First Travel-Associated Congenital Zika Syndrome in the US: Ocular and Neurological Findings in the Absence of Microcephaly

Ophthalmic Surg Lasers Imaging Retina. 2016 Oct 1;47(10):952-955. doi: 10.3928/23258160-20161004-09.

Abstract

A 6-day-old female baby with known diagnosis of congenital Zika infection was referred for ophthalmologic examination. The mother (37 years old) was referred for a pruritic rash, conjunctival hyperemia, and malaise at 12 weeks of gestation while still living in Venezuela. Upon arrival to Miami, Zika virus (ZIKV) exposure was confirmed during prenatal screening. At birth, due to the known exposure, a complete congenital ZIKV workup was performed, including brain ultrasound and MRI, which disclosed calcifications in the frontal lobe. Fundus examination revealed a hypopigmented retinal lesion in the left eye that was documented with retinal imaging. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:952-955.].

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / diagnostic imaging*
  • Female
  • Florida / epidemiology
  • Humans
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Microcephaly
  • Optic Nerve / diagnostic imaging*
  • Syndrome
  • Travel*
  • Venezuela / ethnology
  • Zika Virus Infection / congenital*
  • Zika Virus Infection / diagnosis
  • Zika Virus Infection / ethnology
  • Zika Virus*