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Tuberculosis

Free Subscription Articles published in Antimicrob Agents Chemother Retrieve available abstracts of 73 articles: HTML format Text format

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January 2012
1. WARRIER T , Tropis M, Werngren J, Diehl A, et al
   Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis.
   Antimicrob Agents Chemother. 2012.
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2. PANTEL A , Petrella S, Veziris N, Brossier F, et al
   Extending GyrB QRDR definition in Mycobacterium tuberculosis DNA gyrase for assessing FQ resistance in M. tuberculosis.
   Antimicrob Agents Chemother. 2012.
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3. TAHLAN K , Wilson R, Kastrinsky DB, Arora K, et al
   SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis.
   Antimicrob Agents Chemother. 2012.
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4. SMYTHE W , Khandelwal A, Merle C, Rustomjee R, et al
   A semi-mechanistic pharmacokinetic-enzyme turn-over model for rifampicin autoinduction in adult tuberculosis patients.
   Antimicrob Agents Chemother. 2012.
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   December 2011
5. WERNGREN J , Sturegard E, Jureen P, Angeby K, et al
   Re-evaluation of the critical concentration for drug susceptibility testing of Mycobacterium tuberculosis against pyrazinamide using wild-type MIC distributions and pncA gene sequencing.
   Antimicrob Agents Chemother. 2011.
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6. WIVAGG CN , Hung DT
   Resuscitation-Promoting Factors Are Required for beta-Lactam Tolerance and the Permeability Barrier in Mycobacterium tuberculosis.
   Antimicrob Agents Chemother. 2011.
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7. ROUAN MC , Lounis N, Gevers T, Dillen L, et al
   Pharmacokinetics-Pharmacodynamics of TMC207 and its N-desmethyl Metabolite in a Murine Model of Tuberculosis.
   Antimicrob Agents Chemother. 2011.
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8. ROY CJ , Sivasubramani SK, Dutta NK, Mehra S, et al
   Aerosolized Gentamicin Reduces the Burden of Tuberculosis in a Murine Model.
   Antimicrob Agents Chemother. 2011.
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9. DE GROOTE MA , Gruppo V, Woolhiser LK, Orme IM, et al
   Importance of Confirming in vivo Efficacy Data of Novel Antibacterial Drug Regimens against Various Strains of Mycobacterium tuberculosis.
   Antimicrob Agents Chemother. 2011.
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   November 2011
10. GRAU T , Selchow P, Tigges M, Burri R, et al
    Phenylethyl-butyrate enhances the potency of second-line drugs against clinical isolates of M. tuberculosis.
    Antimicrob Agents Chemother. 2011.
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    October 2011
11. KJELLSSON MC , Via LE, Goh A, Weiner D, et al
    Penetration of anti-tuberculosis agents in rabbit pulmonary lesions: a pharmacokinetic evaluation.
    Antimicrob Agents Chemother. 2011.
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12. HEYSELL SK , Mtabho C, Mpagama S, Mwaigwisya S, et al
    A plasma drug activity assay for treatment optimization in tuberculosis patients.
    Antimicrob Agents Chemother. 2011.
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13. THEE S , Seddon JA, Donald PR, Seifar HI, et al
    PHARMACOKINETICS OF ISONIAZID, RIFAMPICIN AND PYRAZINAMIDE IN CHILDREN YOUNGER THAN TWO YEARS OF AGE WITH TUBERCULOSIS; EVIDENCE FOR IMPLEMENTATION OF REVISED WORLD HEALTH ORGANIZATION RECOMMENDATIONS.
    Antimicrob Agents Chemother. 2011.
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    September 2011
14. TASNEEN R , Li SY, Peloquin CA, Taylor D, et al
    Sterilizing activity of novel TMC207- and PA-824-containing regimens in a murine model of tuberculosis.
    Antimicrob Agents Chemother. 2011.
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15. FEUERRIEGEL S , Koser CU, Bau D, Rusch-Gerdes S, et al
    Impact of fgd1 and ddn diversity in Mycobacterium tuberculosis complex on in vitro susceptibility to PA-824.
    Antimicrob Agents Chemother. 2011.
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16. ALI A , Hasan R, Jabeen K, Jabeen N, et al
    Characterization of mutations conferring extensive drug resistance to M. tuberculosis isolates in Pakistan.
    Antimicrob Agents Chemother. 2011.
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17. SRIVASTAVA S , Sherman C, Meek C, Leff R, et al
    Pharmacokinetic mismatch does not lead to emergence of isoniazid or rifampin-resistant Mycobacterium tuberculosis, but better antimicrobial effect: a new paradigm for anti-tuberculosis drug scheduling.
    Antimicrob Agents Chemother. 2011.
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18. ANGEBY K , Giske CG, Jureen P, Schon T, et al
    Wild-Type MIC Distributions Must Be Considered To Set Clinically Meaningful Susceptibility Testing Breakpoints for All Bacterial Pathogens, Including Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2011;55:4492-3.
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    August 2011
19. LU Y , Zheng M, Wang B, Fu L, et al
    Clofazimine Analogs with Efficacy against Experimental Tuberculosis and Reduced Potential for Accumulation.
    Antimicrob Agents Chemother. 2011.
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20. HEYSELL SK , Houpt ER
    Optimizing second-line therapy for drug-resistant tuberculosis: the additive value of sequencing for multiple resistance Loci.
    Antimicrob Agents Chemother. 2011;55:3968-9.
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    July 2011
21. CHANG KC , Yew WW, Zhang Y
    Pyrazinamide susceptibility testing in Mycobacterium tuberculosis: a systematic review with meta-analyses.
    Antimicrob Agents Chemother. 2011.
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22. PANTEL A , Petrella S, Matrat S, Brossier F, et al
    DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2011.
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    June 2011
23. PROJAHN M , Koser CU, Homolka S, Summers DK, et al
    Polymorphisms in isoniazid and prothionamide resistance genes of the Mycobacterium tuberculosis complex.
    Antimicrob Agents Chemother. 2011.
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24. JONSSON S , Davidse A, Wilkins J, Van der Walt JS, et al
    Population pharmacokinetics of ethambutol in South African tuberculosis patients.
    Antimicrob Agents Chemother. 2011.
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25. KAPOOR R , Eimerman PR, Hardy JW, Cirillo JD, et al
    Efficacy of antimicrobial peptoids against Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2011;55:3058-62.
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    May 2011
26. VILCHEZE C , Baughn AD, Tufariello J, Leung L, et al
    Novel inhibitors of InhA efficiently kill Mycobacterium tuberculosis under aerobic and anaerobic conditions.
    Antimicrob Agents Chemother. 2011.
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27. FOO DG , Tay HC, Siew JY, Singhal A, et al
    T cell monitoring of chemotherapy in experimental rat tuberculosis.
    Antimicrob Agents Chemother. 2011.
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28. RAMON-GARCIA S , Ng C, Anderson H, Chao JD, et al
    Synergistic drug combinations for tuberculosis therapy identified by a novel high throughput screen.
    Antimicrob Agents Chemother. 2011.
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29. SEKIGUCHI JI , Disratthakit A, Maeda S, Doi N, et al
    Characteristic Resistance Mechanism of DC-159a, a New Respiratory Quinolone, in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2011.
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    April 2011
30. THWAITES GE , Bhavnani SM, Thi Hong Chau T, Hammel JP, et al
    A randomised pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis.
    Antimicrob Agents Chemother. 2011.
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31. KOSER CU , Summers DK, Archer JA
    Thr270Ile in embC (Rv3793) Is Not a Marker for Ethambutol Resistance in the Mycobacterium tuberculosis Complex.
    Antimicrob Agents Chemother. 2011;55:1825.
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    March 2011
32. WONG SY , Lee JS, Kwak HK, Via LE, et al
    Mutations in gidB confer low-level streptomycin resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2011.
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33. PLINKE C , Walter K, Aly S, Ehlers S, et al
    Mycobacterium tuberculosis embB306 mutations confer moderately increased resistance to Ethambutol in vitro and in vivo.
    Antimicrob Agents Chemother. 2011.
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34. VEZIRIS N , Truffot C, Mainardi JL, Jarlier V, et al
    Activity of carbapenems combined with clavulanate in murine tuberculosis.
    Antimicrob Agents Chemother. 2011.
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    February 2011
35. CAMPBELL PJ , Morlock GP, Sikes RD, Dalton TL, et al
    Molecular Detection of Mutations Associated with First and Second-Line Drug Resistance Compared with Conventional Drug Susceptibility Testing in M. tuberculosis.
    Antimicrob Agents Chemother. 2011.
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    January 2011
36. AHMAD Z , Fraig MM, Bisson GP, Nuermberger EL, et al
    Dose-dependent activity of pyrazinamide in animal models of intracellular and extracellular tuberculosis.
    Antimicrob Agents Chemother. 2011.
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37. AHMAD Z , Minkowski A, Peloquin CA, Williams KN, et al
    Activity of the fluoroquinolone DC-159a in the initial and continuation phase treatment of murine tuberculosis.
    Antimicrob Agents Chemother. 2011.
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38. ALFFENAAR JW , van der Laan T, Simons S, van der Werf TS, et al
    Susceptibility of clinical Mycobacterium tuberculosis isolates to a potentially less toxic derivate of linezolid; PNU-100480.
    Antimicrob Agents Chemother. 2011.
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39. PASIPANODYA J , Gumbo T
    An oracle: antituberculosis pharmacokinetics-pharmacodynamics, clinical correlation, and clinical trial simulations to predict the future.
    Antimicrob Agents Chemother. 2011;55:24-34.
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    December 2010
40. RAFIQ Y , Jabeen K, Hasan R, Jafri S, et al
    Fluoroquinolone resistance amongst Mycobacterium tuberculosis strains from Karachi, Pakistan; Data from community based field clinics.
    Antimicrob Agents Chemother. 2010.
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41. DE GROOTE MA , Gilliland JC, Wells CL, Brooks EJ, et al
    Comparative studies evaluating mouse models used for efficacy testing of experimental drugs against M. tuberculosis.
    Antimicrob Agents Chemother. 2010.
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42. MITCHISON DA
    Activity of pyrazinamide in the Guinea pig model of tuberculosis.
    Antimicrob Agents Chemother. 2010;54:5420.
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43. BOLHUIS MS , van Altena R, Uges DR, van der Werf TS, et al
    Clarithromycin significantly increases linezolid serum concentrations.
    Antimicrob Agents Chemother. 2010;54:5418-9.
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    November 2010
44. JEENA PM , Bishai WR, Pasipanodya JG, Gumbo T, et al
    In silico Children and the Glass Mouse: Clinical Trial Simulations to Identify and Individualize Optimal Isoniazid Doses in Children With Tuberculosis.
    Antimicrob Agents Chemother. 2010.
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45. WALLIS RS , Jakubiec W, Kumar V, Bedarida G, et al
    Biomarker-assisted dose selection for safety and efficacy in early development of PNU-100480 for tuberculosis.
    Antimicrob Agents Chemother. 2010.
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46. KOSER CU , Summers DK, Archer JA
    Role of the dihydrofolate reductase DfrA (Rv2763c) in trimethoprim-sulfamethoxazole (co-trimoxazole) resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2010;54:4951-2.
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47. POISSY J , Aubry A, Fernandez C, Lott MC, et al
    Should moxifloxacin be used for the treatment of extensively drug-resistant tuberculosis? An answer from a murine model.
    Antimicrob Agents Chemother. 2010;54:4765-71.
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    October 2010
48. BROSSIER F , Veziris N, Truffot-Pernot C, Jarlier V, et al
    Molecular Investigation of Resistance to the Antituberculous Drug Ethionamide in Multidrug-Resistant Clinical Isolates of Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2010.
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49. LAU RW , Ho PL, Kao RY, Yew WW, et al
    Molecular Characterization of Fluoroquinolone Resistance in Mycobacterium tuberculosis: Functional Analysis of gyrA Mutant at Position 74.
    Antimicrob Agents Chemother. 2010.
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50. BRUNING JB , Murillo AC, Chacon O, Barletta RG, et al
    Structure of the Mycobacterium tuberculosis D-alanine:D-alanine Ligase: a target of the anti-tuberculosis drug D-cycloserine.
    Antimicrob Agents Chemother. 2010.
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51. SHANG S , Shanley CA, Caraway ML, Orme EA, et al
    The activity of TMC 207, rifampin, and pyrazinamide against Mycobacterium tuberculosis infection in guinea pigs.
    Antimicrob Agents Chemother. 2010.
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52. AHMAD Z , Peloquin CA, Singh RP, Derendorf H, et al
    PA-824 exhibits time-dependent activity in a murine model of tuberculosis.
    Antimicrob Agents Chemother. 2010.
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53. BALGANESH M , Kuruppath S, Marcel N, Sharma S, et al
    Rv1218c, an ABC transporter of Mycobacterium tuberculosis with implications in drug discovery.
    Antimicrob Agents Chemother. 2010.
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54. KOSER CU , Veerapen-Pierce RN, Summers DK, Archer JA, et al
    Role of mutations in dihydrofolate reductase DfrA (Rv2763c) and thymidylate synthase ThyA (Rv2764c) in Mycobacterium tuberculosis drug resistance.
    Antimicrob Agents Chemother. 2010;54:4522-3.
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    September 2010
55. GARCIA AB , Palacios JJ, Ruiz MJ, Barluenga J, et al
    Strong In Vitro Activity of Two New Rifabutin Analogs against Multidrug-resistant Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2010.
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    August 2010
56. FEUERRIEGEL S , Koser C, Trube L, Archer J, et al
    Thr202Ala in thyA is a marker for the Latin American Mediterranean lineage of the Mycobacterium tuberculosis complex rather than para-aminosalicylic acid resistance.
    Antimicrob Agents Chemother. 2010.
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57. KHANNA A , Raj VS, Tarai B, Sood R, et al
    Emergence of Extensive Drug Resistant (XDR) Mycobacterium tuberculosis and Molecular Characterization of these clinical isolates from Delhi Region, India.
    Antimicrob Agents Chemother. 2010.
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58. ANDRIES K , Gevers T, Lounis N
    Bactericidal Potencies of New Regimens are not Predictive for their Sterilizing Potencies in a Murine Model of Tuberculosis.
    Antimicrob Agents Chemother. 2010.
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59. SALA C , Dhar N, Hartkoorn RC, Zhang M, et al
    A Simple Model for Testing Drugs against Non-replicating Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2010.
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    July 2010
60. WEINER M , Peloquin C, Burman W, Luo CC, et al
    The effects of tuberculosis, race and human gene SLCO1B1 polymorphisms on rifampin concentrations.
    Antimicrob Agents Chemother. 2010.
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    June 2010
61. WANG F , Jain P, Gulten G, Liu Z, et al
    Mycobacterium tuberculosis Dihydrofolate Reductase is Not a Target Relevant to the Anti-tubercular Activity of Isoniazid.
    Antimicrob Agents Chemother. 2010.
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62. ONG W , Sievers A, Leslie DE
    Mycobacterium tuberculosis and sulfamethoxazole susceptibility.
    Antimicrob Agents Chemother. 2010;54:2748.
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63. PUCCI MJ , Ackerman M, Thanassi JA, Shoen CM, et al
    In Vitro Antituberculosis Activities of ACH-702, a Novel Isothiazoloquinolone, against Quinolone-Susceptible and Quinolone-Resistant Isolates.
    Antimicrob Agents Chemother. 2010.
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    May 2010
64. DIACON AH , Dawson R, Hanekom M, Narunsky K, et al
    Early Bactericidal Activity and Pharmacokinetics of PA-824 in Smear-Positive Tuberculosis Patients.
    Antimicrob Agents Chemother. 2010.
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    April 2010
65. GUMBO T
    New susceptibility breakpoints for first-line antituberculosis drugs based on antimicrobial pharmacokinetic/pharmacodynamic science and population pharmacokinetic variability.
    Antimicrob Agents Chemother. 2010;54:1484-91.
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    March 2010
66. FILIPPINI P , Iona E, Piccaro G, Peyron P, et al
    Activity of drug combinations against dormant Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2010.
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67. MOLINA-TORRES CA , Ocampo-Candiani J, Rendon A, Pucci MJ, et al
    In vitro activity of a new Isothiazoloquinolone (ACH-702) against Mycobacterium tuberculosis and other mycobacteria.
    Antimicrob Agents Chemother. 2010.
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68. ANDO H , Kondo Y, Suetake T, Toyota E, et al
    Identification of katG mutations associated with high-level isoniazid resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2010.
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69. LUO T , Zhao M, Li X, Xu P, et al
    Selection of mutations to detect multidrug-resistant Mycobacterium tuberculosis strains in Shanghai, China.
    Antimicrob Agents Chemother. 2010;54:1075-81.
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    February 2010
70. ORDWAY DJ , Shanley CA, Caraway ML, Orme EA, et al
    Evaluation of standard chemotherapy in the guinea pig model of tuberculosis.
    Antimicrob Agents Chemother. 2010.
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71. RULLAS J , Garcia JI, Beltran M, Cardona PJ, et al
    A fast standardized therapeutic efficacy assay for drug discovery in tuberculosis.
    Antimicrob Agents Chemother. 2010.
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    January 2010
72. GARCIA-CONTRERAS L , Sung JC, Muttil P, Padilla D, et al
    Dry Powder PA-824 Aerosols for the Treatment of Tuberculosis in Guinea Pigs.
    Antimicrob Agents Chemother. 2010.
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73. PASCA MR , Degiacomi G, Ribeiro AL, Zara F, et al
    Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones.
    Antimicrob Agents Chemother. 2010.
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