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  Alzheimer's Disease

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08.09.2025

1 Acta Neuropathol
12 Alzheimers Dement
1 Am J Geriatr Psychiatry
1 Brain
3 Brain Res
1 Int J Neurosci
10 J Alzheimers Dis
2 J Biol Chem
1 Nat Med
1 Nat Neurosci
1 Nature
3 Neurobiol Dis
2 Neurologia (Engl Ed)
1 Neurology
3 Neuroscience
1 PLoS Genet
3 PLoS One


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. OGG J, Postupna N, Gibbons LE, Ariza J, et al
    Down syndrome and a presenilin 2 variant: dual genetic risk of Alzheimer's disease.
    Acta Neuropathol. 2025;150:24.
    PubMed         Abstract available


    Alzheimers Dement

  2. SINGH SOLORZANO C, Bonomini C, Rosini S, Passeggia I, et al
    The psychological impact of the disclosure of the diagnosis of Alzheimer's disease on informal caregivers.
    Alzheimers Dement. 2025;21:e70412.
    PubMed         Abstract available

  3. WANG G, Li Y, McDade E, Xiong C, et al
    Clinical progression on CDR-SB(c): Progression-free time at each 0.5 unit level in dominantly inherited and sporadic Alzheimer's disease populations.
    Alzheimers Dement. 2025;21:e70643.
    PubMed         Abstract available

  4. LEE SY, Diaz VE, Emanuel OM, Matusz EF, et al
    Moderating effects of plasma glial fibrillary acidic protein along the Alzheimer's disease continuum.
    Alzheimers Dement. 2025;21:e70626.
    PubMed         Abstract available

  5. TOWNSEND DL, Properzi MJ, Betthauser TJ, Klinger HM, et al
    Estimating the preclinical Alzheimer's disease course with multimodal data.
    Alzheimers Dement. 2025;21:e70658.
    PubMed         Abstract available

  6. PISHVA E, Bertram L, Lunnon K
    Delineating blood DNA methylation biomarkers for Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70646.
    PubMed         Abstract available

  7. ZHANG P, Mao C, Sun A, Yang Y, et al
    Real-world observations of GLP-1 receptor agonists and SGLT-2 inhibitors as potential treatments for Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70639.
    PubMed         Abstract available

  8. ZOU H, Lutz MW, Welsh-Bohmer K, Luo S, et al
    Bayesian integration of longitudinal and survival outcomes in Alzheimer's disease prediction.
    Alzheimers Dement. 2025;21:e70094.
    PubMed         Abstract available

  9. TANG C, Yang J, Lei X, Zhang M, et al
    Unraveling the complexity of neurodegeneration: heterogeneous damage patterns of locus coeruleus and substantia nigra in Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70605.
    PubMed         Abstract available

  10. WANG B, Wang ZX, Lv LM, Wang X, et al
    Tenascin-R aggravates Abeta production in the perforant pathway by regulating Nav1.6 activity in APP/PS1 mice.
    Alzheimers Dement. 2025;21:e70633.
    PubMed         Abstract available

  11. COGSWELL PM, Wiste HJ, Therneau TM, Griswold ME, et al
    Association of plasma Alzheimer's disease biomarkers with cognitive decline in cognitively unimpaired individuals.
    Alzheimers Dement. 2025;21:e70625.
    PubMed         Abstract available

  12. HE D, Xu L, Betthauser T, Van Hulle C, et al
    Automated bimodal pause analysis for acoustic markers of cognitive decline and Alzheimer's disease in connected speech.
    Alzheimers Dement. 2025;21:e70635.
    PubMed         Abstract available

  13. BLUE EE, Broome J, Xue D, Kingston H, et al
    Multi-ancestry meta-analysis identifies genetic modifiers of age-at-onset of Alzheimer's disease at known and novel loci.
    Alzheimers Dement. 2025;21:e70489.
    PubMed         Abstract available


    Am J Geriatr Psychiatry

  14. NGUYEN HT, Nguyen BT, Nguyen PQ, Nguyen BH, et al
    A Screening Protocol to Identify Older Adults With Dementia and Their Family Caregivers in Northern Vietnam.
    Am J Geriatr Psychiatry. 2025;33:1134-1144.
    PubMed         Abstract available


    Brain

  15. YU L, Du L, Wang T, Barnes LL, et al
    Neuropathologic correlates of distinct plasma biomarker profiles in community-living older adults.
    Brain. 2025;148:3340-3349.
    PubMed         Abstract available


    Brain Res

  16. CAM OZUNLU SA, Uysal F, Tatli Dogan H, Parlar A, et al
    Thymoquinone ameliorates cognitive impairment and neuroinflammation in an amyloid-beta-induced rat model of Alzheimer's disease.
    Brain Res. 2025;1866:149918.
    PubMed         Abstract available

  17. GENG D, Liu A, Yan Y, Zheng W, et al
    Intermittent ELF-MF exposure effectively ameliorates pathologic features associated with adult AD mice.
    Brain Res. 2025;1864:149796.
    PubMed         Abstract available

  18. DING Z, Wang J, Ding W, Duan Y, et al
    Calycosin improved long-term memory impairment in the very early of APP/PS1 mice.
    Brain Res. 2025;1864:149789.
    PubMed         Abstract available


    Int J Neurosci

  19. DUAN Q, Liu X, Zhang A
    Effects of simulated presence therapy on agitated behavior, cognition, and use of protective constraint among patients with senile dementia.
    Int J Neurosci. 2025;135:1070-1080.
    PubMed         Abstract available


    J Alzheimers Dis

  20. MOSER VA
    The gap between amyloid pathology and cognition.
    J Alzheimers Dis. 2025;107:46-48.
    PubMed         Abstract available

  21. STROPE TA, Troutwine B, Hauger BM, Smith KP, et al
    Amyloid-beta protein precursor modulates mitophagy and mitochondrial function through its cellular localization.
    J Alzheimers Dis. 2025;107:277-293.
    PubMed         Abstract available

  22. TANG Q, Zhang X, Zhang C, Lang Q, et al
    Optimized sequential classification models for mild cognitive impairment screening based on handwriting and speech data.
    J Alzheimers Dis. 2025;107:112-127.
    PubMed         Abstract available

  23. KRAMER M, Alekseyenko AV, Mollalo A
    The role of built and social environments in Alzheimer's disease dementia prevalence in the United States: A machine learning approach.
    J Alzheimers Dis. 2025 Sep 1:13872877251372144. doi: 10.1177/13872877251372144.
    PubMed         Abstract available

  24. SU FJ, Li YC, Shi XC, Yi C, et al
    Visual Cognitive Assessment Test correlates with brain amyloid status in Alzheimer's disease-related mild cognitive impairment.
    J Alzheimers Dis. 2025 Sep 1:13872877251371718. doi: 10.1177/13872877251371718.
    PubMed         Abstract available

  25. STREIBER AM, Neitzel J, Yaqub A, Vernooij MW, et al
    Arteriosclerosis in the heart-brain axis and Alzheimer's disease plasma markers in the Rotterdam Study.
    J Alzheimers Dis. 2025 Sep 3:13872877251372641. doi: 10.1177/13872877251372641.
    PubMed         Abstract available

  26. JIANG X, Liu Y, Lu Q, Liu J, et al
    Identification of exosome-related genes in Alzheimer's disease: Evidence from transcriptomic and Mendelian randomization analyses.
    J Alzheimers Dis. 2025 Sep 3:13872877251372065. doi: 10.1177/13872877251372065.
    PubMed         Abstract available

  27. ZHU Y, Chen Q, Chen F, Lu J, et al
    Functional connectivity signatures of olfactory networks linked to cognitive risk: A functional MRI study in subjective cognitive decline at risk for Alzheimer's disease.
    J Alzheimers Dis. 2025 Sep 3:13872877251373017. doi: 10.1177/13872877251373017.
    PubMed         Abstract available

  28. LIU G, Sun Y
    Harnessing nanoparticles for Alzheimer's disease: Innovations in drug delivery and pathology-specific treatments.
    J Alzheimers Dis. 2025 Sep 3:13872877251374149. doi: 10.1177/13872877251374149.
    PubMed         Abstract available

  29. WANG L, Zuo X, Xu M, Hu Q, et al
    Interaction between gut microbiota and Alzheimer's disease: Re-analysis of the same sample.
    J Alzheimers Dis. 2025 Sep 4:13872877251367359. doi: 10.1177/13872877251367359.
    PubMed         Abstract available


    J Biol Chem

  30. BLAZIER DM, Lewandowski EM, Ram N, Zhang X, et al
    A biophysical and molecular characterization of the interaction between the Alzheimer risk factor BIN1 and the neuronal scaffold protein p140Cap.
    J Biol Chem. 2025 Aug 30:110665. doi: 10.1016/j.jbc.2025.110665.
    PubMed         Abstract available

  31. NYBERG E, Konings SC, Lindblom N, Israelsson B, et al
    Neuronal endolysosomal alterations induced by Apolipoprotein E4 emerge over time in primary neurons.
    J Biol Chem. 2025;301:110479.
    PubMed         Abstract available


    Nat Med

  32. ALI M, Erabadda B, Chen Y, Xu Y, et al
    Author Correction: Shared and disease-specific pathways in frontotemporal dementia and Alzheimer's and Parkinson's diseases.
    Nat Med. 2025 Sep 2. doi: 10.1038/s41591-025-03970.
    PubMed        


    Nat Neurosci

  33. PAGANO ZOTTOLA AC, Martin-Jimenez R, Lavanco G, Hamel-Cote G, et al
    Potentiation of mitochondrial function by mitoDREADD-G(s) reverses pharmacological and neurodegenerative cognitive impairment in mice.
    Nat Neurosci. 2025;28:1844-1857.
    PubMed         Abstract available


    Nature

  34. KOZLOVA A, Zhang S, Sudwarts A, Zhang H, et al
    PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia.
    Nature. 2025 Sep 3. doi: 10.1038/s41586-025-09486.
    PubMed         Abstract available


    Neurobiol Dis

  35. GIANNELLI S, Eroli F, Loera-Valencia R, Leoni V, et al
    Elevated 24-hydroxycholesterol levels counteract okadaic acid-induced tau hyperphosphorylation and neuronal morphology impairment.
    Neurobiol Dis. 2025;214:107029.
    PubMed         Abstract available

  36. NEU M, Parfentev I, Potts GK, Stoberl N, et al
    A role for the autophagy receptor NBR1 in the degradation of tau aggregates.
    Neurobiol Dis. 2025;214:107060.
    PubMed         Abstract available

  37. WANG Y, Lin J, Qu Y, Ding Y, et al
    Biomarker profile of a Chinese ALS cohort: A comprehensive clinical-biomarkers-imaging analysis.
    Neurobiol Dis. 2025;214:107059.
    PubMed         Abstract available


    Neurologia (Engl Ed)

  38. TORRENTE M, Pino M, Pena-Casanova J
    Development and concurrent validation of a retrogenetic instrument for the assessment of activities of daily living: the functional assessment scale of the Barcelona test.
    Neurologia (Engl Ed). 2025;40:651-660.
    PubMed         Abstract available

  39. GIL-MONTOYA JA, Gerez-Munoz MJ, Trivino-Ibanez E, Carrera-Munoz I, et al
    Periodontal disease and brain amyloid pathology in mild cognitive impairment.
    Neurologia (Engl Ed). 2025;40:641-650.
    PubMed         Abstract available


    Neurology

  40. WANG X, Ye T, Zhou W, Zhang J, et al
    Association of Distinct Initial beta-Amyloid Levels With Tau Pathology Expansion Beyond the Entorhinal Cortex.
    Neurology. 2025;105:e214041.
    PubMed         Abstract available


    Neuroscience

  41. LAYAL H, Rajbongshi J, Kumar R, Pandey S, et al
    Hydrogen sulfide in the brain as a silent neuroprotector in Alzheimer's disease.
    Neuroscience. 2025 Sep 2:S0306-4522(25)00905.
    PubMed         Abstract available

  42. AKAN T, Akan S, Alp S, Ledbetter CR, et al
    AlzFormer: Video-based space-time attention model for early diagnosis of Alzheimer's disease.
    Neuroscience. 2025 Sep 3:S0306-4522(25)00910.
    PubMed         Abstract available

  43. SHENG J, Wang J, Zhang Q, Huang R, et al
    Cognitive prediction using regional connectivities and network biomarkers in Alzheimer's disease.
    Neuroscience. 2025 Sep 3:S0306-4522(25)00907.
    PubMed         Abstract available


    PLoS Genet

  44. LIU S, Bush WS, Akinyemi RO, Byrd GS, et al
    Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review.
    PLoS Genet. 2025;21:e1011701.
    PubMed         Abstract available


    PLoS One

  45. HOSSAIN MM, Adhikari J, Dutta A, Khandaker A, et al
    Computational prediction of high-risk non-synonymous SNPs in human ApoE and their structural impact on amyloid-beta interaction in Alzheimer's disease pathogenesis.
    PLoS One. 2025;20:e0331339.
    PubMed         Abstract available

  46. CAMPANELLI L, Sendoya JM, Brody S, Galeano P, et al
    New insights into the molecular biology of Alzheimer's-like cerebral amyloidosis achieved through multi-omics approaches.
    PLoS One. 2025;20:e0330859.
    PubMed         Abstract available

  47. MARIA, Khan A, Ajaj R, Rauf A, et al
    Secondary metabolites isolated from Fernandoa adenophylla (Wall. ex G.Don) steenis as multitarget inhibitors of cholinesterases for the treatment of Alzheimer's Disease, followed by molecular docking studies.
    PLoS One. 2025;20:e0331119.
    PubMed         Abstract available


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