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Alzheimer's Disease

Free Subscription Articles published in Brain Retrieve available abstracts of 154 articles: HTML format

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October 2025
1. RUIZ-REIG N, Virosztek M, Chehade G, Suelves N, et al
   KIF2A downregulation links amyloid-beta to Tau phosphorylation in Alzheimer's disease.
   Brain. 2025 Oct 10:awaf382. doi: 10.1093.
   PubMed     Abstract available
   
   
   
2. ALEXANDERSEN CG, Bassett DS, Goriely A, Chaggar P, et al
   Neuronal activity and amyloid-beta promote tau seeding in the entorhinal cortex in Alzheimer's disease.
   Brain. 2025 Oct 7:awaf374. doi: 10.1093.
   PubMed     Abstract available
   
   
   
3. KARLSSON L, Janelidze S, Barthelemy NR, Horie K, et al
   Reference proteins to improve Core 1 and Core 2 Alzheimer's disease CSF and plasma biomarkers.
   Brain. 2025 Oct 6:awaf375. doi: 10.1093.
   PubMed     Abstract available
   
   
   
4. VERBERK IMW, van Harten AC, van der Flier WM
   Opposing views or like-minded? International Working Group and Alzheimer's Association criteria.
   Brain. 2025 Oct 1:awaf366. doi: 10.1093.
   PubMed    
   
   
   September 2025
5. JOHNSON DR, Wiste HJ, Lowe V, Schwarz CG, et al
   Staging Alzheimer's disease through amyloid and tau PET.
   Brain. 2025 Sep 19:awaf346. doi: 10.1093.
   PubMed     Abstract available
   
   
   
6. PESCOLLER J, Dewenter A, Dehsarvi A, Steward A, et al
   Cortical tau deposition promotes atrophy in connected white matter regions in Alzheimer's disease.
   Brain. 2025 Sep 12:awaf339. doi: 10.1093.
   PubMed     Abstract available
   
   
   
7. YU L, Du L, Wang T, Barnes LL, et al
   Neuropathologic correlates of distinct plasma biomarker profiles in community-living older adults.
   Brain. 2025;148:3340-3349.
   PubMed     Abstract available
   
   
   August 2025
8. DE BRUIN H, Groot C, Barthel H, Bischof GN, et al
   Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease.
   Brain. 2025 Aug 14:awaf279. doi: 10.1093.
   PubMed     Abstract available
   
   
   
9. SKELLY D, Attfield KE, Fugger L
   T cells turn in Alzheimer's disease.
   Brain. 2025 Aug 14:awaf288. doi: 10.1093.
   PubMed    
   
   
   
10. ESPAY AJ, Ezzat K, Kepp KP, Daly T, et al
    Restoring amyloid-beta42 and gamma-secretase function in Alzheimer's disease.
    Brain. 2025 Aug 8:awaf294. doi: 10.1093.
    PubMed     Abstract available
    
    
    
11. M'BRA PEH, Hamilton LK, Moquin-Beaudry G, Mangahas CL, et al
    Medium-chain triglycerides improve cognition and systemic metabolism in mouse models of Alzheimer's disease.
    Brain. 2025 Aug 6:awaf267. doi: 10.1093.
    PubMed     Abstract available
    
    
    
12. BERSON E, Perna A, Bukhari S, Kim Y, et al
    Deep learning-based cell type profiles reveal signatures of Alzheimer's disease resilience and resistance.
    Brain. 2025 Aug 5:awaf285. doi: 10.1093.
    PubMed     Abstract available
    
    
    
13. SAADMAAN G, Dalmasso MC, Maria M, Lehtisalo J, et al
    Alzheimer and cardiovascular genetic scores and cognition: the FINGER randomized controlled trial.
    Brain. 2025 Aug 1:awaf277. doi: 10.1093.
    PubMed     Abstract available
    
    
    
14. ZUO M, Chang L, Neale N, Maameri L, et al
    The relationship between kidney health and neurodegenerative diseases.
    Brain. 2025;148:2616-2630.
    PubMed     Abstract available
    
    
    July 2025
15. HAMID M, Detroja TS, Tripathy SJ, Menon V, et al
    Sleep, pericyte subtypes and cognitive decline in adults with and without Alzheimer's disease.
    Brain. 2025 Jul 14:awaf161. doi: 10.1093.
    PubMed     Abstract available
    
    
    
16. ANAND C, Abdelnour F, Sipes B, Ma D, et al
    Selective vulnerability and resilience to Alzheimer's disease tauopathy as a function of genes and the connectome.
    Brain. 2025 Jul 9:awaf179. doi: 10.1093.
    PubMed     Abstract available
    
    
    
17. WEIL RS
    Seeing the trees in the wood: the importance of co-pathologies in Alzheimer's disease and dementia with Lewy bodies.
    Brain. 2025;148:2233-2234.
    PubMed    
    
    
    
18. WOODWORTH DC, Lou JJ, Yong WH, Head E, et al
    Common neuropathologic change drivers of hippocampal sclerosis of ageing.
    Brain. 2025;148:2400-2411.
    PubMed     Abstract available
    
    
    
19. CHEN J, Li Q, Ji B, Zhang K, et al
    Single-nucleus transcriptome atlas of the basal forebrain reveals diverse ageing-related pathways.
    Brain. 2025;148:2493-2508.
    PubMed     Abstract available
    
    
    
20. SILVA-RODRIGUEZ J, Labrador-Espinosa MA, Zhang L, Castro-Labrador S, et al
    The effect of Lewy body (co-)pathology on the clinical and imaging phenotype of amnestic patients.
    Brain. 2025;148:2441-2452.
    PubMed     Abstract available
    
    
    
21. ZAWAR I, Luniewski A, Gundlapalli R, Manning C, et al
    The association of seizure control with neuropathology in dementia.
    Brain. 2025;148:2469-2480.
    PubMed     Abstract available
    
    
    
22. CICOGNOLA C, Salvado G, Smith R, Palmqvist S, et al
    APOE4 impact on soluble and insoluble tau pathology is mostly influenced by amyloid-beta.
    Brain. 2025;148:2373-2383.
    PubMed     Abstract available
    
    
    
23. GRAHAM NSN, Zimmerman KA, Hain J, Rooney E, et al
    Biomarker evidence of neurodegeneration in mid-life former rugby players.
    Brain. 2025 Jul 3:awaf152. doi: 10.1093.
    PubMed     Abstract available
    
    
    June 2025
24. SCARMEAS N, Noriega De La Colina A
    The duality of disease: the Alzheimer's disease dilemma through the lens of nosos and asthenia.
    Brain. 2025 Jun 26:awaf239. doi: 10.1093.
    PubMed    
    
    
    
25. JIANG S, Srikanth M, Serpe R, Yavari S, et al
    Early proteasome downregulation and dysfunction drive proteostasis failure in Alzheimer's disease.
    Brain. 2025 Jun 9:awaf222. doi: 10.1093.
    PubMed     Abstract available
    
    
    
26. VELLONE D, Leon R, Goodarzi Z, Forkert ND, et al
    Mild behavioural impairment-apathy and core Alzheimer's disease cerebrospinal fluid biomarkers.
    Brain. 2025 Jun 2:awaf194. doi: 10.1093.
    PubMed     Abstract available
    
    
    May 2025
27. ABDEL-HALEEM AM, Casavant E, Toth B, Teng E, et al
    CSF proteomics of semorinemab Alzheimer's disease trials identifies cell-type specific signatures.
    Brain. 2025 May 28:awaf200. doi: 10.1093.
    PubMed     Abstract available
    
    
    
28. WISSE LEM, La Joie R
    Medial temporal lobe structural changes when Down syndrome and Alzheimer's disease collide.
    Brain. 2025 May 14:awaf176. doi: 10.1093.
    PubMed    
    
    
    
29. RICKENBACH C, Mallone A, Hausle L, Frei L, et al
    Altered T-cell reactivity in the early stages of Alzheimer's disease.
    Brain. 2025 May 5:awaf167. doi: 10.1093.
    PubMed     Abstract available
    
    
    April 2025
30. POMARA N, Imbimbo BP
    Making a diagnosis of Alzheimer's disease in asymptomatic individuals with positive biomarkers.
    Brain. 2025 Apr 28:awaf162. doi: 10.1093.
    PubMed    
    
    
    
31. SHARIF SF, Guan DX, Bodnar T, Joseph JT, et al
    Neuropsychiatric symptoms and progression to pathologically confirmed Alzheimer's disease.
    Brain. 2025 Apr 25:awaf156. doi: 10.1093.
    PubMed     Abstract available
    
    
    
32. ABANTO JT, Dwivedi AK, Imbimbo BP, Espay AJ, et al
    CSF amyloid-beta40 levels are not associated with efficacy outcomes in Alzheimer's disease trials.
    Brain. 2025 Apr 19:awaf143. doi: 10.1093.
    PubMed    
    
    
    
33. BUEHNER BJ, Morcillo-Nieto AO, Zsadanyi SE, Rozalem Aranha M, et al
    Medial temporal lobe atrophy in Down syndrome along the Alzheimer's disease continuum.
    Brain. 2025 Apr 17:awaf133. doi: 10.1093.
    PubMed     Abstract available
    
    
    
34. LU K, Baker J, Nicholas JM, Street RE, et al
    Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults.
    Brain. 2025;148:1302-1315.
    PubMed     Abstract available
    
    
    March 2025
35. PHILLIPS JM, Dumitrescu LC, Archer DB, Regelson AN, et al
    Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer's disease.
    Brain. 2025 Mar 20:awaf106. doi: 10.1093.
    PubMed     Abstract available
    
    
    February 2025
36. 
    Correction to: Plasma p-tau217 in Alzheimer's disease: Lumipulse and ALZpath SIMOA head-to-head comparison.
    Brain. 2025 Feb 6:awaf034. doi: 10.1093.
    PubMed    
    
    
    
37. LIU H, Marsh TW, Shi X, Renton AE, et al
    The landscape of autosomal-dominant Alzheimer's disease: global distribution and age of onset.
    Brain. 2025 Feb 4:awaf038. doi: 10.1093.
    PubMed     Abstract available
    
    
    
38. HUSAIN M
    Listening into hippocampal hyperexcitability in Alzheimer's disease.
    Brain. 2025;148:347-348.
    PubMed    
    
    
    
39. WARMENHOVEN N, Salvado G, Janelidze S, Mattsson-Carlgren N, et al
    A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests.
    Brain. 2025;148:416-431.
    PubMed     Abstract available
    
    
    January 2025
40. FERNANDEZ ARIAS J, Brum WS, Salvado G, Therriault J, et al
    Plasma phosphorylated tau217 strongly associates with memory deficits in the Alzheimer's disease spectrum.
    Brain. 2025 Jan 29:awaf033. doi: 10.1093.
    PubMed     Abstract available
    
    
    
41. CHAUVEAU L, Landeau B, Dautricourt S, Turpin AL, et al
    Anterior-temporal network hyperconnectivity is key to Alzheimer's disease: from ageing to dementia.
    Brain. 2025 Jan 15:awaf008. doi: 10.1093.
    PubMed     Abstract available
    
    
    
42. GRAHAM AC, Bellou E, Harwood JC, Yaman U, et al
    Human longevity and Alzheimer's disease variants act via microglia and oligodendrocyte gene networks.
    Brain. 2025 Jan 9:awae339. doi: 10.1093.
    PubMed     Abstract available
    
    
    
43. VAN DER FLIER WM, Heneka MT
    Zooming in on brain inflammation in Alzheimer's disease.
    Brain. 2025;148:1-2.
    PubMed    
    
    
    
44. TIAN F, Wang Y, Qian ZM, Ran S, et al
    Plasma metabolomic signature of healthy lifestyle, structural brain reserve and risk of dementia.
    Brain. 2025;148:143-153.
    PubMed     Abstract available
    
    
    December 2024
45. PILOTTO A, Quaresima V, Trasciatti C, Tolassi C, et al
    Plasma p-tau217 in Alzheimer's disease: Lumipulse and ALZpath SIMOA head-to-head comparison.
    Brain. 2024 Dec 16:awae368. doi: 10.1093.
    PubMed     Abstract available
    
    
    
46. WANG D, Honnorat N, Toledo JB, Li K, et al
    Deep learning reveals pathology-confirmed neuroimaging signatures in Alzheimer's, vascular and Lewy body dementias.
    Brain. 2024 Dec 9:awae388. doi: 10.1093.
    PubMed     Abstract available
    
    
    
47. LEE SH, Bae EJ, Perez-Acuna D, Jung MK, et al
    Amyloid-beta-activated microglia can induce compound proteinopathies.
    Brain. 2024;147:4105-4120.
    PubMed     Abstract available
    
    
    November 2024
48. DUONG MT, Das SR, Khandelwal P, Lyu X, et al
    Hypometabolic mismatch with atrophy and tau pathology in mixed Alzheimer and Lewy body disease.
    Brain. 2024 Nov 22:awae352. doi: 10.1093.
    PubMed     Abstract available
    
    
    
49. KOCH G, Altomare D, Benussi A, Brechet L, et al
    The emerging field of non-invasive brain stimulation in Alzheimer's disease.
    Brain. 2024 Nov 20:awae292. doi: 10.1093.
    PubMed     Abstract available
    
    
    
50. COLLOBY SJ, McAleese KE, Walker L, Erskine D, et al
    Patterns of tau, amyloid and synuclein pathology in ageing, Alzheimer's disease and synucleinopathies.
    Brain. 2024 Nov 12:awae372. doi: 10.1093.
    PubMed     Abstract available
    
    
    
51. PELKMANS W, Gispert JD
    Astroglial reactivity is a key modulator of Alzheimer's disease pathological progression.
    Brain. 2024 Nov 8:awae354. doi: 10.1093.
    PubMed    
    
    
    
52. MACMULLEN C, Sharma N, Davis RL
    Mitochondrial dynamics and bioenergetics in Alzheimer's induced pluripotent stem cell-derived neurons.
    Brain. 2024 Nov 8:awae364. doi: 10.1093.
    PubMed     Abstract available
    
    
    
53. DALY T, Imbimbo BP
    Metformin may reduce Alzheimer's disease risk by increasing soluble amyloid-beta42 levels.
    Brain. 2024 Nov 8:awae367. doi: 10.1093.
    PubMed    
    
    
    
54. WELIKOVITCH LA, Mate de Gerando A, Khasnavis A, Bhavsar H, et al
    Tau, synapse loss and gliosis progress in an Alzheimer's mouse model after amyloid-beta immunotherapy.
    Brain. 2024 Nov 6:awae345. doi: 10.1093.
    PubMed     Abstract available
    
    
    
55. SAKATO Y, Shima A, Terada Y, Takeda K, et al
    Delineating three distinct spatiotemporal patterns of brain atrophy in Parkinson's disease.
    Brain. 2024;147:3702-3713.
    PubMed     Abstract available
    
    
    
56. BENJAMIN-ZUKERMAN T, Shimon G, Gaine ME, Dakwar A, et al
    A mutation in the PRKAR1B gene drives pathological mechanisms of neurodegeneration across species.
    Brain. 2024;147:3890-3905.
    PubMed     Abstract available
    
    
    October 2024
57. KOVACS GG, Katsumata Y, Wu X, Aung KZ, et al
    Amyloid-beta predominant Alzheimer's disease neuropathologic change.
    Brain. 2024 Oct 17:awae325. doi: 10.1093.
    PubMed     Abstract available
    
    
    
58. KATSUMI Y, Howe IA, Eckbo R, Wong B, et al
    Default mode network tau predicts future clinical decline in atypical early Alzheimer's disease.
    Brain. 2024 Oct 16:awae327. doi: 10.1093.
    PubMed     Abstract available
    
    
    
59. AGRAWAL S, Yu L, Leurgans SE, Kapasi A, et al
    Grey matter ageing-related tau astrogliopathy: associations with brain pathologies and cognitive decline.
    Brain. 2024;147:3501-3512.
    PubMed     Abstract available
    
    
    
60. REUS LM, Jansen IE, Tijms BM, Visser PJ, et al
    Connecting dementia risk loci to the CSF proteome identifies pathophysiological leads for dementia.
    Brain. 2024;147:3522-3533.
    PubMed     Abstract available
    
    
    September 2024
61. ABANTO J, Dwivedi AK, Imbimbo BP, Espay AJ, et al
    Increases in amyloid-beta42 slow cognitive and clinical decline in Alzheimer's disease trials.
    Brain. 2024 Sep 11:awae216. doi: 10.1093.
    PubMed     Abstract available
    
    
    August 2024
62. ZELEK WM, Bevan RJ, Nimmo J, Dewilde M, et al
    Brain-penetrant complement inhibition mitigates neurodegeneration in an Alzheimer's disease mouse model.
    Brain. 2024 Aug 31:awae278. doi: 10.1093.
    PubMed     Abstract available
    
    
    
63. SHAHIDEHPOUR RK, Nelson PT, Katsumata Y, Bachstetter AD, et al
    Exploring the link between dystrophic microglia and the spread of Alzheimer's neuropathology.
    Brain. 2024 Aug 5:awae258. doi: 10.1093.
    PubMed     Abstract available
    
    
    
64. GOMEZ-MURCIA V, Launay A, Carvalho K, Burgard A, et al
    Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice.
    Brain. 2024;147:2691-2705.
    PubMed     Abstract available
    
    
    July 2024
65. YANG Y, Chen H, Huang S, Chen H, et al
    BOK-engaged mitophagy alleviates neuropathology in Alzheimer's disease.
    Brain. 2024 Jul 25:awae241. doi: 10.1093.
    PubMed     Abstract available
    
    
    
66. MATTSSON-CARLGREN N
    Disentangling genetic risks for development and progression of Alzheimer's disease.
    Brain. 2024 Jul 18:awae237. doi: 10.1093.
    PubMed    
    
    
    
67. RAMANAN S, Akarca D, Henderson SK, Rouse MA, et al
    The graded multidimensional geometry of phenotypic variation and progression in neurodegenerative syndromes.
    Brain. 2024 Jul 17:awae233. doi: 10.1093.
    PubMed     Abstract available
    
    
    
68. APPLETON J, Finn Q, Zanotti-Fregonara P, Yu M, et al
    Brain inflammation co-localizes highly with tau in mild cognitive impairment due to early-onset Alzheimer's disease.
    Brain. 2024 Jul 16:awae234. doi: 10.1093.
    PubMed     Abstract available
    
    
    
69. CAI H, Zhao T, Pang Y, Fu X, et al
    Systemic inflammatory markers in ageing, Alzheimer's disease and other dementias.
    Brain. 2024 Jul 15:awae230. doi: 10.1093.
    PubMed     Abstract available
    
    
    
70. BARBA L, Abu-Rumeileh S, Barthel H, Massa F, et al
    Clinical and diagnostic implications of Alzheimer's disease copathology in Lewy body disease.
    Brain. 2024 Jul 11:awae203. doi: 10.1093.
    PubMed     Abstract available
    
    
    
71. DEVULDER A, Vanderlinden G, Van Langenhoven L, Testelmans D, et al
    Epileptic activity on foramen ovale electrodes is associated with sleep and tau pathology in Alzheimer's disease.
    Brain. 2024 Jul 11:awae231. doi: 10.1093.
    PubMed     Abstract available
    
    
    
72. HUSAIN M
    The heterogeneity of Alzheimer's disease.
    Brain. 2024;147:2259-2260.
    PubMed    
    
    
    
73. OKKELS N, Grothe MJ, Taylor JP, Hasselbalch SG, et al
    Cholinergic changes in Lewy body disease: implications for presentation, progression and subtypes.
    Brain. 2024;147:2308-2324.
    PubMed     Abstract available
    
    
    
74. NILSSON J, Pichet Binette A, Palmqvist S, Brum WS, et al
    Cerebrospinal fluid biomarker panel for synaptic dysfunction in a broad spectrum of neurodegenerative diseases.
    Brain. 2024;147:2414-2427.
    PubMed     Abstract available
    
    
    June 2024
75. PERETTI DE, Boccalini C, Ribaldi F, Scheffler M, et al
    Association of glial fibrillary acid protein, Alzheimer's disease pathology and cognitive decline.
    Brain. 2024 Jun 28:awae211. doi: 10.1093.
    PubMed     Abstract available
    
    
    
76. 
    Correction to: Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis.
    Brain. 2024 Jun 28:awae208. doi: 10.1093.
    PubMed    
    
    
    
77. OLNEY KC, Rabichow BE, Wojtas AM, DeTure M, et al
    Distinct transcriptional alterations distinguish Lewy body disease from Alzheimer's disease.
    Brain. 2024 Jun 25:awae202. doi: 10.1093.
    PubMed     Abstract available
    
    
    
78. BALLERINI A, Biagioli N, Carbone C, Chiari A, et al
    Late-onset temporal lobe epilepsy: insights from brain atrophy and Alzheimer's disease biomarkers.
    Brain. 2024 Jun 25:awae207. doi: 10.1093.
    PubMed     Abstract available
    
    
    
79. COOMANS EM, Ossenkoppele R
    The implications of amyloid-beta pathology: only time will tell.
    Brain. 2024;147:1934-1936.
    PubMed    
    
    
    May 2024
80. ALTMANN A, Aksman LM, Oxtoby NP, Young A, et al
    Towards cascading genetic risk in Alzheimer's disease.
    Brain. 2024 May 31:awae176. doi: 10.1093.
    PubMed     Abstract available
    
    
    
81. CHEN F, Zhao J, Meng F, He F, et al
    The vascular contribution of apolipoprotein E to Alzheimer's disease.
    Brain. 2024 May 15:awae156. doi: 10.1093.
    PubMed     Abstract available
    
    
    
82. SOCH J, Richter A, Kizilirmak JM, Schutze H, et al
    Single-value brain activity scores reflect both severity and risk across the Alzheimer's continuum.
    Brain. 2024 May 14:awae149. doi: 10.1093.
    PubMed     Abstract available
    
    
    
83. BLUM D, Levi S
    Targeting excitatory:inhibitory network imbalance in Alzheimer's disease.
    Brain. 2024 May 13:awae146. doi: 10.1093.
    PubMed    
    
    
    
84. SANCHEZ-JUAN P, Valeriano-Lorenzo E, Ruiz-Gonzalez A, Pastor AB, et al
    Serum GFAP levels correlate with astrocyte reactivity, post-mortem brain atrophy and neurofibrillary tangles.
    Brain. 2024;147:1667-1679.
    PubMed     Abstract available
    
    
    
85. DING F, Sun Q, Long C, Rasmussen RN, et al
    Dysregulation of extracellular potassium distinguishes healthy ageing from neurodegeneration.
    Brain. 2024;147:1726-1739.
    PubMed     Abstract available
    
    
    April 2024
86. CODY KA, Langhough RE, Zammit MD, Clark L, et al
    Characterizing brain tau and cognitive decline along the amyloid timeline in Alzheimer's disease.
    Brain. 2024 Apr 26:awae116. doi: 10.1093.
    PubMed     Abstract available
    
    
    
87. BARBOUR AJ, Gourmaud S, Lancaster E, Li X, et al
    Seizures exacerbate excitatory: inhibitory imbalance in Alzheimer's disease and 5XFAD mice.
    Brain. 2024 Apr 25:awae126. doi: 10.1093.
    PubMed     Abstract available
    
    
    
88. BAUMEISTER H, Vogel JW, Insel PS, Kleineidam L, et al
    A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings.
    Brain. 2024 Apr 24:awae118. doi: 10.1093.
    PubMed     Abstract available
    
    
    
89. LIMBERGER C, Zimmer ER
    Blood GFAP reflects astrocyte reactivity to Alzheimer's pathology in post-mortem brain tissue.
    Brain. 2024 Apr 18:awae104. doi: 10.1093.
    PubMed    
    
    
    
90. 
    Correction to: Disrupted daily activity/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer's dementia.
    Brain. 2024 Apr 10:awae103. doi: 10.1093.
    PubMed    
    
    
    
91. WANG YT, Therriault J, Servaes S, Tissot C, et al
    Sex-specific modulation of amyloid-beta on tau phosphorylation underlies faster tangle accumulation in females.
    Brain. 2024;147:1497-1510.
    PubMed     Abstract available
    
    
    
92. TANAKA H, Martinez-Valbuena I, Forrest SL, Couto B, et al
    Distinct involvement of the cranial and spinal nerves in progressive supranuclear palsy.
    Brain. 2024;147:1399-1411.
    PubMed     Abstract available
    
    
    
93. CORRIVEAU-LECAVALIER N, Barnard LR, Botha H, Graff-Radford J, et al
    Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases.
    Brain. 2024;147:1483-1496.
    PubMed     Abstract available
    
    
    March 2024
94. HUNG C, Fertan E, Livesey FJ, Klenerman D, et al
    APP antisense oligonucleotides reduce Abeta aggregation and rescue endolysosomal dysfunction in Alzheimer's disease.
    Brain. 2024 Mar 25:awae092. doi: 10.1093.
    PubMed     Abstract available
    
    
    
95. RODRIGUEZ-RODRIGUEZ P, Arroyo-Garcia LE, Tsagkogianni C, Li L, et al
    A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer's disease vulnerable neurons.
    Brain. 2024 Mar 11:awae051. doi: 10.1093.
    PubMed     Abstract available
    
    
    
96. RODRIGUEZ-VIEITEZ E, Vannini P, Montal V, Graff C, et al
    Cortical microstructural imaging from diffusion MRI: towards sensitive biomarkers for clinical trials.
    Brain. 2024;147:746-748.
    PubMed    
    
    
    
97. DE MEYER S, Blujdea ER, Schaeverbeke J, Reinartz M, et al
    Longitudinal associations of serum biomarkers with early cognitive, amyloid and grey matter changes.
    Brain. 2024;147:936-948.
    PubMed     Abstract available
    
    
    February 2024
98. YANG HS, Yau WW, Carlyle BC, Trombetta BA, et al
    Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease.
    Brain. 2024 Feb 5:awae034. doi: 10.1093.
    PubMed     Abstract available
    
    
    
99. AHMED H, Wang Y, Griffiths WJ, Levey AI, et al
    Brain cholesterol and Alzheimer's disease: challenges and opportunities in probe and drug development.
    Brain. 2024 Feb 1:awae028. doi: 10.1093.
    PubMed     Abstract available
    
    
    
100. ALBERT-GASCO H, Smith HL, Alvarez-Castelao B, Swinden D, et al
     Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration.
     Brain. 2024;147:649-664.
     PubMed     Abstract available
     
     
     January 2024
101. KUMAR M, Quittot N, Dujardin S, Schlaffner CN, et al
     Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments.
     Brain. 2024 Jan 18:awad378. doi: 10.1093.
     PubMed     Abstract available
     
     
     
102. KIIANITSA K, Lukes ME, Hayes BJ, Brutman J, et al
     TREM2 variants that cause early dementia and increase Alzheimer's disease risk affect gene splicing.
     Brain. 2024 Jan 16:awae014. doi: 10.1093.
     PubMed     Abstract available
     
     
     
103. HAN Y, Chen K, Zhang B, Yu H, et al
     Maf1 loss regulates spinogenesis and attenuates cognitive impairment in Alzheimer's disease.
     Brain. 2024 Jan 16:awae015. doi: 10.1093.
     PubMed     Abstract available
     
     
     
104. QIN C, Chen M, Dong MH, Yang S, et al
     Soluble TREM2 triggers microglial dysfunction in neuromyelitis optica spectrum disorders.
     Brain. 2024;147:163-176.
     PubMed     Abstract available
     
     
     December 2023
105. SAMANTA S, Akhter F, Roy A, Chen D, et al
     New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer's disease.
     Brain. 2023 Dec 26:awad432. doi: 10.1093.
     PubMed     Abstract available
     
     
     
106. SPOTORNO N, Strandberg O, Stomrud E, Janelidze S, et al
     Diffusion MRI tracks cortical microstructural changes during the early stages of Alzheimer's disease.
     Brain. 2023 Dec 21:awad428. doi: 10.1093.
     PubMed     Abstract available
     
     
     
107. STOUFFER KM, Grande X, Duezel E, Johansson M, et al
     Amidst an amygdala renaissance in Alzheimer's disease.
     Brain. 2023 Dec 18:awad411. doi: 10.1093.
     PubMed     Abstract available
     
     
     
108. YUYAMA K, Sun H, Fujii R, Hemmi I, et al
     Extracellular vesicle proteome unveils cathepsin B connection to Alzheimer's disease pathogenesis.
     Brain. 2023 Dec 10:awad361. doi: 10.1093.
     PubMed     Abstract available
     
     
     
109. TARUTANI A, Kametani F, Tahira M, Saito Y, et al
     Distinct tau folds initiate templated seeding and alter the post-translational modification profile.
     Brain. 2023;146:4988-4999.
     PubMed     Abstract available
     
     
     
110. GUBERT C, Hannan AJ
     Microbial manipulation of memories and minds.
     Brain. 2023;146:4791-4793.
     PubMed    
     
     
     November 2023
111. QUESNEL MJ, Labonte A, Picard C, Zetterberg H, et al
     Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains.
     Brain. 2023 Nov 22:awad398. doi: 10.1093.
     PubMed     Abstract available
     
     
     
112. SILVA-RODRIGUEZ J, Labrador-Espinosa MA, Moscoso A, Scholl M, et al
     Characteristics of amnestic patients with hypometabolism patterns suggestive of Lewy body pathology.
     Brain. 2023;146:4520-4531.
     PubMed     Abstract available
     
     
     
113. HAMPEL H, Elhage A, Cho M, Apostolova LG, et al
     Amyloid-related imaging abnormalities (ARIA): radiological, biological and clinical characteristics.
     Brain. 2023;146:4414-4424.
     PubMed     Abstract available
     
     
     
114. RAMANAN VK, Gebre RK, Graff-Radford J, Hofrenning E, et al
     Genetic risk scores enhance the diagnostic value of plasma biomarkers of brain amyloidosis.
     Brain. 2023;146:4508-4519.
     PubMed     Abstract available
     
     
     October 2023
115. GRABRUCKER S, Marizzoni M, Silajdzic E, Lopizzo N, et al
     Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis.
     Brain. 2023 Oct 18:awad303. doi: 10.1093.
     PubMed     Abstract available
     
     
     
116. TUNOLD JA, Tan MMX, Koga S, Geut H, et al
     Lysosomal polygenic risk is associated with the severity of neuropathology in Lewy body disease.
     Brain. 2023;146:4077-4087.
     PubMed     Abstract available
     
     
     
117. KEPP KP, Robakis NK, Hoilund-Carlsen PF, Sensi SL, et al
     The amyloid cascade hypothesis: an updated critical review.
     Brain. 2023;146:3969-3990.
     PubMed     Abstract available
     
     
     
118. DU F, Yu Q, Swerdlow RH, Waites CL, et al
     Glucocorticoid-driven mitochondrial damage stimulates Tau pathology.
     Brain. 2023;146:4378-4394.
     PubMed     Abstract available
     
     
     September 2023
119. COOMANS EM, van Westen D, Pichet Binette A, Strandberg O, et al
     Interactions between vascular burden and amyloid-beta pathology on trajectories of tau accumulation.
     Brain. 2023 Sep 18:awad317. doi: 10.1093.
     PubMed     Abstract available
     
     
     
120. HARDY J, Mummery C
     Reply: Lecanemab: turning point, or status quo? An ethics perspective.
     Brain. 2023;146:e73.
     PubMed    
     
     
     
121. BOCANCEA DI, Svenningsson AL, van Loenhoud AC, Groot C, et al
     Determinants of cognitive and brain resilience to tau pathology: a longitudinal analysis.
     Brain. 2023;146:3719-3734.
     PubMed     Abstract available
     
     
     
122. DALY T
     Lecanemab: turning point, or status quo? An ethics perspective.
     Brain. 2023;146:e71-e72.
     PubMed    
     
     
     
123. COOMANS EM, Tomassen J, Ossenkoppele R, Tijms BM, et al
     Genetically identical twin-pair difference models support the amyloid cascade hypothesis.
     Brain. 2023;146:3735-3746.
     PubMed     Abstract available
     
     
     August 2023
124. KERAMIDIS I, McAllister BB, Bourbonnais J, Wang F, et al
     Restoring neuronal chloride extrusion reverses cognitive decline linked to Alzheimer's disease mutations.
     Brain. 2023 Aug 8:awad250. doi: 10.1093.
     PubMed     Abstract available
     
     
     
125. JUNG Y, Damoiseaux JS
     The potential of blood neurofilament light as a marker of neurodegeneration for Alzheimer's disease.
     Brain. 2023 Aug 4:awad267. doi: 10.1093.
     PubMed     Abstract available
     
     
     
126. WUESTEFELD A, Pichet Binette A, Berron D, Spotorno N, et al
     Age-related and amyloid-beta-independent tau deposition and its downstream effects.
     Brain. 2023;146:3192-3205.
     PubMed     Abstract available
     
     
     
127. RAHAYEL S, Tremblay C, Vo A, Misic B, et al
     Mitochondrial function-associated genes underlie cortical atrophy in prodromal synucleinopathies.
     Brain. 2023;146:3301-3318.
     PubMed     Abstract available
     
     
     
128. MCMILLAN PJ, Benbow SJ, Uhrich R, Saxton A, et al
     Tau-RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change.
     Brain. 2023;146:3206-3220.
     PubMed     Abstract available
     
     
     July 2023
129. GARCIA AM, de Leon J, Tee BL, Blasi DE, et al
     Speech and language markers of neurodegeneration: a call for global equity.
     Brain. 2023 Jul 27:awad253. doi: 10.1093.
     PubMed     Abstract available
     
     
     
130. AKSMAN LM, Oxtoby NP, Scelsi MA, Wijeratne PA, et al
     A data-driven study of Alzheimer's disease related amyloid and tau pathology progression.
     Brain. 2023 Jul 11:awad232. doi: 10.1093.
     PubMed     Abstract available
     
     
     
131. YOUNG AL, Vogel JW, Robinson JL, McMillan CT, et al
     Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies.
     Brain. 2023;146:2975-2988.
     PubMed     Abstract available
     
     
     June 2023
132. 
     Correction to: Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration.
     Brain. 2023 Jun 27:awad208. doi: 10.1093.
     PubMed    
     
     
     
133. VAN DER ENDE EL, In 't Veld SGJG, Hanskamp I, van der Lee S, et al
     CSF proteomics in autosomal dominant Alzheimer's disease highlights parallels with sporadic disease.
     Brain. 2023 Jun 22:awad213. doi: 10.1093.
     PubMed     Abstract available
     
     
     
134. BANERJEE G, Collinge J, Fox NC, Lashley T, et al
     Clinical considerations in early-onset cerebral amyloid angiopathy.
     Brain. 2023 Jun 6:awad193. doi: 10.1093.
     PubMed     Abstract available
     
     
     
135. SCHOONHOVEN DN, Coomans EM, Millan AP, van Nifterick AM, et al
     Tau protein spreads through functionally connected neurons in Alzheimer's disease: a combined MEG/PET study.
     Brain. 2023 Jun 5:awad189. doi: 10.1093.
     PubMed     Abstract available
     
     
     
136. 
     Correction: The most valuable player or the tombstone: is tau the correct target to treat Alzheimer's disease?
     Brain. 2023 Jun 1:awad176. doi: 10.1093.
     PubMed    
     
     
     
137. EDWARDS HM, Wallace CE, Gardiner WD, Doherty BM, et al
     Sex-dependent effects of acute stress on amyloid-beta in male and female mice.
     Brain. 2023;146:2268-2274.
     PubMed     Abstract available
     
     
     
138. ROBINSON JL, Xie SX, Baer DR, Suh E, et al
     Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated.
     Brain. 2023;146:2557-2569.
     PubMed     Abstract available
     
     
     May 2023
139. ZHU M, Xiao B, Xue T, Qin S, et al
     Cdc42GAP deficiency contributes to the Alzheimer's disease phenotype.
     Brain. 2023 May 31:awad184. doi: 10.1093.
     PubMed     Abstract available
     
     
     
140. DAS V, Hajduch M
     Randomizing for Alzheimer's disease drug trials should consider the cancer history of participants.
     Brain. 2023 May 27:awad177. doi: 10.1093.
     PubMed    
     
     
     
141. HARDY J, Mummery C
     Reply: Unblinding in the lecanemab trial in Alzheimer's disease.
     Brain. 2023 May 23:awad201. doi: 10.1093.
     PubMed    
     
     
     
142. VAN GOOL WA
     Unblinding in the lecanemab trial in Alzheimer's disease.
     Brain. 2023 May 18:awad171. doi: 10.1093.
     PubMed    
     
     
     
143. KORETSKY MJ, Alvarado C, Makarious MB, Vitale D, et al
     Genetic risk factor clustering within and across neurodegenerative diseases.
     Brain. 2023 May 16:awad161. doi: 10.1093.
     PubMed     Abstract available
     
     
     
144. JIANG J, Johnson JCS, Requena-Komuro MC, Benhamou E, et al
     Comprehension of acoustically degraded speech in Alzheimer's disease and primary progressive aphasia.
     Brain. 2023 May 15:awad163. doi: 10.1093.
     PubMed     Abstract available
     
     
     
145. YOUNES K, Sha SJ
     The MVP or the tombstone: is tau the correct target to treat Alzheimer's disease?
     Brain. 2023 May 8:awad151. doi: 10.1093.
     PubMed    
     
     
     April 2023
146. GOSSYE H, Van Mossevelde S, Sieben A, Bjerke M, et al
     Patients carrying the mutation p.R406W in MAPT present with non-conforming phenotypic spectrum.
     Brain. 2023;146:1624-1636.
     PubMed     Abstract available
     
     
     
147. PONNUSAMY M, Wang S, Yuksel M, Hansen MT, et al
     Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model.
     Brain. 2023;146:1561-1579.
     PubMed     Abstract available
     
     
     
148. NAM MH, Ko HY, Kim D, Lee S, et al
     Visualizing reactive astrocyte-neuron interaction in Alzheimer's disease using 11C-acetate and 18F-FDG.
     Brain. 2023 Apr 17:awad037. doi: 10.1093.
     PubMed     Abstract available
     
     
     
149. MATTSSON-CARLGREN N, Palmqvist S
     The emerging era of staging Alzheimer's disease pathology using plasma biomarkers.
     Brain. 2023 Apr 6:awad112. doi: 10.1093.
     PubMed    
     
     
     March 2023
150. 
     Correction to: Blood-brain barrier opening of the default mode network in Alzheimer's disease with magnetic resonance-guided focused ultrasound.
     Brain. 2023 Mar 22:awad082. doi: 10.1093.
     PubMed    
     
     
     
151. DONADIO V, Incensi A, Rizzo G, Westermark GT, et al
     Phosphorylated alpha-synuclein in skin Schwann cells: a new biomarker for multiple system atrophy.
     Brain. 2023;146:1065-1074.
     PubMed     Abstract available
     
     
     
152. GREVE HJ, Dunbar AL, Lombo CG, Ahmed C, et al
     The bidirectional lung brain-axis of amyloid-beta pathology: ozone dysregulates the peri-plaque microenvironment.
     Brain. 2023;146:991-1005.
     PubMed     Abstract available
     
     
     February 2023
153. JACK CR, Wiste HJ, Algeciras-Schimnich A, Figdore DJ, et al
     Predicting amyloid PET and tau PET stages with plasma biomarkers.
     Brain. 2023 Feb 15:awad042. doi: 10.1093.
     PubMed     Abstract available
     
     
     September 2022
154. GROOT C, Smith R, Stomrud E, Binette AP, et al
     Phospho-tau with subthreshold tau-PET predicts increased tau accumulation rates in amyloid-positive individuals.
     Brain. 2022 Sep 9. pii: 6695020. doi: 10.1093.
     PubMed     Abstract available
     
     

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