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  Alzheimer's Disease

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29.09.2025

1 Acta Neuropathol
19 Alzheimers Dement
1 Ann Neurol
1 BMC Neurol
2 Brain
1 Brain Res
1 Dement Geriatr Cogn Disord
1 Exp Gerontol
11 J Alzheimers Dis
2 Neurobiol Dis
1 Neurology
3 Neuroscience
1 PLoS One
1 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. VAN WETERING J, Deshayes NAC, Boone J, Rodrigues Fernandes I, et al
    Limbic Alzheimer's co-pathology in multiple system atrophy is associated with cognitive impairment and diagnostic inaccuracy.
    Acta Neuropathol. 2025;150:30.
    PubMed         Abstract available


    Alzheimers Dement

  2. RAIA T, Cavallaro RA, Borges LDF, Cinti S, et al
    One-carbon metabolism modulates miR-29a-DNA methylation crosstalk in Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70703.
    PubMed         Abstract available

  3. MCDADE EM, Barthelemy NR, Wang G, Li Y, et al
    The relationship of soluble tau species with Alzheimer's disease amyloid plaque removal and tau pathology.
    Alzheimers Dement. 2025;21:e70689.
    PubMed         Abstract available

  4. DAMUKA N, Lockhart SN, Solingapuram Sai KK
    Imaging microtubule dynamics: A new frontier in biomarker development for neurodegenerative diseases.
    Alzheimers Dement. 2025;21:e70670.
    PubMed         Abstract available

  5. ZHOU Y, Liu S, Chen L
    Expanding the horizon of sex-specific proteomic insights in Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70725.
    PubMed        

  6. MEI Z, Wingo AP, Wingo TS
    Response to the letter titled "Expanding the Horizon of Sex-Specific Proteomic Insights in Alzheimer's Disease".
    Alzheimers Dement. 2025;21:e70724.
    PubMed        

  7. CODY KA, Sokolowski A, Guerra LM, Insel PS, et al
    Comparison of amyloid PET acquired through standardized and unstandardized protocols.
    Alzheimers Dement. 2025;21:e70697.
    PubMed         Abstract available

  8. BROWN G, Bustamante-Paytan D, Albujar Pereira MF, Huilca J, et al
    Demographically adjusted normative data among Peruvians with diverse education levels for version 3 of the Alzheimer's Disease Centers' neuropsychological test battery in the Uniform Data Set.
    Alzheimers Dement. 2025;21:e70671.
    PubMed         Abstract available

  9. KLEIMAN MJ, Gibbs G, Joshi MS, Galvin JE, et al
    The Brain Health Index: Integrating vulnerability, resilience, and cognitive function into a unified measure of cognitive health and risk of neurodegenerative disease.
    Alzheimers Dement. 2025;21:e70723.
    PubMed         Abstract available

  10. DEVANARAYAN V, Donohue MC, Sperling RA, Johnson KA, et al
    Multimodal prognostic modeling of individual cognitive trajectories to enhance trial efficiency in preclinical Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70702.
    PubMed         Abstract available

  11. KIVISILD A, Rinnankoski I, Aaltonen M, Aho K, et al
    Sociodemographic traits as early indicators of AD, FTD, and VaD up to 10 years before diagnosis.
    Alzheimers Dement. 2025;21:e70616.
    PubMed         Abstract available

  12. JASODANAND VH, Bellitti M, Kolachalama VB
    An AI-first framework for multimodal data in Alzheimer's disease and related dementias.
    Alzheimers Dement. 2025;21:e70719.
    PubMed         Abstract available

  13. DOECKE JD, Chenna A, Lo M, Badal Y, et al
    Combining Lumipulse p-tau217 and Abeta42/40 as confirmatory tests for Abeta positivity prior to disease-modifying therapy.
    Alzheimers Dement. 2025;21:e70707.
    PubMed         Abstract available

  14. LIU S, Fan S, Gan J, Liao W, et al
    Caregivers' perspectives on lecanemab use for Alzheimer's disease: A national survey in China.
    Alzheimers Dement. 2025;21:e70680.
    PubMed         Abstract available

  15. BOLTON CJ, Zhang P, Nair D, Liu D, et al
    Mild kidney dysfunction affects the predictive accuracy of blood-based biomarkers for neuropsychological and neuroimaging outcomes over a 9 year follow-up period.
    Alzheimers Dement. 2025;21:e70651.
    PubMed         Abstract available

  16. FRANQUESA-MULLERAT M, Morcillo-Nieto AO, Arriola-Infante JE, Zsadanyi SE, et al
    Study of brain perfusion in adults with Down syndrome along the Alzheimer's disease continuum.
    Alzheimers Dement. 2025;21:e70581.
    PubMed         Abstract available

  17. CHAN KCG, Xia F, Kukull WA
    NACC data: Who is represented over time and across centers, and implications for generalizability.
    Alzheimers Dement. 2025;21:e70657.
    PubMed         Abstract available

  18. CHOLERTON BA, Beecham GW, Reitz C, De Vito AN, et al
    Neuropsychiatric symptom subtypes and dementia-associated neuropathologic change.
    Alzheimers Dement. 2025;21:e70622.
    PubMed         Abstract available

  19. GALLEE J, Gibbons LE, Choi SE, Lee M, et al
    Facets of language performance in early-onset and late-onset Alzheimer's disease dementia.
    Alzheimers Dement. 2025;21:e70705.
    PubMed         Abstract available

  20. WELTINGS E, Postema MC, van Dam M, Dubbelman MA, et al
    Everyday functioning in young onset dementia: differences between diagnostic groups.
    Alzheimers Dement. 2025;21:e70711.
    PubMed         Abstract available


    Ann Neurol

  21. ABDELMOITY O, Wisch JK, Kennedy JT, Goyal M, et al
    Cross-Sectional FDG in Down Syndrome and Autosomal Dominant Alzheimer's Disease.
    Ann Neurol. 2025 Sep 22. doi: 10.1002/ana.78002.
    PubMed         Abstract available


    BMC Neurol

  22. ISMAIL YA, Auf HA, Sadik SA, Ahmed NM, et al
    Sensitivity and specificity of the Montreal cognitive assessment using U.S. National alzheimer coordinating centre uniform data set: a retrospective analysis of 16,309 participants.
    BMC Neurol. 2025;25:381.
    PubMed         Abstract available


    Brain

  23. PESCOLLER J, Dewenter A, Dehsarvi A, Steward A, et al
    Cortical tau deposition promotes atrophy in connected white matter regions in Alzheimer's disease.
    Brain. 2025 Sep 12:awaf339. doi: 10.1093.
    PubMed         Abstract available

  24. JOHNSON DR, Wiste HJ, Lowe V, Schwarz CG, et al
    Staging Alzheimer's disease through amyloid and tau PET.
    Brain. 2025 Sep 19:awaf346. doi: 10.1093.
    PubMed         Abstract available


    Brain Res

  25. AKASH A, Ahamed M, Porel P, Aran KR, et al
    Galectin-3 in Alzheimer's disease: pathological roles, biomarker potential, and therapeutic implications.
    Brain Res. 2025 Sep 19:149949. doi: 10.1016/j.brainres.2025.149949.
    PubMed         Abstract available


    Dement Geriatr Cogn Disord

  26. QIAN X, Hong B, Xu Y, Xiao S, et al
    Exploring Modifiable Factors Influencing Agitation in Alzheimer's Disease: A Comprehensive Assessment.
    Dement Geriatr Cogn Disord. 2025 Sep 22:1-22. doi: 10.1159/000548514.
    PubMed         Abstract available


    Exp Gerontol

  27. UCDAL M
    Letter to the editor: Specialized large language models with explainability for Alzheimer's disease diagnosis.
    Exp Gerontol. 2025 Sep 18:112905. doi: 10.1016/j.exger.2025.112905.
    PubMed        


    J Alzheimers Dis

  28. DONG M, Qian Y, Geng Y, Wang R, et al
    HIF-1alpha-induced microglia-mediated neuroinflammation is involved in Alzheimer's disease: Evidence from single-cell transcriptomic analysis.
    J Alzheimers Dis. 2025 Sep 19:13872877251378007. doi: 10.1177/13872877251378007.
    PubMed         Abstract available

  29. SU X, Chen H, Cao J, Zhang Y, et al
    The effect of deprivation of whisker stimulation on cognition and synaptic plasticity in male and female Alzheimer's disease mice.
    J Alzheimers Dis. 2025 Sep 19:13872877251379079. doi: 10.1177/13872877251379079.
    PubMed         Abstract available

  30. GITLIN-LEIGH G, Wilson J, Howard R, Howard R, et al
    Effects of monoclonal antibody therapies on depression in Parkinson's disease and Alzheimer's disease: Systematic review and meta-analysis.
    J Alzheimers Dis. 2025 Sep 19:13872877251378156. doi: 10.1177/13872877251378156.
    PubMed         Abstract available

  31. ONUH VC
    Advancing Alzheimer's disease treatment: A literature review on senolytic intervention.
    J Alzheimers Dis. 2025 Sep 22:13872877251376540. doi: 10.1177/13872877251376540.
    PubMed         Abstract available

  32. SUBRAMANIAN ML, Sampani K, Ness S, Tuz-Zahra F, et al
    Biomarkers for Alzheimer's disease are upregulated in patients with diabetic retinopathy.
    J Alzheimers Dis. 2025 Sep 22:13872877251378759. doi: 10.1177/13872877251378759.
    PubMed         Abstract available

  33. LI J, Yi Y, Gao X, Ren Y, et al
    High brain network dynamics mediate audiovisual integration deficits and cognitive impairment in Alzheimer's disease.
    J Alzheimers Dis. 2025 Sep 22:13872877251376717. doi: 10.1177/13872877251376717.
    PubMed         Abstract available

  34. YAN Y, Pan Y, Lu S, Kou J, et al
    Gut microbiota-mediated targeting of EHMT2 in individuals of European ancestry: A novel therapeutic approach for Alzheimer's disease.
    J Alzheimers Dis. 2025 Sep 22:13872877251372945. doi: 10.1177/13872877251372945.
    PubMed         Abstract available

  35. BOROJE I, Sanchez-Solino O, Yue EX, Vinikoor-Imler L, et al
    Medication prescriptions among patients with mild cognitive impairment and Alzheimer's disease: A large nationwide electronic health record cohort study.
    J Alzheimers Dis. 2025 Sep 22:13872877251376032. doi: 10.1177/13872877251376032.
    PubMed         Abstract available

  36. QI T, Feng Y, Kononenko N, Ising C, et al
    Axonal degeneration and retinal neurovascular dysfunction in the TgF344-AD rat model of Alzheimer's disease.
    J Alzheimers Dis. 2025 Sep 23:13872877251379844. doi: 10.1177/13872877251379844.
    PubMed         Abstract available

  37. NASERRAMEZANI Z, Palizvan MR, Ganji A, Ghazavi A, et al
    Synergistic neuroprotection of chitosan-cannabidiol nanoparticles in a rat model of Alzheimer's disease: Amelioration of cognitive deficits and neuroinflammation.
    J Alzheimers Dis. 2025 Sep 24:13872877251379420. doi: 10.1177/13872877251379420.
    PubMed         Abstract available

  38. FAIZAN ALI M, Ahmad H, Fawzi Hemida M, Faizan Tahir M, et al
    Aging, Alzheimer's disease, and stroke: A 25-year longitudinal analysis of U.S. mortality trends.
    J Alzheimers Dis. 2025 Sep 24:13872877251380689. doi: 10.1177/13872877251380689.
    PubMed         Abstract available


    Neurobiol Dis

  39. STRINGER CA, Miyasato HKS, Camey KA, Ghadia KA, et al
    Regional differences in astrocytic Aquaporin-4 protein levels and distribution in aging and Alzheimer's disease in down syndrome.
    Neurobiol Dis. 2025 Sep 21:107114. doi: 10.1016/j.nbd.2025.107114.
    PubMed         Abstract available

  40. HEAVENER KS, Tamucci KA, Lee AJ, Kabra K, et al
    P2RX7 modulates the function of human microglia-like cells and mediates the association of IL18 with Alzheimer's disease traits.
    Neurobiol Dis. 2025 Sep 21:107106. doi: 10.1016/j.nbd.2025.107106.
    PubMed         Abstract available


    Neurology

  41. TRUDEL L, Therriault J, Macedo AC, Servaes S, et al
    Implication for Clinical Trials From Longitudinal Tau-PET Accumulation Across Biological Alzheimer Disease Stages.
    Neurology. 2025;105:e214111.
    PubMed         Abstract available


    Neuroscience

  42. IQBAL A, Iqbal K, Shah YA, Ullah F, et al
    Multi-filter stacking in inception V3 for enhanced Alzheimer's severity classification.
    Neuroscience. 2025;586:21-31.
    PubMed         Abstract available

  43. ALSHEHRI ZS
    Integrating artificial intelligence with small molecule therapeutics and precision medicine for neurochemical understanding of Alzheimer's diseases.
    Neuroscience. 2025;586:44-57.
    PubMed         Abstract available

  44. CHAUHAN P, Vadia N, Ballal S, Joshi KK, et al
    Decoding the neuroprotective potential of hesperidin: Insights into Alzheimer's disease.
    Neuroscience. 2025 Sep 20:S0306-4522(25)00954.
    PubMed         Abstract available


    PLoS One

  45. ISLAM M, Hasan MJ, Mahdy MRC
    CQ-CNN: A lightweight hybrid classical-quantum convolutional neural network for Alzheimer's disease detection using 3D structural brain MRI.
    PLoS One. 2025;20:e0331870.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  46. BROTT BK, Raissi AJ, Micheva KD, Vielmetter J, et al
    C4d, a high-affinity LilrB2 ligand, is elevated in Alzheimer's disease and mediates synapse pruning.
    Proc Natl Acad Sci U S A. 2025;122:e2519253122.
    PubMed         Abstract available


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