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  Alzheimer's Disease

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13.10.2025

1 Acta Neuropathol
14 Alzheimers Dement
1 Am J Geriatr Psychiatry
1 Biochemistry
3 Brain
1 Brain Res
1 Curr Alzheimer Res
3 Exp Neurol
5 J Alzheimers Dis
2 J Neurochem
2 Neurobiol Aging
1 Neurochem Res
1 Neurologia (Engl Ed)
1 Neurology
1 PLoS One


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. INOUE Y, Wang H, Heckman MG, Ren Y, et al
    Impact of APOE on cerebrovascular lipid profile in Alzheimer's disease.
    Acta Neuropathol. 2025;150:39.
    PubMed         Abstract available


    Alzheimers Dement

  2. CHEN S, Ou R, Wei Q, Li C, et al
    Lecanemab treatment for Alzheimer's Disease of varying severities and associated plasma biomarkers monitoring: A multi-center real-world study in China.
    Alzheimers Dement. 2025;21:e70750.
    PubMed         Abstract available

  3. BEDFORD LM, Tutrow KD, Hooper K, Messenger EJ, et al
    Alzheimer's disease-associated PLCG2 variants alter microglial state and function in human induced pluripotent stem cell-derived microglia-like cells.
    Alzheimers Dement. 2025;21:e70772.
    PubMed         Abstract available

  4. KWAPONG WR, Wu N, Lin W, Shen J, et al
    Retinal microvascular alterations in Alzheimer's disease: Linking blood plasma biomarkers and cerebral small vessel pathology.
    Alzheimers Dement. 2025;21:e70745.
    PubMed         Abstract available

  5. DEMPSEY DA, Agarwal P, Fernandez S, Brosch JR, et al
    Validation of a MIND diet screener in older adults.
    Alzheimers Dement. 2025;21:e70766.
    PubMed         Abstract available

  6. BOLTON CJ, Khan OA, Liu D, Pechman KR, et al
    Combining plasma p-tau(231) and glial fibrillary acidic protein produces higher discriminative accuracy for amyloid positivity than other blood-based biomarker combinations.
    Alzheimers Dement. 2025;21:e70796.
    PubMed         Abstract available

  7. OSEI GN, Bockarie A, Akpalu A, Adueming PO, et al
    Diagnostic potential of near-infrared spectroscopy in mild cognitive impairment and neurodegenerative disorders: Implications for resource-limited settings.
    Alzheimers Dement. 2025;21:e70769.
    PubMed         Abstract available

  8. LOGUE MW, Labadorf A, O'Neill NK, Dickson DW, et al
    Novel differentially expressed genes and multiple biological pathways for Alzheimer's disease identified in brain tissue from African American donors.
    Alzheimers Dement. 2025;21:e70629.
    PubMed         Abstract available

  9. ZEIGHAMI Y, Tremblay C, Dadar M
    Sex differences in vulnerability to tau pathology: Impact on cognitive decline.
    Alzheimers Dement. 2025;21:e70634.
    PubMed         Abstract available

  10. PEDERSEN TJ, Lu R, Toedebusch C, Hess A, et al
    Variability of longitudinal sleep monitoring in amyloid-negative and amyloid-positive cognitively unimpaired and mildly impaired older adults.
    Alzheimers Dement. 2025;21:e70761.
    PubMed         Abstract available

  11. PASCUAL-LUCAS M, Lacosta AM, Montanes M, Canudas J, et al
    Safety, tolerability, immunogenicity, and efficacy of ABvac40 active immunotherapy against Abeta40 in patients with mild cognitive impairment or very mild Alzheimer's disease: A randomized, double-blind, placebo-controlled phase 2 study.
    Alzheimers Dement. 2025;21:e70776.
    PubMed         Abstract available

  12. FULL KM, Liu D, Ibarra-Scurr DC, Wilkins CH, et al
    Development of a web platform to advance data-driven recruitment for ADRD research.
    Alzheimers Dement. 2025;21:e70722.
    PubMed         Abstract available

  13. CHU C, Ma L, Wang Y, Huynh ALH, et al
    Predicting severity of cerebral amyloid angiopathy neuropathology: A modeling approach using NACC and ROSMAP data.
    Alzheimers Dement. 2025;21:e70057.
    PubMed         Abstract available

  14. ERICHSEN JM, Register TC, Sutphen C, Ma D, et al
    A phase 2A/B randomized trial of metabolic modulators intranasal insulin and empagliflozin for MCI and early AD.
    Alzheimers Dement. 2025;21:e70704.
    PubMed         Abstract available

  15. WIJESINGHE P, Hosseini A, Campbell M, Tejpal S, et al
    Decoding amyloid beta clearance systems at inner blood-retina barrier using three-dimensional ex vivo retinal imaging in Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70592.
    PubMed         Abstract available


    Am J Geriatr Psychiatry

  16. CHERUBINI V, Prata O, Fattobene L, Ceravolo MG, et al
    Profiles of Vulnerability to Financial Exploitation in the Degenerative Dementias.
    Am J Geriatr Psychiatry. 2025;33:1290-1300.
    PubMed         Abstract available


    Biochemistry

  17. YOKOI T, Hayashi K, Morihara T, Murai T, et al
    Structural Characteristics of Docosahexaenoic Acid and Eicosapentaenoic Acid Inhibiting Amyloid-beta Fibrillation.
    Biochemistry. 2025;64:4242-4253.
    PubMed         Abstract available


    Brain

  18. RUIZ-REIG N, Virosztek M, Chehade G, Suelves N, et al
    KIF2A downregulation links amyloid-beta to Tau phosphorylation in Alzheimer's disease.
    Brain. 2025 Oct 10:awaf382. doi: 10.1093.
    PubMed         Abstract available

  19. ALEXANDERSEN CG, Bassett DS, Goriely A, Chaggar P, et al
    Neuronal activity and amyloid-beta promote tau seeding in the entorhinal cortex in Alzheimer's disease.
    Brain. 2025 Oct 7:awaf374. doi: 10.1093.
    PubMed         Abstract available

  20. KARLSSON L, Janelidze S, Barthelemy NR, Horie K, et al
    Reference proteins to improve Core 1 and Core 2 Alzheimer's disease CSF and plasma biomarkers.
    Brain. 2025 Oct 6:awaf375. doi: 10.1093.
    PubMed         Abstract available


    Brain Res

  21. ISMAIL A, Al-Kuraishy HM, Al-Gareeb AI, Albuhadily AK, et al
    Astrocyte response in Alzheimer's disease: Good or bad?
    Brain Res. 2025 Oct 6:149971. doi: 10.1016/j.brainres.2025.149971.
    PubMed         Abstract available


    Curr Alzheimer Res

  22. WANG R, Yang X
    Research Progress on the Pathogenesis, Therapeutic Strategies, and Phthalocyanine Compounds for Alzheimer's Disease.
    Curr Alzheimer Res. 2025 Oct 2. doi: 10.2174/0115672050406141250822082635.
    PubMed         Abstract available


    Exp Neurol

  23. LI S, Zheng F, Liu S, Wu R, et al
    Physical exercise protects neurons from energy deficit and improves cognitive function by upregulating astrocytic Slc2a1 in Alzheimer's disease.
    Exp Neurol. 2025 Oct 6:115493. doi: 10.1016/j.expneurol.2025.115493.
    PubMed         Abstract available

  24. ZHANG M, Hai S, Gao X, Cui Z, et al
    MYT1L promotes autophagy to ameliorate amyloid-beta pathology and cognitive deficits in Alzheimer's disease via Notch signaling pathway.
    Exp Neurol. 2025 Oct 6:115492. doi: 10.1016/j.expneurol.2025.115492.
    PubMed         Abstract available

  25. GENG D, Yan Y, Liu A, Zheng W, et al
    Experimental and computational study of 40?Hz low-field magnetic stimulation modulating neural activity and pathology in a mouse model of Alzheimer's disease.
    Exp Neurol. 2025 Oct 6:115494. doi: 10.1016/j.expneurol.2025.115494.
    PubMed         Abstract available


    J Alzheimers Dis

  26. TEIPEL S, Singh D, Dubbelman MA, Pan G, et al
    Early detection of Alzheimer's disease: From multiplex assays and imaging to point of care devices and AI-based functional monitoring.
    J Alzheimers Dis. 2025 Oct 7:13872877251383339. doi: 10.1177/13872877251383339.
    PubMed         Abstract available

  27. WEISS S, Harris K, Carney OL, Maza VI, et al
    Initial development of the writing to heal app: A structured writing series for caregivers of spouses living with Alzheimer's disease and related dementias.
    J Alzheimers Dis. 2025 Oct 9:13872877251378478. doi: 10.1177/13872877251378478.
    PubMed         Abstract available

  28. HANSON M, Liu Y, Ozawa T, Yin H, et al
    Potential barriers to timely Alzheimer's disease diagnosis and treatment: Tracer delivery and patient travel to amyloid PET scanners in the United States.
    J Alzheimers Dis. 2025 Oct 9:13872877251385118. doi: 10.1177/13872877251385118.
    PubMed         Abstract available

  29. KENNEMER AA, Gao Z, Davis PB, Kaelber DC, et al
    Timing of neurorehabilitation and subsequent Alzheimer's disease risk in patients with moderate to severe traumatic brain injury: A nationwide retrospective cohort study in the United States.
    J Alzheimers Dis. 2025 Oct 9:13872877251385262. doi: 10.1177/13872877251385262.
    PubMed         Abstract available

  30. ZHAO M, Yang J, Cheng H, Fan Y, et al
    Altered brain morphometry and its association with cognitive decline and APOE gene in normal people at risk for Alzheimer's disease.
    J Alzheimers Dis. 2025 Oct 10:13872877251384967. doi: 10.1177/13872877251384967.
    PubMed         Abstract available


    J Neurochem

  31. SANCHEZ DE MUNIAIN L, Escalada P, Ramirez MJ, Solas M, et al
    Astrocytes as Metabolic Sensors Orchestrating Energy-Driven Brain Vulnerability in Alzheimer's Disease.
    J Neurochem. 2025;169:e70252.
    PubMed         Abstract available

  32. CHU X, Guo Y, Fu Y, Ren H, et al
    An Amino Acid and Carnitine Metabolite Profile for the Early Detection and Differential Diagnosis of Alzheimer's Disease.
    J Neurochem. 2025;169:e70234.
    PubMed         Abstract available


    Neurobiol Aging

  33. MASHKANI SMH, Bishop D, Adlard PA, Mojtaba Golzan S, et al
    Zinc transporter proteins in the retina as potential biomarkers for staging early Alzheimer's disease: Comparative analysis in human and mouse models.
    Neurobiol Aging. 2025;157:26-35.
    PubMed         Abstract available

  34. KUZU TD, Brinkmann E, Bonkhoff AK, Wunderle V, et al
    Apraxic deficits in Alzheimer's disease are associated with altered dynamic connectivity in praxis-related networks.
    Neurobiol Aging. 2025;157:36-47.
    PubMed         Abstract available


    Neurochem Res

  35. YANG T
    Molecular Mechanisms of EDC-Induced Alzheimer's Disease and of Traditional Chinese Medicine Active Substances in Treating AD and Antagonizing EDC-Induced Effects.
    Neurochem Res. 2025;50:319.
    PubMed         Abstract available


    Neurologia (Engl Ed)

  36. JULIO-RAMOS T, Mora-Castelleto V, Foncea-Gonzalez C, Adames-Valencia C, et al
    Neuropsychological differential diagnosis of Alzheimer's Disease and Lewy Body Dementia: A systematic review.
    Neurologia (Engl Ed). 2025 Oct 6:S2173-5808(25)00096.
    PubMed         Abstract available


    Neurology

  37. EDWARDS NC, Lao P, Alshikho MJ, Mazen J, et al
    Alzheimer Disease, Vascular Disease, and Blood-Brain Barrier Permeability Biomarkers in Middle-Aged Adults.
    Neurology. 2025;105:e214220.
    PubMed         Abstract available


    PLoS One

  38. NOVOBILSKY R, Kusnierova P, Stepan D, Bartova P, et al
    Identification and evaluation of potential microRNA markers for diagnostics in neurodegenerative diseases and correlation with other biochemical markers.
    PLoS One. 2025;20:e0333801.
    PubMed         Abstract available


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