Zika and pregnancy: A comprehensive review

Am J Reprod Immunol. 2017 Feb;77(2). doi: 10.1111/aji.12607. Epub 2016 Nov 25.

Abstract

Zika virus (ZIKV) infection is a well-nurtured topic for healthcare personnel nowadays. Central nervous system involvement including microcephaly and ocular involvements has already been reported in neonates of affected pregnant ladies. In this article, we have discussed these effects on the newborns of ZIKV-infected mothers. The proposed pathogenesis, modes of transmission of this infection from mothers to the fetuses, diagnosis of the cases and precaution for the pregnant ladies have also been discussed. We have gathered the recently available data on the risk of ZIKV for expectant mothers from PubMed, https://www.gov.uk/guidance/zika-virus as well as from centers for disease control and prevention websites.

Keywords: Zika virus infection; fetal anomaly; microcephaly; pregnancy.

Publication types

  • Review

MeSH terms

  • Animals
  • Centers for Disease Control and Prevention, U.S.
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / epidemiology*
  • Infectious Disease Transmission, Vertical
  • Microcephaly / epidemiology*
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • PubMed
  • Risk
  • United States
  • Zika Virus / physiology*
  • Zika Virus Infection / epidemiology*