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Prostate Cancer

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January 2012
1. LESSARD L , Labbe DP, Deblois G, Begin LR, et al
   PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer.
   Cancer Res. 2012.
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2. CLEGG NJ , Wongvipat J, Tran C, Ouk S, et al
   ARN-509: a novel anti-androgen for prostate cancer treatment.
   Cancer Res. 2012.
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   December 2011
3. FRIEDLANDER TW , Roy R, Tomlins SA, Ngo VT, et al
   Common Structural and Epigenetic Changes in the Genome of Castration Resistant Prostate Cancer.
   Cancer Res. 2011.
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   November 2011
4. 
   Correction: Definition of a FoxA1 Cistrome That Is Crucial for G1 to S-Phase Cell-Cycle Transit in Castration-Resistant Prostate Cancer.
   Cancer Res. 2011.
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5. ROWLANDS MA , Holly JM, Gunnell D, Donovan JL, et al
   Circulating insulin-like growth factors (IGFs) and IGF binding proteins (IGFBPs) in PSA-detected prostate cancer: the large case control study ProtecT.
   Cancer Res. 2011.
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6. SONG JH , Kraft AS
   Pim kinase inhibitors sensitize prostate cancer cells to apoptosis triggered by Bcl-2 family inhibitor ABT-737.
   Cancer Res. 2011.
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   October 2011
7. LI L , Ren C, Yang G, Fattah EA, et al
   GLIPR1 suppresses prostate cancer development by targeted oncoprotein destruction.
   Cancer Res. 2011.
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8. WANG Q , Bailey CG, Ng C, Tiffen J, et al
   Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression.
   Cancer Res. 2011.
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9. WARD Y , Lake R, Yin JJ, Heger CD, et al
   LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells.
   Cancer Res. 2011.
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   September 2011
10. JIANG ZK , Sato M, Wei LH, Kao C, et al
    Androgen-Independent Molecular Imaging Vectors to Detect Castration-Resistant and Metastatic Prostate Cancer.
    Cancer Res. 2011.
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11. PITTONI P , Tripodo C, Piconese S, Mauri G, et al
    Mast cell targeting hampers prostate adenocarcinoma development but promotes the occurrence of highly malignant neuroendocrine cancers.
    Cancer Res. 2011;71:5987-97.
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12. VALERIE NC , Casarez EV, Dasilva JO, Dunlap-Brown M, et al
    Inhibition of neurotensin receptor 1 selectively sensitizes prostate cancer to ionizing radiation.
    Cancer Res. 2011.
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13. ZHANG C , Wang L, Wu D, Chen H, et al
    Definition of a FoxA1 Cistrome that is Crucial for G1-S Phase Cell- Cycle Transit in Castration-Resistant Prostate Cancer.
    Cancer Res. 2011.
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    August 2011
14. SMITH HA , Cronk RJ, Lang JM, McNeel DG, et al
    Expression and Immunotherapeutic Targeting of the SSX Family of Cancer-Testis Antigens in Prostate Cancer.
    Cancer Res. 2011.
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15. CAI C , Chen S, Ng P, Bubley GJ, et al
    Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration Resistant Prostate Cancer and is Upregulated by Treatment with CYP17A1 Inhibitors.
    Cancer Res. 2011.
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16. MANI RS , Iyer MK, Cao Q, Brenner JC, et al
    TMPRSS2-ERG-mediated feed-forward regulation of wild-type ERG in human prostate cancers.
    Cancer Res. 2011;71:5387-92.
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17. LEE YC , Cheng CJ, Bilen MA, Lu JF, et al
    BMP4 promotes prostate tumor growth in bone through osteogenesis.
    Cancer Res. 2011;71:5194-203.
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18. ROUNTREE RB , Mandl SJ, Nachtwey JM, Dalpozzo K, et al
    Exosome targeting of tumor antigens expressed by cancer vaccines can improve antigen immunogenicity and therapeutic efficacy.
    Cancer Res. 2011;71:5235-44.
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19. PALASKAS N , Larson SM, Schultz N, Komisopoulou E, et al
    18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers.
    Cancer Res. 2011;71:5164-74.
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    July 2011
20. DARSHAN MS , Loftus MS, Thadani-Mulero M, Levy BP, et al
    Taxane-Induced Blockade to Nuclear Accumulation of the Androgen Receptor Predicts Clinical Responses in Metastatic Prostate Cancer.
    Cancer Res. 2011.
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21. FUCIKOVA J , Kralikova P, Fialova A, Brtnicky T, et al
    Human tumor cells killed by anthracyclines induce a tumor-specific immune response.
    Cancer Res. 2011;71:4821-33.
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22. LUBIK AA , Gunter JH, Hendy SC, Locke JA, et al
    Insulin increases de novo steroidogenesis in prostate cancer cells.
    Cancer Res. 2011.
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23. LAMOUREUX F , Thomas C, Yin MJ, Kuruma H, et al
    Clusterin Inhibition using OGX-011 Synergistically Enhances Hsp90 Inhibitor Activity by Suppressing the Heat Shock Response in Castrate Resistant Prostate Cancer.
    Cancer Res. 2011.
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24. BEN SAHRA I , Regazzetti C, Robert G, Laurent K, et al
    Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.
    Cancer Res. 2011;71:4366-72.
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    June 2011
25. MATHIEU J , Zhang Z, Zhou W, Wang AJ, et al
    HIF Induces Human Embryonic Stem Cell Markers in Cancer Cells.
    Cancer Res. 2011.
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26. MEHTA H , Gao Q, Galet C, Paharkova V, et al
    IGFBP-3 is a Metastasis Suppression Gene in Prostate Cancer.
    Cancer Res. 2011.
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27. CINAR B , Collak FK, Lopez D, Akgul S, et al
    MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling.
    Cancer Res. 2011;71:4303-13.
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28. 
    Correction: Hsp27 Promotes Insulin-Like Growth Factor-I Survival Signaling in Prostate Cancer via p90Rsk-Dependent Phosphorylation and Inactivation of BAD.
    Cancer Res. 2011.
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    May 2011
29. RICHMAN EL , Kenfield SA, Stampfer MJ, Paciorek A, et al
    Physical Activity after Diagnosis and Risk of Prostate Cancer Progression: Data from the Cancer of the Prostate Strategic Urologic Research Endeavor.
    Cancer Res. 2011.
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30. WANG H , Zhang C, Rorick A, Wu D, et al
    CCI-779 Inhibits Cell-Cycle G2/M Progression and Invasion of Castration-Resistant Prostate Cancer via Attenuation of UBE2C Transcription and mRNA Stability.
    Cancer Res. 2011.
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31. ROMERO D , O'Neill C, Terzic A, Contois L, et al
    Endoglin regulates cancer-stromal cell interactions in prostate tumors.
    Cancer Res. 2011;71:3482-93.
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32. KISKOWSKI MA , Jackson RS 2nd, Banerjee J, Li X, et al
    Role for stromal heterogeneity in prostate tumorigenesis.
    Cancer Res. 2011;71:3459-70.
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33. CATALONA WJ , Bailey-Wilson JE, Camp NJ, Chanock SJ, et al
    National Cancer Institute Prostate Cancer Genetics Workshop.
    Cancer Res. 2011.
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34. BENITEZ A , Yates TJ, Lopez LE, Cerwinka WH, et al
    TARGETING HYALURONIDASE FOR CANCER THERAPY: ANTITUMOR ACTIVITY OF SULFATED HYALURONIC ACID IN PROSTATE CANCER CELLS.
    Cancer Res. 2011.
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35. ILIOPOULOS D , Hirsch HA, Struhl K
    Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types.
    Cancer Res. 2011;71:3196-201.
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    April 2011
36. ZHANG H , Pan Y, Zheng L, Choe C, et al
    FOXO1 Inhibits Runx2 Transcriptional Activity and Prostate Cancer Cell Migration and Invasion.
    Cancer Res. 2011.
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37. ELLWOOD-YEN K , Keilhack H, Kunii K, Dolinski B, et al
    PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models.
    Cancer Res. 2011;71:3052-65.
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38. JIA Z , Wang Y, Sawyers A, Yao H, et al
    Diagnosis of Prostate Cancer Using Differentially Expressed Genes in Stroma.
    Cancer Res. 2011;71:2476-2487.
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39. JOSSON S , Nomura T, Lin JT, Huang WC, et al
    beta2-microglobulin induces epithelial to mesenchymal transition and confers cancer lethality and bone metastasis in human cancer cells.
    Cancer Res. 2011;71:2600-10.
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40. LAMB LE , Zarif JC, Miranti CK
    The androgen receptor induces integrin alpha6beta1 to promote prostate tumor cell survival via NF-kappaB and Bcl-xL Independently of PI3K signaling.
    Cancer Res. 2011;71:2739-49.
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    March 2011
41. HAFEEZ BB , Zhong W, Weichert J, Dreckschmidt NE, et al
    Genetic Ablation of PKC Epsilon Inhibits Prostate Cancer Development and Metastasis in Transgenic Mouse Model of Prostate Adenocarcinoma.
    Cancer Res. 2011;71:2318-27.
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42. LI W , Wang L, Katoh H, Liu R, et al
    Identification of a tumor suppressor relay between the FOXP3 and the Hippo pathways in breast and prostate cancers.
    Cancer Res. 2011;71:2162-71.
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43. SINGH RK , Lokeshwar BL
    The IL-8 regulated Chemokine Receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth.
    Cancer Res. 2011.
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44. ZHANG D , He D, Xue Y, Wang R, et al
    PrLZ Protects Prostate Cancer Cells from Apoptosis Induced by Androgen Deprivation via the Activation of Stat3/Bcl-2 Pathway.
    Cancer Res. 2011.
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45. CIAMPA J , Yeager M, Amundadottir L, Jacobs K, et al
    Large Scale Exploration of Gene-Gene Interactions in Prostate Cancer Using a Multi-stage Genome-wide Association Study.
    Cancer Res. 2011.
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46. MUTHANA M , Giannoudis A, Scott SD, Fang HY, et al
    Use of macrophages to target therapeutic adenovirus to human prostate tumors.
    Cancer Res. 2011;71:1805-15.
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    February 2011
47. RIDDELL JR , Bshara W, Moser MT, Spernyak JA, et al
    Peroxiredoxin 1 Controls Prostate Cancer Growth through Toll-Like Receptor 4-Dependent Regulation of Tumor Vasculature.
    Cancer Res. 2011.
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48. OSTLING P , Leivonen SK, Aakula A, Kohonen P, et al
    Systematic Analysis of MicroRNAs Targeting the Androgen Receptor in Prostate Cancer Cells.
    Cancer Res. 2011.
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49. HEEMERS HV , Schmidt LJ, Sun Z, Regan KM, et al
    Identification of a Clinically Relevant Androgen-Dependent Gene Signature in Prostate Cancer.
    Cancer Res. 2011.
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50. FRANCO OE , Jiang M, Strand DW, Peacock J, et al
    Altered TGF-beta signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis.
    Cancer Res. 2011;71:1272-81.
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51. SADAR MD
    Small molecule inhibitors targeting the "achilles' heel" of androgen receptor activity.
    Cancer Res. 2011;71:1208-13.
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52. WANG J , Cai Y, Shao LJ, Siddiqui J, et al
    Activation of NF-{kappa}B by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4.
    Cancer Res. 2011;71:1325-33.
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53. MOHLER JL , Titus MA, Bai S, Kennerley BJ, et al
    Activation of the Androgen Receptor by Intratumoral Bioconversion of Androstanediol to Dihydrotestosterone in Prostate Cancer.
    Cancer Res. 2011.
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    January 2011
54. LI Y , Alsagabi M, Fan D, Bova GS, et al
    Intragenic rearrangement and altered RNA splicing of the androgen receptor in a cell-based model of prostate cancer progression.
    Cancer Res. 2011.
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55. WILD D , Frischknecht M, Zhang H, Morgenstern A, et al
    Alpha- versus Beta-Particle Radiopeptide Therapy in a Human Prostate Cancer Model (213Bi-DOTA-PESIN and 213Bi-AMBA versus177Lu-DOTA-PESIN).
    Cancer Res. 2011.
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56. HODGSON MC , Shao LJ, Frolov A, Li R, et al
    Decreased Expression and Androgen Regulation of the Tumor Suppressor Gene INPP4B in Prostate Cancer.
    Cancer Res. 2011.
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57. MA S , Chan YP, Kwan PS, Lee TK, et al
    microRNA-616 Induces Androgen-Independent Growth of Prostate Cancer Cells by Suppressing Expression of Tissue Factor Pathway Inhibitor TFPI-2.
    Cancer Res. 2011.
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58. SUN D , Lee YS, Malhotra A, Kim HK, et al
    miR-99 family of microRNAs suppresses the expression of prostate specific antigen and prostate cancer cell proliferation.
    Cancer Res. 2011.
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59. LI CM , Wang Z, Lu Y, Ahn S, et al
    Biological activity of 4-substituted methoxybenzoyl-aryl-thiazole: an active microtubule inhibitor.
    Cancer Res. 2011;71:216-24.
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    December 2010
60. POWELL MJ , Casimiro MC, Cordon-Cardo C, He X, et al
    Disruption of a Sirt1 Dependent Autophagy Checkpoint in the Prostate Results in Prostatic Intraepithelial Neoplasia Lesion Formation.
    Cancer Res. 2010.
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61. BROOKE GN , Culley RL, Dart DA, Mann DJ, et al
    FUS/TLS is a novel mediator of androgen-dependent cell cycle progression and prostate cancer growth.
    Cancer Res. 2010.
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62. WANG J , Place RF, Huang V, Wang X, et al
    Prognostic Value and Function of KLF4 in Prostate Cancer: RNAa and Vector-Mediated Overexpression Identify KLF4 as an Inhibitor of Tumor Cell Growth and Migration.
    Cancer Res. 2010;70:10182-91.
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63. CAI H , Babic I, Wei X, Huang J, et al
    Invasive prostate carcinoma driven by c-Src and androgen receptor synergy.
    Cancer Res. 2010.
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64. FISHER JW , Sarkar S, Buchanan CF, Szot CS, et al
    Photothermal response of human and murine cancer cells to multiwalled carbon nanotubes after laser irradiation.
    Cancer Res. 2010;70:9855-64.
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65. ADDADI Y , Moskovits N, Granot D, Lozano G, et al
    p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner.
    Cancer Res. 2010;70:9650-8.
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66. BASTUS NC , Boyd LK, Mao X, Stankiewicz E, et al
    Androgen-induced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells.
    Cancer Res. 2010;70:9544-8.
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67. WU P , Kudrolli TA, Chowdhury WH, Liu MM, et al
    Adenovirus targeting to prostate-specific membrane antigen through virus-displayed, semirandom peptide library screening.
    Cancer Res. 2010;70:9549-53.
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    November 2010
68. USTACH CV , Huang W, Conley-Lacomb MK, Lin CY, et al
    A Novel Signaling Axis of Matriptase/PDGF-D/{beta}-PDGFR in Human Prostate Cancer.
    Cancer Res. 2010.
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69. HALL CL , Zhang H, Baile S, Ljungman M, et al
    p21CIP-1/WAF-1 Induction Is Required to Inhibit Prostate Cancer Growth Elicited by Deficient Expression of the Wnt Inhibitor Dickkopf-1.
    Cancer Res. 2010.
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70. MOLTZAHN F , Olshen AB, Baehner L, Peek AS, et al
    Microfluidic based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in sera of prostate cancer patients.
    Cancer Res. 2010.
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71. FRIGO DE , Howe MK, Wittmann BM, Brunner AM, et al
    CaM kinase kinase {beta}-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells.
    Cancer Res. 2010.
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72. PLOUSSARD G , Terry S, Maille P, Allory Y, et al
    Class III beta-tubulin expression predicts prostate tumor aggressiveness and patient response to docetaxel-based chemotherapy.
    Cancer Res. 2010;70:9253-64.
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73. SU Y , Meador JA, Calaf GM, De-Santis LP, et al
    Human RecQL4 helicase plays critical roles in prostate carcinogenesis.
    Cancer Res. 2010;70:9207-17.
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74. WANG WX , Kyprianou N, Wang X, Nelson PT, et al
    Dysregulation of the mitogen granulin in human cancer through the miR-15/107 microRNA gene group.
    Cancer Res. 2010;70:9137-42.
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75. WAHDAN-ALASWAD RS , Song K, Krebs TL, Shola DT, et al
    Insulin-Like Growth Factor I Suppresses Bone Morphogenetic Protein Signaling in Prostate Cancer Cells by Activating mTOR Signaling.
    Cancer Res. 2010.
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76. KARNES RJ , Cheville JC, Ida CM, Sebo TJ, et al
    The Ability of Biomarkers to Predict Systemic Progression in Men with High-Risk Prostate Cancer Treated Surgically Is Dependent on ERG Status.
    Cancer Res. 2010.
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77. REYES-REYES EM , Teng Y, Bates PJ
    A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism.
    Cancer Res. 2010;70:8617-29.
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78. SHIH YP , Liao YC, Lin Y, Lo SH, et al
    DLC1 negatively regulates angiogenesis in a paracrine fashion.
    Cancer Res. 2010;70:8270-5.
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    October 2010
79. KOUTROS S , Beane Freeman LE, Berndt SI, Andreotti G, et al
    Pesticide Use Modifies the Association Between Genetic Variants on Chromosome 8q24 and Prostate Cancer.
    Cancer Res. 2010.
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80. ALOIA AL , Sfanos KS, Isaacs WB, Zheng Q, et al
    XMRV: A New Virus in Prostate Cancer?
    Cancer Res. 2010.
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81. YIN JJ , Zhang L, Munasinghe J, Linnoila RI, et al
    Cediranib/AZD2171 Inhibits Bone and Brain Metastasis in a Preclinical Model of Advanced Prostate Cancer.
    Cancer Res. 2010.
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82. PCHEJETSKI D , Bohler T, Brizuela L, Sauer L, et al
    FTY720 (Fingolimod) Sensitizes Prostate Cancer Cells to Radiotherapy by Inhibition of Sphingosine Kinase-1.
    Cancer Res. 2010.
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83. MOSTAGHEL E , Nelson PS, Nelson C, Montgomery RB, et al
    Intraprostatic steroidogenic enzymes - letter.
    Cancer Res. 2010;70:8247-9.
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84. DU C , Zhang C, Hassan S, Biswas MH, et al
    Protein kinase D1 suppresses epithelial-to-mesenchymal transition through phosphorylation of snail.
    Cancer Res. 2010;70:7810-9.
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85. SUGIYAMA N , Varjosalo M, Meller P, Lohi J, et al
    Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation.
    Cancer Res. 2010;70:7851-61.
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86. RYSMAN E , Brusselmans K, Scheys K, Timmermans L, et al
    De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation.
    Cancer Res. 2010;70:8117-26.
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87. YANG CH , Yue J, Fan M, Pfeffer LM, et al
    IFN induces miR-21 through a signal transducer and activator of transcription 3-dependent pathway as a suppressive negative feedback on IFN-induced apoptosis.
    Cancer Res. 2010;70:8108-16.
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88. DONG Y , Bey EA, Li LS, Kabbani W, et al
    Prostate Cancer Radiosensitization through Poly(ADP-Ribose) Polymerase-1 Hyperactivation.
    Cancer Res. 2010.
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89. KLADNEY RD , Cardiff RD, Kwiatkowski DJ, Chiang GG, et al
    Tuberous Sclerosis Complex 1: An Epithelial Tumor Suppressor Essential to Prevent Spontaneous Prostate Cancer in Aged Mice.
    Cancer Res. 2010.
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90. DAFNI H , Larson PE, Hu S, Yoshihara HA, et al
    Hyperpolarized 13C spectroscopic imaging informs on hypoxia-inducible factor-1 and myc activity downstream of platelet-derived growth factor receptor.
    Cancer Res. 2010;70:7400-10.
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    September 2010
91. YANG D , Kedei N, Li L, Tao J, et al
    RasGRP3 Contributes to Formation and Maintenance of the Prostate Cancer Phenotype.
    Cancer Res. 2010.
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92. XU D , McKee CM, Cao Y, Ding Y, et al
    Matrix metalloproteinase-9 regulates tumor cell invasion through cleavage of protease nexin-1.
    Cancer Res. 2010;70:6988-98.
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    August 2010
93. LIAO CP , Adisetiyo H, Liang M, Roy-Burman P, et al
    Cancer-Associated Fibroblasts Enhance the Gland-Forming Capability of Prostate Cancer Stem Cells.
    Cancer Res. 2010.
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94. ZHU M , Horbinski C, Garzotto M, Qian DZ, et al
    Tubulin-Targeting Chemtherapy Impairs Androgen Receptor Activity in Prostate Cancer.
    Cancer Res. 2010.
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