Zika Virus: Immunity and Vaccine Development

Cell. 2016 Oct 20;167(3):625-631. doi: 10.1016/j.cell.2016.09.020. Epub 2016 Sep 29.

Abstract

The emergence of Zika virus in the Americas and Caribbean created an urgent need for vaccines to reduce transmission and prevent disease, particularly the devastating neurodevelopmental defects that occur in utero. Rapid advances in Zika immunity and the development of vaccine candidates provide cautious optimism that preventive measures are possible.

Publication types

  • Research Support, N.I.H., Intramural
  • Review

MeSH terms

  • Antibodies, Viral / blood
  • Antibodies, Viral / immunology
  • Humans
  • Immunity, Innate
  • T-Lymphocytes / immunology
  • Viral Vaccines / immunology*
  • Zika Virus / immunology*
  • Zika Virus Infection / blood
  • Zika Virus Infection / immunology*
  • Zika Virus Infection / prevention & control*
  • Zika Virus Infection / transmission

Substances

  • Antibodies, Viral
  • Viral Vaccines