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  Pulmonary Hypertension

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Articles published in Circulation

Retrieve available abstracts of 65 articles:
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Single Articles


    April 2024
  1. SHEN H, Gao Y, Ge D, Tan M, et al
    BRCC3 Regulation of ALK2 in Vascular Smooth Muscle Cells: Implication in Pulmonary Hypertension.
    Circulation. 2024 Apr 1. doi: 10.1161/CIRCULATIONAHA.123.066430.
    PubMed     Abstract available


    March 2024
  2. AGGARWAL V, Giri J, Visovatti SH, Mahmud E, et al
    Status and Future Directions for Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Disease With and Without Pulmonary Hypertension: A Scientific Statement From the American Heart Association.
    Circulation. 2024 Mar 7. doi: 10.1161/CIR.0000000000001197.
    PubMed     Abstract available


    February 2024
  3. LUO Y, Qi X, Zhang Z, Zhang J, et al
    Inactivation of Malic Enzyme 1 in Endothelial Cells Alleviates Pulmonary Hypertension.
    Circulation. 2024 Feb 5. doi: 10.1161/CIRCULATIONAHA.123.067579.
    PubMed     Abstract available


    January 2024
  4. BIAN JS, Chen J, Zhang J, Tan J, et al
    ErbB3 Governs Endothelial Dysfunction in Hypoxia-Induced Pulmonary Hypertension.
    Circulation. 2024 Jan 12. doi: 10.1161/CIRCULATIONAHA.123.067005.
    PubMed     Abstract available


    November 2023
  5. WALTERS R, Vasilaki E, Wilkins MR, Zhao L, et al
    Response by Walters et al to Letter Regarding Article, "SOX17 Enhancer Variants Disrupt Transcription Factor Binding and Enhancer Inactivity Drives Pulmonary Hypertension".
    Circulation. 2023;148:1825-1826.
    PubMed    


  6. LI G, Chen H, Ren C
    Letter by Li et al Regarding Article, "SOX17 Enhancer Variants Disrupt Transcription Factor Binding and Enhancer Inactivity Drives Pulmonary Hypertension".
    Circulation. 2023;148:1823-1824.
    PubMed    


  7. HOSOKAWA K, Watanabe H, Taniguchi Y, Ikeda N, et al
    A Multicenter, Single-Blind, Randomized, Warfarin-Controlled Trial of Edoxaban in Patients With Chronic Thromboembolic Pulmonary Hypertension: KABUKI Trial.
    Circulation. 2023 Nov 13. doi: 10.1161/CIRCULATIONAHA.123.067528.
    PubMed    


    September 2023
  8. KUEHN BM
    Experimental Drug, Combination Pill Show Promise for Treating Pulmonary Hypertension.
    Circulation. 2023;148:852-854.
    PubMed    


    July 2023

  9. Correction to: Heteroplasmy of Wild-Type Mitochondrial DNA Variants in Mice Causes Metabolic Heart Disease With Pulmonary Hypertension and Frailty.
    Circulation. 2023;148:e2.
    PubMed    


    May 2023
  10. JANI V, Aslam MI, Fenwick AJ, Ma W, et al
    Right Ventricular Sarcomere Contractile Depression and the Role of Thick Filament Activation in Human Heart Failure With Pulmonary Hypertension.
    Circulation. 2023 May 17. doi: 10.1161/CIRCULATIONAHA.123.064717.
    PubMed     Abstract available



  11. Correction to: Gremlin Plays a Key Role in the Pathogenesis of Pulmonary Hypertension.
    Circulation. 2023;147:e718.
    PubMed    


    April 2023
  12. GUIGNABERT C, Savale L, Boucly A, Thuillet R, et al
    Serum and Pulmonary Expression Profiles of the Activin Signaling System in Pulmonary Arterial Hypertension.
    Circulation. 2023 Apr 25. doi: 10.1161/CIRCULATIONAHA.122.061501.
    PubMed     Abstract available


  13. WALTERS R, Vasilaki E, Aman J, Chen CN, et al
    SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension.
    Circulation. 2023 Apr 17. doi: 10.1161/CIRCULATIONAHA.122.061940.
    PubMed     Abstract available


    March 2023
  14. RAJAGOPAL S, Ruetzler K, Ghadimi K, Horn EM, et al
    Evaluation and Management of Pulmonary Hypertension in Noncardiac Surgery: A Scientific Statement From the American Heart Association.
    Circulation. 2023 Mar 16. doi: 10.1161/CIR.0000000000001136.
    PubMed     Abstract available


    February 2023
  15. CHIN KM, Santiago-Munoz P
    Pregnancy and Congenital Heart Disease-Associated Pulmonary Hypertension: Are Outcomes Improving?
    Circulation. 2023;147:562-564.
    PubMed    


  16. ZHANG Q, Zhu F, Shi G, Hu C, et al
    Maternal Outcomes Among Pregnant Women With Congenital Heart Disease-Associated Pulmonary Hypertension.
    Circulation. 2023;147:549-561.
    PubMed     Abstract available


    December 2022
  17. BORN E, Lipskaia L, Breau M, Houssaini A, et al
    Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression.
    Circulation. 2022 Dec 14. doi: 10.1161/CIRCULATIONAHA.122.058794.
    PubMed     Abstract available


    November 2022
  18. ZHOU W, Liu K, Zeng L, He J, et al
    Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension.
    Circulation. 2022 Nov 17. doi: 10.1161/CIRCULATIONAHA.122.061900.
    PubMed     Abstract available


  19. JHA AK
    Letter by Jha Regarding Article, "Latent Pulmonary Vascular Disease and Therapeutic Atrial Shunt".
    Circulation. 2022;146:e242-e243.
    PubMed    


  20. BORLAUG BA, Shah SJ
    Response by Borlaug and Shah Regarding Article, "Latent Pulmonary Vascular Disease and Therapeutic Atrial Shunt".
    Circulation. 2022;146:e244-e245.
    PubMed    


    September 2022
  21. ZHONG Y, Yu PB
    Decoding the Link Between Inflammation and Pulmonary Arterial Hypertension.
    Circulation. 2022;146:1023-1025.
    PubMed    



  22. Correction to: Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia.
    Circulation. 2022;146:e168.
    PubMed    


    August 2022
  23. BRUSCA SB, Elinoff JM, Zou Y, Jang MK, et al
    Plasma Cell-Free DNA Predicts Survival and Maps Specific Sources of Injury in Pulmonary Arterial Hypertension.
    Circulation. 2022 Aug 25:101161CIRCULATIONAHA121056719.
    PubMed     Abstract available


  24. YAKU A, Inagaki T, Asano R, Okazawa M, et al
    Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages.
    Circulation. 2022 Aug 23:101161CIRCULATIONAHA122059435.
    PubMed     Abstract available


  25. RUFFENACH G, Medzikovic L, Aryan L, Li M, et al
    HNRNPA2B1: RNA-Binding Protein That Orchestrates Smooth Muscle Cell Phenotype in Pulmonary Arterial Hypertension.
    Circulation. 2022 Aug 22:101161CIRCULATIONAHA122059591.
    PubMed     Abstract available


  26. STEFFES LC, Cheng P, Quertermous T, Kumar ME, et al
    von Willebrand Factor Is Produced Exclusively by Endothelium, Not Neointima, in Occlusive Vascular Lesions in Both Pulmonary Hypertension and Atherosclerosis.
    Circulation. 2022;146:429-431.
    PubMed    


  27. JIN Q, Guan L, Zhou D
    Letter by Jin et al Regarding Article, "SPARC, A Novel Regulator of Vascular Cell Function in Pulmonary Hypertension".
    Circulation. 2022;146:e14-e15.
    PubMed    


  28. VEITH C, Ghofrani HA, Weissmann N
    Response by Veith et al to Letter Regarding Article, "SPARC, A Novel Regulator of Vascular Cell Function in Pulmonary Hypertension".
    Circulation. 2022;146:e16-e17.
    PubMed    


    July 2022
  29. BRITTAIN EL, Thenappan T, Huston JH, Agrawal V, et al
    Elucidating the Clinical Implications and Pathophysiology of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction: A Call to Action: A Science Advisory From the American Heart Association.
    Circulation. 2022 Jul 11:101161CIR0000000000001079.
    PubMed     Abstract available


  30. TREMBLAY E, Gosselin C, Mai V, Lajoie AC, et al
    Assessment of Clinical Worsening End Points as a Surrogate for Mortality in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Circulation. 2022 Jul 8:101161CIRCULATIONAHA121058635.
    PubMed     Abstract available


    March 2022
  31. STEWART RH, Cox CS Jr, Allen SJ, Laine GA, et al
    Myocardial Edema Provides a Link Between Pulmonary Arterial Hypertension and Pericardial Effusion.
    Circulation. 2022;145:793-795.
    PubMed    


  32. LECHUGA-VIECO AV, Latorre-Pellicer A, Calvo E, Torroja C, et al
    Heteroplasmy of Wild Type Mitochondrial DNA Variants in Mice Causes Metabolic Heart Disease With Pulmonary Hypertension and Frailty.
    Circulation. 2022 Mar 3. doi: 10.1161/CIRCULATIONAHA.121.056286.
    PubMed     Abstract available


    February 2022
  33. VEITH C, Varturk-Ozcan I, Wujak M, Hadzic S, et al
    Secreted Protein Acidic and Rich in Cysteine, a Novel Regulator of Vascular Cell Function in Pulmonary Hypertension.
    Circulation. 2022 Feb 17. doi: 10.1161/CIRCULATIONAHA.121.057001.
    PubMed     Abstract available


    November 2021
  34. NAEIJE R
    Letter by Naeije Regarding Article, "Oxygen Pathway Limitations in Patients With Chronic Thromboembolic Pulmonary Hypertension".
    Circulation. 2021;144:e328-e329.
    PubMed    


  35. HOWDEN EJ, Ruiz-Carmona S, La Gerche A, Delcroix M, et al
    Response by Howden et al to Letter Regarding Article, "Oxygen Pathway Limitations in Patients With Chronic Thromboembolic Pulmonary Hypertension".
    Circulation. 2021;144:e330-e331.
    PubMed    


    October 2021
  36. FUJIWARA T, Takeda N, Hara H, Ishii S, et al
    Three-Dimensional Visualization of Hypoxia-Induced Pulmonary Vascular Remodeling in Mice.
    Circulation. 2021;144:1452-1455.
    PubMed    


    August 2021
  37. LEOPOLD JA
    Nanoparticle-Facilitated Gene Delivery in Congenital Pulmonary Vascular Disease: Roadmap for Other Forms of Pulmonary Hypertension.
    Circulation. 2021;144:556-558.
    PubMed    


    July 2021
  38. QI H, Liu H, Pullamsetti SS, Gunther S, et al
    Epigenetic Regulation by Suv4-20h1 in Cardiopulmonary Progenitor Cells is Required to Prevent Pulmonary Hypertension and COPD.
    Circulation. 2021 Jul 12. doi: 10.1161/CIRCULATIONAHA.120.051680.
    PubMed     Abstract available


    June 2021
  39. SATOH T, Wang L, Espinosa-Diez C, Wang B, et al
    Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Down Regulation of sGC and Contributes to Exercise-Induced Pulmonary Hypertension in HFpEF.
    Circulation. 2021 Jun 23. doi: 10.1161/CIRCULATIONAHA.121.053889.
    PubMed     Abstract available


  40. SUN F, Wang G, Pradhan A, Xu K, et al
    Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia.
    Circulation. 2021 Jun 11. doi: 10.1161/CIRCULATIONAHA.121.053980.
    PubMed     Abstract available


  41. BISSERIER M, Mathiyalagan P, Zhang S, Elmastour F, et al
    Regulation of The Methylation and Expression Levels of the BMPR2 Gene by SIN3a As A Novel Therapeutic Mechanism in Pulmonary Arterial Hypertension.
    Circulation. 2021 Jun 3. doi: 10.1161/CIRCULATIONAHA.120.047978.
    PubMed     Abstract available


    April 2021
  42. HOWDEN EJ, Ruiz-Carmona S, Claeys M, de Bosscher R, et al
    Oxygen Pathway Limitations in Patients with Chronic Thromboembolic Pulmonary Hypertension.
    Circulation. 2021 Apr 15. doi: 10.1161/CIRCULATIONAHA.120.052899.
    PubMed     Abstract available


    March 2021
  43. LI D, Shao NY, Moonen JR, Zhao Z, et al
    ALDH1A3 Coordinates Metabolism with Gene Regulation in Pulmonary Arterial Hypertension.
    Circulation. 2021 Mar 25. doi: 10.1161/CIRCULATIONAHA.120.048845.
    PubMed     Abstract available


  44. ZHU L, Liu F, Hao Q, Feng T, et al
    Dietary Geranylgeranyl Pyrophosphate Counteracts the Benefits of Statin Therapy in Experimental Pulmonary Hypertension.
    Circulation. 2021 Mar 4. doi: 10.1161/CIRCULATIONAHA.120.046542.
    PubMed     Abstract available


    July 2020
  45. SHEN H, Zhang J, Wang C, Jain PP, et al
    MDM2-Mediated Ubiquitination of ACE2 Contributes to the Development of Pulmonary Arterial Hypertension.
    Circulation. 2020 Jul 28. doi: 10.1161/CIRCULATIONAHA.120.048191.
    PubMed     Abstract available


  46. OMURA J, Habbout K, Shimauchi T, Wu WH, et al
    Identification of The Long Non-Coding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension.
    Circulation. 2020 Jul 23. doi: 10.1161/CIRCULATIONAHA.120.047626.
    PubMed     Abstract available


  47. ARCHER SL, Sharp WW, Weir EK
    Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications.
    Circulation. 2020;142:101-104.
    PubMed    


    May 2020
  48. HOFFMANN F, Limper U, Zaha VG, Reuter H, et al
    Evolution of Pulmonary Hypertension During Severe Sustained Hypoxia.
    Circulation. 2020;141:1504-1506.
    PubMed    


    March 2020
  49. POTUS F, Pauciulo MW, Cook EK, Zhu N, et al
    Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.
    Circulation. 2020 Mar 20. doi: 10.1161/CIRCULATIONAHA.119.044320.
    PubMed     Abstract available


    February 2020
  50. ROSENKRANZ S, Howard LS, Gomberg-Maitland M, Hoeper MM, et al
    Systemic Consequences of Pulmonary Hypertension and Right-Sided Heart Failure.
    Circulation. 2020;141:678-693.
    PubMed     Abstract available


    January 2020
  51. GERGES C, Gerges M, Friewald R, Fesler P, et al
    Microvascular Disease in Chronic Thromboembolic Pulmonary Hypertension: Hemodynamic Phenotyping and Histomorphometric Assessment.
    Circulation. 2020 Jan 3. doi: 10.1161/CIRCULATIONAHA.119.041515.
    PubMed     Abstract available


    October 2019
  52. RUOPP NF, Farber HW
    The New World Symposium on Pulmonary Hypertension Guidelines: Should Twenty-One Be the New Twenty-Five?
    Circulation. 2019;140:1134-1136.
    PubMed    


    August 2019
  53. TIAN W, Jiang X, Sung YK, Shuffle E, et al
    Phenotypically-Silent Bone Morphogenetic Protein Receptor 2 (Bmpr2) Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing The Risk for Neointimal Transformation.
    Circulation. 2019 Aug 29. doi: 10.1161/CIRCULATIONAHA.119.040629.
    PubMed     Abstract available


  54. KHIRFAN G, Ahmed MK, Almaaitah S, Almoushref A, et al
    Comparison of Different Methods to Estimate Cardiac Index in Pulmonary Arterial Hypertension.
    Circulation. 2019;140:705-707.
    PubMed    


  55. NADEAU V, Bonnet S, Paulin R
    Letter by Nadeau et al Regarding Article, "Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension".
    Circulation. 2019;140:e286-e287.
    PubMed    


  56. MENDES-FERREIRA P, Manaud G, Perros F
    Response by Mendes-Ferreira et al to Letter Regarding Article, "Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension".
    Circulation. 2019;140:e288-e289.
    PubMed    


    April 2019
  57. CHIN KM, Rubin LJ, Channick R, Di Scala L, et al
    Association of NT-proBNP and Long-Term Outcome in Patients with Pulmonary Arterial Hypertension: Insights from the Phase III GRIPHON Study.
    Circulation. 2019 Apr 15. doi: 10.1161/CIRCULATIONAHA.118.039360.
    PubMed     Abstract available


    March 2019
  58. MA Z, Yu YR, Badea CT, Kovacs JJ, et al
    Vascular Endothelial Growth Factor Receptor 3 Regulates Endothelial Function Through beta-Arrestin 1.
    Circulation. 2019;139:1629-1642.
    PubMed     Abstract available


    January 2019
  59. SCHOMBURG L, Melander O
    Letter by Schomburg and Melander Regarding Article, "Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension: A Possible Novel Therapeutic Target".
    Circulation. 2019;139:722-723.
    PubMed    


  60. KIKUCHI N, Satoh K, Saito Y, Shimokawa H, et al
    Response by Kikuchi et al Regarding Article, "Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension: A Possible Novel Therapeutic Target".
    Circulation. 2019;139:724-725.
    PubMed    


  61. ANDERSEN S, Nielsen-Kudsk JE, Vonk Noordegraaf A, de Man FS, et al
    Right Ventricular Fibrosis.
    Circulation. 2019;139:269-285.
    PubMed     Abstract available


  62. GATZOULIS MA, Landzberg M, Beghetti M, Berger RM, et al
    Evaluation of Macitentan in Patients With Eisenmenger Syndrome.
    Circulation. 2019;139:51-63.
    PubMed     Abstract available


    December 2018
  63. YUAN K, Shamskhou EA, Orcholski ME, Nathan A, et al
    Loss of Endothelial Derived WNT5A is Associated with Reduced Pericyte Recruitment and Small Vessel Loss in Pulmonary Arterial Hypertension.
    Circulation. 2018 Dec 11. doi: 10.1161/CIRCULATIONAHA.118.037642.
    PubMed     Abstract available


    October 2018
  64. HAUTEFORT A, Mendes-Ferreira P, Sabourin J, Manaud G, et al
    Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension.
    Circulation. 2018 Oct 4. doi: 10.1161/CIRCULATIONAHA.118.033744.
    PubMed     Abstract available


    February 2018
  65. CHEN KH, Dasgupta A, Lin J, Potus F, et al
    Epigenetic Dysregulation of the Drp1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
    Circulation. 2018 Feb 5. pii: CIRCULATIONAHA.117.031258.
    PubMed     Abstract available


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