Complete Genome Sequences of Three Historically Important, Spatiotemporally Distinct, and Genetically Divergent Strains of Zika Virus: MR-766, P6-740, and PRVABC-59

Sang-Im Yun; Byung-Hak Song; Jordan C Frank; Justin G Julander; Irina A Polejaeva; Christopher J Davies; Kenneth L White; Young-Min Lee

doi:10.1128/genomeA.00800-16

Complete Genome Sequences of Three Historically Important, Spatiotemporally Distinct, and Genetically Divergent Strains of Zika Virus: MR-766, P6-740, and PRVABC-59

Genome Announc. 2016 Aug 18;4(4):e00800-16. doi: 10.1128/genomeA.00800-16.

Authors

Sang-Im Yun¹, Byung-Hak Song¹, Jordan C Frank¹, Justin G Julander¹, Irina A Polejaeva¹, Christopher J Davies¹, Kenneth L White¹, Young-Min Lee²

Affiliations

¹ Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, Utah, USA.
² Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, Utah, USA youngmin.lee@usu.edu.

Abstract

Here, we report the 10,807-nucleotide-long consensus RNA genome sequences of three spatiotemporally distinct and genetically divergent Zika virus strains, with the functionality of their genomic sequences substantiated by reverse genetics: MR-766 (African lineage, Uganda, 1947), P6-740 (Asian lineage, Malaysia, 1966), and PRVABC-59 (Asian lineage-derived American strain, Puerto Rico, 2015).

Grants and funding

This work was supported by grants from the Utah Science Technology and Research initiative (A34637 and A36815). Also, this research was approved as journal paper number UAES #8903. The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.