Home The Word Brain	My Amedeo FAQ Privacy About
	Amedeo Chinese For Medical Students & Physicians A complete 20-lesson, 300-page Chinese course with a companion app in 21 languages — free forever. Download the free PDF: Amedeo Chinese PDF

Alzheimer's Disease

Free Subscription 19.10.2026 1 Acta Neuropathol 11 Alzheimers Dement 1 Ann Neurol 1 Biol Psychiatry 3 Curr Alzheimer Res 1 Dement Geriatr Cogn Disord 1 Exp Neurol 21 J Alzheimers Dis 1 Nat Neurosci 5 Neurology 2 Neuropsychology 2 Neuroscience 1 PLoS Biol 1 PLoS One 1 Proc Natl Acad Sci U S A

Retrieve available abstracts of this week’s articles: HTML format

Single Articles

Acta Neuropathol

1. CUSHING BJ, Shahidehpour RK, Abner EL, Jicha GA, et al
   Incident versus prevalent progressive supranuclear palsy: analyses of U.S. Alzheimer's Disease Research Centers data indicate clinical and neuropathological features of a relatively common and underrecognized tauopathy in the aging brain.
   Acta Neuropathol. 2026;152:51.
   PubMed         Abstract available
   
   

   
   Alzheimers Dement

2. BLESSING E
   The right temperature at the right time: A framework for understanding thermoregulatory pathophysiology in Alzheimer's disease.
   Alzheimers Dement. 2026;22:e71847.
   PubMed         Abstract available
   
   
3. VILOR-TEJEDOR N, Rodriguez-Fernandez B, Genius P, Fernandez-Bonet A, et al
   Air pollution is associated with sex-specific longitudinal changes in astrocytic and neuroinflammatory processes linked to cognitive decline in Alzheimer's disease at-risk individuals.
   Alzheimers Dement. 2026;22:e71837.
   PubMed         Abstract available
   
   
4. SCHWEICKART A, Batra R, Huynh K, Blach C, et al
   Sphingolipid and ceramide associations with tau pathology vary across diverse ethnoracial groups in postmortem brain tissue.
   Alzheimers Dement. 2026;22:e71690.
   PubMed         Abstract available
   
   
5. DEVIGNES Q, Pruitt PJ, Petscavage K, Koeppe RA, et al
   Brain microstructure mediates the relationship between Alzheimer's proteinopathies and memory.
   Alzheimers Dement. 2026;22:e71899.
   PubMed         Abstract available
   
   
6. LIU X, de Boer SCM, Tartaglia MC
   Sex-specific brain reserve and progression from mild cognitive impairment to Alzheimer's disease dementia.
   Alzheimers Dement. 2026;22:e71913.
   PubMed         Abstract available
   
   
7. EXALTO LG, van Alphen JL, Barkhof F, Teunissen C, et al
   Dementia with Lewy bodies and amyloid pathology: Eligible for anti-amyloid treatment or not?
   Alzheimers Dement. 2026;22:e71907.
   PubMed         Abstract available
   
   
8. BARTHOLD D, Zissimopoulos J, Basu A, Tysinger B, et al
   The effects of improved access to diabetes medications on risk of Alzheimer's disease and related dementias.
   Alzheimers Dement. 2026;22:e71794.
   PubMed         Abstract available
   
   
9. TALLAPRAGADA B, Galna B, Shishegar R, Markovic SJ, et al
   Data?driven cognitive composites predict Abeta?related decline and progression to MCI: the ADOPIC study.
   Alzheimers Dement. 2026;22:e71917.
   PubMed         Abstract available
   
   
10. LAHLOU S, Ismail Z, Smith EE, Dang-Vu TT, et al
    Vascular brain injury modifies the relationship between sleep duration, cognition, and white matter hyperintensity burden in the Alzheimer's disease continuum.
    Alzheimers Dement. 2026;22:e71838.
    PubMed         Abstract available
    
    
11. SHIFERAW TG, Sarkar S, Baker KM, Wooldridge RS, et al
    ApoE lipidation state directs immunometabolic reprogramming of human microglia.
    Alzheimers Dement. 2026;22:e71882.
    PubMed         Abstract available
    
    
12. DING L, Zheng M, Wang S, Liu W, et al
    Cross-cohort NULISAseq identifies tau-anchored CSF and plasma-specific signatures across the amyloid-positive Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71915.
    PubMed         Abstract available
    
    

    
    Ann Neurol

13. ZIONTZ J, Blazhenets G, Visani A, Chiotis K, et al
    Hemispheric Asymmetry of Neuroimaging Biomarkers in Early Onset Alzheimer's Disease: Clinical and Cognitive Outcomes.
    Ann Neurol. 2026 Oct 14. doi: 10.1002/ana.78391.
    PubMed         Abstract available
    
    

    
    Biol Psychiatry

14. 
    Expression of Concern to: "Gamma Secretase-Activating Protein Is a Substrate for Caspase-3: Implications for Alzheimer's Disease," by Chu et al. (Biol Psychiatry 2015; 77:720-728); https://doi.org/10.1016/j.biopsych.2014.06.003.
    Biol Psychiatry. 2026 Oct 16:S0006-3223(26)01610.
    PubMed        
    
    

    
    Curr Alzheimer Res

15. JIANG Y, Li X, Yue P, Hu Y, et al
    Global Dynamics and Emerging Trends in Alzheimer's Disease and Apoptosis from 2007 to 2025: A Bibliometric Analysis of Scholarly Evolution.
    Curr Alzheimer Res. 2026 Oct 9. doi: 10.2174/0115672050512147260928102334.
    PubMed         Abstract available
    
    
16. LI M, Lv S, Cui L, Fang S, et al
    Tetrachloro-1,4-benzoquinone Exerts Neurotoxicity through Neuroinflammation and the TLR4 Signaling Pathway, which is a Risk Factor for Alzheimer's Disease: An Integrated Network and Mendelian Randomization Analysis.
    Curr Alzheimer Res. 2026 Oct 9. doi: 10.2174/0115672050502048260925094031.
    PubMed         Abstract available
    
    
17. WATSON D, Neam MG, Stafford M, Bouchard C, et al
    Transitioning from Clinical Trial to Clinical Practice for Long-Term Lecanemab Treatment in Early Alzheimer's Disease: Perspectives from a Cohort Study from the Alzheimer's Research and Treatment Center.
    Curr Alzheimer Res. 2026 Oct 12. doi: 10.2174/0115672050525938260923072703.
    PubMed         Abstract available
    
    

    
    Dement Geriatr Cogn Disord

18. HOWE MD, Zide BS, Hayes K, Ross D, et al
    Symptom-Guided Blood Biomarker Testing for Alzheimer's Disease.
    Dement Geriatr Cogn Disord. 2026 Oct 12:1. doi: 10.1159.
    PubMed         Abstract available
    
    

    
    Exp Neurol

19. WAN C, Wang F, Fan Y, Yang Y, et al
    Beyond the brain-centric view: A systems physiology framework for exercise-induced neuroprotection in Alzheimer's disease.
    Exp Neurol. 2026;408:116058.
    PubMed         Abstract available
    
    

    
    J Alzheimers Dis

20. PAN Y, Cho B, Stallings-Smith S
    Sex and racial/ethnic patterns in subjective cognitive concerns-related functional difficulties among middle-aged and older adults: A multi-year cross-sectional analysis of a population-based U.S. adult sample in 2015-2022.
    J Alzheimers Dis. 2026;113:1905-1916.
    PubMed         Abstract available
    
    
21. SHIM Y, Park SK
    APOE epsilon4 genotype-dependent reduction of amyloid-related imaging abnormality in real-world lecanemab use: Implications for risk-stratified prescribing.
    J Alzheimers Dis. 2026;113:1614-1618.
    PubMed         Abstract available
    
    
22. LEE JH, Won GH, Lee SI, Shin CJ, et al
    Cerebrospinal fluid homocysteine, but not plasma homocysteine, is associated with markers of tau pathology and neurodegeneration.
    J Alzheimers Dis. 2026;113:1709-1716.
    PubMed         Abstract available
    
    
23. FU X, Cui M, Yue A, He Q, et al
    Disease-specific hypometabolic epicenters in dementia: Neural networks and clinical correlations.
    J Alzheimers Dis. 2026;113:1745-1757.
    PubMed         Abstract available
    
    
24. SMITASIRI T, Pongpitakmetha T, Thanprasertsuk S, Likitjaroen Y, et al
    Prevalence and impact of cerebral small vessel lesions in mild cognitive impairment and mild dementia due to Alzheimer's disease patients in memory clinic: Preparation for anti-amyloid therapy in Thailand.
    J Alzheimers Dis. 2026 Oct 10:13872877261493065. doi: 10.1177/13872877261493065.
    PubMed         Abstract available
    
    
25. QIAO Y, Chen H, Fan K, Yang X, et al
    High-intensity transcranial alternating current stimulation improves sleep quality in patients with mild Alzheimer's disease: Findings from the TRANSFORM-AD study.
    J Alzheimers Dis. 2026 Oct 10:13872877261492561. doi: 10.1177/13872877261492561.
    PubMed         Abstract available
    
    
26. BEN BRIK S
    Noise or clearance? Reframing plasma amyloid-beta variability in Alzheimer's disease as a measurable clearance signal.
    J Alzheimers Dis. 2026 Oct 10:13872877261496533. doi: 10.1177/13872877261496533.
    PubMed         Abstract available
    
    
27. OZKURT C
    Single-cell gene networks nominate IKZF1 as an Alzheimer's disease microglial regulator.
    J Alzheimers Dis. 2026 Oct 10:13872877261496918. doi: 10.1177/13872877261496918.
    PubMed         Abstract available
    
    
28. TRUONG TD, Shi H, Pena C, Chinnappan B, et al
    Emerging hydrogel platforms for disease modeling, diagnosis, and imaging of Alzheimer's disease.
    J Alzheimers Dis. 2026 Oct 13:13872877261495937. doi: 10.1177/13872877261495937.
    PubMed         Abstract available
    
    
29. ZANTIS A, Uliassi E, Pallara C, Li X, et al
    Integrative analysis of Alzheimer's disease molecular networks with circadian regulators for prioritization of drug repurposing candidates.
    J Alzheimers Dis. 2026 Oct 13:13872877261497407. doi: 10.1177/13872877261497407.
    PubMed         Abstract available
    
    
30. ZHU T, Deng X, Lu J, Zhou X, et al
    The ferroptosis-lipid metabolism-neuroinflammation axis in Alzheimer's disease: A review of mechanistic interplay and therapeutic implications.
    J Alzheimers Dis. 2026 Oct 13:13872877261495962. doi: 10.1177/13872877261495962.
    PubMed         Abstract available
    
    
31. YANG Y, Zhang Y, Meliker JR, Richmond LL, et al
    Education as a proxy for cognitive reserve, and its moderating role in the amyloid-cognition relationship across the Alzheimer's disease continuum: A systematic review and meta-analysis.
    J Alzheimers Dis. 2026 Oct 13:13872877261496419. doi: 10.1177/13872877261496419.
    PubMed         Abstract available
    
    
32. LIU R, Chen J, Xue S, Dong Y, et al
    Effects of aerobic exercise on learning and memory function and inflammatory markers in animal models of Alzheimer's disease: A meta-analysis.
    J Alzheimers Dis. 2026 Oct 13:13872877261496469. doi: 10.1177/13872877261496469.
    PubMed         Abstract available
    
    
33. PYLKKO E, Paakinaho A, Hartikainen S, Kaasinen V, et al
    Identifying drugs associated with Alzheimer's disease risk using machine learning-assisted signal detection.
    J Alzheimers Dis. 2026 Oct 14:13872877261498381. doi: 10.1177/13872877261498381.
    PubMed         Abstract available
    
    
34. NGUYEN N, Huynh S, Mroczko B, Glodzik L, et al
    The role of matrix metalloproteinases in Alzheimer's disease and small vessel disease.
    J Alzheimers Dis. 2026 Oct 14:13872877261494579. doi: 10.1177/13872877261494579.
    PubMed         Abstract available
    
    
35. GIFANI M, Chambers LC, Fernandez Z, Beck JS, et al
    Locus coeruleus degeneration impairs forebrain arteriole physiology and perfusion in a rat model of Alzheimer's disease.
    J Alzheimers Dis. 2026 Oct 16:13872877261496548. doi: 10.1177/13872877261496548.
    PubMed         Abstract available
    
    
36. PETERSON AJ, Sun Y, Liu D, Pechman KR, et al
    Lower cardiac output is associated with longitudinal decreases in cerebrospinal fluid amyloid-beta42, a core Alzheimer's disease biomarker, in women but not men.
    J Alzheimers Dis. 2026 Oct 16:13872877261497236. doi: 10.1177/13872877261497236.
    PubMed         Abstract available
    
    
37. PANDEY JP
    Immunoglobulin GM (gamma marker) allotypes as potential genetic markers of efficacy of lecanemab therapy in Alzheimer's disease.
    J Alzheimers Dis. 2026 Oct 16:13872877261500140. doi: 10.1177/13872877261500140.
    PubMed         Abstract available
    
    
38. MELENDEZ JC, Escudero J, Satorres E, Delhom I, et al
    Home-delivered transcranial direct current stimulation with or without cognitive training in mild dementia due to Alzheimer's disease.
    J Alzheimers Dis. 2026 Oct 16:13872877261498210. doi: 10.1177/13872877261498210.
    PubMed         Abstract available
    
    
39. CHEN C, Huentelman M, Chen K
    Association between handedness and Alzheimer's disease: Results from a large MindCrowd observational study.
    J Alzheimers Dis. 2026 Oct 16:13872877261498845. doi: 10.1177/13872877261498845.
    PubMed         Abstract available
    
    
40. VIDYANTI AN, Prawiroharjo P, Syafrita Y, Prodjohardjono A, et al
    Diagnostic accuracy of plasma amyloid-beta42 and Montreal Cognitive Assessment score as composite index for Alzheimer's disease in resource-limited settings: An exploratory study.
    J Alzheimers Dis. 2026 Oct 16:13872877261497299. doi: 10.1177/13872877261497299.
    PubMed         Abstract available
    
    

    
    Nat Neurosci

41. CAO H, Fu Y, Zhou X, Duan Y, et al
    Genome-wide analysis of common structural variants in Alzheimer's disease identifies a risk-associated regulatory CCG repeat in FAM193B.
    Nat Neurosci. 2026 Oct 12. doi: 10.1038/s41593-026-02481.
    PubMed         Abstract available
    
    

    
    Neurology

42. REYNOLDS EL, Elafros MA, Muthukumar L, Shippey E, et al
    Predictors of Antiamyloid Medication Utilization and Adherence Among People With Alzheimer Disease and Mild Cognitive Impairment.
    Neurology. 2026;107:e218594.
    PubMed         Abstract available
    
    
43. PLANCHE V, Bouteloup V, Pellegrin I, Mangin JF, et al
    Validity and Performance of Blood Biomarkers for Alzheimer Disease to Predict Dementia Risk in a Large Clinic-Based Cohort.
    Neurology. 2026;107:e218790.
    PubMed        
    
    
44. SMITH JR, Pike JR, Lu Y, Walker KA, et al
    Midlife and Late-Life Alzheimer Disease Blood Biomarkers and 11-Year Cognitive Decline.
    Neurology. 2026;107:e218692.
    PubMed         Abstract available
    
    
45. FELICI C, Green RE, Warren-Gash C, Butt J, et al
    Associations of Antibodies Against Several Infections With Alzheimer Disease Neuropathology: A Prospective Cohort Study Analysis.
    Neurology. 2026;107:e218584.
    PubMed         Abstract available
    
    
46. JANG SH, Jung J
    APOE Beyond Alzheimer Disease: Cognitive Aging in the Oldest Old.
    Neurology. 2026;107:e218660.
    PubMed        
    
    

    
    Neuropsychology

47. KEITH CM, Phelps HE, Smith SR, Teixeira CVL, et al
    Motor intrusion errors as a novel marker of neurodegeneration and executive dysfunction in Alzheimer's disease.
    Neuropsychology. 2026 Oct 12. doi: 10.1037/neu0001132.
    PubMed         Abstract available
    
    
48. DI DOMENICO C, Bonarota S, Caruso G, Sperati S, et al
    Retrieval-induced forgetting and facilitation across the Alzheimer's disease continuum: Behavioral and neuroanatomical evidence from a recognition-based paradigm.
    Neuropsychology. 2026 Oct 15. doi: 10.1037/neu0001126.
    PubMed         Abstract available
    
    

    
    Neuroscience

49. SEKIZAR S, Holt K, Meyers S, Tzioras M, et al
    Astrocytic synapse engulfment is differentially controlled by APOE genotype.
    Neuroscience. 2026;616:174-182.
    PubMed         Abstract available
    
    
50. XU W, Cao J, Liu Y, Wei Z, et al
    Corrigendum to "LPI alleviates Alzheimer's disease pathology via the GPR55 receptor" [Neuroscience 611 (2026) 99-110].
    Neuroscience. 2026;618:80.
    PubMed        
    
    

    
    PLoS Biol

51. FFRENCH-CONSTANT C
    Does perturbed adaptive myelination contribute to cognitive dysfunction in Alzheimer's disease?
    PLoS Biol. 2026;24:e3004033.
    PubMed         Abstract available
    
    

    
    PLoS One

52. OTSUKA S, Nakamura Y, Ito-Ishida A, Suzuki K, et al
    Operant House: A versatile open-source platform for automated operant conditioning testing of mice in home cages.
    PLoS One. 2026;21:e0360626.
    PubMed         Abstract available
    
    

    
    Proc Natl Acad Sci U S A

53. ZUSSY C, Mathias M, Vitalis M, Moujellil-Legagneur T, et al
    Shedding light on left hippocampal mGlu5 in Alzheimer's disease.
    Proc Natl Acad Sci U S A. 2026;123:e2535413123.
    PubMed         Abstract available
    
    

Thank you for your interest in scientific medicine.

AMEDEO Alzheimer's Disease is free of charge. Privacy / Datenschutzerklärung | Imprint / Impressum