[Ocular manifestations of Zika virus: What we do and do not know]

J Fr Ophtalmol. 2017 Feb;40(2):138-145. doi: 10.1016/j.jfo.2017.01.002. Epub 2017 Feb 9.
[Article in French]

Abstract

Zika virus (ZIKV) disease outbreak, which was declared by the end of 2015 in Brazil, has become the largest one to date. Being reported in the Americas and in certain islands of the Pacific, it has the potential to spread worldwide. Although ZIKV infections are mostly self-limiting and/or asymptomatic in the healthy adult, they are responsible for devastating congenital neurologic malformations ZIKV (mainly microcephaly) when contracted during the first months of pregnancy. Ocular manifestations during the acute adult infection include conjunctivitis and more rarely ocular inflammation. Congenital infection is associated with chorioretinal atrophy pigment mottling of the retina retinal vasculature abnormalities and optic nerve atrophy. Therefore, complete ophthalmological evaluation is recommended for suspected congenital infections.

Keywords: Conjonctivite; Conjunctivitis; Epidemics; Maculopathie; Maculopathy; Microcephaly; Microcéphalie; Uveitis; Uvéite; Virus; Zika; Épidémie.

Publication types

  • Review

MeSH terms

  • Brazil / epidemiology
  • Disease Outbreaks
  • Epidemics
  • Eye Infections, Viral / congenital
  • Eye Infections, Viral / diagnosis*
  • Eye Infections, Viral / epidemiology
  • Eye Infections, Viral / therapy*
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / diagnosis
  • Infant, Newborn, Diseases / epidemiology
  • Infant, Newborn, Diseases / therapy
  • Infectious Disease Transmission, Vertical / statistics & numerical data
  • Neonatal Screening / methods
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / therapy
  • Zika Virus Infection / congenital
  • Zika Virus Infection / diagnosis*
  • Zika Virus Infection / epidemiology
  • Zika Virus Infection / therapy*