Decline in antibody responses to SARS-CoV-2 post-vaccination poses a risk to health care workers

Catherine M Worsley; Mieke A van der Mescht; Daniel Hoffmann; Pieter W A Meyer; Veronica Ueckermann; Theresa M Rossouw

doi:10.1016/j.jinf.2022.06.008

Decline in antibody responses to SARS-CoV-2 post-vaccination poses a risk to health care workers

J Infect. 2022 Sep;85(3):334-363. doi: 10.1016/j.jinf.2022.06.008. Epub 2022 Jun 12.

Authors

Catherine M Worsley¹, Mieke A van der Mescht², Daniel Hoffmann³, Pieter W A Meyer⁴, Veronica Ueckermann⁵, Theresa M Rossouw²

Affiliations

¹ Department of Immunology, Faculty of Health Science, University of Pretoria, South Africa; National Health Laboratory Service, South Africa. Electronic address: u05116602@up.ac.za.
² Department of Immunology, Faculty of Health Science, University of Pretoria, South Africa.
³ National Health Laboratory Service, South Africa; Department of Chemical Pathology, Faculty of Health Science, University of Pretoria, South Africa.
⁴ Department of Immunology, Faculty of Health Science, University of Pretoria, South Africa; National Health Laboratory Service, South Africa.
⁵ Department of Internal Medicine, Faculty of Health Science, University of Pretoria, South Africa.

No abstract available

Keywords: Abbreviations: HCW, health care worker; IGG, immunoglobulin g; IGM, immunoglobulin m; IQR, interquartile range; LFIA, lateral flow immunoassay; POC, point-of-care; SA-MRC, South African Medical Research Council; SAHPRA, South African Health Products Authority; VOC, variant of concern.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antibody Formation
COVID-19* / prevention & control
Health Personnel
Humans
SARS-CoV-2*
Vaccination / adverse effects