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	Amedeo Prize 2008 The 21 Finalists

Tuberculosis

Free Subscription Articles published in Antimicrob Agents Chemother Retrieve available abstracts of 54 articles: HTML format

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April 2008
1. MATRAT S , Aubry A, Mayer C, Jarlier V, et al
   Mutagenesis in the {alpha}3{alpha}4 GyrA Helix and in the Toprim domain of GyrB Refines the Contribution of Mycobacterium tuberculosis DNA Gyrase to Intrinsic Resistance to Quinolones.
   Antimicrob Agents Chemother. 2008;.
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2. HUANG TS , Liu YC, Sy CL, Chen YS, et al
   In Vitro Activities of Linezolid against Clinical Isolates of Mycobacterium tuberculosis complex Isolated in Taiwan over Ten Years.
   Antimicrob Agents Chemother. 2008;.
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3. WILKINS JJ , Savic RM, Karlsson MO, Langdon G, et al
   Population pharmacokinetics of rifampin in pulmonary tuberculosis patients including a semi-mechanistic model to describe variable absorption.
   Antimicrob Agents Chemother. 2008;.
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   March 2008
4. SAFI H , Sayers B, Hazbon MH, Alland D, et al
   Transfer of embB306 mutations into clinical Mycobacterium tuberculosis alters susceptibility to ethambutol, isoniazid and rifampin.
   Antimicrob Agents Chemother. 2008;.
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5. JUREEN P , Werngren J, Toro JC, Hoffner S, et al
   Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis.
   Antimicrob Agents Chemother. 2008;.
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   February 2008
6. NUERMBERGER E , Tyagi S, Tasneen R, Williams KN, et al
   Powerful bactericidal and sterilizing activity of a regimen containing PA-824, moxifloxacin and pyrazinamide in the murine model of tuberculosis.
   Antimicrob Agents Chemother. 2008;.
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7. LENAERTS AJ , Bitting C, Woolhiser L, Gruppo V, et al
   Evaluation of a 2-pyridone, KRQ-10018, against Mycobacterium tuberculosis in vitro and in vivo.
   Antimicrob Agents Chemother. 2008;.
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   December 2007
8. PELOQUIN CA , Hadad DJ, Molino LP, Palaci M, et al
   Population Pharmacokinetics of Levofloxacin, Gatifloxacin, and Moxifloxacin in Adults with Pulmonary Tuberculosis.
   Antimicrob Agents Chemother. 2007;.
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9. HILLEMANN D , Rusch-Gerdes S, Richter E
   In Vitro selected Linezolid-Resistant Mycobacterium tuberculosis Mutants.
   Antimicrob Agents Chemother. 2007;.
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10. GEGIA M , Mdivani N, Mendes RE, Li H, et al
    Prevalence of and Molecular Basis for Tuberculosis Drug Resistance in the Republic of Georgia: Validation of a QIAplex System for the Detection of Drug Resistance-Related Mutations.
    Antimicrob Agents Chemother. 2007;.
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    October 2007
11. ALMEIDA D , Nuermberger E, Tyagi S, Bishai WR, et al
    In vivo Validation of the Mutant Selection Window Hypothesis with Moxifloxacin in a Murine Model of Tuberculosis.
    Antimicrob Agents Chemother. 2007;.
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    September 2007
12. BYRNE ST , Gu P, Zhou J, Denkin SM, et al
    Pyrrolidine dithiocarbamate (PDTC) and diethyldithiocarbamate (DETC) are active against growing and non-growing persister Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2007;.
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13. BRIMACOMBE M , Hazbon M, Motiwala AS, Alland D, et al
    Antibiotic Resistance and SNP Cluster Grouping Type In a Multi-national Sample of M. tuberculosis Resistant Isolates.
    Antimicrob Agents Chemother. 2007;.
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14. SHI R , Zhang J, Otomo K, Zhang G, et al
    Lack of Correlation Between embB Mutation and Ethambutol Minimal Inhibitory Concentration in Mycobacterium tuberculosis Clinical Isolates from China.
    Antimicrob Agents Chemother. 2007;.
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15. KORDULAKOVA J , Janin YL, Liav A, Barilone N, et al
    Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2007;.
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    August 2007
16. GUMBO T , Louie A, Deziel MR, Liu W, et al
    Concentration-dependent Mycobacterium tuberculosis killing and prevention of resistance by rifampin.
    Antimicrob Agents Chemother. 2007;.
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    July 2007
17. YADAV AB , Misra A
    Enhancement of Apoptosis of THP-1 Cells Infected with Mycobacterium tuberculosis by Inhalable Microparticles and Relevance to Bactercidal Activity.
    Antimicrob Agents Chemother. 2007;.
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18. BOYNE ME , Sullivan TJ, Am Ende CW, Lu H, et al
    Targeting fatty acid biosynthesis for the development of novel chemotherapeutics against Mycobacterium tuberculosis: Evaluation of A-ring modified diphenyl ethers as high affinity InhA inhibitors.
    Antimicrob Agents Chemother. 2007;.
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    June 2007
19. ACOSTA EP , Kendall MA, Gerber JG, Alston-Smith B, et al
    Effect of Concomitant Rifampin on the Pharmacokinetics and Safety of Twice-Daily Atazanavir: ACTG Protocol A5213.
    Antimicrob Agents Chemother. 2007;.
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    May 2007
20. DIACON AH , Patientia RF, Venter A, van Helden PD, et al
    THE EARLY BACTERICIDAL ACTIVITY OF HIGH DOSE RIFAMPIN IN PATIENTS WITH SPUTUM SMEAR-POSITIVE PULMONARY TUBERCULOSIS.
    Antimicrob Agents Chemother. 2007;.
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21. GARCIA-CONTRERAS L , Fiegel J, Telko MJ, Elbert K, et al
    INHALED CAPREOMYCIN LARGE POROUS PARTICLES FOR THE TREATMENT OF TUBERCULOSIS IN THE GUINEA PIG MODEL.
    Antimicrob Agents Chemother. 2007;.
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22. LENAERTS AJ , Hoff D, Aly S, Ehlers S, et al
    Location of Persisting Mycobacteria in the Guinea Pig model of Tuberculosis revealed by R207910.
    Antimicrob Agents Chemother. 2007;.
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23. NGO SC , Zimhony O, Chung WJ, Sayahi H, et al
    Inhibition of Isolated Mycobacterium tuberculosis Fatty Acid Synthase I by Pyrazinamide Analogs.
    Antimicrob Agents Chemother. 2007;.
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    April 2007
24. STICKNEY DR , Noveljic Z, Garsd A, Destiche DA, et al
    Safety and activity of the immune modulator HE2000 on the incidence of tuberculosis and other opportunistic infections in AIDS patients.
    Antimicrob Agents Chemother. 2007;.
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25. RUSLAMI R , Nijland HM, Alisjahbana B, Parwati I, et al
    PHARMACOKINETICS AND TOLERABILITY OF A HIGHER RIFAMPICIN DOSE VERSUS THE STANDARD DOSE IN PULMONARY TUBERCULOSIS PATIENTS.
    Antimicrob Agents Chemother. 2007;.
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26. SIDDIQI S , Takhar P, Baldeviano C, Glover W, et al
    Isoniazid induces its own resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2007;.
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27. SHEN X , Shen GM, Wu J, Gui XH, et al
    The association between embB codon 306 mutations and drug resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2007;.
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28. NIKONENKO BV , Protopopova M, Samala R, Einck L, et al
    Drug therapy of experimental tuberculosis (TB): improved outcome by combining SQ109, a new diamine antibiotic, with existing TB drugs.
    Antimicrob Agents Chemother. 2007;51:1563-5.
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    February 2007
29. ZIMHONY O , Vilcheze C, Arai M, Welch JT, et al
    Pyrazinoic acid and its n-propyl ester inhibit fatty acid synthase type I in replicating tubercle bacilli.
    Antimicrob Agents Chemother. 2007;51:752-4.
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    January 2007
30. IONA E , Giannoni F, Pardini M, Brunori L, et al
    Metronidazole plus rifampin sterilize long-term dormant Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2007;.
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31. RICHTER E , Rusch-Gerdes S, Hillemann D
    First Linezolid-resistant Clinical Isolates of Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2007;.
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32. CHO SH , Warit S, Wan B, Hwang CH, et al
    Low oxygen recovery assay (LORA) for high throughput screening of compounds against non-replicating Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2007;.
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33. DAVIES GR , Pym AS, Mitchison DA, Nuermberger EL, et al
    Evaluation of new antituberculosis drugs in mouse models.
    Antimicrob Agents Chemother. 2007;51:403.
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    December 2006
34. HONGMANEE P , Rukseree K, Buabut B, Somsri B, et al
    In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2006;.
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35. IBRAHIM M , Andries K, Lounis N, Chauffour A, et al
    Synergistic activity of R207910 combined with pyrazinamide in murine tuberculosis.
    Antimicrob Agents Chemother. 2006;.
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36. SHANDIL RK , Jayaram R, Kaur P, Gaonkar S, et al
    Moxifloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against Mycobacterium tuberculosis: Evaluation of in vitro and pharmacodynamic indices that best predict in vivo efficacy.
    Antimicrob Agents Chemother. 2006;.
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37. BYRNE ST , Denkin SM, Zhang Y
    Aspirin antagonism in isonizaid treatment of tuberculosis in mice.
    Antimicrob Agents Chemother. 2006;.
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    November 2006
38. LOUNIS N , Veziris N, Chauffour A, Truffot-Pernot C, et al
    Combinations of R207910 with drugs used to treat multidrug-resistant tuberculosis have the potential to shorten treatment duration.
    Antimicrob Agents Chemother. 2006;50:3543-7.
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    October 2006
39. MATRAT S , Veziris N, Mayer C, Jarlier V, et al
    Functional analysis of DNA gyrase mutant enzymes carrying mutations at position 88 in the A subunit found in clinical strains of Mycobacterium tuberculosis resistant to fluoroquinolones.
    Antimicrob Agents Chemother. 2006;.
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    September 2006
40. VERA-CABRERA L , Gonzalez E, Rendon A, Ocampo-Candiani J, et al
    In Vitro Activities of DA-7157 and DA-7218 against Mycobacterium tuberculosis and Nocardia brasiliensis.
    Antimicrob Agents Chemother. 2006;50:3170-2.
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41. DAVIES GR , Brindle R, Khoo SH, Aarons LJ, et al
    Use of nonlinear mixed-effects analysis for improved precision of early pharmacodynamic measures in tuberculosis treatment.
    Antimicrob Agents Chemother. 2006;50:3154-6.
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    August 2006
42. HUITRIC E , Werngren J, Jureen P, Hoffner S, et al
    Resistance Levels and rpoB Gene Mutations among In Vitro-Selected Rifampin-Resistant Mycobacterium tuberculosis Mutants.
    Antimicrob Agents Chemother. 2006;50:2860-2.
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43. MALIK M , Drlica K
    Moxifloxacin Lethality against Mycobacterium tuberculosis in the Presence and Absence of Chloramphenicol.
    Antimicrob Agents Chemother. 2006;50:2842-4.
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44. GEIMAN DE , Raghunand TR, Agarwal N, Bishai WR, et al
    Differential Gene Expression in Response to Exposure to Antimycobacterial Agents and Other Stress Conditions among Seven Mycobacterium tuberculosis whiB-Like Genes.
    Antimicrob Agents Chemother. 2006;50:2836-41.
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45. MOKROUSOV I , Jiao WW, Sun GZ, Liu JW, et al
    Evolution of Drug Resistance in Different Sublineages of Mycobacterium tuberculosis Beijing Genotype.
    Antimicrob Agents Chemother. 2006;50:2820-3.
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46. WANG F , Cassidy C, Sacchettini JC
    Crystal Structure and Activity Studies of the Mycobacterium tuberculosis {beta}-Lactamase Reveal Its Critical Role in Resistance to {beta}-Lactam Antibiotics.
    Antimicrob Agents Chemother. 2006;50:2762-71.
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47. HAZBON MH , Brimacombe M, Bobadilla Del Valle M, Cavatore M, et al
    Population Genetics Study of Isoniazid Resistance Mutations and Evolution of Multidrug-Resistant Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2006;50:2640-9.
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48. NUERMBERGER E , Rosenthal I, Tyagi S, Williams KN, et al
    Combination Chemotherapy with the Nitroimidazopyran PA-824 and First-Line Drugs in a Murine Model of Tuberculosis.
    Antimicrob Agents Chemother. 2006;50:2621-5.
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    July 2006
49. ANDINI N , Nash KA
    Intrinsic Macrolide Resistance of the Mycobacterium tuberculosis Complex Is Inducible.
    Antimicrob Agents Chemother. 2006;50:2560-2562.
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    June 2006
50. SCHWARTZ YS , Dushkin MI, Vavilin VA, Melnikova EV, et al
    Novel Conjugate of Moxifloxacin and Carboxymethylated Glucan with Enhanced Activity against Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2006;50:1982-8.
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    May 2006
51. PLINKE C , Rusch-Gerdes S, Niemann S
    Significance of Mutations in embB Codon 306 for Prediction of Ethambutol Resistance in Clinical Mycobacterium tuberculosis Isolates.
    Antimicrob Agents Chemother. 2006;50:1900-2.
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52. O'RIORDAN K , Sharlin DS, Gross J, Chang S, et al
    Photoinactivation of Mycobacteria in vitro and in a new murine model of localized Mycobacterium bovis BCG-induced granulomatous infection.
    Antimicrob Agents Chemother. 2006;50:1828-34.
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    April 2006
53. GRUPPO V , Johnson CM, Marietta KS, Scherman H, et al
    Rapid Microbiologic and Pharmacologic Evaluation of Experimental Compounds against Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2006;50:1245-50.
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54. MCILLERON H , Wash P, Burger A, Norman J, et al
    Determinants of rifampin, isoniazid, pyrazinamide, and ethambutol pharmacokinetics in a cohort of tuberculosis patients.
    Antimicrob Agents Chemother. 2006;50:1170-7.
    PubMed     Related articles    Abstract available
    
    

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