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Efficacy, Immunogenicity, Safety, and Tolerability of AADvac1 in Alzheimer
Disease: A Systematic Review and Meta-Analysis of Placebo-Controlled Trials.
Alzheimer Dis Assoc Disord. 2025 Aug 18. doi: 10.1097/WAD.0000000000000686.
PubMed
Abstract available
Linkage and association of preserved cognitive function in the midwestern Amish
at a higher genetic risk of Alzheimer's disease.
Alzheimers Dement. 2025;21:e70627.
PubMed
Abstract available
Late-life emergence of neuropsychiatric symptoms and risk of cognitive impairment
in cognitively unimpaired individuals.
Alzheimers Dement. 2025;21:e70619.
PubMed
Abstract available
Cardiovascular contributions to dementia: Examining sex differences and
female-specific factors.
Alzheimers Dement. 2025;21:e70610.
PubMed
Abstract available
MicroRNA-153-3p targets repressor element 1-silencing transcription factor (REST)
and neuronal differentiation: Implications for Alzheimer's disease.
Alzheimers Dement. 2025;21:e70399.
PubMed
Abstract available
Ocular changes as potential biomarkers for early diagnosis of Alzheimer's
disease.
Alzheimers Dement. 2025;21:e70476.
PubMed
Abstract available
Alterations in MRI-visible perivascular spaces precede dementia diagnosis by 18
years in autosomal dominant Alzheimer's disease.
Alzheimers Dement. 2025;21:e70588.
PubMed
Abstract available
Alzheimer's Disease Research Center Down Syndrome Cores: Experience from two
sites.
Alzheimers Dement. 2025;21:e70612.
PubMed
Abstract available
Correction to "Genetic and pharmacologic enhancement of SUMO(2) conjugation
prevents and reverses cognitive impairment and synaptotoxicity in a preclinical
model of Alzheimer's disease".
Alzheimers Dement. 2025;21:e70606.
PubMed
Imaging myelin degradation in ex vivo prefrontal cortex tissue blocks in
Alzheimer's disease and chronic traumatic encephalopathy.
Alzheimers Dement. 2025;21:e70582.
PubMed
Abstract available
Hippocampal tau distribution in primary age-related tauopathy: The Vantaa 85+
Study.
Alzheimers Dement. 2025;21:e70613.
PubMed
Abstract available
Ms4a4a deficiency ameliorates plaque pathology in a mouse model of amyloid
accumulation.
Alzheimers Dement. 2025;21:e70580.
PubMed
Abstract available
Cognitive outcomes of deep brain stimulation depend on age and hippocampal
connectivity in Parkinson's and Alzheimer's disease.
Alzheimers Dement. 2025;21:e70498.
PubMed
Abstract available
ABCA7 deletion lowers age at onset of Alzheimer's disease and interacts with APOE
epsilon4 synergistically in African-ancestry populations.
Alzheimers Dement. 2025;21:e70583.
PubMed
Abstract available
Lipid profiling reveals unsaturated lipid reduction in women with Alzheimer's
disease.
Alzheimers Dement. 2025;21:e70512.
PubMed
Abstract available
A brain-derived tau oligomer polymorph is associated with cognitive resilience to
Alzheimer's disease.
Alzheimers Dement. 2025;21:e70550.
PubMed
Abstract available
Leveraging multiomic approaches to elucidate mechanisms of heterogeneity in
Alzheimer's disease: Neuropsychiatric symptoms, co-pathologies, and sex
differences.
Alzheimers Dement. 2025;21:e70549.
PubMed
Abstract available
Role of (18)F-florzolotau PET in diagnostic and therapeutic decision-making for
cognitive impairment.
Alzheimers Dement. 2025;21:e70563.
PubMed
Abstract available
Developing biobanking processes for Alzheimer's disease and related dementia
research in Africa: Experience from the Recruitment and Retention for Alzheimer's
Disease Diversity in the Alzheimer's Disease Sequencing Project (READD-ADSP).
Alzheimers Dement. 2025;21:e70559.
PubMed
Abstract available
The burden of cognitive impairment.
Alzheimers Dement. 2025;21:e70436.
PubMed
Abstract available
Astrovascular decoupling in awake 5xFAD mice is associated with reduced
astrocytic calcium.
Alzheimers Dement. 2025;21:e70564.
PubMed
Abstract available
Causal effect of conventional anti-dementia drugs on economic burden: an
orthogonal double/debiased machine learning approach.
BMC Geriatr. 2025;25:659.
PubMed
Abstract available
Reproducibility and validity of adapted clinical tests for the assessment of
muscle strength in community-dwelling older adults living with Alzheimer's
disease.
BMC Geriatr. 2025;25:636.
PubMed
Abstract available
Glutamatergic and GABAergic metabolite levels in Alzheimer's disease: a
systematic review and meta-analysis.
BMC Neurol. 2025;25:344.
PubMed
Abstract available
Spearmint extract Neumentix downregulates amyloid-beta accumulation by promoting
phagocytosis in APP23 mice.
Brain Res. 2025;1863:149752.
PubMed
Abstract available
TREM2 R47H variant and risk for Alzheimer's disease: assessment in a Greek
population and updated meta-analysis.
Int J Neurosci. 2024;134:786-794.
PubMed
Abstract available
Impact of antidiabetic therapy on cognitive function in patients with type 2
diabetes and Alzheimer's disease: A comprehensive analysis.
J Alzheimers Dis. 2025 Aug 25:13872877251365662. doi: 10.1177/13872877251365662.
PubMed
Abstract available
Biomarker extraction-based Alzheimer's disease stage detection using optimized
deep learning approach.
J Alzheimers Dis. 2025 Aug 19:13872877251360394. doi: 10.1177/13872877251360394.
PubMed
Abstract available
Revisiting APOE: Insights from rare variants and the expanding landscape of
Alzheimer's disease genetics.
J Alzheimers Dis. 2025 Aug 17:13872877251366662. doi: 10.1177/13872877251366662.
PubMed
Abstract available
Sex differences in the impact of genetic and clinical risk factors for
Alzheimer's disease in midlife.
J Alzheimers Dis. 2025 Aug 17:13872877251366701. doi: 10.1177/13872877251366701.
PubMed
Abstract available
Andrographolide modulates glucose metabolism in visceral adipose tissue in an
Alzheimer's disease obese mouse model.
J Biol Chem. 2025 Aug 16:110607. doi: 10.1016/j.jbc.2025.110607.
PubMed
Abstract available
Common miRNAs, Genes, and Regulatory Pathways in Alzheimer's Disease and Type 2
Diabetes Mellitus: An Integrative Analysis of Systematic Reviews, Bioinformatics
and Data Mining.
J Neurochem. 2025;169:e70196.
PubMed
Abstract available
The HTT gene influences plasma neurofilament light chain and brain metabolism in
prodromal Alzheimer's disease.
J Neurol. 2025;272:588.
PubMed
Abstract available
Glucagon-like peptide-1 receptor agonists for major neurocognitive disorders.
J Neurol Neurosurg Psychiatry. 2025;96:870-883.
PubMed
Abstract available
Disrupted calcium dynamics in reactive astrocytes occur with endfeet-arteriole
decoupling in an amyloid mouse model of Alzheimer's disease.
J Neurosci. 2025 Aug 15:e0349252025. doi: 10.1523/JNEUROSCI.0349-25.2025.
PubMed
Abstract available
Treating Alzheimer Disease With Antiamyloid Therapies-The Real-World Experience
Grows.
JAMA. 2025 Aug 22. doi: 10.1001/jama.2025.14180.
PubMed
Plasma phosphorylated tau for Alzheimer's disease diagnosis.
Lancet Neurol. 2025;24:715-717.
PubMed
Alzheimer's disease in Down syndrome: progress and promise.
Lancet Neurol. 2025;24:717-718.
PubMed
Blood phosphorylated tau for the diagnosis of Alzheimer's disease: a systematic
review and meta-analysis.
Lancet Neurol. 2025;24:740-752.
PubMed
Abstract available
Down syndrome and Alzheimer's disease: insights into biomarkers, clinical
symptoms, and pathology.
Lancet Neurol. 2025;24:753-762.
PubMed
Abstract available
APOE epsilon4 carriers share immune-related proteomic changes across neurodegenerative
diseases.
Nat Med. 2025;31:2590-2601.
PubMed
Abstract available
The Global Neurodegeneration Proteomics Consortium: biomarker and drug target
discovery for common neurodegenerative diseases and aging.
Nat Med. 2025;31:2556-2566.
PubMed
Abstract available
Plasma proteomics links brain and immune system aging with healthspan and
longevity.
Nat Med. 2025;31:2703-2711.
PubMed
Abstract available
Proteogenomic signature of Alzheimer's disease and related dementia risk in
individuals with major depressive disorder.
Nat Ment Health. 2025;3:879-888.
PubMed
Abstract available
Human brain organoids reveal new path for Alzheimer's drugs.
Nature. 2025;644:845.
PubMed
Retinal tau phosphorylation in Alzheimer's disease: A mass spectrometry study.
Neurobiol Dis. 2025;215:107057.
PubMed
Abstract available
Pharmacological Evaluation and In-Silico Study of Sabinene as a Potential
Anti-Alzheimer's Drug in AlCl(3)-Induced Rat Model via BACE-1 and GSK3beta
Modulation.
Neurochem Res. 2025;50:278.
PubMed
Abstract available
Alamandine Rescues Cognitive Impairment and Ameliorates Alzheimer's Disease-Like
Neuropathology in APP/PS1 Mice.
Neurochem Res. 2025;50:277.
PubMed
Abstract available
Cortical Gray Matter Proteins Associated With Cerebral Amyloid Angiopathy in
Community-Dwelling Older Adults: An Autopsy Study.
Neurology. 2025;105:e214024.
PubMed
Abstract available
Association of Enlarged Perivascular Spaces With Early Serum and Neuroimaging
Biomarkers of Alzheimer Disease Pathology.
Neurology. 2025;105:e213836.
PubMed
Abstract available
Integrating MRI Volume and Plasma p-Tau217 for Amyloid Risk Stratification in
Early-Stage Alzheimer Disease.
Neurology. 2025;105:e213954.
PubMed
Abstract available
Mixed Pathologies and Cognitive Outcomes in Persons Considered for Anti-Amyloid
Treatment Eligibility Assessment: A Community-Based Study.
Neurology. 2025;105:e214004.
PubMed
Abstract available
Alzheimer Disease Treatments and Co-Pathologies: But At What Age?
Neurology. 2025;105:e214061.
PubMed
Using the Modified Taylor Complex Figure-Recognition Trial (MTCF-RT) to
differentiate amnestic patients with Alzheimer's disease from patients with
memory deficits due to Parkinson's disease or subcortical ischemic vascular
dementia.
Neuropsychology. 2025 Aug 25. doi: 10.1037/neu0001036.
PubMed
Abstract available
Tropisetron modulates the firing activity of pyramidal and fast-spiking
hippocampal CA1 neurons in a mouse model of Alzheimer's disease.
Neurosci Lett. 2025 Aug 17:138360. doi: 10.1016/j.neulet.2025.138360.
PubMed
Abstract available
Cannabidiol improves learning and memory deficits and alleviates anxiety in
12-month-old SAMP8 mice.
PLoS One. 2025;20:e0296586.
PubMed
Abstract available
Deep learning-based Alzheimer's disease detection using magnetic resonance
imaging and gene expression data.
PLoS One. 2025;20:e0330085.
PubMed
Abstract available
Correction: Peripheral Delivery of a CNS Targeted, Metalo-Protease Reduces Abeta
Toxicity in a Mouse Model of Alzheimer's Disease.
PLoS One. 2025;20:e0330647.
PubMed
Abstract available
Multiplex nodal modularity: A novel network metric for the regional analysis of
amnestic mild cognitive impairment during a working memory binding task.
PLoS One. 2025;20:e0328736.
PubMed
Abstract available
Thank you for your interest in scientific medicine.