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Parkinson's Disease

Free Subscription Articles published in J Biol Chem Retrieve available abstracts of 44 articles: HTML format Text format

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January 2012
1. MATENIA D , Hempp C, Timm T, Eikhof A, et al
   Microtubule affinity regulating kinase 2 (MARK2) turns PTEN-induced kinase 1 (PINK1) on at T313, a mutation site in Parkinson's disease: Effects on mitochondrial transport.
   J Biol Chem. 2012.
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2. KIM K , Kim SH, Kim J, Kim H, et al
   Glutathione S-transferase Omega 1 Activity is Sufficient to Suppress Neurodegeneration in a Drosophila Model of Parkinson's Disease.
   J Biol Chem. 2012.
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   December 2011
3. LE HT , Gautier V, Kthiri F, Malki A, et al
   YajL, the prokaryotic homolog of the Parkinsonism associated protein DJ-1 functions as a covalent chaperone for the thiol proteome.
   J Biol Chem. 2011.
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   October 2011
4. REN H , Fu K, Wang D, Mu C, et al
   Oxidized DJ-1 interacts with the mitochondrial protein BCL-XL.
   J Biol Chem. 2011;286:35308-17.
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5. PEMBERTON S , Madiona K, Pieri L, Kabani M, et al
   Hsc70 protein interaction with soluble and fibrillar alpha-synuclein.
   J Biol Chem. 2011;286:34690-9.
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   September 2011
6. OLAH J , Vincze O, Virok D, Simon D, et al
   Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein.
   J Biol Chem. 2011;286:34088-100.
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7. LAMBERTO GR , Torres-Monserrat V, Bertoncini CW, Salvatella X, et al
   Toward the discovery of effective polycyclic inhibitors of alpha-synuclein amyloid assembly.
   J Biol Chem. 2011;286:32036-44.
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   July 2011
8. DELEERSNIJDER A , Van Rompuy AS, Desender L, Pottel H, et al
   Comparative analysis of different peptidyl-prolyl isomerases reveals FK506-binding protein 12 as the most potent enhancer of alpha-synuclein aggregation.
   J Biol Chem. 2011;286:26687-701.
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9. ANDERSON DG , Mariappan SV, Buettner GR, Doorn JA, et al
   Oxidation of 3,4-dihydroxyphenylacetaldehyde, a toxic dopaminergic metabolite, to a semiquinone radical and an ortho-quinone.
   J Biol Chem. 2011;286:26978-86.
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10. CHEW KC , Ang ET, Tai YK, Tsang F, et al
    Enhanced autophagy from chronic toxicity of iron and mutant A53T {alpha}-synuclein: Implications for neuronal cell death in Parkinson's disease.
    J Biol Chem. 2011.
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11. MENDEZ JA , Bourque MJ, Fasano C, Kortleven C, et al
    Somatodendritic dopamine release requires synaptotagmin 4 and 7 and the participation of voltage-gated calcium channels.
    J Biol Chem. 2011;286:23928-37.
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    June 2011
12. YAP TL , Gruschus JM, Velayati A, Westbroek W, et al
    {alpha}-Synuclein Interacts with Glucocerebrosidase Providing a Molecular Link between Parkinson and Gaucher Diseases.
    J Biol Chem. 2011.
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    May 2011
13. CHAN D , Citro A, Cordy JM, Shen GC, et al
    Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2).
    J Biol Chem. 2011;286:16140-9.
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    April 2011
14. CHOI DH , Kim YJ, Kim YG, Joh TH, et al
    Role of matrix metalloproteinase 3-mediated alpha-synuclein cleavage in dopaminergic cell death.
    J Biol Chem. 2011;286:14168-77.
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15. SHVADCHAK VV , Falomir-Lockhart LJ, Yushchenko DA, Jovin TM, et al
    Specificity and kinetics of alpha-synuclein binding to model membranes determined with fluorescent excited state intramolecular proton transfer (ESIPT) probe.
    J Biol Chem. 2011;286:13023-32.
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16. NAKAMURA K , Nemani VM, Azarbal F, Skibinski G, et al
    Direct membrane association drives mitochondrial fission by the Parkinson Disease-associated protein {alpha}-synuclein.
    J Biol Chem. 2011.
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    March 2011
17. CHOUBEY V , Safiulina D, Vaarmann A, Cagalinec M, et al
    Mutant A53T alpha-synuclein induces neuronal death by increasing mitochondrial autophagy.
    J Biol Chem. 2011;286:10814-24.
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18. GENTILELLA A , Khalili K
    BAG3 expression in glioblastoma cells promotes accumulation of ubiquitinated clients in an Hsp70-dependent manner.
    J Biol Chem. 2011;286:9205-15.
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19. ZHOU W , Bercury K, Cummiskey J, Luong N, et al
    Phenylbutyrate upregulates DJ-1 and protects neurons in cell culture and in animal models of Parkinson's disease.
    J Biol Chem. 2011.
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    February 2011
20. WANG H , Song P, Du L, Tian W, et al
    Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson's disease.
    J Biol Chem. 2011.
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    January 2011
21. DANIELSON SR , Held JM, Oo M, Riley R, et al
    Quantitative mapping of reversible mitochondrial Complex I cysteine oxidation in a Parkinson's disease mouse model.
    J Biol Chem. 2011.
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    December 2010
22. MACHIYA Y , Hara S, Arawaka S, Fukushima S, et al
    Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner.
    J Biol Chem. 2010;285:40732-44.
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23. MURATA H , Sakaguchi M, Jin Y, Sakaguchi Y, et al
    A new cytosolic pathway from a Parkinson's disease-associated kinase, BRPK/PINK1: activation of AKT via MTORC2.
    J Biol Chem. 2010.
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24. ISHIKAWA S , Taira T, Takahashi-Niki K, Niki T, et al
    Human DJ-1-specific transcriptional activation of tyrosine hydroxylase gene.
    J Biol Chem. 2010;285:39718-31.
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25. HINAULT MP , Cuendet AF, Mattoo RU, Mensi M, et al
    Stable alpha-synuclein oligomers strongly inhibit chaperone activity of the Hsp70 system by weak interactions with J-domain co-chaperones.
    J Biol Chem. 2010;285:38173-82.
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26. ZIBAEE S , Fraser G, Jakes R, Owen D, et al
    Human beta-synuclein rendered fibrillogenic by designed mutations.
    J Biol Chem. 2010;285:38555-67.
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27. QURESHI HY , Paudel HK
    Parkinsonian neurotoxin MPTP and alpha-synuclein mutations promote tau protein phosphorylation at Ser262 and destabilize microtubule cytoskeleton in vitro.
    J Biol Chem. 2010.
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    October 2010
28. BATABYAL D , McKenzie JL, Johnson KA
    Role of histidine 932 of the human mitochondrial DNA polymerase in nucleotide discrimination and inherited disease.
    J Biol Chem. 2010;285:34191-201.
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    September 2010
29. SCHWINDINGER WF , Mihalcik LJ, Giger KE, Betz KS, et al
    Adenosine A2A receptor signaling and golf assembly show a specific requirement for the gamma7 subtype in the striatum.
    J Biol Chem. 2010;285:29787-96.
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30. GEORGIEVA ER , Ramlall TF, Borbat PP, Freed JH, et al
    The lipid-binding domain of wild type and mutant alpha-synuclein: compactness and interconversion between the broken and extended helix forms.
    J Biol Chem. 2010;285:28261-74.
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    July 2010
31. KIM KS , Park JY, Jou I, Park SM, et al
    Regulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial cells.
    J Biol Chem. 2010;285:21416-25.
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32. LI X , Moore DJ, Xiong Y, Dawson TM, et al
    Reevaluation of phosphorylation sites in the Parkinson's disease associated leucine rich repeat kinase-2.
    J Biol Chem. 2010.
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    June 2010
33. EINHOLM AP , Toustrup-Jensen MS, Holm R, Andersen JP, et al
    The rapid-onset dystonia Parkinsonism mutation D923N of the Na+,K+-ATPase alpha-3 isoform disrupts Na+ interaction at the third Na+ site.
    J Biol Chem. 2010.
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34. LOU H , Montoya SE, Alerte TN, Wang J, et al
    Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.
    J Biol Chem. 2010;285:17648-61.
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    April 2010
35. MAK SK , McCormack AL, Manning-Bog AB, Cuervo AM, et al
    Lysosomal degradation of alpha-synuclein in vivo.
    J Biol Chem. 2010;285:13621-9.
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36. FRANCISCO AB , Singh R, Li S, Vani AK, et al
    Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality.
    J Biol Chem. 2010;285:13694-703.
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37. DOXAKIS E
    Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153.
    J Biol Chem. 2010;285:12726-34.
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38. FOTI R , Zucchelli S, Biagioli M, Roncaglia P, et al
    Parkinson's disease-associated DJ-1 is required for the expression of the Glial cell line-derived neurotrophic factor receptor RET in human neuroblastoma cells.
    J Biol Chem. 2010.
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39. CUI M , Tang X, Christian WV, Yoon Y, et al
    Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1.
    J Biol Chem. 2010;285:11740-52.
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40. LEE M , Tazzari V, Giustarini D, Rossi R, et al
    Effects of hydrogen sulfide-releasing L-DOPA derivatives on glial activation: potential for treating Parkinson disease.
    J Biol Chem. 2010.
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    February 2010
41. KTHIRI F , Le HT, Gautier V, Caldas T, et al
    Protein aggregation in a mutant deficient in YajL,the bacterial homolog of the parkinsonism-associated protein DJ-1.
    J Biol Chem. 2010.
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    January 2010
42. COURTOIS ET , Castillo CG, Seiz EG, Ramos M, et al
    In vitro and in vivo enhanced generation of human A9 dopamine neurons from neural stem cells by Bcl-XL.
    J Biol Chem. 2010.
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43. MBEFO MK , Paleologou KE, Boucharaba A, Oueslati A, et al
    Phosphorylation of synucleins by members of the Polo-like kinase family.
    J Biol Chem. 2010;285:2807-22.
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    December 2009
44. SEN S , Webber PJ, West AB
    Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization.
    J Biol Chem. 2009;284:36346-56.
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