Case of Microcephaly after Congenital Infection with Asian Lineage Zika Virus, Thailand

Emerg Infect Dis. 2018 Sep;24(9):1758-1761. doi: 10.3201/eid2409.180416. Epub 2018 Sep 17.

Abstract

We sequenced the virus genomes from 3 pregnant women in Thailand with Zika virus diagnoses. All had infections with the Asian lineage. The woman infected at gestational week 9, and not those infected at weeks 20 and 24, had a fetus with microcephaly. Asian lineage Zika viruses can cause microcephaly.

Keywords: Asian lineage; Thailand; Zika virus; birth defects; congenital Zika virus infection with microcephaly; congenital infection; genome sequence; microcephaly; pregnancy; vector-borne infections; viruses.

Publication types

  • Case Reports
  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Humans
  • Infant, Newborn
  • Microcephaly / diagnosis*
  • Microcephaly / etiology
  • Pregnancy
  • Pregnancy Complications, Infectious*
  • Pregnancy Trimester, First
  • Thailand
  • Zika Virus / genetics
  • Zika Virus / isolation & purification*
  • Zika Virus Infection*