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	Amedeo Prize 2008 The 21 Finalists

Parkinson's Disease

Free Subscription Articles published in J Biol Chem Retrieve available abstracts of 30 articles: HTML format

Single Articles

April 2008
1. GREGGIO E , Zambrano I, Kaganovich A, Beilina A, et al
   The Parkinson's disease associated Leucine rich repeat kinase 2 (LRRK2) is a dimer that undergoes intra-molecular autophosphorylation.
   J Biol Chem. 2008;.
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2. TESSARI I , Bisaglia M, Valle F, Samori B, et al
   The reaction of alpha -synuclein with tyrosinase: Possible implications for Parkinson disease.
   J Biol Chem. 2008;.
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   March 2008
3. BROWN AM , Baucum AJ, Bass MA, Colbran RJ, et al
   Association of protein phosphatase 1gamma 1 with spinophilin suppresses phosphatase activity in a Parkinson's disease model.
   J Biol Chem. 2008;.
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   February 2008
4. FEI Q , McCormack AL, Di Monte DA, Ethell DW, et al
   Paraquat neurotoxicity is mediated by a Bak-dependent mechanism.
   J Biol Chem. 2008;283:3357-64.
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5. LEE YM , Park SH, Shin DI, Hwang JY, et al
   Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson's disease.
   J Biol Chem. 2008;.
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6. DEVI L , Raghavendran V, Prabhu BM, Avadhani NG, et al
   Mitochondrial import and accumulation of alpha -synuclein impairs complex I in human dopaminergic neuronal cultures and Parkinson's disease brain.
   J Biol Chem. 2008;.
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   January 2008
7. KAWAHARA K , Hashimoto M, Bar-On P, Ho GJ, et al
   alpha -synuclein aggregates Interfere With Parkin solubility and distribution: Role in the pathogenesis of Parkinson's disease.
   J Biol Chem. 2008;.
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   November 2007
8. WENG Z , Signore AP, Gao Y, Wang S, et al
   Leptin protects against 6-hydroxydopamine-induced dopaminergic cell death via mitogen-activated protein kinase signaling.
   J Biol Chem. 2007;282:34479-91.
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9. WOODS WS , Boettcher JM, Zhou DH, Kloepper KD, et al
   Conformation-specific binding of alpha-synuclein to novel protein partners detected by phage display and NMR spectroscopy.
   J Biol Chem. 2007;282:34555-67.
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   July 2007
10. AOYAGI H , Hasegawa M, Tamaoka A
    Fibrillogenic nuclei composed of P301L mutant tau induce elongation of P301L tau but not wild-type tau.
    J Biol Chem. 2007;282:20309-18.
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    May 2007
11. HERRERA FE , Zucchelli S, Jezierska A, Lavina ZS, et al
    On the oligomeric state of DJ-1 protein and its mutants associated with Parkinson's Disease: a combined computational and in vitro study.
    J Biol Chem. 2007;.
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12. GORNER K , Holtorf E, Waak J, Pham TT, et al
    Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1.
    J Biol Chem. 2007;282:13680-91.
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    April 2007
13. AVRAHAM E , Rott R, Liani E, Szargel R, et al
    Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation.
    J Biol Chem. 2007;282:12842-50.
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    February 2007
14. QIN Z , Hu D, Han S, Reaney SH, et al
    Effect of 4-hydroxy-2-nonenal modification on alpha-synuclein aggregation.
    J Biol Chem. 2007;282:5862-70.
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15. SARKAR S , Davies JE, Huang Z, Tunnacliffe A, et al
    Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
    J Biol Chem. 2007;282:5641-52.
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    January 2007
16. MERAY RK , Lansbury PT Jr
    Reversible monoubiquitination regulates the Parkinson's disease-associated ubiquitin hydrolase UCH-L1.
    J Biol Chem. 2007;.
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    December 2006
17. YAMAMOTO N , Sawada H, Izumi Y, Kume T, et al
    Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: Relevance to Parkinson disease.
    J Biol Chem. 2006;.
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    November 2006
18. WILHELM M , Xu Z, Kukekov NV, Gire S, et al
    Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model.
    J Biol Chem. 2006;.
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    October 2006
19. WISLET-GENDEBIEN S , D'Souza C, Kawarai T, St George-Hyslop P, et al
    Cytosolic proteins regulate alpha-synuclein dissociation from presynaptic membranes.
    J Biol Chem. 2006;281:32148-55.
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    June 2006
20. CHALOVICH EM , Zhu JH, Caltagarone J, Bowser R, et al
    Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells.
    J Biol Chem. 2006;281:17870-81.
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    April 2006
21. RODACKER V , Toustrup-Jensen M, Vilsen B
    Mutations Phe785Leu and Thr618Met in Na+,K+-ATPase, associated with familial rapid-onset dystonia parkinsonism, interfere with Na+ interaction by distinct mechanisms.
    J Biol Chem. 2006;.
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22. DAHM CC , Moore K, Murphy MP
    Persistent S-nitrosation of complex I and other mitochondrial membrane proteins by S-nitrosothiols but not nitric oxide or peroxynitrite: implications for the interaction of nitric oxide with mitochondria.
    J Biol Chem. 2006;281:10056-65.
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23. ALVES DA COSTA C , Dunys J, Brau F, Wilk S, et al
    6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes alpha-synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation.
    J Biol Chem. 2006;281:9824-31.
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24. KAMP F , Beyer K
    Binding of alpha-synuclein affects the lipid packing in bilayers of small vesicles.
    J Biol Chem. 2006;281:9251-9.
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    March 2006
25. JIANG H , Jiang Q, Liu W, Feng J, et al
    Parkin suppresses the expression of monoamine oxidases.
    J Biol Chem. 2006;281:8591-9.
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26. SEO BB , Nakamaru-Ogiso E, Flotte TR, Matsuno-Yagi A, et al
    In vivo complementation of complex I by the yeast Ndi1 enzyme: possible application for treatment of Parkinson's disease.
    J Biol Chem. 2006;.
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27. HANROTT K , Gudmunsen L, O'Neill MJ, Wonnacott S, et al
    6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta.
    J Biol Chem. 2006;281:5373-82.
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    February 2006
28. MATSUDA N , Kitami T, Suzuki T, Mizuno Y, et al
    Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro.
    J Biol Chem. 2006;281:3204-9.
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29. UM JW , Min do S, Rhim H, Kim J, et al
    Parkin ubiquitinates and promotes the degradation of RanBP2.
    J Biol Chem. 2006;281:3595-603.
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30. LEE CH , Kim HJ, Lee JH, Cho HJ, et al
    Dequalinium-induced protofibril formation of alpha-synuclein.
    J Biol Chem. 2006;281:3463-72.
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