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  Alzheimer's Disease

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18.08.2025

5 Alzheimers Dement
1 BMC Geriatr
5 Brain
2 Brain Res
4 Curr Alzheimer Res
1 Exp Neurol
8 J Alzheimers Dis
1 J Biol Chem
1 J Neurochem
1 J Neuropsychol
1 Nature
1 Neurochem Res
1 Neurosci Lett
2 Neuroscience
2 PLoS One
1 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Alzheimers Dement

  1. MONTOLIU-GAYA L, Valeriano-Lorenzo E, Ashton NJ, Lopez-Gonzalez FJ, et al
    Plasma tau biomarkers are distinctly associated with tau tangles and decreased with Lewy body pathology.
    Alzheimers Dement. 2025;21:e70562.
    PubMed         Abstract available

  2. JIN Z, Lu Y, Tang H, Cui H, et al
    Integrating neuroinflammation biomarkers into the ATN(X) framework: Advances in Alzheimer's pathogenesis, diagnosis, and insights from non-human primate models.
    Alzheimers Dement. 2025;21:e70472.
    PubMed         Abstract available

  3. COUSINS KAQ, Korecka M, Wan Y, Vulaj A, et al
    Comparison of plasma p-tau217/Abeta42, p-tau217, and Abeta42/Abeta40 biomarkers by race to detect Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70469.
    PubMed         Abstract available

  4. NA HK, Cho H, Lee HS, Kim HK, et al
    Neural basis of motor symptoms in Alzheimer's disease: role of regional tau burden and cognition.
    Alzheimers Dement. 2025;21:e70598.
    PubMed         Abstract available

  5. HUANG YN, Liu S, Park T, Chaudhuri S, et al
    Plasma proteomic analysis identifies proteins and pathways related to Alzheimer's risk.
    Alzheimers Dement. 2025;21:e70579.
    PubMed         Abstract available


    BMC Geriatr

  6. HOKKINEN K, Dietz A, Lampela P, Hartikainen S, et al
    The incidence of sensorineural hearing loss diagnoses in people with and without Alzheimer's disease - a nationwide cohort study.
    BMC Geriatr. 2025;25:615.
    PubMed         Abstract available


    Brain

  7. BERSON E, Perna A, Bukhari S, Kim Y, et al
    Deep learning-based cell type profiles reveal signatures of Alzheimer's disease resilience and resistance.
    Brain. 2025 Aug 5:awaf285. doi: 10.1093.
    PubMed         Abstract available

  8. M'BRA PEH, Hamilton LK, Moquin-Beaudry G, Mangahas CL, et al
    Medium-chain triglycerides improve cognition and systemic metabolism in mouse models of Alzheimer's disease.
    Brain. 2025 Aug 6:awaf267. doi: 10.1093.
    PubMed         Abstract available

  9. ESPAY AJ, Ezzat K, Kepp KP, Daly T, et al
    Restoring amyloid-beta42 and gamma-secretase function in Alzheimer's disease.
    Brain. 2025 Aug 8:awaf294. doi: 10.1093.
    PubMed         Abstract available

  10. SKELLY D, Attfield KE, Fugger L
    T cells turn in Alzheimer's disease.
    Brain. 2025 Aug 14:awaf288. doi: 10.1093.
    PubMed        

  11. DE BRUIN H, Groot C, Barthel H, Bischof GN, et al
    Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease.
    Brain. 2025 Aug 14:awaf279. doi: 10.1093.
    PubMed         Abstract available


    Brain Res

  12. LIU L, Jiang M, Zhang Y, Lv L, et al
    Acori Tatarinowii Rhizoma inhibited neuroinflammation in Alzheimer's disease rats by modulating the intestinal flora.
    Brain Res. 2025 Aug 8:149878. doi: 10.1016/j.brainres.2025.149878.
    PubMed         Abstract available

  13. LIU B, Ahmad MA, Abbas G, Ahmed U, et al
    From particulates to pathways: environmental exposures and their impact on Alzheimer's disease.
    Brain Res. 2025 Aug 8:149880. doi: 10.1016/j.brainres.2025.149880.
    PubMed         Abstract available


    Curr Alzheimer Res

  14. AMINE JM, Mourad M
    Multimodal Deep Learning Approaches for Early Detection of Alzheimer's Disease: A Comprehensive Systematic Review of Image Processing Techniques.
    Curr Alzheimer Res. 2025 Aug 7. doi: 10.2174/0115672050401817250721190509.
    PubMed         Abstract available

  15. VARSHNEY H, Gaur K, Subhan I, Fatima J, et al
    Neuroprotective Effects of Fenugreek Leaf Extract in a Drosophila Model of Alzheimer's Disease Expressing Human Abeta-42.
    Curr Alzheimer Res. 2025 Aug 7. doi: 10.2174/0115672050385870250721072643.
    PubMed         Abstract available

  16. CHENG W, Zhang J, Zhu H, Wang Z, et al
    NRN1 may Modulate Tau Phosphorylation and Neuronal Apoptosis in AD via the PIGU-CASP3 Axis.
    Curr Alzheimer Res. 2025;22:219-231.
    PubMed         Abstract available

  17. ARAKI W
    Social Isolation as a Risk Factor for Dementia: Insights from Animal Model Studies.
    Curr Alzheimer Res. 2025;22:165-173.
    PubMed         Abstract available


    Exp Neurol

  18. SU WS, Wu MT, Cheng IH, Yang FY, et al
    Low-intensity pulsed ultrasound enhances microglial-mediated Abeta clearance and synaptic preservation in an APP transgenic mouse model of Alzheimer's disease.
    Exp Neurol. 2025 Aug 12:115420. doi: 10.1016/j.expneurol.2025.115420.
    PubMed         Abstract available


    J Alzheimers Dis

  19. MERVOSH N, Bilici N, Wisniewski T, Devi G, et al
    Reducing ARIA risk in Alzheimer's disease: Real-world impact of APOE genotype-guided slow titration with aducanumab and lecanemab.
    J Alzheimers Dis. 2025 Aug 13:13872877251366657. doi: 10.1177/13872877251366657.
    PubMed         Abstract available

  20. XIE F, Ye Y, Hao J, Liu H, et al
    Surgical advances in the treatment of Alzheimer's disease: A comprehensive review.
    J Alzheimers Dis. 2025 Aug 13:13872877251364397. doi: 10.1177/13872877251364397.
    PubMed         Abstract available

  21. ZHANG X, Sun Z, Wu D, Shi X, et al
    Effects of cerebellar intermittent theta-burst stimulation on patients with Alzheimer's disease: A randomized controlled trial.
    J Alzheimers Dis. 2025 Aug 13:13872877251366656. doi: 10.1177/13872877251366656.
    PubMed         Abstract available

  22. PFLANZER H, Kerns KA, Knoble J, Gershon BS, et al
    Mitochondrial energy production genes affecting reactive oxygen species and ATP synthesis, inflammatory pathways, and neuron viability are differentially expressed in brains of Alzheimer's disease patients.
    J Alzheimers Dis. 2025 Aug 13:13872877251362884. doi: 10.1177/13872877251362884.
    PubMed         Abstract available

  23. JIANG F, Wang N, Meng Q
    From APOE to cellular changes: Unraveling the multidimensional mechanisms of blood-brain barrier damage in Alzheimer's disease.
    J Alzheimers Dis. 2025 Aug 13:13872877251360321. doi: 10.1177/13872877251360321.
    PubMed         Abstract available

  24. SHELTON M, Kerns KA, Shirali S, Castora FJ, et al
    Integrating mitochondrial gene expression data to model the effects of respirasome supercomplex formation on reactive oxygen species production in Alzheimer's disease models.
    J Alzheimers Dis. 2025 Aug 13:13872877251362889. doi: 10.1177/13872877251362889.
    PubMed         Abstract available

  25. GHOSH D, Pal S, Lutz M, Luo S, et al
    Ensemble survival analysis for preclinical cognitive decline prediction in Alzheimer's disease using longitudinal biomarkers.
    J Alzheimers Dis. 2025 Aug 14:13872877251365621. doi: 10.1177/13872877251365621.
    PubMed         Abstract available

  26. MOTAGHI M, Potvin O, Duchesne S
    Commonalities in cortical neurodegeneration between type 2 diabetes and Alzheimer's disease.
    J Alzheimers Dis. 2025 Aug 10:13872877251365671. doi: 10.1177/13872877251365671.
    PubMed         Abstract available


    J Biol Chem

  27. WU J, Chai K, Tu Y, Fang K, et al
    Multifunctional Molecular Agent for Tau-targeted Combinational Therapy of Alzheimer's Disease.
    J Biol Chem. 2025 Aug 12:110583. doi: 10.1016/j.jbc.2025.110583.
    PubMed         Abstract available


    J Neurochem

  28. BUCCI M, Almkvist O, Bluma M, Ashton NJ, et al
    Profiling Plasma Biomarkers, Particularly pTau217 and pTau217/Abeta42, and Their Relation to Cognition in Memory Clinic Patients.
    J Neurochem. 2025;169:e70182.
    PubMed         Abstract available


    J Neuropsychol

  29. ILARDI CR
    Clinimetrics: Towards a diagnostic neuropsychology grounded in Alzheimer's disease.
    J Neuropsychol. 2025 Aug 13. doi: 10.1111/jnp.70008.
    PubMed         Abstract available


    Nature

  30. SMITH J
    Daily briefing: Lithium supplements reverse Alzheimer's symptoms in mice.
    Nature. 2025 Aug 7. doi: 10.1038/d41586-025-02559.
    PubMed        


    Neurochem Res

  31. TALIB M, Siddiqui N, Tripathi PN, Chaudhary A, et al
    Ameliorative Role of Phosphodiesterase-5 (PDE-5) Inhibitor "Avanafil" via Modulating cAMP & cGMP Pathway Against Alzheimer's Disease.
    Neurochem Res. 2025;50:258.
    PubMed         Abstract available


    Neurosci Lett

  32. MAURICE T
    Prevention of memory impairment and hippocampal injury with blarcamesine in an Alzheimer's disease model.
    Neurosci Lett. 2025 Aug 8:138349. doi: 10.1016/j.neulet.2025.138349.
    PubMed         Abstract available


    Neuroscience

  33. YANG Y, Ji Q, Cao JJ, Zhang YJ, et al
    Overactivation of the inward rectifier K(+) channel 2.1 modulates intrinsic excitability of adult-born granule cells in the male Alzheimer's APP/PS1 mouse model.
    Neuroscience. 2025 Aug 9:S0306-4522(25)00845.
    PubMed         Abstract available

  34. BARROSO DE SOUSA D, Clara Ribeiro Zucato HM, Ribeiro HM, Alexandre-Silva V, et al
    Interplay between depressive symptoms and Alzheimer's disease dementia: unraveling the potential roles of ADAM10 and Negr1.
    Neuroscience. 2025 Aug 12:S0306-4522(25)00848.
    PubMed         Abstract available


    PLoS One

  35. ZUSCHNEGG J, Ropele S, Opriessnig P, Schmidt R, et al
    The effect of tablet-based multimodal training on cognitive functioning in Alzheimer's disease: A randomized controlled trial.
    PLoS One. 2025;20:e0329931.
    PubMed         Abstract available

  36. BRIDGEFORD EW, Chung J, Anderson RJ, Mahzarnia A, et al
    Network biomarkers of Alzheimer's disease risk derived from joint volume and texture covariance patterns in mouse models.
    PLoS One. 2025;20:e0327118.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  37. FRUITMAN DAVIDI A, Shirenova S, Michaelovich D, Benedetti G, et al
    Dural ectopic lymphatic structures accumulate during aging and exhibit dysregulation in neurodegenerative diseases.
    Proc Natl Acad Sci U S A. 2025;122:e2425081122.
    PubMed         Abstract available


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