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Articles published in Proc Natl Acad Sci U S A

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    April 2014
  1. CANAAN A, Defuria J, Perelman E, Schultz V, et al
    Extended lifespan and reduced adiposity in mice lacking the FAT10 gene.
    Proc Natl Acad Sci U S A. 2014;111:5313-8.
    PubMed     Text format     Related articles    Abstract available


    February 2014

  2. Correction for Chatzigeorgiou et al., Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
    Proc Natl Acad Sci U S A. 2014.
    PubMed     Text format     Related articles   


  3. CHATZIGEORGIOU A, Seijkens T, Zarzycka B, Engel D, et al
    Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
    Proc Natl Acad Sci U S A. 2014.
    PubMed     Text format     Related articles    Abstract available


    January 2014
  4. FREDERICK CB, Snellman K, Putnam RD
    Increasing socioeconomic disparities in adolescent obesity.
    Proc Natl Acad Sci U S A. 2014;111:1338-42.
    PubMed     Text format     Related articles    Abstract available


    December 2013
  5. CHA JY, Kim HJ, Yu JH, Xu J, et al
    Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


    November 2013
  6. LIU J, Cinar R, Xiong K, Godlewski G, et al
    Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase.
    Proc Natl Acad Sci U S A. 2013;110:18832-7.
    PubMed     Text format     Related articles    Abstract available


  7. WANG F, Mullican SE, DiSpirito JR, Peed LC, et al
    Lipoatrophy and severe metabolic disturbance in mice with fat-specific deletion of PPARgamma.
    Proc Natl Acad Sci U S A. 2013;110:18656-61.
    PubMed     Text format     Related articles    Abstract available


    October 2013
  8. SHIRAZI R, Palsdottir V, Collander J, Anesten F, et al
    Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6.
    Proc Natl Acad Sci U S A. 2013;110:16199-204.
    PubMed     Text format     Related articles    Abstract available


    August 2013
  9. GOLDLUST IS , Hermetz KE, Catalano LM, Barfield RT, et al
    Mouse model implicates GNB3 duplication in a childhood obesity syndrome.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


  10. POWELL WT, Coulson RL, Gonzales ML, Crary FK, et al
    R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.
    Proc Natl Acad Sci U S A. 2013;110:13938-43.
    PubMed     Text format     Related articles    Abstract available


  11. PATTI ME
    Reducing maternal weight improves offspring metabolism and alters (or modulates) methylation.
    Proc Natl Acad Sci U S A. 2013;110:12859-60.
    PubMed     Text format     Related articles   


  12. RUBIN H
    Promotion and selection by serum growth factors drive field cancerization, which is anticipated in vivo by type 2 diabetes and obesity.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


    July 2013
  13. PRICEMAN SJ , Kujawski M, Shen S, Cherryholmes GA, et al
    Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


  14. LEE KY , Yamamoto Y, Boucher J, Winnay JN, et al
    Shox2 is a molecular determinant of depot-specific adipocyte function.
    Proc Natl Acad Sci U S A. 2013;110:11409-14.
    PubMed     Text format     Related articles    Abstract available


  15. GUENARD F , Deshaies Y, Cianflone K, Kral JG, et al
    Differential methylation in glucoregulatory genes of offspring born before vs. after maternal gastrointestinal bypass surgery.
    Proc Natl Acad Sci U S A. 2013;110:11439-44.
    PubMed     Text format     Related articles    Abstract available


    June 2013
  16. CONE RD
    QnAs with Roger D. Cone.
    Proc Natl Acad Sci U S A. 2013;110:9618.
    PubMed     Text format     Related articles   


  17. XU P , Grueter BA, Britt JK, McDaniel L, et al
    Double deletion of melanocortin 4 receptors and SAPAP3 corrects compulsive behavior and obesity in mice.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


    May 2013
  18. UPADHYAY SK , Eckel-Mahan KL, Mirbolooki MR, Tjong I, et al
    Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


  19. ALPAR A , Harkany T
    Orexin neurons use endocannabinoids to break obesity-induced inhibition.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles   


  20. WILLIAMS SC
    Link between obesity and cancer.
    Proc Natl Acad Sci U S A. 2013;110:8753-4.
    PubMed     Text format     Related articles   


  21. AOUADI M , Tencerova M, Vangala P, Yawe JC, et al
    Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice.
    Proc Natl Acad Sci U S A. 2013;110:8278-83.
    PubMed     Text format     Related articles    Abstract available


  22. EVERARD A , Belzer C, Geurts L, Ouwerkerk JP, et al
    Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


    April 2013
  23. CRISTINO L , Busetto G, Imperatore R, Ferrandino I, et al
    Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


  24. PANARO BL , Cone RD
    Melanocortin-4 receptor mutations paradoxically reduce preference for palatable foods.
    Proc Natl Acad Sci U S A. 2013;110:7050-5.
    PubMed     Text format     Related articles    Abstract available


  25. BERBARI NF , Pasek RC, Malarkey EB, Yazdi SM, et al
    Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


    March 2013
  26. DEFURIA J , Belkina AC, Jagannathan-Bogdan M, Snyder-Cappione J, et al
    B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


    February 2013

  27. Correction for Millership et al., Increased lipolysis and altered lipid homeostasis protect gamma-synuclein-null mutant mice from diet-induced obesity.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles   


    January 2013
  28. GULATI P , Cheung MK, Antrobus R, Church CD, et al
    Role for the obesity-related FTO gene in the cellular sensing of amino acids.
    Proc Natl Acad Sci U S A. 2013.
    PubMed     Text format     Related articles    Abstract available


  29. MITRA MS , Chen Z, Ren H, Harris TE, et al
    Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation.
    Proc Natl Acad Sci U S A. 2013;110:642-7.
    PubMed     Text format     Related articles    Abstract available


    December 2012
  30. KANTOMAA MT , Stamatakis E, Kankaanpaa A, Kaakinen M, et al
    Physical activity and obesity mediate the association between childhood motor function and adolescents' academic achievement.
    Proc Natl Acad Sci U S A. 2012.
    PubMed     Text format     Related articles    Abstract available


  31. MILLERSHIP S , Ninkina N, Guschina IA, Norton J, et al
    Increased lipolysis and altered lipid homeostasis protect gamma-synuclein-null mutant mice from diet-induced obesity.
    Proc Natl Acad Sci U S A. 2012.
    PubMed     Text format     Related articles    Abstract available


    October 2012
  32. FRAKER PJ
    Profile of Pamela J. Fraker. Interview by Tinsley H. Davis.
    Proc Natl Acad Sci U S A. 2012;109:16754-5.
    PubMed     Text format     Related articles   


    September 2012
  33. CARRER M , Liu N, Grueter CE, Williams AH, et al
    Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378*.
    Proc Natl Acad Sci U S A. 2012;109:15330-5.
    PubMed     Text format     Related articles    Abstract available


  34. FU T , Choi SE, Kim DH, Seok S, et al
    Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor beta-Klotho.
    Proc Natl Acad Sci U S A. 2012.
    PubMed     Text format     Related articles    Abstract available


    May 2012
  35. TROTTIER MD , Naaz A, Li Y, Fraker PJ, et al
    Enhancement of hematopoiesis and lymphopoiesis in diet-induced obese mice.
    Proc Natl Acad Sci U S A. 2012;109:7622-9.
    PubMed     Text format     Related articles    Abstract available


  36. RABINOVITZ S , Kaufman Y, Ludwig G, Razin A, et al
    Mechanisms of activation of the paternally expressed genes by the Prader-Willi imprinting center in the Prader-Willi/Angelman syndromes domains.
    Proc Natl Acad Sci U S A. 2012;109:7403-8.
    PubMed     Text format     Related articles    Abstract available


  37. WEIDNER C , de Groot JC, Prasad A, Freiwald A, et al
    Amorfrutins are potent antidiabetic dietary natural products.
    Proc Natl Acad Sci U S A. 2012;109:7257-62.
    PubMed     Text format     Related articles    Abstract available


  38. WU L , Parekh VV, Gabriel CL, Bracy DP, et al
    Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice.
    Proc Natl Acad Sci U S A. 2012;109:E1143-52.
    PubMed     Text format     Related articles    Abstract available


    April 2012
  39. KODAMA K , Horikoshi M, Toda K, Yamada S, et al
    Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes.
    Proc Natl Acad Sci U S A. 2012.
    PubMed     Text format     Related articles    Abstract available


    March 2012
  40. ZHANG Y , Li Y, Niepel MW, Kawano Y, et al
    Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance.
    Proc Natl Acad Sci U S A. 2012.
    PubMed     Text format     Related articles    Abstract available


    February 2012
  41. DUBOSE AJ , Smith EY, Johnstone KA, Resnick JL, et al
    Temporal and developmental requirements for the Prader-Willi imprinting center.
    Proc Natl Acad Sci U S A. 2012;109:3446-50.
    PubMed     Text format     Related articles    Abstract available


  42. WU Q , Whiddon BB, Palmiter RD
    Ablation of neurons expressing agouti-related protein, but not melanin concentrating hormone, in leptin-deficient mice restores metabolic functions and fertility.
    Proc Natl Acad Sci U S A. 2012;109:3155-60.
    PubMed     Text format     Related articles    Abstract available


    December 2011
  43. FELDMAN DE , Chen C, Punj V, Tsukamoto H, et al
    Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells.
    Proc Natl Acad Sci U S A. 2011.
    PubMed     Text format     Related articles    Abstract available


  44. GREENBLUM S , Turnbaugh PJ, Borenstein E
    Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease.
    Proc Natl Acad Sci U S A. 2011.
    PubMed     Text format     Related articles    Abstract available


    November 2011
  45. STAQUICINI FI , Cardo-Vila M, Kolonin MG, Trepel M, et al
    Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients.
    Proc Natl Acad Sci U S A. 2011;108:18637-42.
    PubMed     Text format     Related articles    Abstract available


    October 2011
  46. YANG RY , Yu L, Graham JL, Hsu DK, et al
    Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice.
    Proc Natl Acad Sci U S A. 2011.
    PubMed     Text format     Related articles    Abstract available


    September 2011
  47. BECATTINI B , Marone R, Zani F, Arsenijevic D, et al
    PI3K{gamma} within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance.
    Proc Natl Acad Sci U S A. 2011.
    PubMed     Text format     Related articles    Abstract available


  48. MAO T , Shao M, Qiu Y, Huang J, et al
    PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism.
    Proc Natl Acad Sci U S A. 2011;108:15852-7.
    PubMed     Text format     Related articles    Abstract available


  49. HANLON EC , Van Cauter E
    Quantification of sleep behavior and of its impact on the cross-talk between the brain and peripheral metabolism.
    Proc Natl Acad Sci U S A. 2011;108 Suppl 3:15609-16.
    PubMed     Text format     Related articles    Abstract available


    August 2011
  50. STIENSTRA R , van Diepen JA, Tack CJ, Zaki MH, et al
    Inflammasome is a central player in the induction of obesity and insulin resistance.
    Proc Natl Acad Sci U S A. 2011.
    PubMed     Text format     Related articles    Abstract available


    July 2011
  51. KUROKAWA J , Nagano H, Ohara O, Kubota N, et al
    Apoptosis inhibitor of macrophage (AIM) is required for obesity-associated recruitment of inflammatory macrophages into adipose tissue.
    Proc Natl Acad Sci U S A. 2011.
    PubMed     Text format     Related articles    Abstract available


    May 2011
  52. LURIA A , Bettaieb A, Xi Y, Shieh GJ, et al
    Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance.
    Proc Natl Acad Sci U S A. 2011;108:9038-43.
    PubMed     Text format     Related articles    Abstract available


    March 2011
  53. KOBAYASHI N , Ueki K, Okazaki Y, Iwane A, et al
    Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance.
    Proc Natl Acad Sci U S A. 2011.
    PubMed     Text format     Related articles    Abstract available


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