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By B. S. Kamps et al.


  Stem Cell Research

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Articles published in Blood

Retrieve available abstracts of 169 articles:
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Single Articles


    March 2024
  1. WILKINSON AC
    Take the MYC to expand blood stem cells.
    Blood. 2024;143:838-840.
    PubMed    


  2. SACCO A, Roccaro AM
    Waking up exhausted BCMA-specific T cells in myeloma.
    Blood. 2024;143:840-841.
    PubMed    



  3. Colom Diaz PA, Mistry JJ, Trowbridge JJ. Hematopoietic stem cell aging and leukemia transformation. Blood. 2023;142(6):533-542.
    Blood. 2024;143:939.
    PubMed    


    February 2024
  4. MURTADHA M, Park M, Zhu Y, Caserta E, et al
    CD38-directed, single-chain T cell-engager targets leukemia stem cells through IFNgamma-induced CD38 expression.
    Blood. 2024 Feb 26:blood.2023021570. doi: 10.1182/blood.2023021570.
    PubMed     Abstract available


  5. FISKUS W, Piel J, Collins MP, Hentemann M, et al
    BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor.
    Blood. 2024 Feb 16:blood.2023022832. doi: 10.1182/blood.2023022832.
    PubMed     Abstract available


  6. KIM OV, Litvinov RI, Gagne AL, French DL, et al
    Megakaryocyte-induced contraction of plasma clots: cellular mechanisms and structural mechanobiology.
    Blood. 2024;143:548-560.
    PubMed     Abstract available


    January 2024
  7. TAKAHASHI S, Minnie SA, Ensbey KS, Schmidt CR, et al
    Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation.
    Blood. 2024 Jan 31:blood.2023022000. doi: 10.1182/blood.2023022000.
    PubMed     Abstract available


  8. GU H, Chen C, Hou ZS, He XD, et al
    PI3Kgamma maintains the self-renewal of acute myeloid leukemia stem cells by regulating the pentose phosphate pathway.
    Blood. 2024 Jan 25:blood.2023022202. doi: 10.1182/blood.2023022202.
    PubMed     Abstract available


  9. UEHATA T, Yamada S, Ori D, Vandenbon A, et al
    Regulation of lymphoid-myeloid lineage bias through regnase-1/3-mediated control of Nfkbiz.
    Blood. 2024;143:243-257.
    PubMed     Abstract available


  10. KHANDELWAL P, Langenberg L, Luebbering N, Lake K, et al
    A randomized phase 2 trial of oral vitamin A for graft-versus-host disease in children and young adults.
    Blood. 2024 Jan 16:blood.2023022865. doi: 10.1182/blood.2023022865.
    PubMed     Abstract available


  11. LYNCH J, Troadec E, Fung TK, Gladysz K, et al
    Hematopoietic stem cell quiescence and DNA replication dynamics maintained by the resilient beta-catenin/Hoxa9/Prmt1 axis.
    Blood. 2024 Jan 11:blood.2023022082. doi: 10.1182/blood.2023022082.
    PubMed     Abstract available


  12. CHAGRAOUI J, Girard S, Mallinger L, Mayotte N, et al
    KBTBD4-mediated Reduction of MYC Is Critical For Hematopoietic Stem Cell Expansion Upon UM171 Treatment.
    Blood. 2024 Jan 11:blood.2023021342. doi: 10.1182/blood.2023021342.
    PubMed     Abstract available


  13. KHANNA R, Gandhi MK
    EBV-infected hematopoietic stem cells drive CAEBV.
    Blood. 2024;143:2-4.
    PubMed    


    December 2023
  14. SARACHAKOV A, Varlamova A, Svekolkin V, Polyakova M, et al
    Spatial mapping of human hematopoiesis at single-cell resolution reveals aging-associated topographic remodeling.
    Blood. 2023;142:2282-2295.
    PubMed     Abstract available


  15. DIMITRIOU M, Mortera-Blanco T, Tobiasson M, Mazzi S, et al
    Identification and surveillance of rare relapse-initiating stem cells during complete remission post-transplantation.
    Blood. 2023 Dec 14:blood.2023022851. doi: 10.1182/blood.2023022851.
    PubMed     Abstract available


  16. ADAMS RC, Carter-Cusack D Mr, Llanes GT, Hunter CR, et al
    CSF1R inhibition promotes neuroinflammation and behavioural deficits during graft-versus-host disease in mice.
    Blood. 2023 Dec 4:blood.2023022040. doi: 10.1182/blood.2023022040.
    PubMed     Abstract available


    November 2023
  17. XIE SZ
    Sphingolipids and HSC fitness: enigma no more.
    Blood. 2023;142:1674-1676.
    PubMed    


  18. BUENO C, Torres-Ruiz R, Velasco-Hernandez T, Molina O, et al
    A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features.
    Blood. 2023;142:1752-1756.
    PubMed     Abstract available


  19. JODELE S, Dandoy CE, Aguayo-Hiraldo P, Lane A, et al
    Prospective Multi-Institutional Study of Eculizumab to Treat High-Risk Stem Cell Transplant Associated TMA.
    Blood. 2023 Nov 9:blood.2023022526. doi: 10.1182/blood.2023022526.
    PubMed     Abstract available


  20. ZHANG S, Pinho S
    Untangling the role of KIT ligand in HSC regulation.
    Blood. 2023;142:1581-1582.
    PubMed    


    October 2023
  21. BAE J, Kitayama S, Herbert Z, Daheron L, et al
    Differentiation of BCMA-specific induced pluripotent stem cells into CD8alphabeta+ T cells targeting multiple myeloma.
    Blood. 2023 Oct 27:blood.2023020528. doi: 10.1182/blood.2023020528.
    PubMed     Abstract available


  22. SUBRAMANIAN S, Thoms JAI, Huang Y, Cornejo-Paramo P, et al
    Genome-wide transcription factor-binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs.
    Blood. 2023;142:1448-1462.
    PubMed     Abstract available


  23. MASETTI R, Leardini D, Muratore E, Fabbrini M, et al
    Gut microbiota diversity before allogeneic hematopoietic stem cell transplantation as a predictor of mortality in children.
    Blood. 2023;142:1387-1398.
    PubMed     Abstract available


  24. WANG J, Su M, Wei N, Yan H, et al
    Chronic Active Epstein-Barr Virus Disease Originates from Infected Hematopoietic Stem Cells.
    Blood. 2023 Oct 12:blood.2023021074. doi: 10.1182/blood.2023021074.
    PubMed     Abstract available


    September 2023
  25. TANG B, Wang X, He H, Chen R, et al
    Aging-disturbed FUS Phase Transition Impairs Hematopoietic Stem Cell by Altering Chromatin Structure.
    Blood. 2023 Sep 25:blood.2023020539. doi: 10.1182/blood.2023020539.
    PubMed     Abstract available


  26. CARTER BZ, Mak PY, Muftuoglu M, Tao W, et al
    Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells.
    Blood. 2023;142:1056-1070.
    PubMed     Abstract available


  27. HURWITZ SN, Jung SK, Kobulsky DR, Fazelinia H, et al
    Neutral sphingomyelinase blockade enhances hematopoietic stem cell fitness through an integrated stress response.
    Blood. 2023 Sep 12:blood.2023022147. doi: 10.1182/blood.2023022147.
    PubMed     Abstract available


    August 2023
  28. VAVASSORI V, Ferrari S, Beretta S, Asperti C, et al
    Lipid nanoparticles allow efficient and harmless ex vivo gene editing of human hematopoietic cells.
    Blood. 2023;142:812-826.
    PubMed     Abstract available


  29. RHEE C, Scadden EW, Wong LP, Schiroli G, et al
    Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors.
    Blood. 2023;142:658-674.
    PubMed     Abstract available


  30. WU L, Lin Q, Chatla S, Amarachintha SP, et al
    LepR+ niche cell-derived AREG compromises hematopoietic stem cell maintenance under conditions of DNA repair deficiency and aging.
    Blood. 2023 Aug 15:blood.2022018212. doi: 10.1182/blood.2022018212.
    PubMed     Abstract available


  31. SEZAKI M, Huang G
    Food for thought (and CML survival).
    Blood. 2023;142:502-504.
    PubMed    


  32. CRISPINO JD
    Introduction to a review series on hematopoietic stem cells.
    Blood. 2023;142:497.
    PubMed    


  33. MATSUOKA S, Facchini R, Luis TC, Carrelha J, et al
    Loss of endothelial membrane KIT Ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells.
    Blood. 2023 Aug 10:blood.2022019018. doi: 10.1182/blood.2022019018.
    PubMed     Abstract available


  34. FENG J, Hsu PF, Esteva E, Labella R, et al
    Haplodeficiency of the 9p21 tumor suppressor locus causes myeloid disorders driven by the bone marrow microenvironment.
    Blood. 2023;142:460-476.
    PubMed     Abstract available


  35. GOTZE KS
    Flipping the switch in the stem cell niche.
    Blood. 2023;142:404-406.
    PubMed    


    July 2023
  36. LABROSSE R, Chu J, Armant M, Everett JK, et al
    Outcomes of Hematopoietic Stem Cell Gene Therapy for Wiskott-Aldrich Syndrome.
    Blood. 2023 Jul 21:blood.2022019117. doi: 10.1182/blood.2022019117.
    PubMed     Abstract available


  37. VELOSO A, Cools J
    Targeting STAT5B in T-cell acute lymphoblastic leukemia.
    Blood. 2023;142:215-217.
    PubMed    


  38. BAMEZAI S, Pulikkottil AJ, Yadav T, Vegi NM, et al
    A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML.
    Blood. 2023;142:90-105.
    PubMed     Abstract available


  39. RADTKE S, Enstrom M, Pande D, Duke ER, et al
    Stochastic fate decisions of HSCs after transplantation: early contribution, symmetric expansion, and pool formation.
    Blood. 2023;142:33-43.
    PubMed     Abstract available


    June 2023
  40. CALVANESE V, Mikkola H
    The genesis of human hematopoietic stem cells.
    Blood. 2023 Jun 20:blood.2022017934. doi: 10.1182/blood.2022017934.
    PubMed     Abstract available


  41. MERRILL MH, Dahi PB, Redd RA, McDonough M, et al
    A Phase 2 Study of pembrolizumab after Autologous Stem Cell Transplantation in Patients with T-Cell non-Hodgkin Lymphoma.
    Blood. 2023 Jun 15:blood.2023020244. doi: 10.1182/blood.2023020244.
    PubMed     Abstract available


    May 2023
  42. MUNZ CM, Dressel N, Chen M, Grinenko T, et al
    Regeneration after blood loss and acute inflammation proceeds without contribution of primitive HSCs.
    Blood. 2023;141:2483-2492.
    PubMed     Abstract available


  43. QIU S, Sheth VS, Yan C, Liu J, et al
    Metabolic Adaptation to Tyrosine Kinase Inhibition in Leukemia Stem Cells.
    Blood. 2023 May 16:blood.2022018196. doi: 10.1182/blood.2022018196.
    PubMed     Abstract available



  44. Albert MH, Sirait T, Eikema D-J, et al. Hematopoietic stem cell transplantation for adolescents and adults with inborn errors of immunity: an EBMT IEWP study. Blood. 2022;140(14):1635-1649.
    Blood. 2023;141:2284.
    PubMed    


    April 2023
  45. LI C, Georgakopoulou A, Newby GA, Chen PJ, et al
    In vivo HSC prime editing rescues sickle cell disease in a mouse model.
    Blood. 2023;141:2085-2099.
    PubMed     Abstract available


  46. GONDA TJ
    MYB deficiency leads to myeloid neoplasia too.
    Blood. 2023;141:1786-1787.
    PubMed    


  47. PIETRAS EM
    Young bugs rejuvenate old blood.
    Blood. 2023;141:1650-1652.
    PubMed    


  48. ANJOS-AFONSO F, Bonnet D
    Human CD34+ hematopoietic stem cell hierarchy: how far are we with its delineation at the most primitive level?
    Blood. 2023 Apr 5:blood.2022018071. doi: 10.1182/blood.2022018071.
    PubMed     Abstract available


  49. DOLINSKA M, Cai H, Mansson A, Shen J, et al
    Characterization of Bone Marrow Niche in Chronic Myeloid Leukemia Patients Identifies CXCL14 as a New Therapeutic Option.
    Blood. 2023 Apr 5:blood.2022016896. doi: 10.1182/blood.2022016896.
    PubMed     Abstract available


    March 2023
  50. TREMBLAY CS, Saw J, Boyle JA, Haigh K, et al
    STAT5 activation promotes progression and chemotherapy-resistance in early T-cell precursor acute lymphoblastic leukemia.
    Blood. 2023 Mar 29:blood.2022016322. doi: 10.1182/blood.2022016322.
    PubMed     Abstract available


  51. ZHAO HG, Deininger MW
    ALWAYS STRESSED BUT NEVER EXHAUSTED: HOW STEM CELLS IN MYELOID NEOPLASMS AVOID EXTINCTION IN INFLAMMATORY CONDITIONS.
    Blood. 2023 Mar 22:blood.2022017152. doi: 10.1182/blood.2022017152.
    PubMed     Abstract available


  52. GAGELMANN N, Badbaran A, Salit RB, Schroeder T, et al
    Impact of TP53 on outcome of patients with myelofibrosis undergoing hematopoietic stem cell transplantation.
    Blood. 2023 Mar 20:blood.2023019630. doi: 10.1182/blood.2023019630.
    PubMed     Abstract available


  53. SCHNEGG-KAUFMANN AS, Thoms JAI, Bhuyan GS, Hampton HR, et al
    Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy.
    Blood. 2023;141:1316-1321.
    PubMed     Abstract available


  54. NGAI LL, Hanekamp D, Janssen F, Carbaat-Ham J, et al
    Prospective Validation of the Prognostic Relevance of CD34+CD38- AML Stem Cell frequency in the HOVON-SAKK132 trial.
    Blood. 2023 Mar 10:blood.2022019160. doi: 10.1182/blood.2022019160.
    PubMed    



  55. Burgos da Silva M, Ponce DM, Dai A, et al. Preservation of the fecal microbiome is associated with reduced severity of graft-versus-host disease. Blood. 2022;140(22):2385-2397.
    Blood. 2023;141:1234.
    PubMed    


  56. KOSHY AG, Kim HT, Liegel J, Arnason JE, et al
    Phase II clinical trial evaluating Abatacept in patients with steroid-refractory chronic graft versus host disease.
    Blood. 2023 Mar 2:blood.2022019107. doi: 10.1182/blood.2022019107.
    PubMed     Abstract available


    February 2023

  57. Lopez de Lapuente Portilla A, Ekdahl L, Cafaro C, et al. Genome-wide association study on 13 167 individuals identifies regulators of blood CD34+ cell levels. Blood. 2022;139(11):1659-1669.
    Blood. 2023;141:962.
    PubMed    


  58. CICHOCKI F, van der Stegen SJC, Miller JS
    Engineered and banked iPSCs for advanced NK- and T-cell immunotherapies.
    Blood. 2023;141:846-855.
    PubMed     Abstract available


  59. COLOM DIAZ PA, Mistry JJ, Trowbridge JJ
    Hematopoietic Stem Cell Aging and Leukemia Transformation.
    Blood. 2023 Feb 17:blood.2022017933. doi: 10.1182/blood.2022017933.
    PubMed     Abstract available


  60. LINDER MI, Mizoguchi Y, Hesse S, Csaba G, et al
    Human genetic defects in SRP19 and SRPRA cause severe congenital neutropenia with distinctive proteome changes.
    Blood. 2023;141:645-658.
    PubMed     Abstract available


  61. JASSINSKAJA M, Gonka M, Kent D
    Resolving the hematopoietic stem cell state by linking functional and molecular assays.
    Blood. 2023 Feb 3:blood.2022017864. doi: 10.1182/blood.2022017864.
    PubMed     Abstract available


    January 2023
  62. HAMMOND CA, Wu SW, Wang F, MacAldaz ME, et al
    Aging alters the cell cycle control and mitogenic signaling responses of human hematopoietic stem cells.
    Blood. 2023 Jan 18:blood.2022017174. doi: 10.1182/blood.2022017174.
    PubMed     Abstract available


  63. ZENG X, Li X, Li X, Wei C, et al
    Fecal microbiota transplantation from young mice rejuvenates aged hematopoietic stem cells by suppressing inflammation.
    Blood. 2023 Jan 13:blood.2022017514. doi: 10.1182/blood.2022017514.
    PubMed     Abstract available


  64. RATTIGAN KM, Zarou MM, Helgason V
    Metabolism in stem cell driven leukaemia: parallels between haematopoiesis and immunity.
    Blood. 2023 Jan 12:blood.2022018258. doi: 10.1182/blood.2022018258.
    PubMed     Abstract available


  65. CLARKE ML, Lemma RB, Walton DS, Volpe G, et al
    MYB insufficiency disrupts proteostasis in hematopoietic stem cells leading to age-related neoplasia.
    Blood. 2023 Jan 5:blood.2022019138. doi: 10.1182/blood.2022019138.
    PubMed     Abstract available


    December 2022
  66. CHENG Q, Wang D, Lai X, Liu Y, et al
    The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.
    Blood. 2022 Dec 27:blood.2022017201. doi: 10.1182/blood.2022017201.
    PubMed     Abstract available



  67. Lehnertz B, Chagraoui J, MacRae T, et al. HLF expression defines the human hematopoietic stem cell state. Blood. 2021;138(25):2642-2654.
    Blood. 2022;140:2761.
    PubMed    


  68. GREENBERG ZJ, Monlish D, Chiquetto Paracatu L, Dong Q, et al
    The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex- mediated quiescence.
    Blood. 2022 Dec 21:blood.2022016929. doi: 10.1182/blood.2022016929.
    PubMed     Abstract available


  69. RAHNAMA R, Bonifant CL
    Engineering builds multipotency for iPSC-NKs.
    Blood. 2022;140:2414-2416.
    PubMed    


  70. XIA L
    Engineered platelets for clinical application: a step closer.
    Blood. 2022;140:2314-2315.
    PubMed    


  71. SULLIVAN JC, Comenzo R
    Peripheral agglutination and hemolytic anemia following minor ABO-mismatch hematopoietic progenitor cell transplantation.
    Blood. 2022;140:2412.
    PubMed    


  72. SUGIMOTO N, Kanda J, Nakamura S, Kitano T, et al
    iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study.
    Blood. 2022;140:2398-2402.
    PubMed    


  73. HSIEH HH, Yao H, Ma Y, Zhang Y, et al
    Epo-IGF1R cross talk expands stress-specific progenitors in regenerative erythropoiesis and myeloproliferative neoplasm.
    Blood. 2022;140:2371-2384.
    PubMed     Abstract available


    November 2022
  74. COOPER JP, Abkowitz JL
    How we diagnose and treat acute graft-versus-host disease after solid organ transplantation.
    Blood. 2022 Nov 17. pii: 493251. doi: 10.1182/blood.2022015954.
    PubMed     Abstract available


  75. MENENDEZ-GUTIERREZ MP, Porcuna J, Nayak RC, Paredes A, et al
    Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homeostasis.
    Blood. 2022 Nov 8. pii: 487046. doi: 10.1182/blood.2022016832.
    PubMed     Abstract available


    October 2022
  76. SPERLING AS, Guerra VA, Kennedy JA, Yan Y, et al
    Lenalidomide promotes the development of TP53-mutated therapy-related myeloid neoplasms.
    Blood. 2022;140:1753-1763.
    PubMed     Abstract available


  77. KOYAMA M, Samson L, Ensbey KS, Takahashi S, et al
    Lithium attenuates graft-versus-host disease via effects on the intestinal stem cell niche.
    Blood. 2022 Oct 6. pii: 486737. doi: 10.1182/blood.2022015808.
    PubMed    


  78. LI S, Yao JC, Oetjen KA, Krambs JR, et al
    IL-1beta expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function.
    Blood. 2022;140:1607-1620.
    PubMed     Abstract available


    September 2022
  79. CHUTE JP
    Tet2 helps blood cells balance in air.
    Blood. 2022;140:1186-1187.
    PubMed    


  80. ZHANG YW, Cabezas-Wallscheid N
    HSCs: slow me down with PLAG1.
    Blood. 2022;140:935-936.
    PubMed    


    August 2022
  81. MO F, Watanabe N, Ingersoll Omdahl K, Burkhardt PM, et al
    Engineering T cells to suppress acute GvHD and leukemia relapse after allogeneic hematopoietic stem cell transplantation.
    Blood. 2022 Aug 31. pii: 486464. doi: 10.1182/blood.2022016052.
    PubMed     Abstract available


  82. VAN HALTEREN AGS, Suwandi J, Tuit S, Borst J, et al
    A UNIQUE IMMUNE SIGNATURE IN BLOOD SEPARATES THERAPY-REFRACTORY FROM THERAPY-RESPONSIVE ACUTE GRAFT-VERSUS-HOST DISEASE.
    Blood. 2022 Aug 31. pii: 486465. doi: 10.1182/blood.2022015734.
    PubMed     Abstract available


  83. HULBERT ML, Fields ME, Guilliams KP, Bijlani P, et al
    Normalization of cerebral hemodynamics following hematopoietic stem cell transplant in children with sickle cell disease.
    Blood. 2022 Aug 30. pii: 486449. doi: 10.1182/blood.2022016618.
    PubMed     Abstract available


  84. VALLET N, Le Grand S, Bondeelle L, Hoareau B, et al
    Azithromycin promotes relapse by disrupting immune and metabolic networks after allogeneic stem cell transplantation.
    Blood. 2022 Aug 19. pii: 486351. doi: 10.1182/blood.2022016926.
    PubMed     Abstract available


  85. WANG J, Chang CY, Yang X, Zhou F, et al
    Leukemia inhibitory factor protects against graft-versus-host disease while preserving graft-versus-leukemia activity.
    Blood. 2022 Aug 18. pii: 486317. doi: 10.1182/blood.2022015677.
    PubMed     Abstract available


  86. AN HH, Gagne AL, Maguire JA, Pavani G, et al
    The use of pluripotent stem cells to generate diagnostic tools for transfusion medicine.
    Blood. 2022 Aug 17. pii: 486282. doi: 10.1182/blood.2022015883.
    PubMed     Abstract available


  87. BURGOS DA SILVA M, Ponce DM, Dai A, Devlin SM, et al
    Preservation of fecal microbiome is associated with reduced severity of Graft-versus-Host Disease.
    Blood. 2022 Aug 15. pii: 486225. doi: 10.1182/blood.2021015352.
    PubMed     Abstract available


  88. CHEMINANT M, Fox TA, Alligon M, Bouaziz O, et al
    Allogeneic stem cell transplantation compared to conservative management in adults with inborn errors of immunity.
    Blood. 2022 Aug 10. pii: 486184. doi: 10.1182/blood.2022015482.
    PubMed     Abstract available


  89. HOLMES ZC, Tang H, Liu C, Bush AT, et al
    Prebiotic galactooligosaccharides interact with mouse gut microbiota to attenuate acute graft-versus-host disease.
    Blood. 2022 Aug 5. pii: 486126. doi: 10.1182/blood.2021015178.
    PubMed    


  90. MAO X, Li L
    p57Kip2 indirectly regulates AGM HSCs.
    Blood. 2022;140:411-412.
    PubMed    


    July 2022
  91. LI C, Wu B, Li Y, Liu Y, et al
    Loss of sphingosine kinase 2 promotes the expansion of hematopoietic stem cells by improving their metabolic fitness.
    Blood. 2022 Jul 26. pii: 486023. doi: 10.1182/blood.2022016112.
    PubMed     Abstract available


  92. KULL T, Wehling A, Etzrodt M, Auler M, et al
    NfkappaB signaling dynamics and their target genes differ between mouse blood cell types and induce distinct cell behavior.
    Blood. 2022;140:99-111.
    PubMed     Abstract available


  93. WEHLING A, Loeffler D, Zhang Y, Kull T, et al
    Combined single-cell tracking and omics improves blood stem cell fate regulator identification.
    Blood. 2022 Jul 12. pii: 485878. doi: 10.1182/blood.2022016880.
    PubMed     Abstract available


    June 2022
  94. ALJOUFI A, Zhang C, Ropa J, Chang W, et al
    Physioxia induced Downregulation of Tet2 in Hematopoietic Stem Cells contributes to Enhanced Self-renewal.
    Blood. 2022 Jun 30. pii: 485747. doi: 10.1182/blood.2022015499.
    PubMed     Abstract available


  95. LI J, Williams MJ, Park HJ, Bastos HP, et al
    STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resists myeloablation and neoplastic expansion.
    Blood. 2022 Jun 29. pii: 485724. doi: 10.1182/blood.2021014009.
    PubMed     Abstract available



  96. Liu Y, Chen Q, Jeong H-W, et al. Dopamine signaling regulates hematopoietic stem and progenitor cell function. Blood. 2021;138(21):2051-2065.
    Blood. 2022;139:3668.
    PubMed    


  97. LI B, An W, Wang H, Baslan T, et al
    BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation.
    Blood. 2022;139:3630-3646.
    PubMed     Abstract available


  98. GALLAGHER PG
    Extramedullary hematopoietic stem cells.
    Blood. 2022;139:3353-3354.
    PubMed    


  99. MENDE N, Bastos HP, Santoro A, Mahbubani KT, et al
    Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans.
    Blood. 2022;139:3387-3401.
    PubMed     Abstract available


  100. KAPENI C, Nitsche L, Kilpatrick AM, Wilson NK, et al
    p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion.
    Blood. 2022 Jun 2. pii: 485456. doi: 10.1182/blood.2021014853.
    PubMed     Abstract available



  101. Henden AS, Koyama M, Robb RJ, et al. IFN-lambda therapy prevents severe gastrointestinal graft-versus-host disease. Blood. 2021;138(8):722-737.
    Blood. 2022;139:3346-3351.
    PubMed    



  102. Yu Z, Yang W, He X, et al. Endothelial cell-derived angiopoietin-like protein 2 supports hematopoietic stem cell activities in bone marrow niches. Blood. 2022;139(10):1529-1540.
    Blood. 2022;139:3352.
    PubMed    


  103. DAVENPORT P, Liu ZJ, Sola-Visner M
    Fetal vs adult megakaryopoiesis.
    Blood. 2022;139:3233-3244.
    PubMed     Abstract available


  104. TILBURG J, Becker IC, Italiano JE
    Don't you forget about me(gakaryocytes).
    Blood. 2022;139:3245-3254.
    PubMed     Abstract available


    May 2022
  105. KEYVANI CHAHI A, Belew MS, Xu J, Chen HTT, et al
    PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal.
    Blood. 2022 May 31. pii: 485426. doi: 10.1182/blood.2021014698.
    PubMed     Abstract available


  106. MENDEZ-FERRER S
    RIG-Ing out BMSCs for hematopoietic recovery after transplantation.
    Blood. 2022;139:3107-3109.
    PubMed    


  107. YANG Y, Mumau M, Tober J, Zhu Q, et al
    Endothelial MEKK3-KLF2/4 signaling integrates inflammatory and hemodynamic signals during definitive hematopoiesis.
    Blood. 2022;139:2942-2957.
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    April 2022
  108. ZHU J, Wang Y, Li JX, Das PK, et al
    Donor Plasmacytoid Dendritic Cells Limit Graft-versus-Host Disease Through Vasoactive Intestinal Polypeptide Expression.
    Blood. 2022 Apr 20. pii: 485002. doi: 10.1182/blood.2021012561.
    PubMed     Abstract available


  109. OVERBEEKE C, Tak T, Koenderman L
    The journey of neutropoiesis: how complex landscapes in bone marrow guide continuous neutrophil lineage determination.
    Blood. 2022;139:2285-2293.
    PubMed     Abstract available


  110. WANG M, Dingler FA, Patel KJ
    Genotoxic aldehydes in the hematopoietic system.
    Blood. 2022;139:2119-2129.
    PubMed     Abstract available


    March 2022

  111. Psatha N, Georgakopoulou A, Li C, et al. Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo. Blood. 2021;138(17):1540-1553.
    Blood. 2022;139:2087.
    PubMed    


  112. CAZZOLA M
    RNA missplicing and ring sideroblasts in MDS.
    Blood. 2022;139:1933-1935.
    PubMed    


  113. ALBERT MH, Sirait T, Eikema DJ, Bakunina K, et al
    Hematopoietic stem cell transplantation for adolescents and adults with inborn errors of immunity, an EBMT IEWP study.
    Blood. 2022 Mar 28. pii: 484506. doi: 10.1182/blood.2022015506.
    PubMed     Abstract available



  114. Cutler C, Lee SJ, Arai S, et al. Belumosudil for chronic graft-versus-host disease after 2 or more prior lines of therapy: the ROCKstar study. Blood. 2021;138(22):2278-2289.
    Blood. 2022;139:1772.
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  115. LOU Q, Jiang K, Xu Q, Yuan L, et al
    The RIG-I-NRF2 axis regulates the mesenchymal stromal niche for bone marrow transplantation.
    Blood. 2022 Mar 8. pii: 484313. doi: 10.1182/blood.2021013048.
    PubMed     Abstract available


  116. VERRILLS NM
    PP2A activation targets AML stem cells.
    Blood. 2022;139:1267-1269.
    PubMed    


  117. SUO M, Rommelfanger MK, Chen Y, Amro EM, et al
    Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice.
    Blood. 2022 Mar 1. pii: 484215. doi: 10.1182/blood.2021012197.
    PubMed     Abstract available


    February 2022
  118. LV K, Tong W
    Waking up CML leukemia stem cells for the kill.
    Blood. 2022;139:647-648.
    PubMed    


  119. LANDSPERSKY T, Sacma M, Riviere J, Hecker JS, et al
    Autophagy in mesenchymal progenitors protects mice against bone marrow failure after severe intermittent stress.
    Blood. 2022;139:690-703.
    PubMed     Abstract available


    January 2022
  120. ALBERT MH, Slatter MA, Gennery AR, Gungor T, et al
    Hematopoietic stem cell transplantation for Wiskott-Aldrich syndrome: an EBMT inborn errors working party analysis.
    Blood. 2022 Jan 31. pii: 483752. doi: 10.1182/blood.2021014687.
    PubMed     Abstract available


  121. CHIN DWL, Yoshizato T, Virding Culleton S, Grasso F, et al
    Aged healthy mice acquire clonal hematopoiesis mutations.
    Blood. 2022;139:629-634.
    PubMed    


  122. STONE AP, Nascimento TF, Barrachina MN
    The bone marrow niche from the inside out: how megakaryocytes are shaped by and shape hematopoiesis.
    Blood. 2022;139:483-491.
    PubMed     Abstract available


  123. LAN Y
    Deciphering the continuum of hemogenic endothelium differentiation.
    Blood. 2022;139:308-310.
    PubMed    


  124. FADLULLAH MZH, Neo WH, Lie-A-Ling M, Thambyrajah R, et al
    Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE.
    Blood. 2022;139:343-356.
    PubMed     Abstract available


  125. LOPEZ DE LAPUENTE PORTILLA A, Ekdahl L, Cafaro C, Ali Z, et al
    Genome-wide association study on 13,167 individuals identifies regulators of blood CD34+ cell levels.
    Blood. 2022 Jan 10. pii: 483405. doi: 10.1182/blood.2021013220.
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  126. SAHA A, Hyzy S, Lamothe TL, Hammond KJ, et al
    CD45-targeted antibody-drug-conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation.
    Blood. 2022 Jan 5. pii: 483334. doi: 10.1182/blood.2021012366.
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    December 2021
  127. CAI H, Kondo M, Sandhow L, Xiao P, et al
    Critical Role of Lama4 for Hematopoiesis Regeneration and Acute Myeloid Leukemia Progression.
    Blood. 2021 Dec 27. pii: 483253. doi: 10.1182/blood.2021011510.
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  128. YU Z, Yang W, He X, Chen C, et al
    Endothelial cell-derived angiopoietin-like protein 2 supports hematopoietic stem cell activities in bone marrow niches.
    Blood. 2021 Dec 20. pii: 483187. doi: 10.1182/blood.2021011644.
    PubMed     Abstract available


  129. GANUZA M, Clements WK, McKinney Freeman SL
    Specification of hematopoietic stem cells in mammalian embryos: A rare or frequent event?
    Blood. 2021 Dec 17. pii: 483085. doi: 10.1182/blood.2020009839.
    PubMed     Abstract available


  130. STENGER E
    HSC engraftment in SCD: a MiSCing piece of the puzzle?
    Blood. 2021;138:2451-2452.
    PubMed    


  131. MIYAUCHI M, Ito Y, Nakahara F, Hino T, et al
    Efficient production of human neutrophils from iPSCs that prevent murine lethal infection with immune cell recruitment.
    Blood. 2021;138:2555-2569.
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  132. TANG A, Strat AN, Rahman M, Zhang H, et al
    Murine bone marrow mesenchymal stromal cells have reduced hematopoietic maintenance ability in sickle cell disease.
    Blood. 2021;138:2570-2582.
    PubMed     Abstract available


  133. CHEN Y, Wang D
    STAT5B, the dominant twin, in hematopoietic stem cells.
    Blood. 2021;138:2303-2305.
    PubMed    


  134. QIU Y, Xu M, Huang S
    Long noncoding RNAs: emerging regulators of normal and malignant hematopoiesis.
    Blood. 2021;138:2327-2336.
    PubMed     Abstract available


  135. WEEKS LD, Marinac CR, Redd RA, Abel GA, et al
    Age-related Diseases of Inflammation in Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia.
    Blood. 2021 Dec 7. pii: 482919. doi: 10.1182/blood.2021014418.
    PubMed    


  136. CHEN C, Yu W, Alikarami F, Qiu Q, et al
    Single-cell multiomics reveals increased plasticity, resistant populations and stem-cell-like blasts in KMT2A-rearranged leukemia.
    Blood. 2021 Dec 5. pii: 482898. doi: 10.1182/blood.2021013442.
    PubMed     Abstract available


  137. MOSCA M, Hermange G, Tisserand A, Noble R, et al
    Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNalpha in myeloproliferative neoplasms.
    Blood. 2021;138:2231-2243.
    PubMed     Abstract available


    November 2021
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    Dopamine motivates stem cells for reward.
    Blood. 2021;138:2012-2014.
    PubMed    


  139. LIU Y, Chen Q, Jeong HW, Han D, et al
    Dopamine signaling regulates hematopoietic stem and progenitor cell function.
    Blood. 2021;138:2051-2065.
    PubMed     Abstract available


  140. LADEL L, Jamieson CHM
    Upping the antizyme: AZIN1 directs stem cell fate.
    Blood. 2021;138:1910-1911.
    PubMed    


  141. ZHANG H, Wang S, Liu D, Gao C, et al
    EpoR-tdTomato-Cre mice enable identification of EpoR expression in subsets of tissue macrophages and hematopoietic cells.
    Blood. 2021;138:1986-1997.
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  142. BRAND M
    Epigenetic plasticity of erythroid progenitors.
    Blood. 2021;138:1646-1648.
    PubMed    


  143. FENG Y, Feng W
    Numerous ring sideroblasts in chronic neutrophilic leukemia.
    Blood. 2021;138:1783.
    PubMed    


  144. FUCHS EJ, McCurdy SR, Solomon SR, Wang T, et al
    HLA Informs Risk Predictions after Haploidentical Stem Cell Transplantation with Post-transplantation Cyclophosphamide.
    Blood. 2021 Nov 1. pii: 477735. doi: 10.1182/blood.2021013443.
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  145. YANG Y, Kueh AJ, Grant Z, Abeysekera W, et al
    The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal.
    Blood. 2021 Nov 1. pii: 477737. doi: 10.1182/blood.2021013954.
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    October 2021
  146. SCHNOEDER TM, Schwarzer A, Jayavelu AK, Hsu CJ, et al
    PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
    Blood. 2021 Oct 25. pii: S0006-4971(21)01783-3. doi: 10.1182/blood.2021012778.
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  147. DOCAMPO MD, Burgos da Silva M, Lazrak A, Nichols KB, et al
    Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease.
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  148. FISHMAN H, Madiwale S, Geron I, Bari V, et al
    ETV6-NCOA2 fusion induces T/Myeloid mixed-phenotype leukemia by transformation of non-thymic hematopoietic progenitors.
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    September 2021
  149. TERMINI CM, Pang A, Li M, Fang T, et al
    Syndecan-2 expression enriches for hematopoietic stem cells and regulates stem cell repopulating capacity.
    Blood. 2021 Sep 10. pii: 476854. doi: 10.1182/blood.2020010447.
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  150. DAVIS AG, Johnson DT, Zheng D, Wang R, et al
    Alternative polyadenylation dysregulation contributes to the differentiation block of acute myeloid leukemia.
    Blood. 2021 Sep 5. pii: 476791. doi: 10.1182/blood.2020005693.
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    August 2021
  151. COCHRAN T, Li W
    Frequent internuclear bridging in a Fanconi anemia patient with FANCG mutation.
    Blood. 2021;138:738.
    PubMed    


  152. JANN JC, Tothova Z
    Cohesin mutations in myeloid malignancies.
    Blood. 2021;138:649-661.
    PubMed     Abstract available


    July 2021
  153. GURNARI C, Pagliuca S, Durkin L, Terkawi L, et al
    Vacuolization of hematopoietic precursors: an enigma with multiple etiologies.
    Blood. 2021;137:3685-3689.
    PubMed    


    June 2021
  154. MIKDAR M, Gonzalez-Menendez P, Cai X, Zhang Y, et al
    The equilibrative nucleoside transporter ENT1 is critical for nucleotide homeostasis and optimal erythropoiesis.
    Blood. 2021;137:3548-3562.
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  155. SOMMERKAMP P, Romero-Mulero MC, Narr A, Ladel L, et al
    Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells.
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  156. PASTORET C, Desmots F, Drillet G, Le Gallou S, et al
    Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells.
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  157. SCHURCH CM, Caraccio C, Nolte MA
    Diversity, localization, and (patho)physiology of mature lymphocyte populations in the bone marrow.
    Blood. 2021;137:3015-3026.
    PubMed     Abstract available


  158. SOMASUNDARAM R, Jensen CT, Tingvall-Gustafsson J, Ahsberg J, et al
    EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene.
    Blood. 2021;137:3037-3049.
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    May 2021
  159. LIU H
    Basophilic myeloblasts: a clue for CML blast phase.
    Blood. 2021;137:2852.
    PubMed    


  160. BORELLA G, Da Ros A, Borile G, Porcu E, et al
    Targeting mesenchymal stromal cells plasticity to reroute acute myeloid leukemia course.
    Blood. 2021 May 19. pii: 475978. doi: 10.1182/blood.2020009845.
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  161. TAKEDA MR, Gurbuxani S
    bcr3 PML-RARA: short fusion, small blasts!
    Blood. 2021;137:2708.
    PubMed    


  162. SURAPALLY S, Tenen DG, Pulikkan JA
    Emerging therapies for inv(16) AML.
    Blood. 2021;137:2579-2584.
    PubMed     Abstract available


  163. DE RAVIN SS, Brault J, Meis RJ, Liu S, et al
    Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells.
    Blood. 2021;137:2598-2608.
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  164. ESTEVEZ B, Borst S, Jarocha D, Sudunagunta V, et al
    RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells.
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  165. SILVA AP, Almeida ARM, Cachucho A, Neto JL, et al
    Overexpression of wild type IL-7Ralpha promotes T-cell acute lymphoblastic leukemia/lymphoma.
    Blood. 2021 May 10. pii: 475938. doi: 10.1182/blood.2019000553.
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  166. ANAND P, Guillaumet-Adkins A, Dimitrova V, Yun H, et al
    Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL.
    Blood. 2021;137:2463-2480.
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    March 2021
  167. NIU X, Rothe K, Chen M, Grasedieck S, et al
    Targeting AXL Kinase Sensitizes Leukemic Stem and Progenitor Cells to Venetoclax Treatment in Acute Myeloid Leukemia.
    Blood. 2021 Mar 30. pii: 475648. doi: 10.1182/blood.2020007651.
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    January 2021
  168. MU A, Hira A, Niwa A, Osawa M, et al
    Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
    Blood. 2021 Jan 12. pii: 474923. doi: 10.1182/blood.2020009111.
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    September 2020
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    Conditional expression of HGAL leads to the development of diffuse large B-cell lymphoma in mice.
    Blood. 2020 Sep 6. pii: 464123. doi: 10.1182/blood.2020004996.
    PubMed     Abstract available


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