Microcephaly Case Fatality Rate Associated with Zika Virus Infection in Brazil: Current Estimates

Pediatr Infect Dis J. 2017 May;36(5):528-530. doi: 10.1097/INF.0000000000001486.

Abstract

Considering the currently confirmed cases of microcephaly and related deaths associated with Zika virus in Brazil, the estimated case fatality rate is 8.3% (95% confidence interval: 7.2-9.6). However, a third of the reported cases remain under investigation. If the confirmation rates of cases and deaths are the same in the future, the estimated case fatality rate will be as high as 10.5% (95% confidence interval: 9.5-11.7).

MeSH terms

  • Adult
  • Brazil / epidemiology
  • Disease Outbreaks*
  • Female
  • Fetus
  • Humans
  • Infant
  • Infant, Newborn
  • Microcephaly / epidemiology*
  • Microcephaly / etiology
  • Microcephaly / mortality
  • Microcephaly / virology
  • Perinatal Mortality / trends*
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / mortality
  • Pregnancy Complications, Infectious / virology
  • Survival Analysis
  • Zika Virus / pathogenicity
  • Zika Virus / physiology
  • Zika Virus Infection / complications
  • Zika Virus Infection / epidemiology*
  • Zika Virus Infection / mortality
  • Zika Virus Infection / virology