Alternate paradigms on Zika virus-related complications: An analytical review

Asian Pac J Trop Med. 2017 Jul;10(7):631-634. doi: 10.1016/j.apjtm.2017.07.003. Epub 2017 Jul 28.

Abstract

The proportion of the reported cases of Zika virus (ZIKV) infection reached the status of a pandemic. Numerous studies are being conducted on the isolation of ZIKV strains from various epidemics, diagnosis of the infections, various animal models and cell culture designs to study the pathogenesis of ZIKV in the attempts to find an effective ZIKV vaccine. This review focuses upon the 'Off-Spectrum' body of studies which analyses the epidemiology, pathogenesis and other attributes of ZIKV in the light of various dissident hypotheses.

Keywords: Koch's postulates; Microcephaly; Neurotropism; Placenta; Vaccines; Zika virus.

Publication types

  • Review