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  Alzheimer's Disease

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Articles published in Neuroscience

Retrieve available abstracts of 87 articles:
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Single Articles


    September 2025
  1. CHAUHAN P, Vadia N, Ballal S, Joshi KK, et al
    Decoding the neuroprotective potential of hesperidin: Insights into Alzheimer's disease.
    Neuroscience. 2025 Sep 20:S0306-4522(25)00954.
    PubMed     Abstract available


  2. ALSHEHRI ZS
    Integrating artificial intelligence with small molecule therapeutics and precision medicine for neurochemical understanding of Alzheimer's diseases.
    Neuroscience. 2025;586:44-57.
    PubMed     Abstract available


  3. IQBAL A, Iqbal K, Shah YA, Ullah F, et al
    Multi-filter stacking in inception V3 for enhanced Alzheimer's severity classification.
    Neuroscience. 2025;586:21-31.
    PubMed     Abstract available


  4. ELENI I, Theofanis V, Zisis B, Eleni S, et al
    A review of the TGF-beta1 pathway in Alzheimer's disease and depression: Possible restoration potential of antidepressants.
    Neuroscience. 2025 Sep 12:S0306-4522(25)00925.
    PubMed     Abstract available


  5. SHENG J, Wang J, Zhang Q, Huang R, et al
    Cognitive prediction using regional connectivities and network biomarkers in Alzheimer's disease.
    Neuroscience. 2025 Sep 3:S0306-4522(25)00907.
    PubMed     Abstract available


  6. AKAN T, Akan S, Alp S, Ledbetter CR, et al
    AlzFormer: Video-based space-time attention model for early diagnosis of Alzheimer's disease.
    Neuroscience. 2025 Sep 3:S0306-4522(25)00910.
    PubMed     Abstract available


  7. LAYAL H, Rajbongshi J, Kumar R, Pandey S, et al
    Hydrogen sulfide in the brain as a silent neuroprotector in Alzheimer's disease.
    Neuroscience. 2025 Sep 2:S0306-4522(25)00905.
    PubMed     Abstract available


    August 2025
  8. BARROSO DE SOUSA D, Clara Ribeiro Zucato HM, Ribeiro HM, Alexandre-Silva V, et al
    Interplay between depressive symptoms and Alzheimer's disease dementia: unraveling the potential roles of ADAM10 and Negr1.
    Neuroscience. 2025 Aug 12:S0306-4522(25)00848.
    PubMed     Abstract available


  9. YANG Y, Ji Q, Cao JJ, Zhang YJ, et al
    Overactivation of the inward rectifier K(+) channel 2.1 modulates intrinsic excitability of adult-born granule cells in the male Alzheimer's APP/PS1 mouse model.
    Neuroscience. 2025 Aug 9:S0306-4522(25)00845.
    PubMed     Abstract available


    July 2025
  10. XU Y, Zhang Z, Peng J, Li X, et al
    Use of magnetic resonance structural imaging to identify disease progression in patients with mild cognitive impairment: A voxel-based morphometry and surface-based morphometry study.
    Neuroscience. 2025;579:382-389.
    PubMed     Abstract available


  11. NI L, Lin L, Zhao W, Li Y, et al
    Differences in patterns of functional and structural connectivity alterations of hippocampal subregions in patients on the Alzheimer's disease spectrum.
    Neuroscience. 2025 Jul 19:S0306-4522(25)00807.
    PubMed     Abstract available


  12. AVILA J, Hernandez F, Perry G
    Amyloid and tau pathologies cross-talk to promote Alzheimers disease: novel mechanistic insights.
    Neuroscience. 2025;582:58-62.
    PubMed     Abstract available


  13. KANG X, Tian J, Shu Q, Cheng T, et al
    Microglia-neuron crosstalk in Alzheimer's disease: an exploration of molecular mechanisms and pathological implications.
    Neuroscience. 2025 Jul 10:S0306-4522(25)00781.
    PubMed     Abstract available


  14. NASIRI H, Azargoonjahromi A
    Response to "Reevaluating leucine's effects on Alzheimer's disease: evidence of potential benefits overlooked".
    Neuroscience. 2025 Jul 5:S0306-4522(25)00768.
    PubMed    


    June 2025
  15. WANG G, Ma T, Liu R, Gu H, et al
    Comparisons of metabolites and gut microbiota profiles for both young and middle-aged APPSwe/PS1De9 mice.
    Neuroscience. 2025;577:54-63.
    PubMed     Abstract available


  16. SATHIAN B, Iqbal J, Al Hamad H
    Reevaluating Leucine's effects on Alzheimer's disease: evidence of potential benefits overlooked.
    Neuroscience. 2025;579:121.
    PubMed    


    May 2025
  17. YANG Q, Huang D, Zhang Z, Gao H, et al
    Diabetes affects AD through plasma Abeta40: A Mendelian randomization study.
    Neuroscience. 2025;575:131-139.
    PubMed     Abstract available


  18. NASIRI H, Azargoonjahromi A, Nouri Z, Azimi SM, et al
    Elevated serum leucine levels are associated with cognitive impairment and reduced gray matter and cerebral volume across the Alzheimer's disease continuum.
    Neuroscience. 2025;577:47-53.
    PubMed     Abstract available


  19. AATHIRA NS, Kaur A, Kumar A, Dar GM, et al
    The genetic risk factors, molecular pathways, microRNAs, and the gut microbiome in Alzheimer's disease.
    Neuroscience. 2025 May 13:S0306-4522(25)00373.
    PubMed     Abstract available


  20. GALAL A, Moustafa A, Salama M
    Transforming neurodegenerative disorder care with machine learning: Strategies and applications.
    Neuroscience. 2025;573:272-285.
    PubMed     Abstract available


  21. MORAIS RF, Pires R, Jesus T, Lemos R, et al
    Cognitive impairment in neurodegenerative diseases: A trans-diagnostic approach using a lesion-symptom mapping analysis.
    Neuroscience. 2025;573:214-227.
    PubMed     Abstract available


    April 2025
  22. ZHANG R, Sheng J, Zhang Q, Wang J, et al
    A review of multimodal fusion-based deep learning for Alzheimer's disease.
    Neuroscience. 2025;576:80-95.
    PubMed     Abstract available


  23. JAIN S, Srivastava R
    Enhanced EEG-based Alzheimer's disease detection using synchrosqueezing transform and deep transfer learning.
    Neuroscience. 2025;576:105-117.
    PubMed     Abstract available


  24. JOLIVALT CG, Calcutt NA, Masliah E
    Corrigendum to "Similar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease" [Neuroscience 202 (2012) 405-412].
    Neuroscience. 2025;575:94.
    PubMed    


  25. ROY KK, Mehta DK, Das R
    Reevaluating Alzheimer's disease treatment: Can phytochemicals bridge the therapeutic Gap?
    Neuroscience. 2025;575:1-18.
    PubMed     Abstract available


  26. KHANDAYATARAY P, Murthy MK
    Exploring the nexus: Sleep disorders, circadian dysregulation, and Alzheimer's disease.
    Neuroscience. 2025;574:21-41.
    PubMed     Abstract available


  27. KAUR A, Aran KR
    Unraveling the cGAS-STING pathway in Alzheimer's disease: A new Frontier in neuroinflammation and therapeutic strategies.
    Neuroscience. 2025;573:430-441.
    PubMed     Abstract available


    March 2025
  28. SHAH FA, Qadir H, Khan JZ, Faheem M, et al
    A review: From old drugs to new solutions: The role of repositioning in alzheimer's disease treatment.
    Neuroscience. 2025 Mar 29:S0306-4522(25)00266.
    PubMed     Abstract available


  29. LAU F, Binacchi R, Brugnara S, Cumplido-Mayoral A, et al
    Using Single-Cell RNA sequencing with Drosophila, Zebrafish, and mouse models for studying Alzheimer's and Parkinson's disease.
    Neuroscience. 2025 Mar 26:S0306-4522(25)00244.
    PubMed     Abstract available


  30. CHEN J, Xu S, Wang L, Liu X, et al
    Refining the interactions between microglia and astrocytes in Alzheimer's disease pathology.
    Neuroscience. 2025;573:183-197.
    PubMed     Abstract available


  31. LI Y, Yang C, Liu X, Shu J, et al
    Potential therapeutic targets for Alzheimer's disease: Fibroblast growth factors and their regulation of ferroptosis, pyroptosis and autophagy.
    Neuroscience. 2025;573:42-51.
    PubMed     Abstract available


  32. YAN X, Wang E, Zhao M, Ma G, et al
    Microbial infection instigates tau-related pathology in Alzheimer's disease via activating neuroimmune cGAS-STING pathway.
    Neuroscience. 2025;572:122-133.
    PubMed     Abstract available


    February 2025
  33. WU M, Zhang R, Fu P, Mei Y, et al
    Disrupted astrocyte-neuron signaling reshapes brain activity in epilepsy and Alzheimer's disease.
    Neuroscience. 2025;570:132-151.
    PubMed     Abstract available


  34. KALRA P, Grewal AK, Khan H, Singh TG, et al
    Unscrambling the cellular and molecular threads of Neuroplasticity: Insights into Alzheimer's disease pathogenesis.
    Neuroscience. 2025 Feb 17:S0306-4522(25)00151.
    PubMed     Abstract available


    January 2025
  35. YU Y, Shen H, Qin Q, Wang J, et al
    The investigation of peripheral inflammatory and oxidative stress biomarkers in dementia with Lewy Bodies, compared with Alzheimer's Disease, and mild cognitive impairment.
    Neuroscience. 2025 Jan 10:S0306-4522(24)00764.
    PubMed     Abstract available


    December 2024
  36. WANG ZJ, Han WN, Chai SF, Li Y, et al
    Semaglutide promotes the transition of microglia from M1 to M2 type to reduce brain inflammation in APP/PS1/tau mice.
    Neuroscience. 2024;563:222-234.
    PubMed     Abstract available


  37. WOOD OWG, Yeung JHY, Palpagama TH, Turner C, et al
    Upregulated excitatory amino acid transporter 1 (EAAT1) expression in the human medial temporal lobe in Alzheimer's disease.
    Neuroscience. 2024 Dec 16:S0306-4522(24)00734.
    PubMed     Abstract available


  38. APARAJITA A, Jain U, Srivastava P
    "Current and emerging drug therapies in Alzheimer's disease: A pathophysiological Perspective".
    Neuroscience. 2024;565:499-518.
    PubMed     Abstract available


  39. FANG H, Tian H, Liu J, Peng T, et al
    Ginsenoside Rg1 attenuates Abeta(1-42)-induced microglial cell apoptosis and inflammation in Alzheimer's disease via the GATA4/PDE4A/PI3K/AKT axis.
    Neuroscience. 2024;565:377-385.
    PubMed     Abstract available


  40. LI C, Wang S, Xia Y, Shi F, et al
    Risk factors and predictive models in the progression from MCI to Alzheimer's disease.
    Neuroscience. 2024;565:312-319.
    PubMed     Abstract available


    November 2024
  41. MOHAMMAD HOSSEINI A, Khaleghzadeh-Ahangar H, Rahimi A
    The immunomodulatory effects of psychedelics in Alzheimer's disease-related dementia.
    Neuroscience. 2024 Nov 25:S0306-4522(24)00651.
    PubMed     Abstract available


  42. ZHENG Y, Yu X, Li W, Wu F, et al
    HLA is a potent immunoinflammatory target in asymptomatic Alzheimer's disease.
    Neuroscience. 2024 Nov 19:S0306-4522(24)00638.
    PubMed     Abstract available


  43. CAO W, Zhu B, Liu Z, Jia X, et al
    Comparison of the efficacy of updated drugs for the treatment on the improvement of cognitive function in patients with Alzheimer 's disease: A systematic review and network meta- analysis.
    Neuroscience. 2024 Nov 14:S0306-4522(24)00611.
    PubMed     Abstract available


  44. KHANDAYATARAY P, Murthy MK
    Dietary interventions in mitigating the impact of environmental pollutants on Alzheimer's disease - A review.
    Neuroscience. 2024 Nov 12:S0306-4522(24)00602.
    PubMed     Abstract available


  45. YUAN J, Dong X, Zhou S, Nao J, et al
    Pharmacological activities and therapeutic potential of Hyperoside in the treatment of Alzheimer's and Parkinson's diseases: A systemic review.
    Neuroscience. 2024 Nov 1:S0306-4522(24)00565.
    PubMed     Abstract available


    October 2024
  46. SCARPA JR, Mincer JS
    Chronic pain-induced methylation in the prefrontal cortex targets gene networks associated with cognition and Alzheimer's disease.
    Neuroscience. 2024 Oct 15:S0306-4522(24)00519.
    PubMed     Abstract available


  47. ZHOU J, Gong L, Liu X, Chen L, et al
    Mendelian randomization in Alzheimer's disease and mild cognitive impairment: Hippocampal volume associations.
    Neuroscience. 2024 Oct 3:S0306-4522(24)00510.
    PubMed     Abstract available


  48. SINGH R, Joshi A, Koundal M, Sabharwal A, et al
    Proteomic insights into early-stage Alzheimer's disease: Identifying key neuronal proteins impacted by amyloid beta oligomers in an in vitro model.
    Neuroscience. 2024 Oct 1:S0306-4522(24)00503.
    PubMed     Abstract available


    August 2024
  49. GUTIERREZ RICO E, Joseph P, Noutsos C, Poon K, et al
    Hypothalamic and hippocampal transcriptome changes in App(NL-G-F) mice as a function of metabolic and inflammatory dysfunction.
    Neuroscience. 2024;554:107-117.
    PubMed     Abstract available


  50. SOHN E, Lim HS, Jin Kim Y, Kim BY, et al
    Exploring the therapeutic potential of Potentilla fragarioides var. major (Rosaceae) extract in Alzheimer's disease using in vitro and in vivo models: a multi-faceted approach.
    Neuroscience. 2024 Aug 21:S0306-4522(24)00427.
    PubMed     Abstract available


  51. E R SIMMATIS L, Russo EE, Altug Y, Murugathas V, et al
    Towards discovery and implementation of neurophysiologic biomarkers of Alzheimer's disease using entropy methods.
    Neuroscience. 2024 Aug 18:S0306-4522(24)00403.
    PubMed     Abstract available


  52. CHEN J, Peng G, Sun B
    Alzheimer's disease and sleep disorders: A bidirectional relationship.
    Neuroscience. 2024;557:12-23.
    PubMed     Abstract available


    July 2024
  53. XIANG LY, Chen XY, Lu LM, Kong MH, et al
    Mechanisms of Neuronal Reactivation in Memory Consolidation: A Perspective from Pathological Conditions.
    Neuroscience. 2024;551:196-204.
    PubMed     Abstract available


  54. BHATT A, Bhardwaj H, Shrivastava P
    Mesenchymal stem cell therapy for Alzheimer's disease: A novel therapeutic approach for neurodegenerative diseases.
    Neuroscience. 2024 Jul 18:S0306-4522(24)00332.
    PubMed     Abstract available


    June 2024
  55. AHMAD RATHER M, Khan A, Jahan S, Jamal Siddiqui A, et al
    Influence of Tau on neurotoxicity and cerebral vasculature impairment associated with Alzheimer's disease.
    Neuroscience. 2024 Jun 11:S0306-4522(24)00252.
    PubMed     Abstract available


    April 2024
  56. DENG J, Liu B, Tao Q, Luo Y, et al
    The co-oligomers of Abeta42 and human islet amyloid polypeptide exacerbate neurotoxicity and Alzheimer-like pathology at cellular level.
    Neuroscience. 2024 Apr 9:S0306-4522(24)00155.
    PubMed     Abstract available


    March 2024
  57. W G WOOD O, Walby J, Yeung JH, Ke S, et al
    Alzheimer's disease-associated region-specific decrease of vesicular glutamate transporter immunoreactivity inthe medial temporal lobe and superior temporal gyrus.
    Neuroscience. 2024 Mar 27:S0306-4522(24)00140.
    PubMed     Abstract available


  58. MEHMOOD A, Shahid F, Khan R, Ibrahim MM, et al
    Utilizing Siamese 4D-AlzNet and Transfer Learning to Identify Stages of Alzheimer's Disease.
    Neuroscience. 2024 Mar 14:S0306-4522(24)00112.
    PubMed     Abstract available


    February 2024
  59. XU M, Lin R, Wen H, Wang Y, et al
    Electroacupuncture Enhances the Functional Connectivity of Limbic System to Neocortex in the 5xFAD Mouse Model of Alzheimer's Disease.
    Neuroscience. 2024 Feb 27:S0306-4522(24)00090.
    PubMed     Abstract available


  60. ZHANG H, Yang Y, Zhang J, Huang L, et al
    Oligodendrocytes Play a Critical Role in White Matter Damage of Vascular Dementia.
    Neuroscience. 2024;538:1-10.
    PubMed     Abstract available


    January 2024
  61. QIAO Y, Liu H, He C, Ma Y, et al
    ApoE Mimic Peptide COG1410 Reduces Abeta Deposition and Improves Cognitive Function by Inducing the Transformation of A1/A2 Reactive Astrocytes and Increasing the BDNF Concentration in Brain of APP/PS1 Double Transgenic Mice.
    Neuroscience. 2024;537:116-125.
    PubMed     Abstract available


  62. ALIASHRAFI M, Nasehi M, Zarrindast MR, Joghataei MT, et al
    Intracerebroventricular Cutibacterium acnes generates manifestations of Alzheimer's disease-like pathology in the rat hippocampus.
    Neuroscience. 2024 Jan 22:S0306-4522(24)00023.
    PubMed     Abstract available


    November 2023
  63. WANG Q, Guo S, Hu D, Dong X, et al
    Enhanced GSDME-mediated pyroptosis in Alzheimer's disease.
    Neuroscience. 2023 Nov 7:S0306-4522(23)00491.
    PubMed     Abstract available


    September 2023
  64. ELDEEN MAKKI B, Rahman S
    Erratum to "Alzheimer's Disease in Diabetic Patients: A Lipidomic Prospect" [Neuroscience 530 (2023) 79-94].
    Neuroscience. 2023 Sep 26:S0306-4522(23)00427.
    PubMed    


  65. LIU S, Zheng Y, Li H, Pan M, et al
    Improving Alzheimer Diagnoses with an interpretable Deep Learning Framework: including Neuropsychiatric Symptoms.
    Neuroscience. 2023 Sep 12:S0306-4522(23)00411.
    PubMed     Abstract available


    August 2023
  66. ELDEEN MAKKI B, Rahman S
    Alzheimer's Disease in Diabetic Patients: A Lipidomic Prospect.
    Neuroscience. 2023 Aug 29:S0306-4522(23)00402.
    PubMed     Abstract available


  67. WANG L, Wei Y, Sun Z, Jiang LH, et al
    DpdtpA, A Multi-metal Ion Chelator, Attenuates Tau Phosphorylation and Microglial Inflammatory Response via Regulating the PI3K/AKT/GSK-3beta Signal Pathways.
    Neuroscience. 2023;526:196-203.
    PubMed     Abstract available


  68. LIN LL, Song GJ, Zhang H, Yin Y, et al
    GPR34 knockdown relieves cognitive deficits and suppresses neuroinflammation in Alzheimer's disease via the ERK/NF-kappaB signal.
    Neuroscience. 2023 Aug 7:S0306-4522(23)00342.
    PubMed     Abstract available


  69. YANG P, Liao C, Hu Q, Zhang J, et al
    Benzene, 1,2,4-Trimethoxy-5-(2-Methyl-1-Propen-1-yl) Attenuates D-galactose/AlCl(3)-induced Cognitive Impairment by Inhibiting Inflammation, Apoptosis, and improving Expression of Memory-Related Proteins.
    Neuroscience. 2023;524:242-255.
    PubMed     Abstract available


    June 2023
  70. WANG H, Zhang Z, Sittirattanayeungyong S, Hongpaisan J, et al
    ApoE4-related microvascular disease in the Alzheimer's disease hippocampal CA1 stratum radiatum.
    Neuroscience. 2023 Jun 27:S0306-4522(23)00289.
    PubMed     Abstract available


  71. GUNAWARDENA R, Sarrigiannis PG, Blackburn DJ, He F, et al
    Kernel-based Nonlinear Manifold Learning for EEG-based Functional Connectivity Analysis and Channel Selection with Application to Alzheimer's Disease.
    Neuroscience. 2023 Jun 8:S0306-4522(23)00253.
    PubMed     Abstract available


  72. LI Y, Fan H, Ni M, Zhang W, et al
    Targeting lncRNA NEAT1 hampers Alzheimer's disease progression.
    Neuroscience. 2023 Jun 5:S0306-4522(23)00103.
    PubMed     Abstract available


  73. FROST J, Schmitzer B, Topperwien M, Eckermann M, et al
    3d Virtual Histology Reveals Pathological Alterations of Cerebellar Granule Cells in Multiple Sclerosis.
    Neuroscience. 2023;520:18-38.
    PubMed     Abstract available


    May 2023
  74. MOLINERO N, Anton-Fernandez A, Hernandez F, Avila J, et al
    Gut Microbiota, an Additional Hallmark of Human Aging and Neurodegeneration.
    Neuroscience. 2023;518:141-161.
    PubMed     Abstract available


  75. FOUREST-LIEUVIN A, Vinit A, Blot B, Perrot A, et al
    Controlled Tau Cleavage in Cells Reveals Abnormal Localizations of Tau Fragments.
    Neuroscience. 2023;518:162-177.
    PubMed     Abstract available


  76. GALLO D, Ruiz A, Sanchez-Juan P
    Genetic Architecture of Primary Tauopathies.
    Neuroscience. 2023;518:27-37.
    PubMed     Abstract available


  77. JIMENEZ JS
    Macromolecular Structures and Proteins Interacting with the Microtubule Associated Tau Protein.
    Neuroscience. 2023;518:70-82.
    PubMed     Abstract available


  78. SCHULZ L, Ramirez P, Lemieux A, Gonzalez E, et al
    Tau-Induced Elevation of the Activity-Regulated Cytoskeleton Associated Protein Arc1 Causally Mediates Neurodegeneration in the Adult Drosophila Brain.
    Neuroscience. 2023;518:101-111.
    PubMed     Abstract available


  79. BERROCAL M, Mata AM
    The Plasma Membrane Ca(2+)-ATPase, a Molecular Target for Tau-induced Cytosolic Calcium Dysregulation.
    Neuroscience. 2023;518:112-118.
    PubMed     Abstract available


  80. CAAMANO-MORENO M, Gargini R
    Tauopathies: The Role of Tau in Cellular Crosstalk and Synaptic Dysfunctions.
    Neuroscience. 2023;518:38-53.
    PubMed     Abstract available


  81. ANDRES-BENITO P, Carmona M, Pirla MJ, Torrejon-Escribano B, et al
    Dysregulated Protein Phosphorylation as Main Contributor of Granulovacuolar Degeneration at the First Stages of Neurofibrillary Tangles Pathology.
    Neuroscience. 2023;518:119-140.
    PubMed     Abstract available


  82. CONCEPCION FA, Ekstrom NA, Khan MN, Estes OO, et al
    Progressive Dysregulation of Tau Phosphorylation in an Animal Model of Temporal Lobe Epilepsy.
    Neuroscience. 2023 May 2:S0306-4522(23)00193.
    PubMed     Abstract available


    April 2023
  83. KLEPL D, He F, Wu M, Blackburn DJ, et al
    Cross-Frequency Multilayer Network Analysis with Bispectrum-based Functional Connectivity: A Study of Alzheimer's Disease.
    Neuroscience. 2023 Apr 28:S0306-4522(23)00167.
    PubMed     Abstract available


  84. MURRAY HC, Saar G, Bai L, Bouraoud N, et al
    Progressive Spread of Beta-amyloid Pathology in an Olfactory-driven Amyloid Precursor Protein Mouse Model.
    Neuroscience. 2023;516:113-124.
    PubMed     Abstract available


    March 2023
  85. REN S, Li J, Huang L, Huang Q, et al
    Brain Functional Alterations and Association with Cognition in People with Preclinical Subjective Cognitive Decline and Objective Subtle Cognitive Difficulties.
    Neuroscience. 2023;513:137-144.
    PubMed     Abstract available


    February 2023
  86. PLACHEZ C, Tsytsarev V, Zhao S, Erzurumlu RS, et al
    Amyloid Deposition and Dendritic Complexity of Corticocortical Projection Cells in Five Familial Alzheimer's Disease Mouse.
    Neuroscience. 2023;512:85-98.
    PubMed     Abstract available


    October 2021
  87. VIARD A, Eustache F, Segobin S
    History of Magnetic Resonance Imaging: A Trip Down Memory Lane.
    Neuroscience. 2021;474:3-13.
    PubMed     Abstract available


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