Placental Mechanics in the Zika-Microcephaly Relationship

Cell Host Microbe. 2016 Jul 13;20(1):9-11. doi: 10.1016/j.chom.2016.06.013.

Abstract

How the Zika virus (ZIKV) accesses the embryo remains unknown. In this issue, Quicke et al. (2016) use an in vitro model of the human placenta to show that placental macrophages are more permissive to ZIKV infection than trophoblasts, which may be refractory to infection (Bayer et al., 2016).

Publication types

  • Comment

MeSH terms

  • Animals
  • Female
  • Humans
  • Mammals
  • Microcephaly / virology*
  • Placenta
  • Pregnancy
  • Zika Virus
  • Zika Virus Infection*