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Articles published in J Clin Invest

Retrieve available abstracts of 44 articles:
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    January 2012
  1. HARRISON NJ
    Genetic instability in neural stem cells: an inconvenient truth?
    J Clin Invest. 2012 Jan 24. pii: 62002. doi: 10.1172/JCI62002.
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  2. VARELA C , Denis JA, Polentes J, Feyeux M, et al
    Recurrent genomic instability of chromosome 1q in neural derivatives of human embryonic stem cells.
    J Clin Invest. 2012 Jan 24. pii: 46268. doi: 10.1172/JCI46268.
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  3. SCHURCH C , Riether C, Matter MS, Tzankov A, et al
    CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression.
    J Clin Invest. 2012 Jan 9. pii: 45977. doi: 10.1172/JCI45977.
    PubMed     Text format     Related articles    Abstract available



    December 2011
  4. SAKAI K , Yamamoto A, Matsubara K, Nakamura S, et al
    Human dental pulp-derived stem cells promote locomotor recovery after complete transection of the rat spinal cord by multiple neuro-regenerative mechanisms.
    J Clin Invest. 2011 Dec 1. pii: 59251. doi: 10.1172/JCI59251.
    PubMed     Text format     Related articles    Abstract available



  5. MALATO Y , Naqvi S, Schurmann N, Ng R, et al
    Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration.
    J Clin Invest. 2011;121:4850-60.
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  6. GALIC S , Fullerton MD, Schertzer JD, Sikkema S, et al
    Hematopoietic AMPK beta1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity.
    J Clin Invest. 2011;121:4903-15.
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  7. WIEDE F , Shields BJ, Chew SH, Kyparissoudis K, et al
    T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice.
    J Clin Invest. 2011;121:4758-74.
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    November 2011
  8. TEPAVCEVIC V , Lazarini F, Alfaro-Cervello C, Kerninon C, et al
    Inflammation-induced subventricular zone dysfunction leads to olfactory deficits in a targeted mouse model of multiple sclerosis.
    J Clin Invest. 2011 Nov 7. pii: 59145. doi: 10.1172/JCI59145.
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  9. MURRAY SE , Polesso F, Rowe AM, Basak S, et al
    NF-kappaB-inducing kinase plays an essential T cell-intrinsic role in graft-versus-host disease and lethal autoimmunity in mice.
    J Clin Invest. 2011 Nov 1. pii: 44943. doi: 10.1172/JCI44943.
    PubMed     Text format     Related articles    Abstract available



    October 2011
  10. VOLCKAERT T , Dill E, Campbell A, Tiozzo C, et al
    Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.
    J Clin Invest. 2011 Oct 10. pii: 58097. doi: 10.1172/JCI58097.
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  11. KORKAYA H , Liu S, Wicha MS
    Breast cancer stem cells, cytokine networks, and the tumor microenvironment.
    J Clin Invest. 2011;121:3804-9.
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  12. WEBER C , Soehnlein O
    ApoE controls the interface linking lipids and inflammation in atherosclerosis.
    J Clin Invest. 2011;121:3825-7.
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    September 2011
  13. MURPHY AJ , Akhtari M, Tolani S, Pagler T, et al
    ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice.
    J Clin Invest. 2011 Sep 26. pii: 57559. doi: 10.1172/JCI57559.
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  14. LARANJEIRA C , Sandgren K, Kessaris N, Richardson W, et al
    Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury.
    J Clin Invest. 2011;121:3412-24.
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  15. JOSEPH NM , He S, Quintana E, Kim YG, et al
    Enteric glia are multipotent in culture but primarily form glia in the adult rodent gut.
    J Clin Invest. 2011;121:3398-411.
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  16. WU JY , Aarnisalo P, Bastepe M, Sinha P, et al
    Gsalpha enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice.
    J Clin Invest. 2011;121:3492-504.
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    August 2011
  17. GOERTZ MJ , Wu Z, Gallardo TD, Hamra FK, et al
    Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis.
    J Clin Invest. 2011 Aug 25. pii: 57984. doi: 10.1172/JCI57984.
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  18. XIE W , Fisher JT, Lynch TJ, Luo M, et al
    CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice.
    J Clin Invest. 2011;121:3144-58.
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  19. PASSEMARD S , El Ghouzzi V, Nasser H, Verney C, et al
    VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling.
    J Clin Invest. 2011;121:3071-87.
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    July 2011
  20. MCLEAN K , Gong Y, Choi Y, Deng N, et al
    Human ovarian carcinoma-associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production.
    J Clin Invest. 2011 Jul 1. pii: 45273. doi: 10.1172/JCI45273.
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  21. CLAIBORN K
    Federal funding for stem cell research: 15 years of indecision.
    J Clin Invest. 2011;121:2531.
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  22. CHAPMAN HA , Li X, Alexander JP, Brumwell A, et al
    Integrin alpha6beta4 identifies an adult distal lung epithelial population with regenerative potential in mice.
    J Clin Invest. 2011;121:2855-62.
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    June 2011
  23. MA H , Lu C, Ziegler J, Liu A, et al
    Absence of Stat1 in donor CD4+ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice.
    J Clin Invest. 2011 Jun 13. pii: 43706. doi: 10.1172/JCI43706.
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  24. NIVET E , Vignes M, Girard SD, Pierrisnard C, et al
    Engraftment of human nasal olfactory stem cells restores neuroplasticity in mice with hippocampal lesions.
    J Clin Invest. 2011 Jun 13. pii: 44489. doi: 10.1172/JCI44489.
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  25. MAROTTA LL , Almendro V, Marusyk A, Shipitsin M, et al
    The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24- stem cell-like breast cancer cells in human tumors.
    J Clin Invest. 2011 Jun 1. pii: 44745. doi: 10.1172/JCI44745.
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  26. BEERS MF , Morrisey EE
    The three R's of lung health and disease: repair, remodeling, and regeneration.
    J Clin Invest. 2011;121:2065-73.
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  27. RHEE YH , Ko JY, Chang MY, Yi SH, et al
    Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease.
    J Clin Invest. 2011;121:2326-35.
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  28. CHRISTODOULOU C , Longmire TA, Shen SS, Bourdon A, et al
    Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes.
    J Clin Invest. 2011;121:2313-25.
    PubMed     Text format     Related articles    Abstract available



  29. AUCAGNE R , Droin N, Paggetti J, Lagrange B, et al
    Transcription intermediary factor 1gamma is a tumor suppressor in mouse and human chronic myelomonocytic leukemia.
    J Clin Invest. 2011;121:2361-70.
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    May 2011
  30. EPSTEIN EH JR
    Mommy - where do tumors come from?
    J Clin Invest. 2011;121:1681-3.
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  31. PACHECO-PINEDO EC , Durham AC, Stewart KM, Goss AM, et al
    Wnt/beta-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.
    J Clin Invest. 2011;121:1935-45.
    PubMed     Text format     Related articles    Abstract available



    April 2011
  32. GRACHTCHOUK M , Pero J, Yang SH, Ermilov AN, et al
    Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.
    J Clin Invest. 2011 Apr 25. pii: 46307. doi: 10.1172/JCI46307.
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    March 2011
  33. SHIOZAWA Y , Pedersen EA, Havens AM, Jung Y, et al
    Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow.
    J Clin Invest. 2011 Mar 23. pii: 43414. doi: 10.1172/JCI43414.
    PubMed     Text format     Related articles    Abstract available



    February 2011
  34. NARSINH KH , Sun N, Sanchez-Freire V, Lee AS, et al
    Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells.
    J Clin Invest. 2011 Feb 7. pii: 44635. doi: 10.1172/JCI44635.
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  35. VARNUM-FINNEY B , Halasz LM, Sun M, Gridley T, et al
    Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells.
    J Clin Invest. 2011 Feb 1. pii: 43868. doi: 10.1172/JCI43868.
    PubMed     Text format     Related articles    Abstract available



  36. ECKARDT S , Leu NA, Yanchik A, Hatada S, et al
    Gene therapy by allele selection in a mouse model of beta-thalassemia.
    J Clin Invest. 2011;121:623-7.
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  37. ELKABETS M , Gifford AM, Scheel C, Nilsson B, et al
    Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice.
    J Clin Invest. 2011;121:784-99.
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  38. BATEMAN A
    Growing a tumor stroma: a role for granulin and the bone marrow.
    J Clin Invest. 2011;121:516-9.
    PubMed     Text format     Related articles    Abstract available



    January 2011
  39. NIJAGAL A , Wegorzewska M, Jarvis E, Le T, et al
    Maternal T cells limit engraftment after in utero hematopoietic cell transplantation in mice.
    J Clin Invest. 2011 Jan 18. pii: 44907. doi: 10.1172/JCI44907.
    PubMed     Text format     Related articles    Abstract available



  40. KREISEL D , Sugimoto S, Tietjens J, Zhu J, et al
    Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis.
    J Clin Invest. 2011;121:265-76.
    PubMed     Text format     Related articles    Abstract available



  41. ONOYAMA I , Suzuki A, Matsumoto A, Tomita K, et al
    Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver.
    J Clin Invest. 2011;121:342-54.
    PubMed     Text format     Related articles    Abstract available



    December 2010
  42. HARANDI OF , Hedge S, Wu DC, McKeone D, et al
    Murine erythroid short-term radioprotection requires a BMP4-dependent, self-renewing population of stress erythroid progenitors.
    J Clin Invest. 2010;120:4507-19.
    PubMed     Text format     Related articles    Abstract available



    November 2010
  43. MARROTTE EJ , Chen DD, Hakim JS, Chen AF, et al
    Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice.
    J Clin Invest. 2010 Nov 8. pii: 36858. doi: 10.1172/JCI36858.
    PubMed     Text format     Related articles    Abstract available



  44. SHINNICK KM , Eklund EA, McGarry TJ
    Geminin deletion from hematopoietic cells causes anemia and thrombocytosis in mice.
    J Clin Invest. 2010 Nov 1. pii: 43556. doi: 10.1172/JCI43556.
    PubMed     Text format     Related articles    Abstract available



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