Zika virus infection and biological treatment for reproductive medicine

Am J Reprod Immunol. 2017 Feb;77(2). doi: 10.1111/aji.12606. Epub 2016 Nov 21.

Abstract

The recent Zika virus (ZIKV) epidemic is particularly challenging in the field of reproductive medicine as various biological tissues and byproducts, such as intravenous immunoglobulin G or cells are utilized during reproductive cycles, and an infected mother has an increased risk of having babies with fetal microcephaly and other congenital brain anomalies. In this review, current guidelines for prevention of sexual transmission of ZIKV, ZIKV testing, and tissue and blood product usages are summarized for physicians caring for those planning pregnancy or going through infertility treatment.

Keywords: IVIG; Zika; guidelines; immunotherapy; infertility; pregnancy.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Therapy*
  • Female
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Infant, Newborn
  • Infant, Newborn, Diseases / epidemiology*
  • Infectious Disease Transmission, Vertical*
  • Mass Screening
  • Microcephaly / epidemiology*
  • Practice Guidelines as Topic
  • Pregnancy
  • Reproductive Medicine*
  • Zika Virus / physiology*
  • Zika Virus Infection / epidemiology
  • Zika Virus Infection / therapy*

Substances

  • Immunoglobulins, Intravenous