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  Stem Cell Research

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Articles published in J Clin Invest

Retrieve available abstracts of 47 articles:
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Single Articles


    November 2017
  1. DE FEO D, Merlini A, Brambilla E, Ottoboni L, et al
    Neural precursor cell-secreted TGF-beta2 redirects inflammatory monocyte-derived cells in CNS autoimmunity.
    J Clin Invest. 2017;127:3937-3953.
    PubMed     Text format     Abstract available


    October 2017
  2. POULOS MG, Ramalingam P, Gutkin MC, Llanos P, et al
    Endothelial transplantation rejuvenates aged hematopoietic stem cell function.
    J Clin Invest. 2017 Oct 16. pii: 93940. doi: 10.1172/JCI93940.
    PubMed     Text format     Abstract available


  3. COLE CB, Russler-Germain DA, Ketkar S, Verdoni AM, et al
    Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies.
    J Clin Invest. 2017;127:3657-3674.
    PubMed     Text format     Abstract available


  4. TARNAWSKY SP, Chan RJ, Yoder MC
    Mice expressing KrasG12D in hematopoietic multipotent progenitor cells develop neonatal myeloid leukemia.
    J Clin Invest. 2017;127:3652-3656.
    PubMed     Text format     Abstract available


    September 2017
  5. PHILIPS T, Rothstein JD
    Oligodendroglia: metabolic supporters of neurons.
    J Clin Invest. 2017;127:3271-3280.
    PubMed     Text format     Abstract available


  6. KURODA M, Muramatsu R, Maedera N, Koyama Y, et al
    Peripherally derived FGF21 promotes remyelination in the central nervous system.
    J Clin Invest. 2017;127:3496-3509.
    PubMed     Text format     Abstract available


  7. YUAN H, Li N, Fu D, Ren J, et al
    Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis.
    J Clin Invest. 2017;127:3375-3391.
    PubMed     Text format     Abstract available


  8. HINO K, Horigome K, Nishio M, Komura S, et al
    Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.
    J Clin Invest. 2017;127:3339-3352.
    PubMed     Text format     Abstract available


  9. GOLDMAN SA
    Patience pays in spinal repair.
    J Clin Invest. 2017;127:3284-3286.
    PubMed     Text format     Abstract available


    August 2017
  10. MITROULIS I, Chen LS, Singh RP, Kourtzelis I, et al
    Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche.
    J Clin Invest. 2017 Aug 28. pii: 92571. doi: 10.1172/JCI92571.
    PubMed     Text format     Abstract available


  11. LU P, Ceto S, Wang Y, Graham L, et al
    Prolonged human neural stem cell maturation supports recovery in injured rodent CNS.
    J Clin Invest. 2017 Aug 21. pii: 92955. doi: 10.1172/JCI92955.
    PubMed     Text format     Abstract available


  12. OGURO H, McDonald JG, Zhao Z, Umetani M, et al
    27-Hydroxycholesterol induces hematopoietic stem cell mobilization and extramedullary hematopoiesis during pregnancy.
    J Clin Invest. 2017 Aug 7. pii: 94027. doi: 10.1172/JCI94027.
    PubMed     Text format     Abstract available


  13. WANG J, Cheng P, Pavlyukov MS, Yu H, et al
    Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
    J Clin Invest. 2017;127:3075-3089.
    PubMed     Text format     Abstract available


    June 2017
  14. MACDONALD KP, Blazar BR, Hill GR
    Cytokine mediators of chronic graft-versus-host disease.
    J Clin Invest. 2017;127:2452-2463.
    PubMed     Text format     Abstract available


  15. MATTE-MARTONE C, Liu J, Zhou M, Chikina M, et al
    Differential requirements for myeloid leukemia IFN-gamma conditioning determine graft-versus-leukemia resistance and sensitivity.
    J Clin Invest. 2017;127:2765-2776.
    PubMed     Text format     Abstract available


  16. XIA H, Gilbertsen A, Herrera J, Racila E, et al
    Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis.
    J Clin Invest. 2017;127:2586-2597.
    PubMed     Text format     Abstract available


  17. GIROUX V, Lento AA, Islam M, Pitarresi JR, et al
    Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration.
    J Clin Invest. 2017;127:2378-2391.
    PubMed     Text format     Abstract available


  18. ELAGIB KE, Lu CH, Mosoyan G, Khalil S, et al
    Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition.
    J Clin Invest. 2017;127:2365-2377.
    PubMed     Text format     Abstract available


  19. NIEBOROWSKA-SKORSKA M, Sullivan K, Dasgupta Y, Podszywalow-Bartnicka P, et al
    Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.
    J Clin Invest. 2017;127:2392-2406.
    PubMed     Text format     Abstract available


  20. GASKILL CF, Carrier EJ, Kropski JA, Bloodworth NC, et al
    Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction.
    J Clin Invest. 2017;127:2262-2276.
    PubMed     Text format     Abstract available


    May 2017
  21. LEE J, Dykstra B, Spencer JA, Kenney LL, et al
    mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors.
    J Clin Invest. 2017 May 8. pii: 92030. doi: 10.1172/JCI92030.
    PubMed     Text format     Abstract available


  22. HAWKINS F, Kramer P, Jacob A, Driver I, et al
    Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells.
    J Clin Invest. 2017 May 2. pii: 89950. doi: 10.1172/JCI89950.
    PubMed     Text format     Abstract available


  23. HEBBEL RP
    Blood endothelial cells: utility from ambiguity.
    J Clin Invest. 2017;127:1613-1615.
    PubMed     Text format     Abstract available


    April 2017
  24. BRUCE DW, Stefanski HE, Vincent BG, Dant TA, et al
    Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease.
    J Clin Invest. 2017 Apr 4. pii: 91816. doi: 10.1172/JCI91816.
    PubMed     Text format     Abstract available


  25. TEVERONI E, Pellegrino M, Sacconi S, Calandra P, et al
    Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity.
    J Clin Invest. 2017;127:1531-1545.
    PubMed     Text format     Abstract available


    March 2017
  26. SHAW KL, Garabedian E, Mishra S, Barman P, et al
    Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency.
    J Clin Invest. 2017 Mar 27. pii: 90367. doi: 10.1172/JCI90367.
    PubMed     Text format     Abstract available


  27. KALAITZIDIS D, Lee D, Efeyan A, Kfoury Y, et al
    Amino acid-insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells.
    J Clin Invest. 2017 Mar 20. pii: 89452. doi: 10.1172/JCI89452.
    PubMed     Text format     Abstract available


  28. AMSEN D
    T cells take directions from supporting cast in graft-versus-host disease.
    J Clin Invest. 2017 Mar 20. pii: 93552. doi: 10.1172/JCI93552.
    PubMed     Text format     Abstract available


  29. GRIFFIN CT, Gao S
    Building discontinuous liver sinusoidal vessels.
    J Clin Invest. 2017;127:790-792.
    PubMed     Text format     Abstract available


  30. WHITTAKER DE, Riegman KL, Kasah S, Mohan C, et al
    The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression.
    J Clin Invest. 2017;127:874-887.
    PubMed     Text format     Abstract available


    February 2017
  31. LI H, Liu P, Xu S, Li Y, et al
    FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
    J Clin Invest. 2017 Feb 27. pii: 89511. doi: 10.1172/JCI89511.
    PubMed     Text format     Abstract available


  32. OSUKA S, Van Meir EG
    Overcoming therapeutic resistance in glioblastoma: the way forward.
    J Clin Invest. 2017;127:415-426.
    PubMed     Text format     Abstract available


  33. ABARRATEGI A, Foster K, Hamilton A, Mian SA, et al
    Versatile humanized niche model enables study of normal and malignant human hematopoiesis.
    J Clin Invest. 2017;127:543-548.
    PubMed     Text format     Abstract available


    October 2016
  34. GERBY B, Veiga DF, Krosl J, Nourreddine S, et al
    High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.
    J Clin Invest. 2016 Oct 31. pii: 86489. doi: 10.1172/JCI86489.
    PubMed     Text format     Abstract available


    September 2016
  35. JIN Y, Zhou J, Xu F, Jin B, et al
    Targeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia.
    J Clin Invest. 2016 Sep 19. pii: 85239. doi: 10.1172/JCI85239.
    PubMed     Text format     Abstract available


    August 2016
  36. ZHOU V, Agle K, Chen X, Beres A, et al
    A colitogenic memory CD4+ T cell population mediates gastrointestinal graft-versus-host disease.
    J Clin Invest. 2016 Aug 8. pii: 80874. doi: 10.1172/JCI80874.
    PubMed     Text format     Abstract available


  37. YOU L, Li L, Zou J, Yan K, et al
    BRPF1 is essential for development of fetal hematopoietic stem cells.
    J Clin Invest. 2016 Aug 8. pii: 80711. doi: 10.1172/JCI80711.
    PubMed     Text format     Abstract available


    June 2016
  38. FAN X
    gamma-Secretase inhibitor-resistant glioblastoma stem cells require RBPJ to propagate.
    J Clin Invest. 2016 Jun 20. pii: 88619. doi: 10.1172/JCI88619.
    PubMed     Text format     Abstract available


  39. SAHA A, O'Connor RS, Thangavelu G, Lovitch SB, et al
    Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.
    J Clin Invest. 2016 Jun 13. pii: 85796. doi: 10.1172/JCI85796.
    PubMed     Text format     Abstract available


  40. GHOSH J, Kobayashi M, Ramdas B, Chatterjee A, et al
    S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance.
    J Clin Invest. 2016 Jun 13. pii: 84565. doi: 10.1172/JCI84565.
    PubMed     Text format     Abstract available


    April 2016
  41. ZHANG ZG, Chopp M
    Exosomes in stroke pathogenesis and therapy.
    J Clin Invest. 2016;126:1190-7.
    PubMed     Text format     Abstract available


  42. LIU L, Rando TA
    UTX in muscle regeneration--the right dose and the right time.
    J Clin Invest. 2016;126:1233-5.
    PubMed     Text format     Abstract available


  43. FARALLI H, Wang C, Nakka K, Benyoucef A, et al
    UTX demethylase activity is required for satellite cell-mediated muscle regeneration.
    J Clin Invest. 2016;126:1555-65.
    PubMed     Text format     Abstract available


  44. CHENG Y, Chikwava K, Wu C, Zhang H, et al
    LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors.
    J Clin Invest. 2016;126:1267-81.
    PubMed     Text format     Abstract available


  45. PALANICHAMY JK, Tran TM, Howard JM, Contreras JR, et al
    RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation.
    J Clin Invest. 2016;126:1495-511.
    PubMed     Text format     Abstract available


  46. WANG C, Inzana JA, Mirando AJ, Ren Y, et al
    NOTCH signaling in skeletal progenitors is critical for fracture repair.
    J Clin Invest. 2016;126:1471-81.
    PubMed     Text format     Abstract available


    March 2016
  47. OHMURA S, Mizuno S, Oishi H, Ku CJ, et al
    Lineage-affiliated transcription factors bind the Gata3 Tce1 enhancer to mediate lineage-specific programs.
    J Clin Invest. 2016;126:865-78.
    PubMed     Text format     Abstract available


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