Retrieve available abstracts of 64 articles: HTML format
Single Articles
October 2025
Erratum: Barron et al., "Ligand for Translocator Protein Reverses Pathology in a
Mouse Model of Alzheimer's Disease".
J Neurosci. 2025;45:e1634252025. PubMed
September 2025
QU Y, Wu Y, Xu X, Cheng W, et al MiR-153 Prevents NRF2 Nuclear Translocation to Drive Hypoperfusion-Related
Cognitive Deficits by Targeting KPNA5.
J Neurosci. 2025;45:e2148242025. PubMedAbstract available
August 2025
WEISS BE, Gant JC, Lin RL, Gollihue JL, et al Disrupted calcium dynamics in reactive astrocytes occur with endfeet-arteriole
decoupling in an amyloid mouse model of Alzheimer's disease.
J Neurosci. 2025 Aug 15:e0349252025. doi: 10.1523/JNEUROSCI.0349-25.2025. PubMedAbstract available
June 2025
GERASIMOV E, Rakovskaya A, Pchitskaya E, Vlasova O, et al A positive allosteric modulator of the SERCA pump rescues hippocampal neuronal
circuits dysfunction and cognitive defects in a mouse model of Alzheimer's
disease.
J Neurosci. 2025 Jun 24:e2337242025. doi: 10.1523/JNEUROSCI.2337-24.2025. PubMedAbstract available
JIANG Y, Sachdeva K, Goulbourne CN, Berg MJ, et al Increased neuronal expression of the early endosomal adaptor APPL1 replicates
Alzheimer's Disease-related endosomal and synaptic dysfunction with cholinergic
neurodegeneration.
J Neurosci. 2025 Jun 13:e2331242025. doi: 10.1523/JNEUROSCI.2331-24.2025. PubMedAbstract available
May 2025
NICODEMUS J, Liu CS, Ransom L, Tan V, et al Sequence diversity and encoded enzymatic differences of monocistronic L1 ORF2
mRNA variants in the aged normal and Alzheimer's disease brain.
J Neurosci. 2025 May 14:e2298242025. doi: 10.1523/JNEUROSCI.2298-24.2025. PubMedAbstract available
April 2025
MORITO T, Hashimoto S, Takamura R, Watamura N, et al The Role of Neprilysin and Insulin-Degrading Enzyme in the Etiology of Sporadic
Alzheimer's Disease.
J Neurosci. 2025 Apr 29:e2152242025. doi: 10.1523/JNEUROSCI.2152-24.2025. PubMedAbstract available
BATTOCCHIO E A New Molecular Mechanism for the Late-Onset Alzheimer's Disease Risk Gene CD2AP.
J Neurosci. 2025;45:e0046252025. PubMed
March 2025
Retraction: Larson et al., "The Complex PrP(c)-Fyn Couples Human Oligomeric Abeta
with Pathological Tau Changes in Alzheimer's Disease".
J Neurosci. 2025 Mar 6:e0301252025. doi: 10.1523/JNEUROSCI.0301-25.2025. PubMed
Retraction: Larson et al., "Soluble alpha-Synuclein is a Novel Modulator of
Alzheimer's Disease Pathophysiology".
J Neurosci. 2025 Mar 6:e0300252025. doi: 10.1523/JNEUROSCI.0300-25.2025. PubMed
February 2025
JAVED E, Suarez-Mendez I, Susi G, Roman JV, et al A Shift Toward Supercritical Brain Dynamics Predicts Alzheimer's Disease
Progression.
J Neurosci. 2025;45:e0688242024. PubMedAbstract available
January 2025
FOLEY KE, Weekman EM, Krick KE, Johnson SN, et al Acute Communication Between Microglia and Nonparenchymal Immune Cells in the
Anti-Abeta Antibody-Injected Cortex.
J Neurosci. 2025;45:e1456242024. PubMedAbstract available
SUN X, Pan S, Li D, Su M, et al Cell adhesion molecule protocadherin-gammaC5 ameliorates Abeta plaque pathogenesis by
modulating astrocyte function in Alzheimer's disease.
J Neurosci. 2025 Jan 22:e0967242025. doi: 10.1523/JNEUROSCI.0967-24.2025. PubMedAbstract available
December 2024
Erratum: Tosi et al., "The Network Structure of Cognitive Impairment: From
Subjective Cognitive Decline to Alzheimer's Disease".
J Neurosci. 2024 Dec 23:e2082242024. doi: 10.1523/JNEUROSCI.2082-24.2024. PubMed
HOUCHOIS JR, Attwood JE The Challenges of Modulating Neuroinflammation in Alzheimer's Disease and
Multiple Sclerosis with TREM2 Agonistic Antibodies.
J Neurosci. 2024;44:e1869242024. PubMed
DUNN J, Moore C, Kim NS, Gao T, et al Transcription Factor-Wide Association Studies (TF-WAS) to Identify Functional
SNPs in Alzheimer's Disease.
J Neurosci. 2024 Dec 2:e1800242024. doi: 10.1523/JNEUROSCI.1800-24.2024. PubMedAbstract available
November 2024
JANG E, Hoxha K, Mozier D, Insana A, et al Targeting Endogenous Tau in Seeded Tauopathy Models Inhibits Tau Spread.
J Neurosci. 2024;44:e0877242024. PubMedAbstract available
SHIMOHAMA S, Fujioka R, Mihira N, Sekiguchi M, et al The Icelandic Mutation (APP-A673T) Is Protective against Amyloid Pathology In
Vivo.
J Neurosci. 2024;44:e0223242024. PubMedAbstract available
October 2024
MIRFAKHAR FS, Castanheira J, Domingues R, Ramalho JS, et al The Alzheimer's disease risk gene CD2AP functions in dendritic spines by
remodeling F-actin.
J Neurosci. 2024 Oct 15:e1734232024. doi: 10.1523/JNEUROSCI.1734-23.2024. PubMedAbstract available
CAPOCCHI JK, Figueroa-Romero C, Dunham SJB, Faraci G, et al Symposium: What Does the Microbiome Tell Us about Prevention and Treatment of
AD/ADRD?
J Neurosci. 2024;44:e1295242024. PubMedAbstract available
September 2024
ZHANG D, Penwell T, Chen YH, Koehler A, et al G-Protein Signaling in Alzheimer's Disease: Spatial Expression Validation of
Semi-Supervised Deep Learning Based Computational Framework.
J Neurosci. 2024 Sep 26:e0587242024. doi: 10.1523/JNEUROSCI.0587-24.2024. PubMedAbstract available
DUGAN BJ, Dockery M Sex-Dependent Synaptic Alterations in a Mouse Model of Alzheimer's Disease.
J Neurosci. 2024;44:e0961242024. PubMed
July 2024
LIN D, Gold A, Kaye S, Atkinson JR, et al Arachidonic Acid Mobilization and Peroxidation Promote Microglial Dysfunction in
Abeta Pathology.
J Neurosci. 2024;44:e0202242024. PubMedAbstract available
STELZER GT, Lima-Filho RAS Amyloid-beta as a Key Player in Cerebrovascular Dysfunction in Alzheimer's Disease.
J Neurosci. 2024;44:e0663242024. PubMed
June 2024
ETXEBERRIA A, Shen YA, Vito S, Silverman S, et al Neutral or detrimental effects of TREM2 agonist antibodies in preclinical models
of Alzheimer's Disease and Multiple Sclerosis.
J Neurosci. 2024 Jun 3:e2347232024. doi: 10.1523/JNEUROSCI.2347-23.2024. PubMedAbstract available
TOSI G, Nigro S, Urso D, Spinosa V, et al The network structure of cognitive impairment: from Subjective Cognitive Decline
to Alzheimer's Disease.
J Neurosci. 2024 Jun 3:e1344232023. doi: 10.1523/JNEUROSCI.1344-23.2023. PubMedAbstract available
May 2024
JACOBSON KR, Song H Changes in the Extracellular Matrix with Aging: A Larger Role in Alzheimer's
Disease.
J Neurosci. 2024;44:e0081242024. PubMed
Erratum: Iba et al., "Synthetic Tau Fibrils Mediate Transmission of
Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like
Tauopathy".
J Neurosci. 2024 May 28:e0865242024. doi: 10.1523/JNEUROSCI.0865-24.2024. PubMed
LIU Y, Kwok W, Yoon H, Ryu JC, et al Imbalance in Glucose Metabolism Regulates the Transition of Microglia from
Homeostasis to Disease-Associated Microglia Stage 1.
J Neurosci. 2024;44:e1563232024. PubMedAbstract available
April 2024
ZHANG A, Wengler K, Zhu X, Horga G, et al Altered hierarchical gradients of intrinsic neural timescales in mild cognitive
impairment and Alzheimer's disease.
J Neurosci. 2024 Apr 24:e2024232024. doi: 10.1523/JNEUROSCI.2024-23.2024. PubMedAbstract available
MURAKAMI R, Watanabe H, Hashimoto H, Kashiwagi-Hakozaki M, et al Inhibitory roles of Apolipoprotein E Christchurch astrocytes in curbing tau
propagation using human pluripotent stem cell-derived models.
J Neurosci. 2024 Apr 22:e1709232024. doi: 10.1523/JNEUROSCI.1709-23.2024. PubMedAbstract available
AHMADI K, Pereira JB, Westen DV, Pasternak O, et al Fixel-based analysis reveals tau-related white matter changes in early stages of
Alzheimer's disease.
J Neurosci. 2024 Apr 2:e0538232024. doi: 10.1523/JNEUROSCI.0538-23.2024. PubMedAbstract available
March 2024
YE Q, Gast G, Wilfley EG, Huynh H, et al Monosynaptic rabies tracing reveals sex- and age-dependent dorsal subiculum
connectivity alterations in an Alzheimer's disease mouse model.
J Neurosci. 2024 Mar 19:e1796232024. doi: 10.1523/JNEUROSCI.1796-23.2024. PubMedAbstract available
February 2024
REN Q, Wang S, Li J, Cao K, et al Novel social stimulation ameliorates memory deficit in Alzheimer's disease model
through activating alpha-secretase.
J Neurosci. 2024 Feb 28:e1689232024. doi: 10.1523/JNEUROSCI.1689-23.2024. PubMedAbstract available
ZHOU J, Wearn A, Huck J, Hughes C, et al Iron deposition and distribution across the hippocampus is associated with
pattern separation and pattern completion in older adults at risk for Alzheimer's
disease.
J Neurosci. 2024 Feb 22:e1973232024. doi: 10.1523/JNEUROSCI.1973-23.2024. PubMedAbstract available
MABOUDIAN SA, Willbrand EH, Jagust WJ, Weiner KS, et al Defining overlooked structures reveals new associations between cortex and
cognition in aging and Alzheimer's disease.
J Neurosci. 2024 Feb 21:e1714232024. doi: 10.1523/JNEUROSCI.1714-23.2024. PubMedAbstract available
KIM CM, Diez I, Bueicheku E, Ahn S, et al Spatiotemporal Correlation between Amyloid and Tau Accumulations Underlies
Cognitive Changes in Aging.
J Neurosci. 2024;44:e0488232023. PubMedAbstract available
PHILLIPS JS, Robinson JL, Cousins KAQ, Wolk DA, et al Polypathologic Associations with Gray Matter Atrophy in Neurodegenerative
Disease.
J Neurosci. 2024;44:e0808232023. PubMedAbstract available
January 2024
NIRAULA S, Yan SS, Subramanian J Amyloid Pathology Impairs Experience-Dependent Inhibitory Synaptic Plasticity.
J Neurosci. 2024;44:e0702232023. PubMedAbstract available
LOWERISON MR, Sekaran NVC, Dong Z, Chen X, et al Super-resolution ultrasound reveals cerebrovascular impairment in a mouse model
of Alzheimer's Disease.
J Neurosci. 2024 Jan 22:e1251232024. doi: 10.1523/JNEUROSCI.1251-23.2024. PubMedAbstract available
November 2023
LUKE R, Alymova I Unraveling the Mechanisms Underlying Disordered Sleep in Alzheimer's Disease.
J Neurosci. 2023;43:7899-7901. PubMed
BARTOSCH AMW, Youth EHH, Hansen S, Wu Y, et al ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in
Alzheimer's disease.
J Neurosci. 2023 Nov 22:JN-RM-2324-22. doi: 10.1523/JNEUROSCI.2324-22.2023. PubMedAbstract available
IWATSUBO T, Irizarry MC, Lewcock JW, Carrillo MC, et al Alzheimer's targeted treatments: focus on amyloid and inflammation.
J Neurosci. 2023 Nov 14:JN-DP-1576-23. doi: 10.1523/JNEUROSCI.1576-23.2023. PubMedAbstract available
October 2023
ECKMAN EA, Clausen DM, Sole-Domenech S, Lee CW, et al Nascent Abeta42 fibrillization in synaptic endosomes precedes plaque formation in a
mouse model of Alzheimer's like beta-amyloidosis.
J Neurosci. 2023 Oct 26:JN-RM-1318-23. doi: 10.1523/JNEUROSCI.1318-23.2023. PubMedAbstract available
SANO T, Ochiai T, Nagayama T, Nakamura A, et al Genetic Reduction of Insulin Signaling Mitigates Amyloid-beta Deposition by
Promoting Expression of Extracellular Matrix Proteins in the Brain.
J Neurosci. 2023;43:7226-7241. PubMedAbstract available
ALLARD S, Hussain Shuler MG Cholinergic Reinforcement Signaling Is Impaired by Amyloidosis Prior to Its
Synaptic Loss.
J Neurosci. 2023;43:6988-7005. PubMedAbstract available
BHEMBRE N, Bonthron C, Opazo P Synaptic Compensatory Plasticity in Alzheimer's Disease.
J Neurosci. 2023;43:6833-6840. PubMedAbstract available
September 2023
ZHANG Z, Chan MY, Han L, Carreno CA, et al Dissociable effects of Alzheimer's Disease-related cognitive dysfunction and
aging on functional brain network segregation.
J Neurosci. 2023 Sep 15:JN-RM-0579-23. doi: 10.1523/JNEUROSCI.0579-23.2023. PubMedAbstract available
CHEN L, Christenson Wick Z, Vetere LM, Vaughan N, et al Progressive excitability changes in the medial entorhinal cortex in the 3xTg
mouse model of Alzheimer's disease pathology.
J Neurosci. 2023 Sep 15:JN-RM-1204-23. doi: 10.1523/JNEUROSCI.1204-23.2023. PubMedAbstract available
YIN P, Cai Y, Cui T, Berg AJ, et al Glial Sphingosine-mediated Epigenetic Regulation Stabilizes Synaptic Function in
Drosophila Models of Alzheimer's Disease.
J Neurosci. 2023 Sep 5:JN-RM-0515-23. doi: 10.1523/JNEUROSCI.0515-23.2023. PubMedAbstract available
August 2023
CASSADY KE, Chen X, Adams JN, Harrison TM, et al Effect of Alzheimer's pathology on task-related brain network reconfiguration in
aging.
J Neurosci. 2023 Aug 18:JN-RM-0023-23. doi: 10.1523/JNEUROSCI.0023-23.2023. PubMedAbstract available
ZHOU Y, Xie L, der JS, Schuster IS, et al Dietary fiber and microbiota metabolite receptors enhance cognition and alleviate
disease in the 5xFAD mouse model of Alzheimer's disease.
J Neurosci. 2023 Aug 17:JN-RM-0724-23. doi: 10.1523/JNEUROSCI.0724-23.2023. PubMedAbstract available
ONDREJCAK T, Klyubin I, Hu NW, O'Malley TT, et al Tau and Amyloid beta Protein in Patient-Derived Aqueous Brain Extracts Act
Concomitantly to Disrupt Long-Term Potentiation in Vivo.
J Neurosci. 2023;43:5870-5879. PubMedAbstract available
YAO AY, Halloran PJ, Ge Y, Singh N, et al Bace1 deletion in the adult reverses epileptiform activity and sleep-wake
disturbances in AD mice.
J Neurosci. 2023 Aug 3:JN-RM-2124-22. doi: 10.1523/JNEUROSCI.2124-22.2023. PubMedAbstract available
July 2023
LENZ M, Eichler A, Kruse P, Galanis C, et al The Amyloid Precursor Protein Regulates Synaptic Transmission at Medial Perforant
Path Synapses.
J Neurosci. 2023;43:5290-5304. PubMedAbstract available
June 2023
KELLY P, Sanchez-Mico MV, Hou SS, Whiteman S, et al Neuronally Derived Soluble Abeta Evokes Cell-Wide Astrocytic Calcium
Dysregulation in Absence of Amyloid Plaques in Vivo.
J Neurosci. 2023;43:4926-4940. PubMedAbstract available
MEDINA-SAMAME A, Paller E, Bril MR, Archvadze A, et al Role of Neurexins in Alzheimer's Disease.
J Neurosci. 2023;43:4194-4196. PubMed
May 2023
LANDRY O, Francois A, Oye Mintsa Mi-Mba MF, Traversy MT, et al Postsynaptic protein Shank3a deficiency synergizes with Alzheimer's disease
neuropathology to impair cognitive performance in the 3xTg-AD murine model.
J Neurosci. 2023 May 30:JN-RM-1945-22. doi: 10.1523/JNEUROSCI.1945-22.2023. PubMedAbstract available
BRYANT A, Li Z, Jayakumar R, Serrano-Pozo A, et al Endothelial Cells are Heterogeneous in Different Brain Regions and are
Dramatically Altered in Alzheimer's Disease.
J Neurosci. 2023 May 17:JN-RM-0237-23. doi: 10.1523/JNEUROSCI.0237-23.2023. PubMedAbstract available
WALKER CK, Greathouse KM, Tuscher JJ, Dammer EB, et al Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies
TWF2 as a Modulator of Dendritic Spine Length.
J Neurosci. 2023;43:3764-3785. PubMedAbstract available
April 2023
ZHANG K, Chen L, Li Y, Paez AG, et al Differential Laminar Activation Dissociates Encoding and Retrieval in the Human
Medial and Lateral Entorhinal Cortex.
J Neurosci. 2023;43:2874-2884. PubMedAbstract available
March 2023
SOMPOL P, Gollihue JL, Weiss BE, Lin RL, et al Targeting Astrocyte Signaling Alleviates Cerebrovascular and Synaptic Function
Deficits in a Diet-Based Mouse Model of Small Cerebral Vessel Disease.
J Neurosci. 2023;43:1797-1813. PubMedAbstract available
MA F, Akolkar H, Xu J, Liu Y, et al The Amyloid Precursor Protein Modulates the Position and Length of the Axon
Initial Segment.
J Neurosci. 2023;43:1830-1844. PubMedAbstract available
February 2023
BHATNAGAR A, Krick K, Karisetty BC, Armour EM, et al Tip60's novel RNA-binding function modulates alternative splicing of pre-mRNA
targets implicated in Alzheimer's Disease.
J Neurosci. 2023 Feb 24:JN-RM-2331-22. doi: 10.1523/JNEUROSCI.2331-22.2023. PubMedAbstract available