A Single Substitution Changes Zika Virus Infectivity in Mosquitoes

Guan-Zhu Han

doi:10.1016/j.tim.2017.05.014

A Single Substitution Changes Zika Virus Infectivity in Mosquitoes

Trends Microbiol. 2017 Aug;25(8):603-605. doi: 10.1016/j.tim.2017.05.014. Epub 2017 Jun 10.

Author

Guan-Zhu Han¹

Affiliation

¹ Jiangsu Key Laboratory for Microbes and Functional Genomics, Jiangsu Engineering and Technology Research Center for Microbiology, College of Life Sciences, Nanjing Normal University, Nanjing, Jiangsu 210046, China . Electronic address: guanzhu@njnu.edu.cn.

PMID: 28610876
DOI: 10.1016/j.tim.2017.05.014

Abstract

Zika virus (ZIKV) has caused outbreaks in the Pacific and the Americas. The mechanism underlying the recent ZIKV epidemic remains obscure. A recent study reveals that an amino acid substitution is associated with increased infectivity of ZIKV in the Aedes aegypti mosquito.

Keywords: Zika virus; amino acid substitution; transmission vector.

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MeSH terms

Aedes*
Americas
Animals
Mosquito Vectors
Saliva
Zika Virus*