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  Obstructive Lung Diseases

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Articles published in Am J Respir Crit Care Med

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Single Articles


    September 2017
  1. DEN DEKKER HT, Jaddoe VWV, Reiss IK, de Jongste JC, et al
    Fetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study.
    Am J Respir Crit Care Med. 2017 Sep 20. doi: 10.1164/rccm.201703-0631.
    PubMed     Text format     Abstract available


  2. CRINER G
    More Options for Treating Severe Hyperinflation in Advanced Emphysema.
    Am J Respir Crit Care Med. 2017 Sep 19. doi: 10.1164/rccm.201709-1799.
    PubMed     Text format    


  3. GAUVREAU GM, Sehmi R
    Mepolizumab Attenuates Airway Eosinophil Numbers, but Not Their Functional Phenotype in Asthma.
    Am J Respir Crit Care Med. 2017 Sep 19. doi: 10.1164/rccm.201709-1848.
    PubMed     Text format    


  4. MUKHERJEE M, Aleman Paramo F, Kjarsgaard M, Salter B, et al
    Weight-adjusted Intravenous Reslizumab in Severe Asthma with Inadequate Response to Fixed-dose Subcutaneous Mepolizumab.
    Am J Respir Crit Care Med. 2017 Sep 15. doi: 10.1164/rccm.201707-1323.
    PubMed     Text format     Abstract available


  5. CARR TF, Zeki AA, Kraft M
    Eosinophilic and Non-Eosinophilic Asthma.
    Am J Respir Crit Care Med. 2017 Sep 14. doi: 10.1164/rccm.201611-2232.
    PubMed     Text format     Abstract available


  6. KEMP SV, Slebos DJ, Kirk A, Kornaszewska M, et al
    A Multicenter RCT of Zephyr(R) Endobronchial Valve Treatment in Heterogeneous Emphysema (TRANSFORM).
    Am J Respir Crit Care Med. 2017 Sep 8. doi: 10.1164/rccm.201707-1327.
    PubMed     Text format     Abstract available


  7. BARALDO S, Contoli M, Bonato M, Snijders D, et al
    A Deficient Immune Response to Viral Infections in Children Predicts Later Asthma Persistence.
    Am J Respir Crit Care Med. 2017 Sep 1. doi: 10.1164/rccm.201706-1249.
    PubMed     Text format    


  8. KELLY EA, Esnault S, Liu LY, Evans MD, et al
    Mepolizumab Attenuates Airway Eosinophil Numbers, but Not Their Functional Phenotype in Asthma.
    Am J Respir Crit Care Med. 2017 Sep 1. doi: 10.1164/rccm.201611-2234.
    PubMed     Text format     Abstract available


  9. BHATT SP, Bodduluri S, Hoffman EA, Newell JD Jr, et al
    Computed Tomography Measure of Lung at Risk and Lung Function Decline in Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2017;196:569-576.
    PubMed     Text format     Abstract available


    August 2017
  10. LIPSON DA, Barnacle H, Birk R, Brealey N, et al
    FULFIL Trial: Once-Daily Triple Therapy for Patients with Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2017;196:438-446.
    PubMed     Text format     Abstract available


  11. YANG J, Zuo WL, Fukui T, Chao I, et al
    Smoking-Dependent Distal-to-Proximal Repatterning of the Adult Human Small Airway Epithelium.
    Am J Respir Crit Care Med. 2017;196:340-352.
    PubMed     Text format     Abstract available


  12. TEJERO E, Prats E, Casitas R, Galera R, et al
    Classification of Airflow Limitation Based on z-Score Underestimates Mortality in Patients with Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2017;196:298-305.
    PubMed     Text format     Abstract available


  13. AARON SD, Tan WC, Bourbeau J, Sin DD, et al
    Diagnostic Instability and Reversals of Chronic Obstructive Pulmonary Disease Diagnosis in Individuals with Mild to Moderate Airflow Obstruction.
    Am J Respir Crit Care Med. 2017;196:306-314.
    PubMed     Text format     Abstract available


    July 2017
  14. MCEVOY CT, Park BS, Spindel ER
    Sensitive Windows for In Utero Exposures and Asthma Development: Layers of Complexity.
    Am J Respir Crit Care Med. 2017 Jul 20. doi: 10.1164/rccm.201707-1383.
    PubMed     Text format    


  15. PLATTS-MILLS TAE, Woodfolk JA
    Mite Avoidance as a Logical Treatment for Severe Asthma in Childhood. Why Not?
    Am J Respir Crit Care Med. 2017;196:119-121.
    PubMed     Text format    


  16. SKRONSKA-WASEK W, Mutze K, Baarsma HA, Bracke KR, et al
    Reduced Frizzled Receptor 4 Expression Prevents WNT/beta-Catenin-driven Alveolar Lung Repair in Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2017;196:172-185.
    PubMed     Text format     Abstract available


  17. ADLER D, Pepin JL, Dupuis-Lozeron E, Espa-Cervena K, et al
    Comorbidities and Subgroups of Patients Surviving Severe Acute Hypercapnic Respiratory Failure in the Intensive Care Unit.
    Am J Respir Crit Care Med. 2017;196:200-207.
    PubMed     Text format     Abstract available


  18. BEEH KM, Burgel PR, Franssen FME, Lopez-Campos JL, et al
    How Do Dual Long-Acting Bronchodilators Prevent Exacerbations of Chronic Obstructive Pulmonary Disease?
    Am J Respir Crit Care Med. 2017;196:139-149.
    PubMed     Text format     Abstract available


  19. OLIVERIA JP, Salter BM, MacLean J, Kotwal S, et al
    Increased IgE+ B Cells in Sputum, but Not Blood, Bone Marrow, or Tonsils, after Inhaled Allergen Challenge in Subjects with Asthma.
    Am J Respir Crit Care Med. 2017;196:107-109.
    PubMed     Text format    


  20. MOCHIZUKI H, Kusuda S, Okada K, Yoshihara S, et al
    Palivizumab Prophylaxis in Preterm Infants and Subsequent Recurrent Wheezing. Six-Year Follow-up Study.
    Am J Respir Crit Care Med. 2017;196:29-38.
    PubMed     Text format     Abstract available


  21. RINNE ST, Castaneda J, Lindenauer PK, Cleary PD, et al
    Chronic Obstructive Pulmonary Disease Readmissions and Other Measures of Hospital Quality.
    Am J Respir Crit Care Med. 2017;196:47-55.
    PubMed     Text format     Abstract available


    June 2017
  22. BOSE S, Chiu YM, Hsu HL, Di Q, et al
    Prenatal Nitrate Exposure and Childhood Asthma: Influence of Maternal Prenatal Stress and Fetal Sex.
    Am J Respir Crit Care Med. 2017 Jun 29. doi: 10.1164/rccm.201702-0421.
    PubMed     Text format     Abstract available


  23. COTTIN V, Hansell DM, Sverzellati N, Weycker D, et al
    Effect of Emphysema Extent on Serial Lung Function in Patients with Idiopathic Pulmonary Fibrosis.
    Am J Respir Crit Care Med. 2017 Jun 28. doi: 10.1164/rccm.201612-2492.
    PubMed     Text format     Abstract available


  24. KELLY VJ, Hibbert KA, Kohli P, Kone M, et al
    Hypoxic Pulmonary Vasoconstriction Does Not Explain All Regional Perfusion Redistribution in Asthma.
    Am J Respir Crit Care Med. 2017 Jun 23. doi: 10.1164/rccm.201612-2438.
    PubMed     Text format     Abstract available


  25. SAGLANI S, Bush A
    Asthma Attacks in Children: Does Blocking IgE Reduce Rhinoviral Infections?
    Am J Respir Crit Care Med. 2017 Jun 22. doi: 10.1164/rccm.201706-1165.
    PubMed     Text format    


  26. WOODRUFF PG, van den Berge M, Boucher RC, Brightling C, et al
    ATS-NHLBI Asthma COPD Overlap (ACO) Workshop Report.
    Am J Respir Crit Care Med. 2017 Jun 21. doi: 10.1164/rccm.201705-0973.
    PubMed     Text format     Abstract available


  27. PARR DG
    Quantifying the 'Lung at Risk' in COPD: Does Emphysema Beget Emphysema?
    Am J Respir Crit Care Med. 2017 Jun 13. doi: 10.1164/rccm.201705-0962.
    PubMed     Text format    


  28. ESQUIVEL A, Busse WW, Calatroni A, Togias AG, et al
    Effects of Omalizumab on Rhinovirus Infections, Illnesses and Exacerbations of Asthma.
    Am J Respir Crit Care Med. 2017 Jun 13. doi: 10.1164/rccm.201701-0120.
    PubMed     Text format     Abstract available


  29. JONES AC, Bosco A
    Using Network Analysis to Understand Severe Asthma Phenotypes.
    Am J Respir Crit Care Med. 2017;195:1409-1411.
    PubMed     Text format    


  30. POLVERINO F, Laucho-Contreras ME, Petersen H, Bijol V, et al
    A Pilot Study Linking Endothelial Injury in Lungs and Kidneys in Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2017;195:1464-1476.
    PubMed     Text format     Abstract available


    May 2017
  31. ZEIN JG, Love TE, Erzurum SC
    Asthma is Associated with a Lower Risk of Sepsis and Sepsis Related Mortality.
    Am J Respir Crit Care Med. 2017 May 22. doi: 10.1164/rccm.201608-1583.
    PubMed     Text format    


  32. BEGHE B, Fabbri LM, Contoli M, Papi A, et al
    Update in Asthma 2016.
    Am J Respir Crit Care Med. 2017 May 21. doi: 10.1164/rccm.201702-0318.
    PubMed     Text format    


  33. BRUSSELLE GG, Van Braeckel E
    Sputum Neutrophil Elastase as a Biomarker for Disease Activity in Bronchiectasis.
    Am J Respir Crit Care Med. 2017;195:1289-1291.
    PubMed     Text format    


  34. ALTMAN MC, Busse WW
    A Deep Dive into Asthma Transcriptomics. Lessons from U-BIOPRED.
    Am J Respir Crit Care Med. 2017;195:1279-1280.
    PubMed     Text format    


  35. NOLAN CM, Maddocks M, Canavan JL, Jones SE, et al
    Pedometer Step Count Targets during Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease. A Randomized Controlled Trial.
    Am J Respir Crit Care Med. 2017;195:1344-1352.
    PubMed     Text format     Abstract available


  36. SULAIMAN I, Cushen B, Greene G, Seheult J, et al
    Objective Assessment of Adherence to Inhalers by Patients with Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2017;195:1333-1343.
    PubMed     Text format     Abstract available


  37. COSMI L, Annunziato F
    ILC2 are the Earliest Recruiters of Eosinophils in Lungs of Allergic Asthmatic Patients.
    Am J Respir Crit Care Med. 2017 May 5. doi: 10.1164/rccm.201704-0799.
    PubMed     Text format    


  38. BEUTHER DA, Krishnan JA
    Finding Asthma: Building a Foundation for Care and Discovery.
    Am J Respir Crit Care Med. 2017 May 5. doi: 10.1164/rccm.201704-0840.
    PubMed     Text format     Abstract available


  39. YANG CX, Singh A, Kim YW, Conway EM, et al
    Diagnosis of Western Red Cedar Asthma Using a Blood-based Gene Expression Biomarker Panel.
    Am J Respir Crit Care Med. 2017 May 2. doi: 10.1164/rccm.201608-1740.
    PubMed     Text format     Abstract available


  40. FORNO E
    Asthma and Obesity: The Chicken, the Egg, or More Than One Beast?
    Am J Respir Crit Care Med. 2017;195:1124-1125.
    PubMed     Text format    


  41. MARTINEZ FD, Kraft M
    AJRCCM: 100-Year Anniversary. Focus on Asthma in Children and Adults.
    Am J Respir Crit Care Med. 2017;195:1085-1088.
    PubMed     Text format    


  42. KLOOSTER K, Hartman JE, Ten Hacken NHT, Slebos DJ, et al
    Improved Predictors of Survival after Endobronchial Valve Treatment in Patients with Severe Emphysema.
    Am J Respir Crit Care Med. 2017;195:1272-1274.
    PubMed     Text format    


  43. HIND M, Polkey MI, Simonds AK
    AJRCCM: 100-Year Anniversary. Homeward Bound: A Centenary of Home Mechanical Ventilation.
    Am J Respir Crit Care Med. 2017;195:1140-1149.
    PubMed     Text format     Abstract available


  44. ROCHE N, Chapman KR, Vogelmeier CF, Herth FJF, et al
    Blood Eosinophils and Response to Maintenance Chronic Obstructive Pulmonary Disease Treatment. Data from the FLAME Trial.
    Am J Respir Crit Care Med. 2017;195:1189-1197.
    PubMed     Text format     Abstract available


  45. AMARAL AFS, Strachan DP, Burney PGJ, Jarvis DL, et al
    Female Smokers Are at Greater Risk of Airflow Obstruction Than Male Smokers. UK Biobank.
    Am J Respir Crit Care Med. 2017;195:1226-1235.
    PubMed     Text format     Abstract available


    April 2017
  46. CHEN R, Smith SG, Salter B, El-Gammal A, et al
    Allergen-induced Increases in Sputum Levels of Group 2 Innate Lymphoid Cells in Asthmatic Subjects.
    Am J Respir Crit Care Med. 2017 Apr 19. doi: 10.1164/rccm.201612-2427.
    PubMed     Text format     Abstract available



  47. What is Bronchiectasis?
    Am J Respir Crit Care Med. 2017;195:P15-P16.
    PubMed     Text format    


  48. PERZANOWSKI MS, Ono JG, Acosta LM, Kim BI, et al
    Distinct Serum Sphingolipid Profiles among School-aged Children with Exercise-induced Wheeze and Asthma Persistence.
    Am J Respir Crit Care Med. 2017;195:1068-1070.
    PubMed     Text format    


  49. JAMES A
    Airway Remodeling in Asthma: Is it Fixed or Variable?
    Am J Respir Crit Care Med. 2017;195:968-970.
    PubMed     Text format    


  50. FREY U, Bielicki JA
    Fluctuation Metrics as Novel Endpoints for Clinical Trials in Asthma.
    Am J Respir Crit Care Med. 2017;195:967-968.
    PubMed     Text format    


  51. CURTIS JL
    A Hairline Crack in the Levee: Focal Secretory IgA Deficiency as a First Step toward Emphysema.
    Am J Respir Crit Care Med. 2017;195:970-973.
    PubMed     Text format    


  52. MCCONNELL R, Barrington-Trimis JL, Wang K, Urman R, et al
    Electronic Cigarette Use and Respiratory Symptoms in Adolescents.
    Am J Respir Crit Care Med. 2017;195:1043-1049.
    PubMed     Text format     Abstract available


  53. GEBRETSADIK T, Wu P, Carroll KN, Dupont WD, et al
    Preventing RSV:Preventing Asthma - The Missing Link.
    Am J Respir Crit Care Med. 2017 Apr 5. doi: 10.1164/rccm.201702-0380.
    PubMed     Text format    


  54. MOCHIZUKI H, Simoes EA
    Reply to Preventing RSV: Preventing Asthma - The Missing Link.
    Am J Respir Crit Care Med. 2017 Apr 5. doi: 10.1164/rccm.201703-0533.
    PubMed     Text format    


  55. WI CI, Sohn S, Rolfes MC, Seabright A, et al
    Application of a Natural Language Processing Algorithm to Asthma Ascertainment: An Automated Chart Review.
    Am J Respir Crit Care Med. 2017 Apr 4. doi: 10.1164/rccm.201610-2006.
    PubMed     Text format     Abstract available


  56. WELLS TJ, Davison J, Sheehan E, Kanagasundaram S, et al
    The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies.
    Am J Respir Crit Care Med. 2017;195:955-958.
    PubMed     Text format    


  57. MARTINEZ FJ, Vestbo J, Anderson JA, Brook RD, et al
    Effect of Fluticasone Furoate and Vilanterol on Exacerbations of Chronic Obstructive Pulmonary Disease in Patients with Moderate Airflow Obstruction.
    Am J Respir Crit Care Med. 2017;195:881-888.
    PubMed     Text format     Abstract available


  58. JOLLIET P, Ouanes-Besbes L, Abroug F, Ben Khelil J, et al
    A Multicenter Randomized Trial Assessing the Efficacy of Helium/Oxygen in Severe Exacerbations of Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2017;195:871-880.
    PubMed     Text format     Abstract available


    March 2017
  59. BUI DS, Burgess JA, Bui M, Abramson MJ, et al
    Reply to Bias in Association Between FEV1/FVC % Predicted at 7 Years and Asthma-COPD Overlap Syndrome.
    Am J Respir Crit Care Med. 2017 Mar 31. doi: 10.1164/rccm.201703-0534.
    PubMed     Text format    


  60. AYUBI E, Safiri S
    Bias in Association Between FEV1/FVC % Predicted at 7 Years and Asthma-COPD Overlap Syndrome.
    Am J Respir Crit Care Med. 2017 Mar 31. doi: 10.1164/rccm.201702-0370.
    PubMed     Text format    


  61. KEENAN A, Browne W, Bhargava M
    Diffuse Subcutaneous Emphysema Following Tracheal Perforation.
    Am J Respir Crit Care Med. 2017 Mar 17. doi: 10.1164/rccm.201611-2394.
    PubMed     Text format    


  62. YANG IV, Richards A, Davidson EJ, Stevens AD, et al
    The Nasal Methylome: A Key to Understanding Allergic Asthma.
    Am J Respir Crit Care Med. 2017;195:829-831.
    PubMed     Text format    


  63. MARTINEZ FJ, Mannino D, Leidy NK, Malley KG, et al
    A New Approach for Identifying Patients with Undiagnosed Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2017;195:748-756.
    PubMed     Text format     Abstract available


  64. MURRAY CS, Foden P, Sumner H, Shepley E, et al
    Preventing Severe Asthma Exacerbations in Children: A Randomised Trial of Mite Impermeable Bedcovers.
    Am J Respir Crit Care Med. 2017 Mar 10. doi: 10.1164/rccm.201609-1966.
    PubMed     Text format     Abstract available


  65. KIM RY, Pinkerton JW, Essilfie AT, Robertson AA, et al
    Role for NLRP3 Inflammasome-mediated, IL-1beta-dependent Responses in Severe, Steroid-resistant Asthma.
    Am J Respir Crit Care Med. 2017 Mar 2. doi: 10.1164/rccm.201609-1830.
    PubMed     Text format     Abstract available


  66. EGE MJ
    Asthma and Prenatal Inflammation.
    Am J Respir Crit Care Med. 2017;195:546-548.
    PubMed     Text format    


  67. KOPPELMAN GH, Gehring U
    Data-driven Asthma Phenotypes in Childhood. Does the Environment Hold the Clue?
    Am J Respir Crit Care Med. 2017;195:545-546.
    PubMed     Text format    


  68. VOGELMEIER CF, Criner GJ, Martinez FJ, Anzueto A, et al
    Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary.
    Am J Respir Crit Care Med. 2017;195:557-582.
    PubMed     Text format     Abstract available


  69. GUELL MR, Cejudo P, Ortega F, Puy MC, et al
    Benefits of Long-Term Pulmonary Rehabilitation Maintenance Program in Patients with Severe Chronic Obstructive Pulmonary Disease. Three-Year Follow-up.
    Am J Respir Crit Care Med. 2017;195:622-629.
    PubMed     Text format     Abstract available


  70. RAMRATNAM SK, Visness CM, Jaffee KF, Bloomberg GR, et al
    Relationships among Maternal Stress and Depression, Type 2 Responses, and Recurrent Wheezing at Age 3 Years in Low-Income Urban Families.
    Am J Respir Crit Care Med. 2017;195:674-681.
    PubMed     Text format     Abstract available


    February 2017
  71. MODENA BD, Wenzel SE
    Consistency of T2 Gene Signatures in Severe Asthma. Key to Effective Treatments or Merely the Tip of the Iceberg?
    Am J Respir Crit Care Med. 2017;195:411-412.
    PubMed     Text format    


  72. ORTEGA VE, Torgerson DG
    On a Collision Course: The Electronic Medical Record and Genetic Studies of Asthma.
    Am J Respir Crit Care Med. 2017;195:412-414.
    PubMed     Text format    


  73. RADDER JE, Zhang Y, Gregory AD, Yu S, et al
    Extreme Trait Whole Genome Sequencing Identifies PTPRO as a Novel Candidate Gene in Emphysema with Severe Airflow Obstruction.
    Am J Respir Crit Care Med. 2017 Feb 15. doi: 10.1164/rccm.201606-1147.
    PubMed     Text format     Abstract available


  74. KEENE JD, Jacobson S, Kechris K, Kinney GL, et al
    Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts.
    Am J Respir Crit Care Med. 2017;195:473-481.
    PubMed     Text format     Abstract available


  75. MARTINEZ CH, Diaz AA, Meldrum C, Curtis JL, et al
    Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS.
    Am J Respir Crit Care Med. 2017;195:464-472.
    PubMed     Text format     Abstract available


  76. SHANNON VR, Nanda AS, Faiz SA
    Marfan Syndrome Presenting as Giant Bullous Emphysema.
    Am J Respir Crit Care Med. 2017 Feb 10. doi: 10.1164/rccm.201610-2062.
    PubMed     Text format    


  77. BUI DS, Burgess JA, Lowe AJ, Perret JL, et al
    Childhood Lung Function Predicts Adult COPD and Asthma-COPD Overlap Syndrome (ACOS).
    Am J Respir Crit Care Med. 2017 Feb 1. doi: 10.1164/rccm.201606-1272.
    PubMed     Text format     Abstract available


  78. LOYMANS RJ, Sterk PJ
    Exacerbation-Prone Asthma: A Separate Bioclinical Phenotype?
    Am J Respir Crit Care Med. 2017;195:275-277.
    PubMed     Text format    


    January 2017
  79. SHEN ZJ, Hu J, Kashi V, Kelly EA, et al
    Epstein-Barr Virus Induced Gene 2 (EBI2) Mediates Allergen-induced, Leukocyte Migration into Airways.
    Am J Respir Crit Care Med. 2017 Jan 26. doi: 10.1164/rccm.201608-1580.
    PubMed     Text format     Abstract available


  80. CHEN Z, Salam MT, Alderete TL, Habre R, et al
    Effects of Childhood Asthma on the Development of Obesity among School-aged Children.
    Am J Respir Crit Care Med. 2017 Jan 19. doi: 10.1164/rccm.201608-1691.
    PubMed     Text format     Abstract available


  81. GOMEZ JL, Kaminski N
    Toward Precision Medicine of Symptom Control in Asthma.
    Am J Respir Crit Care Med. 2017;195:147-148.
    PubMed     Text format    


  82. GOBBI A, Dellaca RL, King G, Thamrin C, et al
    Toward Predicting Individual Risk in Asthma Using Daily Home Monitoring of Resistance.
    Am J Respir Crit Care Med. 2017;195:265-267.
    PubMed     Text format    


  83. HAN YY, Celedon JC
    Maternal Folate Intake during Pregnancy and Childhood Asthma.
    Am J Respir Crit Care Med. 2017;195:155-156.
    PubMed     Text format    


  84. PRAKASH YS, Halayko AJ, Gosens R, Panettieri RA Jr, et al
    An Official American Thoracic Society Research Statement: Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling.
    Am J Respir Crit Care Med. 2017;195:e4-e19.
    PubMed     Text format     Abstract available


  85. HOUBEN-WILKE S, Jorres RA, Bals R, Franssen FM, et al
    Peripheral Artery Disease and Its Clinical Relevance in Patients with Chronic Obstructive Pulmonary Disease in the COPD and Systemic Consequences-Comorbidities Network Study.
    Am J Respir Crit Care Med. 2017;195:189-197.
    PubMed     Text format     Abstract available


  86. WOOD LG
    Asthma in the Obese: A Big and Growing Problem.
    Am J Respir Crit Care Med. 2017;195:4-5.
    PubMed     Text format    


  87. CONICKX G, Mestdagh P, Avila Cobos F, Verhamme FM, et al
    MicroRNA Profiling Reveals a Role for MicroRNA-218-5p in the Pathogenesis of Chronic Obstructive Pulmonary Disease.
    Am J Respir Crit Care Med. 2017;195:43-56.
    PubMed     Text format     Abstract available


    December 2016
  88. MODENA BD, Bleecker ER, Busse WW, Erzurum SC, et al
    Gene Expression Correlated to Severe Asthma Characteristics Reveals Heterogeneous Mechanisms of Severe Disease.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  89. STEINKE JW
    Can Genes Control Asthmatic Lung Function Patterns?
    Am J Respir Crit Care Med. 2016;194:1439-1440.
    PubMed     Text format    


  90. SLOAN CD, Johnston JD
    Can Extreme Air Pollution Events Provide a Window into Incident Asthma?
    Am J Respir Crit Care Med. 2016;194:1440-1441.
    PubMed     Text format    


  91. KANTOR DB, McDonald MC, Stenquist N, Schultz BJ, et al
    Omalizumab Is Associated with Reduced Acute Severity of Rhinovirus-triggered Asthma Exacerbation.
    Am J Respir Crit Care Med. 2016;194:1552-1555.
    PubMed     Text format    


  92. PETRACHE I, Serban K
    Lost in Trans-IL-6 Signaling: Alveolar Type II Cell Death in Emphysema.
    Am J Respir Crit Care Med. 2016;194:1441-1443.
    PubMed     Text format    


  93. PHIPATANAKUL W, Mauger DT, Sorkness RL, Gaffin JM, et al
    Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  94. NAVEED SU, Clements D, Jackson DJ, Philp C, et al
    MMP-1 Activation Contributes to Airway Smooth Muscle Growth and Asthma Severity.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  95. BIGLER J, Boedigheimer M, Schofield JP, Skipp PJ, et al
    A Severe Asthma Disease Signature from Gene Expression Profiling of Peripheral Blood from U-BIOPRED Cohorts.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  96. GROSS NJ, Barnes PJ
    New Therapies for Asthma and COPD.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  97. CHALMERS JD, Moffitt KL, Suarez-Cuartin G, Sibila O, et al
    Neutrophil Elastase Activity is Associated with Exacerbations and Lung Function Decline in Bronchiectasis.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  98. HYNES G, Pavord ID
    Asthma-like Features and Chronic Obstructive Pulmonary Disease.
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  99. GOODWIN RD
    Toward Improving Our Understanding of the Link between Mental Health, Lung Function, and Asthma Diagnosis. The Challenge of Asthma Measurement.
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    November 2016
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    Fluctuation Analysis of Peak Expiratory Flow and its Association with Treatment Failure in Asthma.
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    The Less Refined Reference Group of "No Asthma" Is Related to the Opposing Interaction Findings.
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  104. HOPKINSON NS
    Endobronchial Valves as a Treatment for Emphysema. Moving out of the Shadow of Lung Volume Reduction Surgery.
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  105. HANCOX RJ, Gray AR, Sears MR
    Reply: The Less Refined Reference Group of "No Asthma" Is Not Related to the Opposing Interaction Findings.
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    October 2016
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    Opportunist Turns Allergen: Double Life of Pneumocystis jirovecii in Asthma.
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    September 2016
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    Asthma Trajectories in a Population-based Birth Cohort: Impacts of Air Pollution and Greenness.
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    August 2016
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    Post-traumatic Stress Disorder, Bronchodilator Response, and Incident Asthma in World Trade Center Rescue and Recovery Workers.
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  120. KUNZLI N
    Does Air Pollution Cause a Threefold Increase in Chronic Obstructive Pulmonary Disease among Patients with Asthma?
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    Does Age of Onset of Asthma Influence the Effect of Cigarette Smoking on Lung Function?
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    July 2016
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    Small Airway Disease or Emphysema: Which Is More Important in Lung Function and FEV1 Decline? An Old Story with a New Twist.
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    IFN Deficiency in Asthma Attacks. Is Restoring Toll-like Receptor-7 Expression a New Treatment Approach in Severe Asthma?
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    June 2016
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    May 2016
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    April 2016
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    Sex Differences in Chronic Obstructive Pulmonary Disease Mechanisms.
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    Chronic Obstructive Pulmonary Disease: When Pulmonologists Do Something Good for the Heart.
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  143. STONE IS, Barnes NC, James WY, Midwinter D, et al
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    March 2016
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  146. HILLAS G, Perlikos F, Toumpanakis D, Litsiou E, et al
    Controlled Mechanical Ventilation Attenuates the Systemic Inflammation of Severe Chronic Obstructive Pulmonary Disease Exacerbations.
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  147. MILLER BE, Tal-Singer R, Rennard SI, Furtwaengler A, et al
    Plasma Fibrinogen Qualification as a Drug Development Tool in Chronic Obstructive Pulmonary Disease. Perspective of the Chronic Obstructive Pulmonary Disease Biomarker Qualification Consortium.
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    Biofilm Formation by Mycobacterium abscessus in a Lung Cavity.
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  149. ALLINSON JP, Hardy R, Donaldson GC, Shaheen SO, et al
    The Presence of Chronic Mucus Hypersecretion across Adult Life in Relation to Chronic Obstructive Pulmonary Disease Development.
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  150. IYER KS, Newell JD Jr, Jin D, Fuld MK, et al
    Quantitative Dual-Energy Computed Tomography Supports a Vascular Etiology of Smoking-induced Inflammatory Lung Disease.
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  151. MCKENDRY RT, Spalluto CM, Burke H, Nicholas B, et al
    Dysregulation of Antiviral Function of CD8(+) T Cells in the Chronic Obstructive Pulmonary Disease Lung. Role of the PD-1-PD-L1 Axis.
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  153. CURTIS JL
    At the Checkpoint: Lung CD8(+) T Cells, Respiratory Viruses, and Chronic Obstructive Pulmonary Disease.
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  154. HURST JR
    Precision Medicine in Chronic Obstructive Pulmonary Disease.
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  155. SPINDEL ER, McEvoy CT
    The Role of Nicotine in the Effects of Maternal Smoking during Pregnancy on Lung Development and Childhood Respiratory Disease. Implications for Dangers of E-Cigarettes.
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    Hypoxic Gene Expression of Donor Bronchi Linked to Airway Complications after Lung Transplantation.
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    February 2016
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    Making Precision Medicine Socially Precise. Take a Deep Breath.
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  158. TAUBE C, Hiemstra PS
    IL-13 and the Airway Epithelium. It Is All in the Genes.
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    Bridging Lung Development with Chronic Obstructive Pulmonary Disease. Relevance of Developmental Pathways in Chronic Obstructive Pulmonary Disease Pathogenesis.
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    Pulmonary Disease and Age at Immigration among Hispanics. Results from the Hispanic Community Health Study/Study of Latinos.
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    Dyspnea Intensity: A Patient-reported Measure of Respiratory Drive and Disease Severity.
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  162. LEUNG JM, Sin DD
    Chronic Obstructive Pulmonary Disease and Stroke. Strange Bedfellows.
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  163. HART JL, Pflug E, Madden V, Halpern SD, et al
    Thinking Forward: Future-oriented Thinking among Patients with Tobacco-associated Thoracic Diseases and Their Surrogates.
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    Common Mechanisms of Dyspnea in Chronic Interstitial and Obstructive Lung Disorders.
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    January 2016
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    Is the Road to Precision Medicine in Chronic Lung Disease Paved with Degraded Chitin?
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    Restoration of Corticosteroid Sensitivity in Chronic Obstructive Pulmonary Disease by Inhibition of Mammalian Target of Rapamycin.
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    Results of the Randomized Danish Lung Cancer Screening Trial with Focus on High-risk Profiling.
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