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Parkinson's Disease

Free Subscription Articles published in J Biol Chem Retrieve available abstracts of 42 articles: HTML format Text format

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February 2010
1. KTHIRI F , Le HT, Gautier V, Caldas T, et al
   Protein aggregation in a mutant deficient in YajL,the bacterial homolog of the parkinsonism-associated protein DJ-1.
   J Biol Chem. 2010.
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   January 2010
2. MBEFO MK , Paleologou KE, Boucharaba A, Oueslati A, et al
   Phosphorylation of synucleins by members of the Polo-like kinase family.
   J Biol Chem. 2010;285:2807-22.
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   December 2009
3. SEN S , Webber PJ, West AB
   Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization.
   J Biol Chem. 2009;284:36346-56.
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   September 2009
4. SETTIVARI R , Levora J, Nass R
   The divalent metal transporter homologues SMF-1/2 mediates dopamine neuron sensitivity in caenorhabditis elegans models of manganism and Parkinson's disease.
   J Biol Chem. 2009.
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5. ENDO R , Saito T, Asada A, Kawahara H, et al
   Commitment of 1-methyl-4-phenylpyrinidinium ion-induced neuronal cell death by proteasome-mediated degradation of p35 cyclin-dependent kinase 5 activator.
   J Biol Chem. 2009;284:26029-39.
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6. FALSONE SF , Kungl AJ, Rek A, Cappai R, et al
   The molecular chaperone Hsp90 modulates intermediate steps of amyloid assembly of the Parkinson-related protein alpha-synuclein.
   J Biol Chem. 2009.
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7. FISHMAN-JACOB T , Reznichenko L, Youdim MB, Mandel SA, et al
   A sporadic parkinson's disease model via silencing of the ubiquitin-proteasome/E3-ligase component, SKP1A.
   J Biol Chem. 2009.
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   August 2009
8. LEE DW , Rajagopalan S, Siddiq A, Gwiazda R, et al
   Inhibition of prolyl hydroxylase protects against MPTP-induced neurotoxicity: Model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson's disease.
   J Biol Chem. 2009.
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   May 2009
9. WAAK J , Weber SS, Gorner K, Schall C, et al
   Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1.
   J Biol Chem. 2009;284:14245-57.
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10. CHIGURUPATI S , Wei Z, Belal C, Vandermey M, et al
    The homocysteine-inducible endoplasmic reticulum stress protein counteracts calcium store depletion and induction of C/EBP homologous protein in a neurotoxin model of Parkinson's disease.
    J Biol Chem. 2009.
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11. DAGDA RK , Cherra SJ 3rd, Kulich SM, Tandon A, et al
    Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission.
    J Biol Chem. 2009;284:13843-55.
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    April 2009
12. EMADI S , Kasturirangan S, Wang MS, Schulz P, et al
    Detecting morphologically distinct oligomeric forms of alpha-synuclein.
    J Biol Chem. 2009;284:11048-58.
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13. BAYIR H , Kapralov AA, Jiang J, Huang Z, et al
    Peroxidase mechanism of lipid dependent cross-linking of synuclein with cytochrome c: protection against apoptosis versus delayed oxidative stress in Parkinson's disease.
    J Biol Chem. 2009.
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14. HRISTOVA VA , Beasley SA, Rylett RJ, Shaw GS, et al
    Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile parkinson's related E3 ligase parkin.
    J Biol Chem. 2009.
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    March 2009
15. YONETANI M , Nonaka T, Masuda M, Inukai Y, et al
    Conversion of wild-type alpha-synuclein into mutant-type fibrils and its propagation in the presence of A30P mutant.
    J Biol Chem. 2009;284:7940-50.
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16. HASADSRI L , Kreuter J, Hattori H, Iwasaki T, et al
    Functional protein delivery into neurons using polymeric nanoparticles.
    J Biol Chem. 2009;284:6972-81.
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    February 2009
17. REN Y , Jiang H, Yang F, Nakaso K, et al
    Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation.
    J Biol Chem. 2009;284:4009-17.
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    January 2009
18. SCHMID AW , Chiappe D, Pignat V, Grimminger V, et al
    Dissecting the mechanisms of tissue transglutaminase-induced cross-linking of alpha-synuclein: Implications for the pathogenesis of Parkinson's disease.
    J Biol Chem. 2009.
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19. PERLMUTTER JD , Braun AR, Sachs JN
    Curvature dynamics of alpha -synuclein familial Parkinson's disease mutants: Molecular simulations of the micelle- and bilayer-bound forms.
    J Biol Chem. 2009.
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20. BLACKINTON J , Lakshminarasimhan M, Thomas KJ, Ahmad R, et al
    Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1.
    J Biol Chem. 2009.
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    December 2008
21. LIU M , Aneja R, Sun X, Xie S, et al
    Parkin regulates Eg5 expression by Hsp70 ubiquitination-dependent inactivation of c-Jun NH2-terminal kinase.
    J Biol Chem. 2008;283:35783-8.
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22. CHOU AP , Maidment N, Klintenberg R, Casida JE, et al
    Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome.
    J Biol Chem. 2008;283:34696-703.
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23. CHA SS , Jung HI, Jeon H, An YJ, et al
    Crystal structure of filamentous aggregates of human DJ-1 formed in an inorganic phosphate-dependent manner.
    J Biol Chem. 2008;283:34069-75.
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    November 2008
24. PARK KM , Yule DI, Bowers WJ
    Tumor necrosis factor-alpha potentiates intraneuronal Ca2+ signaling via regulation of the inositol 1,4,5-trisphosphate receptor.
    J Biol Chem. 2008;283:33069-79.
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    October 2008
25. LIU X , Yamada N, Maruyama W, Osawa T, et al
    Formation of dopamine adducts derived from brain polyunsaturated fatty acids: Mechanism for Parkinson's disease.
    J Biol Chem. 2008.
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26. ZAARUR N , Meriin AB, Gabai VL, Sherman MY, et al
    Triggering aggresome formation. Dissecting aggresome-targeting and aggregation signals in synphilin 1.
    J Biol Chem. 2008;283:27575-84.
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    August 2008
27. FU Y , Buryanovskyy L, Zhang Z
    Quinone reductase 2 is a catechol quinone reductase.
    J Biol Chem. 2008;283:23829-35.
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28. VOGIATZI T , Xilouri M, Vekrellis K, Stefanis L, et al
    Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells.
    J Biol Chem. 2008;283:23542-56.
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    June 2008
29. KABUTA T , Furuta A, Aoki S, Furuta K, et al
    Aberrant interaction between Parkinson's disease-associated mutant UCH-L1 and the lysosomal receptor for chaperone-mediated autophagy.
    J Biol Chem. 2008;.
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30. WANG H , Ghosh A, Baigude H, Yang CS, et al
    Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression.
    J Biol Chem. 2008;283:15845-52.
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    April 2008
31. KOSTKA M , Hogen T, Danzer KM, Levin J, et al
    Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers.
    J Biol Chem. 2008;283:10992-1003.
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32. ZHOU W , Milder JB, Freed CR
    Transgenic mice overexpressing tyrosine-to-cysteine mutant human alpha-synuclein: a progressive neurodegenerative model of diffuse Lewy body disease.
    J Biol Chem. 2008;283:9863-70.
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33. GREGGIO E , Zambrano I, Kaganovich A, Beilina A, et al
    The Parkinson's disease associated Leucine rich repeat kinase 2 (LRRK2) is a dimer that undergoes intra-molecular autophosphorylation.
    J Biol Chem. 2008;.
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34. TESSARI I , Bisaglia M, Valle F, Samori B, et al
    The reaction of alpha -synuclein with tyrosinase: Possible implications for Parkinson disease.
    J Biol Chem. 2008;.
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    March 2008
35. BROWN AM , Baucum AJ, Bass MA, Colbran RJ, et al
    Association of protein phosphatase 1gamma 1 with spinophilin suppresses phosphatase activity in a Parkinson's disease model.
    J Biol Chem. 2008;.
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36. MUCHOWSKI PJ , Ramsden R, Nguyen Q, Arnett EE, et al
    Noninvasive measurement of protein aggregation by mutant huntingtin fragments or alpha-synuclein in the lens.
    J Biol Chem. 2008;283:6330-6.
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    February 2008
37. FEI Q , McCormack AL, Di Monte DA, Ethell DW, et al
    Paraquat neurotoxicity is mediated by a Bak-dependent mechanism.
    J Biol Chem. 2008;283:3357-64.
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38. LEE YM , Park SH, Shin DI, Hwang JY, et al
    Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson's disease.
    J Biol Chem. 2008;.
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39. DEVI L , Raghavendran V, Prabhu BM, Avadhani NG, et al
    Mitochondrial import and accumulation of alpha -synuclein impairs complex I in human dopaminergic neuronal cultures and Parkinson's disease brain.
    J Biol Chem. 2008;.
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    January 2008
40. KAWAHARA K , Hashimoto M, Bar-On P, Ho GJ, et al
    alpha -synuclein aggregates Interfere With Parkin solubility and distribution: Role in the pathogenesis of Parkinson's disease.
    J Biol Chem. 2008;.
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    November 2007
41. WENG Z , Signore AP, Gao Y, Wang S, et al
    Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signaling.
    J Biol Chem. 2007;282:34479-91.
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42. WOODS WS , Boettcher JM, Zhou DH, Kloepper KD, et al
    Conformation-specific binding of alpha-synuclein to novel protein partners detected by phage display and NMR spectroscopy.
    J Biol Chem. 2007;282:34555-67.
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