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  Alzheimer's Disease

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15.09.2025

15 Alzheimers Dement
2 BMJ
4 Curr Alzheimer Res
1 Drugs
1 Exp Neurol
11 J Alzheimers Dis
2 J Neurochem
1 J Neurol
1 J Neurol Neurosurg Psychiatry
1 Nat Rev Neurol
1 Neuro Endocrinol Lett
5 Neurobiol Aging
2 Neurobiol Dis
1 Neurochem Res
1 Neurology
1 PLoS One
2 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Alzheimers Dement

  1. JUUL-MADSEN K, Rudolph IM, Gomes JP, Meyer K, et al
    Familial Alzheimer's disease mutation identifies novel role of SORLA in release of neurotrophic exosomes.
    Alzheimers Dement. 2025;21:e70591.
    PubMed         Abstract available

  2. HULS A, Tan Y, Casey E, Li Z, et al
    Metabolic dysregulation in Alzheimer's disease: A brain metabolomics approach.
    Alzheimers Dement. 2025;21:e70528.
    PubMed         Abstract available

  3. NUYTTEN M, Voets M, Debroux E, Princen K, et al
    Randomized phase 2a trial assessing a novel septin molecular glue in Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70537.
    PubMed         Abstract available

  4. RAMIREZ AM, Nasciben LB, Moura S, Coombs L, et al
    Ancestral genomic functional differences in oligodendroglia: implications for Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70593.
    PubMed         Abstract available

  5. WEDEN MM, Frank L, Dick AW, Wang Z, et al
    Investment in Alzheimer's disease research for the next generation of adults with Down syndrome will yield health benefits for future generations.
    Alzheimers Dement. 2025;21:e70348.
    PubMed         Abstract available

  6. WANG Z, Torres K, Foster H, Walker G, et al
    Measuring alignment between the ADRC UDS data elements, FDA, and EHR data standards.
    Alzheimers Dement. 2025;21:e70628.
    PubMed         Abstract available

  7. LEE S, Chun MY, Jang H, Weiner M, et al
    Age-related amyloid beta dynamics modeled with the generalized additive model for location, scale, and shape (GAMLSS) across diverse populations: Cross-sectional trajectories and longitudinal validation.
    Alzheimers Dement. 2025;21:e70675.
    PubMed         Abstract available

  8. POWELL L, Silva D, Kovacevich A, Pillai J, et al
    Understanding brain donation decisions: Predictors of indecision and change over time from the Cleveland Alzheimer's Disease Research Center.
    Alzheimers Dement. 2025;21:e70698.
    PubMed         Abstract available

  9. ALOSCO ML, Morrison M, Au R, Steinberg EG, et al
    Boston University Alzheimer's Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer's disease and related dementias.
    Alzheimers Dement. 2025;21:e70654.
    PubMed         Abstract available

  10. EDWARDS L, Smirnov DS, Thomas KR, Longardner K, et al
    Interactive effects of arterial stiffness and Alzheimer's disease risk on cognitive decline in older adults without dementia.
    Alzheimers Dement. 2025;21:e70632.
    PubMed         Abstract available

  11. MCELIGOT AJ, Xiao C, Do TQ
    Associations between comorbid conditions with mild cognitive impairment and Alzheimer's disease by race-ethnicity and sex based on NACC data.
    Alzheimers Dement. 2025;21:e70650.
    PubMed         Abstract available

  12. OTTOY J, Owsicki N, Bilgel M, Binette AP, et al
    Recent advances in neuroimaging of Alzheimer's disease and related dementias.
    Alzheimers Dement. 2025;21:e70648.
    PubMed         Abstract available

  13. FLOUD S, Hermon C, Whiteley W, Fitzpatrick KE, et al
    Hypertension in pregnancy and in midlife and the risk of dementia: prospective study of 1.3 million UK women.
    Alzheimers Dement. 2025;21:e70595.
    PubMed         Abstract available

  14. PHAN TX, Lee JJ, Siegel JZ, Yu H, et al
    Reduced harm aversion relates to antisocial behaviors and orbitofrontal atrophy in dementia patients.
    Alzheimers Dement. 2025;21:e70623.
    PubMed         Abstract available

  15. VITALI F, Torrandell-Haro G, Arias JC, French SR, et al
    Carotid endarterectomy mitigates Alzheimer's disease and non-Alzheimer's disease dementia risk linked to asymptomatic carotid stenosis.
    Alzheimers Dement. 2025;21:e70674.
    PubMed         Abstract available


    BMJ

  16. BOWIE K
    Alzheimer's blood test could open door to new drugs on the NHS, researchers say.
    BMJ. 2025;390:r1916.
    PubMed        

  17. DYER O
    Injectable Alzheimer's drug lecanemab approved in US for use at home.
    BMJ. 2025;390:r1888.
    PubMed        


    Curr Alzheimer Res

  18. DUTTA A, Phukan BC, Roy R, Bhattacharya P, et al
    Arsenic Exposure Induces Cognitive Impairment in Mice with Increased Acetylcholinesterase Activity and Inflammation in the Cortex and Hippocampus: Implications for Alzheimer's Disease.
    Curr Alzheimer Res. 2025 Sep 8. doi: 10.2174/0115672050390649250904100840.
    PubMed         Abstract available

  19. LEE S, Foo J, Yong Y, Daniel Looi Q, et al
    Network Pharmacology of miR-146a-5p as a Potential Anti-Inflammatory Agent in Preventing Alzheimer's Disease.
    Curr Alzheimer Res. 2025 Sep 3. doi: 10.2174/0115672050383519250825060815.
    PubMed         Abstract available

  20. ZHOU SY, Lin HX, Tang JM, Yao QY, et al
    The Association between the rs6656401 Locus of the CR1 Gene and Structural Alterations of Brain Effects in Han Chinese Patients with Alzheimer's Disease.
    Curr Alzheimer Res. 2025 Sep 4. doi: 10.2174/0115672050397092250823195514.
    PubMed         Abstract available

  21. ALGAZZAWI H, Abujamai J, Alshanberi AM, Satar R, et al
    Role of GSK-3 Inhibition in Alzheimer's Disease Therapy.
    Curr Alzheimer Res. 2025 Sep 5. doi: 10.2174/0115672050400781250904082943.
    PubMed         Abstract available


    Drugs

  22. SMOLLER C, Schiller E, Yamashita K, Silverglate BD, et al
    Current and Emerging Pharmacological Approaches to Agitation in Alzheimer's Disease: A Narrative Review of New and Repurposed Therapies.
    Drugs. 2025 Sep 6. doi: 10.1007/s40265-025-02227.
    PubMed         Abstract available


    Exp Neurol

  23. ONO K, Noguchi-Shinohara M, Yoshita M, Naiki H, et al
    Retraction Notice to "Cerebrospinal fluid of Alzheimer's disease and dementia with Lewy bodies patients enhances -synuclein fibril formation in vitro" [Experimental Neurology 203 (2007) 579-583].
    Exp Neurol. 2025 Sep 10:115456. doi: 10.1016/j.expneurol.2025.115456.
    PubMed        


    J Alzheimers Dis

  24. CHEN H, Guo Y, Zhang Z, Huang W, et al
    Neurovascular coupling dysfunction associated with cognition and glial fibrillary acidic protein along the Alzheimer's disease continuum.
    J Alzheimers Dis. 2025 Sep 12:13872877251375476. doi: 10.1177/13872877251375476.
    PubMed         Abstract available

  25. XU J, Sun A, Yang Y, Shi Y, et al
    Real-world observations on neuroinflammation-related drug responses in Alzheimer's disease.
    J Alzheimers Dis. 2025 Sep 12:13872877251376291. doi: 10.1177/13872877251376291.
    PubMed         Abstract available

  26. KAKKAR A, Singh H, Singh BK, Kumar A, et al
    Neuroinflammation and Alzheimer's disease: Unravelling the molecular mechanisms.
    J Alzheimers Dis. 2025 Sep 12:13872877251374353. doi: 10.1177/13872877251374353.
    PubMed         Abstract available

  27. ZHOU Y, Su T, Yuan M, Li WL, et al
    A new lens on Alzheimer's disease: Insights into the Edinger-Westphal nucleus and its circuits.
    J Alzheimers Dis. 2025 Sep 11:13872877251372587. doi: 10.1177/13872877251372587.
    PubMed         Abstract available

  28. HAYES CA, Odden MC, Thorpe RJ Jr
    Application of modified Poisson regression for risk estimation of major neuropathology outcomes: National Alzheimer's coordinating center.
    J Alzheimers Dis. 2025 Sep 9:13872877251375099. doi: 10.1177/13872877251375099.
    PubMed         Abstract available

  29. KATSUMI Y
    Alterations of the brain functional organization in young-onset Alzheimer's disease: Is it a matter of "time"?
    J Alzheimers Dis. 2025 Sep 9:13872877251375094. doi: 10.1177/13872877251375094.
    PubMed         Abstract available

  30. ARSLAN B, Zetterberg H, Ashton NJ
    Integrating kidney function assessment into the clinical interpretation of plasma Alzheimer's disease biomarkers.
    J Alzheimers Dis. 2025 Sep 9:13872877251375101. doi: 10.1177/13872877251375101.
    PubMed         Abstract available

  31. SCHAFFNER E, Sandoz M, Chatton P, Iglesias K, et al
    Tense production in French-speaking participants with Alzheimer's disease: What about discourse? Contribution of a storytelling-in-sequence task.
    J Alzheimers Dis. 2025 Sep 9:13872877251376028. doi: 10.1177/13872877251376028.
    PubMed         Abstract available

  32. TARAGANO F, Seinhart D, Epstein P, Sylvestre V, et al
    A real-world study on the safety and efficacy of therapeutic plasma exchange in patients with Alzheimer's disease.
    J Alzheimers Dis. 2025 Sep 10:13872877251375430. doi: 10.1177/13872877251375430.
    PubMed         Abstract available

  33. MOTOLESE F, Norata D, Iaccarino G, Sapio E, et al
    Predicting cognitive decline in Alzheimer's disease: A real-life proof-of-principle study on multimodal assessment.
    J Alzheimers Dis. 2025 Sep 10:13872877251376676. doi: 10.1177/13872877251376676.
    PubMed         Abstract available

  34. CHATTERJEE P, Ivanic S, Southon A, McCarthy C, et al
    Real world diagnostic performance of plasma p-tau217 for early-onset Alzheimer's disease in a cognitive disorders tertiary care setting.
    J Alzheimers Dis. 2025 Sep 11:13872877251376694. doi: 10.1177/13872877251376694.
    PubMed         Abstract available


    J Neurochem

  35. MALARTE ML, Chiotis K, Ioannou K, Rodriguez-Vieitez E, et al
    Peripheral Inflammation Is Associated With Greater Neuronal Injury and Lower Episodic Memory Among Late Middle-Aged Adults.
    J Neurochem. 2025;169:e70222.
    PubMed         Abstract available

  36. SMITH ED, Torrellas J, McKenna R, Vo Q, et al
    Acetylation Mimetic and Null Mutations Within the Filament Core of P301L Tau Have Varied Effects on Susceptibility to Seeding and Aggregation.
    J Neurochem. 2025;169:e70221.
    PubMed         Abstract available


    J Neurol

  37. ALMEIDA FC, Santos A, Jesus T, Gauthreaux K, et al
    Amygdala-predominant Lewy bodies associate with cognitive decline and amygdala atrophy in Alzheimer's disease neuropathological change.
    J Neurol. 2025;272:629.
    PubMed         Abstract available


    J Neurol Neurosurg Psychiatry

  38. MAGILL N, Tank R, Ferguson D, Alston D, et al
    Accelerated long-term forgetting as a predictor of clinical onset in presymptomatic autosomal dominant Alzheimer's disease.
    J Neurol Neurosurg Psychiatry. 2025 Sep 9:jnnp-2025-336750.
    PubMed         Abstract available


    Nat Rev Neurol

  39. FYFE I
    A role for lithium in Alzheimer disease.
    Nat Rev Neurol. 2025 Sep 8. doi: 10.1038/s41582-025-01143.
    PubMed        


    Neuro Endocrinol Lett

  40. LIU K
    Circadian Rhythm Disruption and Sleep Disorders in Alzheimer's Disease: Mechanistic Insights and Therapeutic Potentials.
    Neuro Endocrinol Lett. 2025;46:59-69.
    PubMed         Abstract available


    Neurobiol Aging

  41. RICHTER G, Kirsebom BE, Jarholm JA, Palhaugen L, et al
    Comparison of CSF neurofilament light chain and total tau as neurodegeneration markers: Associations with synaptic markers and cognitive outcomes.
    Neurobiol Aging. 2025;155:13-23.
    PubMed         Abstract available

  42. RILEY E, Cicero N, Swallow K, Anderson A, et al
    Blood oxygenation level-dependent responses in neuromodulatory nuclei and their associations with attention and memory across age groups.
    Neurobiol Aging. 2025;155:24-34.
    PubMed         Abstract available

  43. MORADI E, Dahnke R, Imani V, Gaser C, et al
    Integrating plasma, MRI, and cognitive biomarkers for personalized prediction of decline across cognitive domains.
    Neurobiol Aging. 2025;155:53-65.
    PubMed         Abstract available

  44. LEONE R, Kobeleva X
    White matter hyperintensities contribute to early cortical thinning in addition to tau in aging.
    Neurobiol Aging. 2025;155:66-77.
    PubMed         Abstract available

  45. ZIA G, Shahid SS, Yang HC, Gao S, et al
    Longitudinal non-linear changes in the microstructure of the hippocampal subfields in older adults.
    Neurobiol Aging. 2025;155:113-123.
    PubMed         Abstract available


    Neurobiol Dis

  46. ONO K, Noguchi M, Matsumoto Y, Yanase D, et al
    Retraction Notice to "Cerebrospinal fluid of Alzheimer patients promotes beta-amyloid fibril formation in vitro" [Neurobiology of Disease 20 (2005) 233-240].
    Neurobiol Dis. 2025 Sep 11:107087. doi: 10.1016/j.nbd.2025.107087.
    PubMed        

  47. ANTEQUERA D, Vargas T, Ugalde C, Spuch C, et al
    Retraction notice to "Cytoplasmic gelsolin increases mitochondrial activity and reduces Abeta burden in a mouse model of Alzheimer's disease" [Neurobiology of Disease 36 (2009) 42-50].
    Neurobiol Dis. 2025 Sep 11:107088. doi: 10.1016/j.nbd.2025.107088.
    PubMed        


    Neurochem Res

  48. TALIB M, Siddiqui N, Tripathi PN, Chaudhary A, et al
    Correction to: Ameliorative Role of Phosphodiesterase-5 (PDE-5) Inhibitor "Avanafil" Via Modulating cAMP & cGMP Pathway Against Alzheimer's Disease.
    Neurochem Res. 2025;50:289.
    PubMed        


    Neurology

  49. ESTELLER-GAUXAX D, Perez Millan A, Sarto J, Puey R, et al
    alpha-Synuclein Seed Amplifications Assay in a Cohort With Cognitive Impairment: Performance and Interactions With CSF and Plasma Biomarkers.
    Neurology. 2025;105:e214040.
    PubMed         Abstract available


    PLoS One

  50. QI W, Shi Y, Shen S, Wang B, et al
    Integration of wearable devices and artificial intelligence in Alzheimer's disease: A scoping review protocol.
    PLoS One. 2025;20:e0331129.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  51. DONG Z, Yin T, Deng Z, Zou H, et al
    Hybridoma-inspired strategy crafts tailored multifunctional exosomes for precision therapy.
    Proc Natl Acad Sci U S A. 2025;122:e2424547122.
    PubMed         Abstract available

  52. VERDUZCO ESPINOZA AP, Na N, Campanati L, Ngo P, et al
    Microglia-to-neuron signaling links APOE4 and inflammation to enhanced neuronal lipid metabolism and network activity.
    Proc Natl Acad Sci U S A. 2025;122:e2516103122.
    PubMed         Abstract available


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