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25.05.2026

2 Acta Neuropathol
1 Alzheimer Dis Assoc Disord
18 Alzheimers Dement
1 BMC Neurol
2 Curr Alzheimer Res
1 Dement Geriatr Cogn Disord
1 Exp Gerontol
1 Exp Neurol
6 J Alzheimers Dis
1 J Neurochem
2 Nat Med
1 Nat Neurosci
2 Neurobiol Aging
1 Neurobiol Dis
2 Neurochem Res
1 Neurosci Lett
3 Neuroscience
4 PLoS One
1 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. FLORES-AGUILAR L, Zaikos TD, Rivera I, Wright ST, et al
    Frequency of mixed neuropathologies in individuals with down syndrome with and without Alzheimer's dementia.
    Acta Neuropathol. 2026;151:55.
    PubMed         Abstract available

  2. SINGH A, Denkinger MN, Leuzy A, Dieckhoff K, et al
    A plasma protein signature for cerebral amyloid angiopathy.
    Acta Neuropathol. 2026;151:59.
    PubMed         Abstract available


    Alzheimer Dis Assoc Disord

  3. DERESCHUK KJ, Asay CC, Espiridion ED
    Depression and Anxiety in Stroke-Related and Alzheimer Disease-Related Pseudobulbar Affect: A TriNetX Retrospective Cohort Study.
    Alzheimer Dis Assoc Disord. 2026 May 15. doi: 10.1097/WAD.0000000000000727.
    PubMed         Abstract available


    Alzheimers Dement

  4. GOGOLA A, Minhas D, Lopresti B, Snitz B, et al
    Complex interplay of astrogliosis and pathology in preclinical Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71520.
    PubMed         Abstract available

  5. VAN DYCK CH
    Letter to the editor response for: "Schneider LS, Kennedy RE, Cutter G. Caution in interpreting disease-modification claims with lecanemab: selective reporting and causal inference. Alzheimer's & Dementia. 2026".
    Alzheimers Dement. 2026;22:e71485.
    PubMed        

  6. LYU X, Brown CA, Duong MT, Fischer EP, et al
    Uncovering distinct spatiotemporal trajectories of T-N mismatch subtypes with likely co-pathology in Alzheimer's disease using event-based modeling.
    Alzheimers Dement. 2026;22:e71474.
    PubMed         Abstract available

  7. BANIOWSKA MR, Mumford P, Prestia F, Stephan P, et al
    Age-related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome.
    Alzheimers Dement. 2026;22:e71498.
    PubMed         Abstract available

  8. SAEED A, Mckennan C, Clougherty JE, Zhou P, et al
    2-aminobutyrate mediates the impact of air pollution on blood biomarkers of Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71388.
    PubMed         Abstract available

  9. CHATTERJEE A, Alvarez B, Sharma RU, Jonson C, et al
    Evaluating the causal effect of mitochondrial dysfunction on Alzheimer's disease and Parkinson's disease using polygenic risk scores and Mendelian randomization.
    Alzheimers Dement. 2026;22:e71469.
    PubMed         Abstract available

  10. LI ZJ, Yang Z, Zhao D, Qiu YH, et al
    Circulatory pro-CTSD binds brain endothelial LRP1 to trigger its lysosomal degradation leading to amyloid beta clearance deficit in Alzheimer's disease mice.
    Alzheimers Dement. 2026;22:e71494.
    PubMed         Abstract available

  11. KARTHIVASHAN G, Wang S, Wu Q, Dahal A, et al
    Native PLGA nanoparticles attenuate disease pathology via multiple pathways in 5xFAD Alzheimer's model.
    Alzheimers Dement. 2026;22:e71348.
    PubMed         Abstract available

  12. RYBICKI-KLER CI, Brooks IAW, Jedrasiak-Cape I, Deng T, et al
    Reciprocal molecular and cellular cholinergic working memory impairments in Alzheimer's disease model mice.
    Alzheimers Dement. 2026;22:e71490.
    PubMed         Abstract available

  13. YOUNG VM, Wiedner C, Baril AA, Pase MP, et al
    Non-linear associations between sleep duration and plasma p-tau181 in the Framingham Heart Study.
    Alzheimers Dement. 2026;22:e71499.
    PubMed         Abstract available

  14. MARUFF P, Albala B, Harvey D, Saito N, et al
    Remote, unsupervised assessment of cognitive impairment and decline in Alzheimer's disease using the Cogstate Brief Battery in ADNI-3.
    Alzheimers Dement. 2026;22:e71357.
    PubMed         Abstract available

  15. OBERLIN LE, Solis-Urra P, Sewell KR, Collins AM, et al
    Physical activity, aerobic fitness, and AD blood biomarkers: The IGNITE study.
    Alzheimers Dement. 2026;22:e71484.
    PubMed         Abstract available

  16. KONIG A, Troger J, Mallick E, Linz N, et al
    Speech-based digital cognitive assessment for clinical trials: Detecting cognitive impairment stages and AD biomarker relations across European cohorts.
    Alzheimers Dement. 2026;22:e71462.
    PubMed         Abstract available

  17. ZHANG J, Zhang J, Ding J, Zhang X, et al
    Reconstructing cerebral lymphatic clearance: an emerging target in the Alzheimer's disease therapeutic pipeline.
    Alzheimers Dement. 2026;22:e71451.
    PubMed         Abstract available

  18. CHONG CHIE JAK, Persohn SA, Simcox OR, Collins A, et al
    Neurovascular-metabolic dysregulation, metabolic connectomics, and metabolic functional changes in Alzheimer's disease: A preclinical and clinical comparison.
    Alzheimers Dement. 2026;22:e71496.
    PubMed         Abstract available

  19. LANDAU SM, Liu P, Harrison TM, Taggett J, et al
    Elevated AD biomarkers do not explain cognitive performance in a community-recruited clinical trial cohort.
    Alzheimers Dement. 2026;22:e71472.
    PubMed         Abstract available

  20. HAMMERS DB, Foster E, Eloyan A, Thangarajah M, et al
    Cognitive dispersion profiles and prediction of cognitive change in early-onset dementias: Results from LEADS.
    Alzheimers Dement. 2026;22:e71492.
    PubMed         Abstract available

  21. SUTHERLAND GT, Chen A, Nguyen-Hao HT, Mundell H, et al
    How does type 2 diabetes modify the risk of Alzheimer's disease?
    Alzheimers Dement. 2026;22:e71471.
    PubMed         Abstract available


    BMC Neurol

  22. MOORE L, Lund AE, Russell C
    Unawareness of deficits in mild cognitive impairment: a systematic review of its role in progression to Alzheimer's disease.
    BMC Neurol. 2026 May 20. doi: 10.1186/s12883-026-04884.
    PubMed         Abstract available


    Curr Alzheimer Res

  23. HUANG QQ, Zhang XL, He SJ, Zhou YH, et al
    Exploring the Mechanism of Saponins from Panax japonicus in Improving Alzheimer's Disease Based on Network Pharmacology and Molecular Docking.
    Curr Alzheimer Res. 2026 May 9. doi: 10.2174/0115672050471394260327075445.
    PubMed         Abstract available

  24. QASIM R, Tariq Z, Ahmed S, Raza M, et al
    Trends in Cerebrovascular Disease Mortality Among Alzheimer Patients in Older Adults Across the USA: A CDC Wonder Analysis.
    Curr Alzheimer Res. 2026 May 18. doi: 10.2174/0115672050429545260402050204.
    PubMed         Abstract available


    Dement Geriatr Cogn Disord

  25. WU F, Yang C, Wu F, Sun Z, et al
    Knowledge, attitude, and practice toward Alzheimer's disease prevention among middle-aged and elderly individuals: a cross-sectional study.
    Dement Geriatr Cogn Disord. 2026 May 16:1-24. doi: 10.1159/000552507.
    PubMed         Abstract available


    Exp Gerontol

  26. MA J, Yang B, Jiang X, Wang L, et al
    Microglial senescence and epigenetic reprogramming in alzheimer's disease: An immunometabolic perspective.
    Exp Gerontol. 2026 May 16:113177. doi: 10.1016/j.exger.2026.113177.
    PubMed         Abstract available


    Exp Neurol

  27. RAZA SA, Pereira de Almeida P, Farid I, Macha N, et al
    Kallikrein-8 contributes to kallikrein-kinin system dysregulation in Alzheimer's disease.
    Exp Neurol. 2026;403:115834.
    PubMed         Abstract available


    J Alzheimers Dis

  28. GABRIELLI AP, Weidling I, Lysaker CR, Novikova L, et al
    An aging hallmark, Alzheimer's disease, and APOE nexus.
    J Alzheimers Dis. 2026 May 21:13872877261452598. doi: 10.1177/13872877261452598.
    PubMed         Abstract available

  29. WEITZEL M, Walendzik A, Giebel GD, Raszke P, et al
    (Alzheimer's) dementia in adults with Down syndrome in Germany: Administrative prevalence based on a claims data analysis.
    J Alzheimers Dis. 2026 May 15:13872877261449417. doi: 10.1177/13872877261449417.
    PubMed         Abstract available

  30. YOSHIDA K, Saito N, Takahashi R, Ando S, et al
    Inflammation-related miR-155-5p as an APOE epsilon4-modulated biomarker for amyloid pathology in mild cognitive impairment.
    J Alzheimers Dis. 2026;111:878-889.
    PubMed         Abstract available

  31. TIAN Q, Greig EE, Hamwi CM, An Y, et al
    Eye movement features are associated with cognitive and mobility decline.
    J Alzheimers Dis. 2026;111:782-791.
    PubMed         Abstract available

  32. ARWINI A, Kirk A, O'Connell M, Morgan D, et al
    Predictors of long-term care admission in a rural and remote memory clinic.
    J Alzheimers Dis. 2026;111:592-599.
    PubMed         Abstract available

  33. CARBONE E, Scibetta S, Cappella M, Crestini A, et al
    A systematic review on the effects of hypercaloric diet in animal models of Alzheimer's disease.
    J Alzheimers Dis. 2026 May 22:13872877261448495. doi: 10.1177/13872877261448495.
    PubMed         Abstract available


    J Neurochem

  34. ARIYATH A, Arigo FD, Fyfe A, Fernando WMADB, et al
    A High-Throughput Assay for Monitoring and Quantifying Amyloid-beta Accumulation and Clearance in Alzheimer's Disease Cell Models.
    J Neurochem. 2026;170:e70473.
    PubMed         Abstract available


    Nat Med

  35. KAESER SA, Schultz SA, Hofmann A, Hasler LM, et al
    Blood phosphorylated tau elevation as a biomarker in immunoglobulin light chain and transthyretin amyloidosis.
    Nat Med. 2026;32:1676-1681.
    PubMed         Abstract available

  36. LEGAZ A, Moguilner S, Barttfeld P, Cuadros Castro J, et al
    The exposome of brain aging across 34 countries.
    Nat Med. 2026;32:1838-1851.
    PubMed         Abstract available


    Nat Neurosci

  37. SANCHEZ-MOLINA P, Rosmus DD, Brownell D, Meral M, et al
    Spatial proteomic analysis in human Alzheimer's disease brains enables identification of microenvironment-dependent microglial cell states.
    Nat Neurosci. 2026 May 18. doi: 10.1038/s41593-026-02267.
    PubMed         Abstract available


    Neurobiol Aging

  38. BETTCHER BM, Ren S, Wang Y, Carlson NE, et al
    Relation of blood-based inflammation conditional networks to key immune health status and Alzheimer's biomarkers in aging adults.
    Neurobiol Aging. 2026;166:14-28.
    PubMed         Abstract available

  39. RAZAVI A, Hou J, Lin SJ, Zhang C, et al
    Predicted brain-regional gene expression patterns in individuals living with Alzheimer's disease.
    Neurobiol Aging. 2026;166:29-40.
    PubMed         Abstract available


    Neurobiol Dis

  40. HOYT KR, Kyhl T, Halloy NR, Obrietan K, et al
    Cellular- and systems-level profiling of amyloid-beta effects on circadian timing.
    Neurobiol Dis. 2026;224:107389.
    PubMed         Abstract available


    Neurochem Res

  41. TANG H, Peng F, Shi Q, Dai X, et al
    beta-Asarone, Tenuifolin, and YuanZhi Decoction Restore Cognitive Function and Modulate GRIN2B-Associated Autophagy in Alzheimer's Disease.
    Neurochem Res. 2026;51:170.
    PubMed         Abstract available

  42. LI Q, Yang Y, Guo B, Liu X, et al
    Alkaloids from Dendrobium Nobile Lindl Improves Mitochondrial Function by Enhancing the Activity of v-ATPase in APP/PS1 Mice.
    Neurochem Res. 2026;51:171.
    PubMed         Abstract available


    Neurosci Lett

  43. XU X, Wang Q, Wang L, Cheng W, et al
    Indoleamine 2,3-dioxygenase 1 (IDO1) promoted the activation of inflammatory response in the brain tissue of Alzheimer's disease mice by regulating NF-kappaB pathway.
    Neurosci Lett. 2026 May 19:138635. doi: 10.1016/j.neulet.2026.138635.
    PubMed         Abstract available


    Neuroscience

  44. ZAFARI R, Kamroo A, Taherkhani T, Nabizdeh F, et al
    DTI-ALPS index and its association with neuroinflammatory and neurodegenerative biomarkers and tau-PET in Alzheimer's continuum.
    Neuroscience. 2026 May 20:S0306-4522(26)00313.
    PubMed         Abstract available

  45. ISLAM J, Lin FY, Lin CY
    A hybrid CNN-GCN framework for interpretable Alzheimer's disease diagnosis from MRI scans.
    Neuroscience. 2026 May 20:S0306-4522(26)00328.
    PubMed         Abstract available

  46. ROY A, Chhetry S, Deka H, Roy R, et al
    TDP-43: a critical amplifier of Alzheimer's disease beyond amyloid and tau.
    Neuroscience. 2026 May 20:S0306-4522(26)00341.
    PubMed         Abstract available


    PLoS One

  47. GUU TW, Li WJ, Lee SH, Hsu CS, et al
    Facilitating the measurement and treatment of Behavioral and Psychological Symptoms of Dementia (BPSD) and understanding caregiver burden using wearable devices in Rural Taiwan-Protocol for a dyadic feasibility pilot study.
    PLoS One. 2026;21:e0342136.
    PubMed         Abstract available


  48. Editorial Note: Zileuton Improves Memory Deficits, Amyloid and Tau Pathology in a Mouse Model of Alzheimer's Disease with Plaques and Tangles.
    PLoS One. 2026;21:e0349725.
    PubMed        

  49. SIEGEL K, Caban M, Tran E, Meng A, et al
    Memory and thinking problems that aging Latinos in New York City would bring to a doctor's attention.
    PLoS One. 2026;21:e0349635.
    PubMed         Abstract available

  50. KIM M, Choi H, Shim Y, Ryoo N, et al
    Prediction of cognitive impairment through speech data analysis: A comparative evaluation of deep learning models.
    PLoS One. 2026;21:e0349412.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  51. JHALDIYAL A, Kumari M, Guttman LC, Tripathi T, et al
    PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer's disease model.
    Proc Natl Acad Sci U S A. 2026;123:e2525028123.
    PubMed         Abstract available


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