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  Alzheimer's Disease

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14.06.2021

9 Alzheimers Dement
1 Am J Alzheimers Dis Other Demen
2 Am J Geriatr Psychiatry
1 BMC Geriatr
1 BMJ
1 Brain
3 Curr Alzheimer Res
2 Dement Geriatr Cogn Disord
5 Exp Gerontol
17 J Alzheimers Dis
1 J Biol Chem
1 J Clin Psychiatry
1 J Neurol Neurosurg Psychiatry
2 JAMA
2 Nature
3 Neurobiol Aging
1 Neurobiol Dis
3 Neurology
2 Neurosci Lett
1 PLoS Biol
2 Proc Natl Acad Sci U S A
1 Science


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Alzheimers Dement

  1. BIRKENBIHL C, Salimi Y, Frohlich H
    Unraveling the heterogeneity in Alzheimer's disease progression across multiple cohorts and the implications for data-driven disease modeling.
    Alzheimers Dement. 2021 Jun 9. doi: 10.1002/alz.12387.
    PubMed         Abstract available

  2. O'BRYANT SE, Zhang F, Petersen M, Hall JR, et al
    A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research.
    Alzheimers Dement. 2021 May 31. doi: 10.1002/alz.12382.
    PubMed         Abstract available

  3. RICHARD E, den Brok MGHE, van Gool WA
    Bayes analysis supports null hypothesis of anti-amyloid beta therapy in Alzheimer's disease.
    Alzheimers Dement. 2021;17:1051-1055.
    PubMed         Abstract available

  4. PANNUZZO M
    Beta-amyloid pore linked to controlled calcium influx into the cell: A new paradigm for Alzheimer's Disease.
    Alzheimers Dement. 2021 May 29. doi: 10.1002/alz.12373.
    PubMed         Abstract available

  5. SCHWAHN C, Frenzel S, Holtfreter B, Van der Auwera S, et al
    Effect of periodontal treatment on preclinical Alzheimer's disease-Results of a trial emulation approach.
    Alzheimers Dement. 2021 May 29. doi: 10.1002/alz.12378.
    PubMed         Abstract available

  6. LOPEZ-RODRIGUEZ AB, Hennessy E, Murray CL, Nazmi A, et al
    Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1beta drives amplified responses in primed astrocytes and neuronal network dysfunction.
    Alzheimers Dement. 2021 Jun 3. doi: 10.1002/alz.12341.
    PubMed         Abstract available

  7. FRANZMEIER N, Ossenkoppele R, Brendel M, Rubinski A, et al
    The BIN1 rs744373 Alzheimer's disease risk SNP is associated with faster Abeta-associated tau accumulation and cognitive decline.
    Alzheimers Dement. 2021 Jun 1. doi: 10.1002/alz.12371.
    PubMed         Abstract available

  8. TEMP AGM, Lutz MW, Trepel D, Tang Y, et al
    How Bayesian statistics may help answer some of the controversial questions in clinical research on Alzheimer's disease.
    Alzheimers Dement. 2021;17:917-919.
    PubMed        

  9. SEXTON CE, Anstey KJ, Baldacci F, Barnum CJ, et al
    Alzheimer's disease research progress in Australia: The Alzheimer's Association International Conference Satellite Symposium in Sydney.
    Alzheimers Dement. 2021 May 31. doi: 10.1002/alz.12380.
    PubMed         Abstract available


    Am J Alzheimers Dis Other Demen

  10. LU L, Dai WZ, Zhu XC, Ma T, et al
    Analysis of Serum miRNAs in Alzheimer's Disease.
    Am J Alzheimers Dis Other Demen. 2021;36:15333175211021712.
    PubMed         Abstract available


    Am J Geriatr Psychiatry

  11. DEVANAND DP, Crocco E, Forester BP, Husain MM, et al
    Low Dose Lithium Treatment of Behavioral Complications in Alzheimer's Disease: Lit-AD Randomized Clinical Trial.
    Am J Geriatr Psychiatry. 2021 May 12. pii: S1064-7481(21)00312.
    PubMed         Abstract available

  12. LEE YM, Park JM, Lee BD, Moon E, et al
    The Role of Decreased Cortical Thickness and Volume of Medial Temporal Lobe Structures in Predicting Incident Psychosis in Patients With Alzheimer's Disease: A Prospective Longitudinal MRI Study.
    Am J Geriatr Psychiatry. 2021 Apr 30. pii: S1064-7481(21)00313.
    PubMed         Abstract available


    BMC Geriatr

  13. SNOW AL, Loup J, Morgan RO, Richards K, et al
    Enhancing sleep quality for nursing home residents with dementia: a pragmatic randomized controlled trial of an evidence-based frontline huddling program.
    BMC Geriatr. 2021;21:281.
    PubMed         Abstract available


    BMJ

  14. MAHASE E
    FDA approves controversial Alzheimer's drug despite uncertainty over effectiveness.
    BMJ. 2021;373:n1462.
    PubMed        


    Brain

  15. SCHUMACHER J, Gunter JL, Przybelski SA, Jones DT, et al
    Dementia with Lewy bodies: association of Alzheimer pathology with functional connectivity networks.
    Brain. 2021 Jun 11. pii: 6296589. doi: 10.1093.
    PubMed         Abstract available


    Curr Alzheimer Res

  16. BURGALETTO C, Benedetto GD, Munafo A, Bernardini R, et al
    Beneficial Effects of Choline Alphoscerate on Amyloid-beta Neurotoxicity in an In vitro Model of Alzheimer's Disease.
    Curr Alzheimer Res. 2021 Jun 7. pii: CAR-EPUB-116013.
    PubMed         Abstract available

  17. PEREZ-SANCHEZ MDC, Gonzalez-Nosti M, Cuetos F, Martinez C, et al
    Reading Fluency in Spanish Patients with Alzheimer's Disease.
    Curr Alzheimer Res. 2021 Jun 7. pii: CAR-EPUB-116019.
    PubMed         Abstract available

  18. MAO C, Li J, Dong L, Huang X, et al
    Clinical Phenotype and Mutation Spectrum of Alzheimer's Disease with Causative Genetic Mutation in a Chinese Cohort.
    Curr Alzheimer Res. 2021 Jun 8. pii: CAR-EPUB-116036.
    PubMed         Abstract available


    Dement Geriatr Cogn Disord

  19. UNDA SR, Antoniazzi AM, Altschul DJ, Marongiu R, et al
    Peripheral Leukocytosis Predicts Cognitive Decline but Not Behavioral Disturbances: A Nationwide Study of Alzheimer's and Parkinson's Disease Patients.
    Dement Geriatr Cogn Disord. 2021 May 31:1-10. doi: 10.1159/000516340.
    PubMed         Abstract available

  20. KUMAI K, Kawabata N, Meguro K, Takada J, et al
    Mental and Physical Self-Awareness of Alzheimer Patients: Decreased Awareness of Amnesia and Increased Fear of Falling Compared to Views of Families: The Tajiri and Wakuya Projects.
    Dement Geriatr Cogn Disord. 2021 Jun 8:1-6. doi: 10.1159/000516656.
    PubMed         Abstract available


    Exp Gerontol

  21. PINI L, Wennberg AM
    Structural imaging outcomes in subjective cognitive decline: Community vs. clinical-based samples.
    Exp Gerontol. 2021;145:111216.
    PubMed         Abstract available

  22. YANG I, Arthur RA, Zhao L, Clark J, et al
    The oral microbiome and inflammation in mild cognitive impairment.
    Exp Gerontol. 2021;147:111273.
    PubMed         Abstract available

  23. LIU L, Cao J, Huang C, Yuan E, et al
    Analysis the alteration of systemic inflammation in old and young APP/PS1 mouse.
    Exp Gerontol. 2021;147:111274.
    PubMed         Abstract available

  24. VATANABE IP, Pedroso RV, Manzine PR, Chagas MHN, et al
    ADAM10: Biomarker of mild cognitive impairment but not of cognitive frailty.
    Exp Gerontol. 2021;149:111303.
    PubMed         Abstract available

  25. EGASHIRA R, Umezaki Y, Mizutani S, Obata T, et al
    Relationship between cerebral atrophy and number of present teeth in elderly individuals with cognitive decline.
    Exp Gerontol. 2021;144:111189.
    PubMed         Abstract available


    J Alzheimers Dis


  26. Clinical Approach of Low-Dose Whole-Brain Ionizing Radiation Treatment in Alzheimer's Disease Dementia Patients.
    J Alzheimers Dis. 2021;81:1343.
    PubMed        

  27. LAURIOLA M, D'Onofrio G, Ciccone F, Germano C, et al
    Relationship of Homocysteine Plasma Levels with Mild Cognitive Impairment, Alzheimer's Disease, Vascular Dementia, Psychobehavioral, and Functional Complications.
    J Alzheimers Dis. 2021 May 20. pii: JAD210166. doi: 10.3233/JAD-210166.
    PubMed         Abstract available

  28. DELAZER M, Zamarian L, Djamshidian A
    Handwriting in Alzheimer's Disease.
    J Alzheimers Dis. 2021 May 28. pii: JAD210279. doi: 10.3233/JAD-210279.
    PubMed         Abstract available

  29. LI X, Tian Y, Yang YX, Ma YH, et al
    Life Course Adiposity and Alzheimer's Disease: A Mendelian Randomization Study.
    J Alzheimers Dis. 2021 May 20. pii: JAD210345. doi: 10.3233/JAD-210345.
    PubMed         Abstract available

  30. BABIC LEKO M, Jurasovic J, Nikolac Perkovic M, Spanic E, et al
    The Association of Essential Metals with APOE Genotype in Alzheimer's Disease.
    J Alzheimers Dis. 2021 May 27. pii: JAD210158. doi: 10.3233/JAD-210158.
    PubMed         Abstract available

  31. THOMSEN BB, Madsen C, Krohn KT, Thygesen C, et al
    Mild Microglial Responses in the Cortex and Perivascular Macrophage Infiltration in Subcortical White Matter in Dogs with Age-Related Dementia Modelling Prodromal Alzheimer's Disease.
    J Alzheimers Dis. 2021 May 26. pii: JAD210040. doi: 10.3233/JAD-210040.
    PubMed         Abstract available

  32. WEI W, Liu Y, Dai C, Baazaoui N, et al
    Neurotrophic Treatment Initiated During Early Postnatal Development Prevents the Alzheimer-Like Behavior and Synaptic Dysfunction.
    J Alzheimers Dis. 2021 May 27. pii: JAD201599. doi: 10.3233/JAD-201599.
    PubMed         Abstract available

  33. YANG H, Luo Y, Hu Q, Tian X, et al
    Benefits in Alzheimer's Disease of Sensory and Multisensory Stimulation.
    J Alzheimers Dis. 2021 May 20. pii: JAD201554. doi: 10.3233/JAD-201554.
    PubMed         Abstract available

  34. KING-ROBSON J, Wilson H, Politis M
    Associations Between Amyloid and Tau Pathology, and Connectome Alterations, in Alzheimer's Disease and Mild Cognitive Impairment.
    J Alzheimers Dis. 2021 May 22. pii: JAD201457. doi: 10.3233/JAD-201457.
    PubMed         Abstract available

  35. JEONG W, Joo JH, Kim H, Kim YK, et al
    Association Between the Use of Hypnotics and the Risk of Alzheimer's Disease.
    J Alzheimers Dis. 2021 May 27. pii: JAD201319. doi: 10.3233/JAD-201319.
    PubMed         Abstract available

  36. GRECO FA, McKee AC, Kowall NW, Hanlon EB, et al
    Near-Infrared Optical Spectroscopy In Vivo Distinguishes Subjects with Alzheimer's Disease from Age-Matched Controls.
    J Alzheimers Dis. 2021 Jun 1. pii: JAD201021. doi: 10.3233/JAD-201021.
    PubMed         Abstract available

  37. BEN AYED I, Castor-Guyonvarch N, Amimour S, Naija S, et al
    Acute Exercise and Cognitive Function in Alzheimer's Disease.
    J Alzheimers Dis. 2021 Jun 1. pii: JAD201317. doi: 10.3233/JAD-201317.
    PubMed         Abstract available

  38. SPERA V, Sitnikova T, Ward MJ, Farzam P, et al
    Pilot Study on Dose-Dependent Effects of Transcranial Photobiomodulation on Brain Electrical Oscillations: A Potential Therapeutic Target in Alzheimer's Disease.
    J Alzheimers Dis. 2021 Jun 3. pii: JAD210058. doi: 10.3233/JAD-210058.
    PubMed         Abstract available

  39. JIN N, Babiloni C, Drinkenburg WH, Hajos M, et al
    Recommendations for Preclinical Testing of Treatments Against Alzheimer's Disease-Related Epileptiform Spikes in Transgenic Rodent Models.
    J Alzheimers Dis. 2021 May 29. pii: JAD210209. doi: 10.3233/JAD-210209.
    PubMed         Abstract available

  40. ZHAO X, Li C, Ding G, Heng Y, et al
    The Burden of Alzheimer's Disease Mortality in the United States, 1999-2018.
    J Alzheimers Dis. 2021 Jun 3. pii: JAD210225. doi: 10.3233/JAD-210225.
    PubMed         Abstract available

  41. SCHOEMAKER D, Velilla L, Zuluaga Y, Baena A, et al
    Global Cardiovascular Risk Profile and Cerebrovascular Abnormalities in Presymptomatic Individuals with CADASIL or Autosomal Dominant Alzheimer's Disease.
    J Alzheimers Dis. 2021 Jun 3. pii: JAD210313. doi: 10.3233/JAD-210313.
    PubMed         Abstract available

  42. VECCHIO F, Miraglia F, Alu F, Orticoni A, et al
    Contribution of Graph Theory Applied to EEG Data Analysis for Alzheimer's Disease versus Vascular Dementia Diagnosis.
    J Alzheimers Dis. 2021 Jun 3. pii: JAD210394. doi: 10.3233/JAD-210394.
    PubMed         Abstract available


    J Biol Chem

  43. BOCHAROVA O, Pandit NP, Molesworth K, Fisher A, et al
    Alzheimer's disease-associated beta-Amyloid does not protect against Herpes Simplex Virus 1 infection in the mouse brain.
    J Biol Chem. 2021 May 27:100845. doi: 10.1016/j.jbc.2021.100845.
    PubMed         Abstract available


    J Clin Psychiatry

  44. BURKE AD
    Can Emerging Therapies Resolve Unmet Needs With Current Treatment in Early-Stage Alzheimer Disease?
    J Clin Psychiatry. 2021;82.
    PubMed         Abstract available


    J Neurol Neurosurg Psychiatry

  45. CHEUNG CY, Mok V, Foster PJ, Trucco E, et al
    Retinal imaging in Alzheimer's disease.
    J Neurol Neurosurg Psychiatry. 2021 Jun 9. pii: jnnp-2020-325347.
    PubMed         Abstract available


    JAMA

  46. CHEN MH, Yang FC, Liang CS
    APOE Allele Testing and Alzheimer Disease.
    JAMA. 2021;325:2210-2211.
    PubMed        

  47. CHOUDHURY P, Ramanan VK, Boeve BF
    APOE Allele Testing and Alzheimer Disease-Reply.
    JAMA. 2021;325:2211.
    PubMed        


    Nature

  48. GRAHAM F
    Daily briefing: Alzheimer's drug controversially approved by FDA.
    Nature. 2021 Jun 8. pii: 10.1038/d41586-021-01553.
    PubMed        

  49. MULLARD A
    Landmark Alzheimer's drug approval confounds research community.
    Nature. 2021 Jun 8. pii: 10.1038/d41586-021-01546.
    PubMed        


    Neurobiol Aging

  50. GAUBERT S, Houot M, Raimondo F, Ansart M, et al
    A machine learning approach to screen for preclinical Alzheimer's disease.
    Neurobiol Aging. 2021;105:205-216.
    PubMed         Abstract available

  51. TSAKIRI EN, Gumeni S, Manola MS, Trougakos IP, et al
    Amyloid toxicity in a Drosophila Alzheimer's model is ameliorated by autophagy activation.
    Neurobiol Aging. 2021;105:137-147.
    PubMed         Abstract available

  52. BOSSAERTS L, Hens E, Hanseeuw B, Vandenberghe R, et al
    Premature termination codon mutations in ABCA7 contribute to Alzheimer's disease risk in Belgian patients.
    Neurobiol Aging. 2021 May 2. pii: S0197-4580(21)00146.
    PubMed         Abstract available


    Neurobiol Dis

  53. PAPPOLLA MA, Perry G, Fang X, Zagorski M, et al
    Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease.
    Neurobiol Dis. 2021;156:105403.
    PubMed         Abstract available


    Neurology

  54. DONADIO V, Wang Z, Incensi A, Rizzo G, et al
    In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC.
    Neurology. 2021;96:e2513-e2524.
    PubMed         Abstract available

  55. HAZRATI LN, Schwab N
    Embracing the Unknown in the Diagnosis of Traumatic Encephalopathy Syndrome.
    Neurology. 2021;96:835-836.
    PubMed        

  56. FRIEDMAN LG, McKeehan N, Hara Y, Cummings JL, et al
    Value-Generating Exploratory Trials in Neurodegenerative Dementias.
    Neurology. 2021;96:944-954.
    PubMed         Abstract available


    Neurosci Lett

  57. RASHTIANI S, Goudarzi I, Jafari A, Rohampour K, et al
    Adenosine monophosphate activated protein kinase (AMPK) is essential for the memory improving effect of adiponectin.
    Neurosci Lett. 2021;749:135721.
    PubMed         Abstract available

  58. ANDROVICOVA R, Pfaus JG, Ovsepian SV
    Estrogen Pendulum in Schizophrenia and Alzheimer's Disease: Review of Therapeutic Benefits and Outstanding Questions.
    Neurosci Lett. 2021 Jun 8:136038. doi: 10.1016/j.neulet.2021.136038.
    PubMed         Abstract available


    PLoS Biol

  59. HAN F, Chen J, Belkin-Rosen A, Gu Y, et al
    Reduced coupling between cerebrospinal fluid flow and global brain activity is linked to Alzheimer disease-related pathology.
    PLoS Biol. 2021;19:e3001233.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  60. SADE YAZDI D, Laor Bar-Yosef D, Adsi H, Kreiser T, et al
    Homocysteine fibrillar assemblies display cross-talk with Alzheimer's disease beta-amyloid polypeptide.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed         Abstract available

  61. AHMED F
    QnAs with Robert Tycko.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed        


    Science

  62. SERVICK K
    Alzheimer's drug approved despite murky results.
    Science. 2021;372:1141.
    PubMed        


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