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Articles published in Eur J Pharmacol

Retrieve available abstracts of 58 articles:
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Single Articles


    March 2024
  1. ZENG J, Gao WW, Yang H, Wang YN, et al
    Sodium tanshinone IIA sulfonate suppresses microglia polarization and neuroinflammation possibly via regulating miR-125b-5p/STAT3 axis to ameliorate neuropathic pain.
    Eur J Pharmacol. 2024 Mar 27:176523. doi: 10.1016/j.ejphar.2024.176523.
    PubMed     Abstract available


  2. ISHIDA H, Yamaguchi M, Saito SY, Furukawa T, et al
    Corrigendum to "Na(+)-dependent inactivation of vascular Na(+)/Ca(2+) exchanger responsible for reduced peripheral blood flow in neuropathic pain model" [Eur. J. Pharmacol. 910 (2021) 174448].
    Eur J Pharmacol. 2024 Mar 14:176495. doi: 10.1016/j.ejphar.2024.176495.
    PubMed    


  3. CHEN L, Hua B, He Q, Han Z, et al
    Curcumin analogue NL04 inhibits spinal cord central sensitization in rats with bone cancer pain by inhibiting NLRP3 inflammasome activation and reducing IL-1beta production.
    Eur J Pharmacol. 2024;970:176480.
    PubMed     Abstract available


    February 2024
  4. ANTUNES FTT, Huang S, Chen L, Zamponi GW, et al
    Effect of ABT-639 on Cav3.2 channel activity and its analgesic actions in mouse models of inflammatory and neuropathic pain.
    Eur J Pharmacol. 2024 Feb 9:176416. doi: 10.1016/j.ejphar.2024.176416.
    PubMed     Abstract available


  5. BAGGIO DF, da Luz FMR, Zortea JM, Lejeune VBP, et al
    Sex differences in carbamazepine effects in a rat model of trigeminal neuropathic pain.
    Eur J Pharmacol. 2024 Feb 2:176386. doi: 10.1016/j.ejphar.2024.176386.
    PubMed     Abstract available


    December 2023
  6. JU Y, Wang CM, Yu JJ, Li X, et al
    Higenamine inhibits acute and chronic inflammatory pain through modulation of TRPV4 channels.
    Eur J Pharmacol. 2023 Dec 26:176295. doi: 10.1016/j.ejphar.2023.176295.
    PubMed     Abstract available


  7. GARMAN A, Ash AM, Kokkinos EK, Nerland D, et al
    Novel hippocampal genes involved in enhanced susceptibility to chronic pain-induced behavioral emotionality.
    Eur J Pharmacol. 2023;964:176273.
    PubMed     Abstract available


    November 2023
  8. WANG J, Ru QM, Yu XH, Wang C, et al
    Direct inhibition of microglial activation by a mu receptor selective agonist alleviates inflammatory-induced pain hypersensitivity.
    Eur J Pharmacol. 2023 Nov 9:176182. doi: 10.1016/j.ejphar.2023.176182.
    PubMed     Abstract available


  9. SONG S, Wang Q, Qu Y, Gao W, et al
    Pregabalin inhibits purinergic P2Y(2) receptor and TRPV4 to suppress astrocyte activation and to relieve neuropathic pain.
    Eur J Pharmacol. 2023 Nov 2:176140. doi: 10.1016/j.ejphar.2023.176140.
    PubMed     Abstract available


    September 2023
  10. HOSCH NG, Martins BB, Alcantara QA, Bufalo MC, et al
    Wnt signaling is involved in crotalphine-induced analgesia in a rat model of neuropathic pain.
    Eur J Pharmacol. 2023 Sep 20:176058. doi: 10.1016/j.ejphar.2023.176058.
    PubMed     Abstract available


    August 2023
  11. ZHANG WJ, Liu SC, Ming LG, Yu JW, et al
    Potential role of Schwann cells in neuropathic pain.
    Eur J Pharmacol. 2023 Aug 2:175955. doi: 10.1016/j.ejphar.2023.175955.
    PubMed     Abstract available


    July 2023
  12. BASU P, Maier C, Averitt DL, Basu A, et al
    NLR family pyrin domain containing 3 (NLRP3) inflammasomes and peripheral neuropathic pain - Emphasis on microRNAs (miRNAs) as important regulators.
    Eur J Pharmacol. 2023 Jul 12:175901. doi: 10.1016/j.ejphar.2023.175901.
    PubMed     Abstract available


  13. ZHENG G, Ren J, Shang L, Bao Y, et al
    Role of autophagy in the pathogenesis and regulation of pain.
    Eur J Pharmacol. 2023 Jul 8:175859. doi: 10.1016/j.ejphar.2023.175859.
    PubMed     Abstract available


    June 2023
  14. YANG L, Fu Q, Yang L, Zhang Y, et al
    HIF-1alpha/MMP-9 promotes spinal cord central sensitization in rats with bone cancer pain.
    Eur J Pharmacol. 2023 Jun 23:175858. doi: 10.1016/j.ejphar.2023.175858.
    PubMed     Abstract available


  15. QI Z, Zhong W, Jiao B, Chen K, et al
    Activation of G-protein-coupled receptor 183 initiates inflammatory pain via macrophage CCL22 secretion.
    Eur J Pharmacol. 2023;954:175872.
    PubMed     Abstract available


    March 2023
  16. ZHANG D, Ma L, Tan X, Deng W, et al
    Intradermal miR-16-5p targets Akt3 and reduces RTX-induced postherpetic neuralgia-mimic pain in mice.
    Eur J Pharmacol. 2023;946:175665.
    PubMed     Abstract available


  17. LIU S, Lan XB, Tian MM, Zhu CH, et al
    Targeting the chemokine ligand 2-chemokine receptor 2 axis provides the possibility of immunotherapy in chronic pain.
    Eur J Pharmacol. 2023 Mar 10:175646. doi: 10.1016/j.ejphar.2023.175646.
    PubMed     Abstract available


    January 2023
  18. NAKAMOTO K, Matsuura W, Tokuyama S
    Nicotine suppresses central post-stroke pain via facilitation of descending noradrenergic neuron through activation of orexinergic neuron.
    Eur J Pharmacol. 2023 Jan 24:175518. doi: 10.1016/j.ejphar.2023.175518.
    PubMed     Abstract available


    November 2022
  19. MELO ISF, Ziviani VP, Barbosa BCM, Rodrigues FF, et al
    Synthesis of 2-(2-(4-thioxo-3H-1,2-dithiole-5-yl) phenoxy)ethyl)isoindole-1,3-thione, a novel hydrogen sulfide-releasing phthalimide hybrid, and evaluation of its activity in models of inflammatory pain.
    Eur J Pharmacol. 2022;938:175409.
    PubMed     Abstract available


    October 2022
  20. CAO J, Liu X, Liu JX, Zhao S, et al
    Inhibition of glutamatergic neurons in layer II/III of the medial prefrontal cortex alleviates paclitaxel-induced neuropathic pain and anxiety.
    Eur J Pharmacol. 2022 Oct 26:175351. doi: 10.1016/j.ejphar.2022.175351.
    PubMed     Abstract available


    September 2022
  21. XU Y, Jiang Z, Chen X
    Mechanisms underlying paclitaxel-induced neuropathic pain: Channels, inflammation and immune regulations.
    Eur J Pharmacol. 2022 Sep 16:175288. doi: 10.1016/j.ejphar.2022.175288.
    PubMed     Abstract available


  22. LIN J, Fang X, Liu F, Zhang Y, et al
    Corrigendum to "P2Y14 receptor in trigeminal ganglion contributes to neuropathic pain in mice" [Eur. J. Pharmacol. 931 (2022) 175211].
    Eur J Pharmacol. 2022 Sep 9:175266. doi: 10.1016/j.ejphar.2022.175266.
    PubMed    


    August 2022
  23. LIN J, Fang X, Liu F, Zhang Y, et al
    P2Y14 receptor in trigeminal ganglion contributes to neuropathic pain in mice.
    Eur J Pharmacol. 2022 Aug 15:175211. doi: 10.1016/j.ejphar.2022.175211.
    PubMed     Abstract available


    June 2022
  24. LI DY, Gao SJ, Sun J, Zhang LQ, et al
    Notch signaling activation contributes to paclitaxel-induced neuropathic pain via activation of A1 astrocytes.
    Eur J Pharmacol. 2022;928:175130.
    PubMed     Abstract available


    May 2022
  25. BLOMS-FUNKE P, Schumacher M, Liu S, Su D, et al
    A novel dual mode-of-action anti-hyperalgesic compound in rats which is neuroprotective and promotes neuroregeneration.
    Eur J Pharmacol. 2022;923:174935.
    PubMed     Abstract available


  26. PATRAD E, Khalighfard S, Khori V, Alizadeh AM, et al
    The other side of the coin: Positive view on the role of opioids in cancer.
    Eur J Pharmacol. 2022;923:174888.
    PubMed     Abstract available


    April 2022
  27. JAIN MR, Patel RB, Prajapati KD, Vyas P, et al
    ZYKR1, a novel, potent, and peripherally selective kappa opioid receptor agonist reduces visceral pain and pruritus in animal models.
    Eur J Pharmacol. 2022 Apr 17:174961. doi: 10.1016/j.ejphar.2022.174961.
    PubMed     Abstract available


  28. SIVAKUMAR D, Ramli R
    GABAergic signalling in modulation of dental pain.
    Eur J Pharmacol. 2022;924:174958.
    PubMed     Abstract available


    March 2022
  29. ARAYA EI, Baggio DF, Koren LO, Schwarting RKW, et al
    Trigeminal neuropathic pain reduces 50-kHz ultrasonic vocalizations in rats, which are restored by analgesic drugs.
    Eur J Pharmacol. 2022;922:174905.
    PubMed     Abstract available


  30. QUEIROZ BFG, Fonseca FCS, Ferreira RCM, Romero TRL, et al
    Analgesia and pain: Dual effect of dopamine on the peripheral nociceptive system is dependent on D2-or D1-like receptor activation.
    Eur J Pharmacol. 2022 Mar 14:174872. doi: 10.1016/j.ejphar.2022.174872.
    PubMed     Abstract available


    February 2022
  31. RODRIGUEZ-PALMA EJ, Castelo-Flores DG, Caram-Salas NL, Salinas-Abarca AB, et al
    Sex-dependent antiallodynic effect of alpha2 adrenergic receptor agonist tizanidine in rats with experimental neuropathic pain.
    Eur J Pharmacol. 2022 Feb 25:174855. doi: 10.1016/j.ejphar.2022.174855.
    PubMed     Abstract available


    January 2022
  32. WANG Y, Qin D, Guo Z, Shi F, et al
    Research progress on the potential novel analgesic BU08028.
    Eur J Pharmacol. 2022;914:174678.
    PubMed     Abstract available


    November 2021
  33. TAMADA M, Ohi Y, Kodama D, Miyazawa K, et al
    Modulation of excitatory synaptic transmissions by TRPV1 in the spinal trigeminal subnucleus caudalis neurons of neuropathic pain rats.
    Eur J Pharmacol. 2021;913:174625.
    PubMed     Abstract available


  34. LI T, Wang L, Zhang L, Li B, et al
    Rotigotine-loaded microspheres exerts the antinociceptive effect via central dopaminergic system.
    Eur J Pharmacol. 2021;910:174443.
    PubMed     Abstract available


    October 2021
  35. ZHAO L, Tao X, Song T
    Astaxanthin alleviates neuropathic pain by inhibiting the MAPKs and NF-kappaB pathways.
    Eur J Pharmacol. 2021;912:174575.
    PubMed     Abstract available


    September 2021
  36. NAFFAA MM, Al-Ewaidat OA
    Ligand modulation of KCNQ-encoded (KV7) potassium channels in the heart and nervous system.
    Eur J Pharmacol. 2021;906:174278.
    PubMed     Abstract available


    August 2021
  37. ISHIDA H, Yamaguchi M, Saito SY, Furukawa T, et al
    Na(+)-dependent inactivation of vascular Na(+)/Ca(2+) exchanger responsible for reduced peripheral blood flow in neuropathic pain model.
    Eur J Pharmacol. 2021;910:174448.
    PubMed     Abstract available


  38. FU J, Xu M, Xu L, Ni H, et al
    Sulforaphane alleviates hyperalgesia and enhances analgesic potency of morphine in rats with cancer-induced bone pain.
    Eur J Pharmacol. 2021;909:174412.
    PubMed     Abstract available


  39. VILLALUZ M, Dunning L, Goodyear CS, Ferrell WR, et al
    Losartan protects endothelium-dependent relaxation in vivo in a murine model of rheumatoid arthritis.
    Eur J Pharmacol. 2021;904:174133.
    PubMed     Abstract available


    July 2021
  40. YANG F, Zou YQ, Li M, Luo WJ, et al
    Intervertebral foramen injection of plerixafor attenuates neuropathic pain after chronic compression of the dorsal root ganglion: Possible involvement of the down-regulation of Nav1.8 and Nav1.9.
    Eur J Pharmacol. 2021;908:174322.
    PubMed     Abstract available


  41. KHAN J, Ali G, Rashid U, Khan R, et al
    Mechanistic evaluation of a novel cyclohexenone derivative's functionality against nociception and inflammation: An in-vitro, in-vivo and in-silico approach.
    Eur J Pharmacol. 2021;902:174091.
    PubMed     Abstract available


    June 2021
  42. GUO ZB, Tang L, Wang LP, Wu HH, et al
    The analgesic effects of ulinastatin either as a single agent or in combination with sufentanil: A novel therapeutic potential for postoperative pain.
    Eur J Pharmacol. 2021;907:174267.
    PubMed     Abstract available


    May 2021
  43. SPRING DE ALMEIDA A, de Barros Bernardes L, Trevisan G
    TRP Channels in Cancer Pain.
    Eur J Pharmacol. 2021 May 17:174185. doi: 10.1016/j.ejphar.2021.174185.
    PubMed     Abstract available


  44. YAO L, Zhang TY, Diao XT, Ma JJ, et al
    Functional expression of glycine receptors in DRG neurons of mice.
    Eur J Pharmacol. 2021;899:174034.
    PubMed     Abstract available


  45. MUCHHALA KH, Jacob JC, Dewey WL, Akbarali HI, et al
    Role of beta-arrestin-2 in short- and long-term opioid tolerance in the dorsal root ganglia.
    Eur J Pharmacol. 2021;899:174007.
    PubMed     Abstract available


    April 2021
  46. ZHANG T, Zhang R, Xu B, Zhang M, et al
    Spinal endomorphins attenuate burn-injury pain in male mice by inhibiting p38 MAPK signaling pathway through the mu-opioid receptor.
    Eur J Pharmacol. 2021;903:174139.
    PubMed     Abstract available


  47. DIAS QUINTAO JL, Reis Gonzaga AC, Galdino G, Lima Romero TR, et al
    TNF-alpha, CXCL-1 and IL-1 beta as activators of the opioid system involved in peripheral analgesic control in mice.
    Eur J Pharmacol. 2021;896:173900.
    PubMed     Abstract available


  48. GONCALVES WA, Ferreira RCM, Rezende BM, Mahecha GAB, et al
    Endogenous opioid and cannabinoid systems modulate the muscle pain: a pharmacological study into the peripheral site.
    Eur J Pharmacol. 2021 Apr 4:174089. doi: 10.1016/j.ejphar.2021.174089.
    PubMed     Abstract available


    March 2021
  49. XU Q, Sun L, Zhang W, Wu H, et al
    A novel visceral pain model of uterine cervix inflammation in rat.
    Eur J Pharmacol. 2021;900:174080.
    PubMed     Abstract available


  50. SHEIKHOLESLAMI MA, Ghafghazi S, Parvardeh S, Koohsari S, et al
    Analgesic effects of cuminic alcohol (4-isopropylbenzyl alcohol), a monocyclic terpenoid, in animal models of nociceptive and neuropathic pain: Role of opioid receptors, L-arginine/NO/cGMP pathway, and inflammatory cytokines.
    Eur J Pharmacol. 2021;900:174075.
    PubMed     Abstract available


  51. DAI G, Li B, Xu Y, Li Z, et al
    Synergistic interaction between matrine and paracetamol in the acetic acid writhing test in mice.
    Eur J Pharmacol. 2021;895:173869.
    PubMed     Abstract available


    February 2021
  52. MENA-VALDES LC, Blanco-Hernandez Y, Espinosa-Juarez JV, Lopez-Munoz FJ, et al
    Haloperidol potentiates antinociceptive effects of morphine and disrupt opioid tolerance.
    Eur J Pharmacol. 2021;893:173825.
    PubMed     Abstract available


  53. ALIJANPOUR S, Jafaripour S, Ghasemzadeh Z, Khakpai F, et al
    Harmaline potentiates morphine-induced antinociception via affecting the ventral hippocampal GABA-A receptors in mice.
    Eur J Pharmacol. 2021;893:173806.
    PubMed     Abstract available


    January 2021
  54. RICARDO CARVALHO VP, Figueira da Silva J, Buzelin MA, Antonio da Silva Junior C, et al
    Calcium channels blockers toxins attenuate abdominal hyperalgesia and inflammatory response associated with the cerulein-induced acute pancreatitis in rats.
    Eur J Pharmacol. 2021;891:173672.
    PubMed     Abstract available


  55. DECIGA-CAMPOS M, Villafan-Gutierrez R, Espinosa-Juarez JV, Jaramillo-Morales OA, et al
    Synergistic interaction between haloperidol and gabapentin in a model of neuropathic nociception in rat.
    Eur J Pharmacol. 2021;891:173702.
    PubMed     Abstract available


  56. CAMARGO LL, Denadai-Souza A, Yshii LM, Lima C, et al
    The potential anti-inflammatory and anti-nociceptive effects of rat hemopressin (PVNFKFLSH) in experimental arthritis.
    Eur J Pharmacol. 2021;890:173636.
    PubMed     Abstract available


    September 2020
  57. NOZU T, Miyagishi S, Ishioh M, Takakusaki K, et al
    Imipramine improves visceral sensation and gut barrier in rat models of irritable bowel syndrome.
    Eur J Pharmacol. 2020;887:173565.
    PubMed     Abstract available


  58. KUBACKA M, Rapacz A, Salat K, Filipek B, et al
    KM-416, a novel phenoxyalkylaminoalkanol derivative with anticonvulsant properties exerts analgesic, local anesthetic, and antidepressant-like activities. Pharmacodynamic, pharmacokinetic, and forced degradation studies.
    Eur J Pharmacol. 2020 Sep 4:173540. doi: 10.1016/j.ejphar.2020.173540.
    PubMed     Abstract available


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