

  40. FAKUADE FE, Steckmeister V, Seibertz F, Gronwald J, et al
    Altered Atrial Cytosolic Calcium Handling Contributes to the Development of Postoperative Atrial Fibrillation.
    Cardiovasc Res. 2020 Jun 10. pii: 5855672. doi: 10.1093.
    PubMed     Abstract available

    May 2020
  41. HANDA BS, Li X, Baxan N, Roney C, et al
    Ventricular fibrillation mechanism and global fibrillatory organisation are determined by gap junction coupling and fibrosis pattern.
    Cardiovasc Res. 2020 May 13. pii: 5836828. doi: 10.1093.
    PubMed     Abstract available

  42. CHEEDIPUDI SM, Hu J, Fan S, Yuan P, et al
    Exercise restores dysregulated gene expression in a mouse model of arrhythmogenic cardiomyopathy.
    Cardiovasc Res. 2020;116:1199-1213.
    PubMed     Abstract available

    March 2020
  43. LEE YK, Sala L, Mura M, Rocchetti M, et al
    MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes.
    Cardiovasc Res. 2020 Mar 16. pii: 5804882. doi: 10.1093.
    PubMed     Abstract available

  44. TSAI SY, Ghazizadeh Z, Wang HJ, Amin S, et al
    A human embryonic stem cell reporter line for monitoring chemical-induced cardiotoxicity.
    Cardiovasc Res. 2020;116:658-670.
    PubMed     Abstract available

    January 2020
  45. ZHANG D, Tu H, Wang C, Cao L, et al
    Inhibition of N-type calcium channels in cardiac sympathetic neurons attenuates ventricular arrhythmogenesis in heart failure.
    Cardiovasc Res. 2020 Jan 29. pii: 5717428. doi: 10.1093.
    PubMed     Abstract available

  46. GUICHARD JB, Xiong F, Qi XY, L'Heureux N, et al
    Role of atrial arrhythmia and ventricular response in atrial fibrillation induced atrial remodeling.
    Cardiovasc Res. 2020 Jan 24. pii: 5715577. doi: 10.1093.
    PubMed     Abstract available

  47. PATEL J, Bezzina CR
    Scientists on the Spot: The complex inheritance of cardiac disorders.
    Cardiovasc Res. 2020;116:e11.

    December 2019
  48. GRANDI E, Dobrev D
    Atrial fibrillation in a dish: Insights into atrial arrhythmogenesis from induced pluripotent stem cell derived cardiomyocytes.
    Cardiovasc Res. 2019 Dec 20. pii: 5682408. doi: 10.1093.

    November 2019
  49. PFENNIGER A, Arora R
    Beyond beta-blockers: targeting the sympathetic nervous system for the prevention and treatment of atrial fibrillation.
    Cardiovasc Res. 2019 Nov 5. pii: 5613161. doi: 10.1093.

    August 2019
  50. BENZONI P, Campostrini G, Landi S, Bertini V, et al
    Human iPSC modeling of a familial form of atrial fibrillation reveals a gain of function of If and ICaL in patient-derived cardiomyocytes.
    Cardiovasc Res. 2019 Aug 28. pii: 5555813. doi: 10.1093.
    PubMed     Abstract available

    May 2019
  51. TAJIRI K, Guichard JB, Qi X, Xiong F, et al
    An N-/L-Type Calcium Channel Blocker, Cilnidipine, Suppresses Autonomic, Electrical and Structural Remodeling Associated with Atrial Fibrillation.
    Cardiovasc Res. 2019 May 22. pii: 5497484. doi: 10.1093.
    PubMed     Abstract available

  52. NATTEL S
    Computational models of the atrial fibrillation substrate: can they explain post-ablation recurrences and help to prevent them.
    Cardiovasc Res. 2019 May 14. pii: 5488996. doi: 10.1093.

  53. FERRANTINI C, Coppini R, Sacconi L
    Cardiomyocyte-specific Gq signalling and arrhythmias: novel insights from DREADD technology.
    Cardiovasc Res. 2019;115:992-994.

    March 2019
  54. HOFFMAN JA, Arora R
    Arrhythmogenic cardiomyopathy: in search of unifying genetic theory.
    Cardiovasc Res. 2019;115:691-692.

    Menage a trois: single-nucleotide polymorphisms, calcium and atrial fibrillation.
    Cardiovasc Res. 2019;115:479-481.

  56. DIETRICHS ES, Tveita T, Smith G
    Hypothermia and cardiac electrophysiology: a systematic review of clinical and experimental data.
    Cardiovasc Res. 2019;115:501-509.
    PubMed     Abstract available

  57. VALVERDE CA, Mazzocchi G, Di Carlo MN, Ciocci Pardo A, et al
    Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors.
    Cardiovasc Res. 2019;115:556-569.
    PubMed     Abstract available

    January 2019
  58. SURINKAEW S, Aflaki M, Takawale A, Chen Y, et al
    Exchange protein activated by cyclic-adenosine monophosphate (Epac) regulates atrial fibroblast function and controls cardiac remodelling.
    Cardiovasc Res. 2019;115:94-106.
    PubMed     Abstract available

  59. KONDO H, Kira S, Oniki T, Gotoh K, et al
    Interleukin-10 treatment attenuates sinus node dysfunction caused by streptozotocin-induced hyperglycaemia in mice.
    Cardiovasc Res. 2019;115:57-70.
    PubMed     Abstract available

    November 2018
  60. NATTEL S
    Natriuretic Protein Receptors and Atrial Selective Fibrosis: Potential Role in Atrial Fibrillation.
    Cardiovasc Res. 2018 Nov 21. pii: 5194685. doi: 10.1093.

  61. KHAN AA, Lip GYH
    The prothrombotic state in atrial fibrillation: pathophysiological and management implications.
    Cardiovasc Res. 2018 Nov 2. pii: 5156062. doi: 10.1093.
    PubMed     Abstract available

    September 2018
  62. RAHMUTULA D, Zhang H, Wilson EE, Olgin JE, et al
    Absence of NPR-C Attenuates TGF-ss1 Induced Selective Atrial Fibrosis and Atrial Fibrillation.
    Cardiovasc Res. 2018 Sep 18. pii: 5100876. doi: 10.1093.
    PubMed     Abstract available

    August 2018
  63. COPPINI R, Ferrantini C
    NaV1.8: a novel contributor to cardiac arrhythmogenesis in heart failure.
    Cardiovasc Res. 2018 Aug 29. pii: 5086354. doi: 10.1093.

  64. HERRAIZ-MARTINEZ A, Llach A, Tarifa C, Gandia J, et al
    The 4q25 variant rs13143308T links risk of atrial fibrillation to defective calcium homeostasis.
    Cardiovasc Res. 2018 Aug 14. pii: 5096929. doi: 10.1093.
    PubMed     Abstract available

    July 2018
  65. VOIGT N, Nattel S
    Prof Niels Voigt talks to Prof Stanley Nattel about advances in atrial fibrillation research and career insights.
    Cardiovasc Res. 2018;114:e65.

    June 2018
  66. NATTEL S
    Catheter ablation of atrial fibrillation and outcomes in heart failure patients: seeking the treasure in the CASTLE.
    Cardiovasc Res. 2018;114:e50-e52.

    April 2018
  67. DRIES E, Santiago DJ, Gilbert G, Lenaerts I, et al
    Hyperactive ryanodine receptors in human heart failure and ischemic cardiomyopathy reside outside of couplons.
    Cardiovasc Res. 2018 Apr 14. pii: 4970798. doi: 10.1093.
    PubMed     Abstract available

  68. BORGOGNONE A, Shantsila E, Worrall SM, Prompunt E, et al
    Nitrite circumvents platelet resistance to nitric oxide in patients with heart failure preserved ejection fraction and chronic atrial fibrillation.
    Cardiovasc Res. 2018 Apr 12. pii: 4969512. doi: 10.1093.
    PubMed     Abstract available

  69. BARICHELLO S, Roberts JD, Backx P, Boyle P, et al
    Personalizing Therapy for Atrial Fibrillation: the Role of Stem Cell and in Silico Disease Models.
    Cardiovasc Res. 2018 Apr 10. pii: 4966930. doi: 10.1093.
    PubMed     Abstract available

    February 2018
  70. DOBREV D, Lorenz K
    Age-dependent Increase in JNK2 Activity: Does This Help to Understand CaMKII-mediated Atrial Arrhythmogenesis in Human Atrial Fibrillation?
    Cardiovasc Res. 2018 Feb 8. pii: 4844871. doi: 10.1093.

    December 2017
  71. BRUEGMANN T, Beiert T, Vogt CC, Schrickel JW, et al
    Optogenetic termination of atrial fibrillation in mice.
    Cardiovasc Res. 2017 Dec 23. pii: 4774318. doi: 10.1093.
    PubMed     Abstract available

    October 2017
  72. WESTERHOF BE, Saouti N, van der Laarse WJ, Westerhof N, et al
    Treatment strategies for the right heart in pulmonary hypertension.
    Cardiovasc Res. 2017;113:1465-1473.
    PubMed     Abstract available

    June 2017
  73. PORTERO V, Casini S, Hoekstra M, Verkerk AO, et al
    Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 in murine Scn5a-1798insD+/- and human SCN5A-1795insD+/- iPSC-derived cardiomyocytes.
    Cardiovasc Res. 2017;113:829-838.
    PubMed     Abstract available

  74. SHATTOCK MJ, Park KC, Yang HY, Lee AWC, et al
    Restitution slope is principally determined by steady-state action potential duration.
    Cardiovasc Res. 2017;113:817-828.
    PubMed     Abstract available

    May 2017

  75. Corrigendum to: Multilevel analyses of SCN5A mutations in arrhythmogenic right ventricular dysplasia/cardiomyopathy suggest non-canonical mechanisms for disease pathogenesis.
    Cardiovasc Res. 2017;113:691.

    April 2017
    Ablation outperforming antiarrhythmic drugs need for more research.
    Cardiovasc Res. 2017;113:e4-e5.

  77. DERANGEON M, Montnach J, Cerpa CO, Jagu B, et al
    Transforming growth factor beta receptor inhibition prevents ventricular fibrosis in a mouse model of progressive cardiac conduction disease.
    Cardiovasc Res. 2017;113:464-474.
    PubMed     Abstract available

    March 2017
  78. WATANABE M, Feola I, Majumder R, Jangsangthong W, et al
    Optogenetic manipulation of anatomical re-entry by light-guided generation of a reversible local conduction block.
    Cardiovasc Res. 2017;113:354-366.
    PubMed     Abstract available

  79. KIM TY, Terentyeva R, Roder KH, Li W, et al
    SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR.
    Cardiovasc Res. 2017;113:343-353.
    PubMed     Abstract available

  80. ZHAO YT, Guo YB, Gu L, Fan XX, et al
    Sensitized signalling between L-type Ca2+ channels and ryanodine receptors in the absence or inhibition of FKBP12.6 in cardiomyocytes.
    Cardiovasc Res. 2017;113:332-342.
    PubMed     Abstract available

  81. VERMIJ SH, Abriel H, van Veen TA
    Refining the molecular organization of the cardiac intercalated disc.
    Cardiovasc Res. 2017;113:259-275.
    PubMed     Abstract available

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