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  Obesity

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Articles published in Proc Natl Acad Sci U S A

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    June 2016
  1. CHEN L, Chen Q, Xie B, Quan C, et al
    Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion.
    Proc Natl Acad Sci U S A. 2016 Jun 15. pii: 201600581.
    PubMed     Text format     Abstract available


    May 2016
  2. XUE Y, Xu X, Zhang XQ, Farokhzad OC, et al
    Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles.
    Proc Natl Acad Sci U S A. 2016 May 2. pii: 201603840.
    PubMed     Text format     Abstract available


    April 2016
  3. MORELLO G, Imperatore R, Palomba L, Finelli C, et al
    Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling.
    Proc Natl Acad Sci U S A. 2016 Apr 11. pii: 201521304.
    PubMed     Text format     Abstract available


    January 2016
  4. AYE IL, Rosario FJ, Powell TL, Jansson T, et al
    Reply to Carbillon: Fetal/placental weight ratio and placental function.
    Proc Natl Acad Sci U S A. 2016;113:E261.
    PubMed     Text format    


  5. CARBILLON L
    Fetal/placental weight ratio in a mouse model of maternal diet-induced obesity.
    Proc Natl Acad Sci U S A. 2016 Jan 11. pii: 201521107.
    PubMed     Text format    


  6. STOKES A, Preston SH
    Revealing the burden of obesity using weight histories.
    Proc Natl Acad Sci U S A. 2016 Jan 4. pii: 201515472.
    PubMed     Text format     Abstract available


    December 2015
  7. NEWMAN AB
    Is the onset of obesity the same as aging?
    Proc Natl Acad Sci U S A. 2015 Dec 16. pii: 201515367.
    PubMed     Text format    


  8. BELSKY DW
    Reply to Newman: Quantification of biological aging in young adults is not the same thing as the onset of obesity.
    Proc Natl Acad Sci U S A. 2015 Dec 16. pii: 201518878.
    PubMed     Text format    


  9. ZHENG C, Yang Q, Xu C, Shou P, et al
    CD11b regulates obesity-induced insulin resistance via limiting alternative activation and proliferation of adipose tissue macrophages.
    Proc Natl Acad Sci U S A. 2015 Dec 15. pii: 201500396.
    PubMed     Text format     Abstract available


  10. BOCARSLY ME, Fasolino M, Kane GA, LaMarca EA, et al
    Obesity diminishes synaptic markers, alters microglial morphology, and impairs cognitive function.
    Proc Natl Acad Sci U S A. 2015 Dec 7. pii: 201511593.
    PubMed     Text format     Abstract available


    October 2015
  11. FONSECA TL, Fernandes GW, McAninch EA, Bocco BM, et al
    Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.
    Proc Natl Acad Sci U S A. 2015 Oct 27. pii: 201508943.
    PubMed     Text format     Abstract available


  12. SCHREIBER R, Hofer P, Taschler U, Voshol PJ, et al
    Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity.
    Proc Natl Acad Sci U S A. 2015 Oct 27. pii: 201516004.
    PubMed     Text format     Abstract available


    September 2015
  13. AYE IL, Rosario FJ, Powell TL, Jansson T, et al
    Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth.
    Proc Natl Acad Sci U S A. 2015 Sep 28. pii: 201515484.
    PubMed     Text format     Abstract available


    August 2015
  14. DATTA P, Allamargot C, Hudson JS, Andersen EK, et al
    Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
    Proc Natl Acad Sci U S A. 2015;112:E4400-9.
    PubMed     Text format     Abstract available


    July 2015
  15. DIEHL KL, Ivy MA, Rabidoux S, Petry SM, et al
    Differential sensing for the regio- and stereoselective identification and quantitation of glycerides.
    Proc Natl Acad Sci U S A. 2015;112:E3977-86.
    PubMed     Text format     Abstract available


  16. ZENG W, Lu YH, Lee J, Friedman JM, et al
    Reanalysis of parabiosis of obesity mutants in the age of leptin.
    Proc Natl Acad Sci U S A. 2015 Jul 6. pii: 201510378.
    PubMed     Text format     Abstract available


    June 2015
  17. LEWIS MW, Brant JO, Kramer JM, Moss JI, et al
    Angelman syndrome imprinting center encodes a transcriptional promoter.
    Proc Natl Acad Sci U S A. 2015;112:6871-5.
    PubMed     Text format     Abstract available


    May 2015
  18. KOOIJMAN S, van den Berg R, Ramkisoensing A, Boon MR, et al
    Prolonged daily light exposure increases body fat mass through attenuation of brown adipose tissue activity.
    Proc Natl Acad Sci U S A. 2015;112:6748-53.
    PubMed     Text format     Abstract available


    April 2015
  19. SEKIMOTO R, Fukuda S, Maeda N, Tsushima Y, et al
    Visualized macrophage dynamics and significance of S100A8 in obese fat.
    Proc Natl Acad Sci U S A. 2015;112:E2058-66.
    PubMed     Text format     Abstract available


  20. MINCHIN JE, Dahlman I, Harvey CJ, Mejhert N, et al
    Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue.
    Proc Natl Acad Sci U S A. 2015;112:4363-8.
    PubMed     Text format     Abstract available


    March 2015
  21. NASIF S, de Souza FS, Gonzalez LE, Yamashita M, et al
    Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood.
    Proc Natl Acad Sci U S A. 2015 Mar 30. pii: 201500672.
    PubMed     Text format     Abstract available


    January 2015
  22. CIPOLLETTA D, Cohen P, Spiegelman BM, Benoist C, et al
    Appearance and disappearance of the mRNA signature characteristic of Treg cells in visceral adipose tissue: age, diet, and PPARgamma effects.
    Proc Natl Acad Sci U S A. 2015;112:482-7.
    PubMed     Text format     Abstract available


  23. LOPEZ-VICARIO C, Alcaraz-Quiles J, Garcia-Alonso V, Rius B, et al
    Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides.
    Proc Natl Acad Sci U S A. 2015;112:536-41.
    PubMed     Text format     Abstract available


  24. ROSENQUIST JN, Lehrer SF, O'Malley AJ, Zaslavsky AM, et al
    Cohort of birth modifies the association between FTO genotype and BMI.
    Proc Natl Acad Sci U S A. 2015;112:354-9.
    PubMed     Text format     Abstract available


  25. BOWLES NP, Karatsoreos IN, Li X, Vemuri VK, et al
    A peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome.
    Proc Natl Acad Sci U S A. 2015;112:285-90.
    PubMed     Text format     Abstract available


    December 2014
  26. PAZ JC, Park S, Phillips N, Matsumura S, et al
    Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation.
    Proc Natl Acad Sci U S A. 2014;111:17116-21.
    PubMed     Text format     Abstract available


  27. MCHILL AW, Melanson EL, Higgins J, Connick E, et al
    Impact of circadian misalignment on energy metabolism during simulated nightshift work.
    Proc Natl Acad Sci U S A. 2014;111:17302-7.
    PubMed     Text format     Abstract available


    October 2014
  28. HONEK J, Seki T, Iwamoto H, Fischer C, et al
    Modulation of age-related insulin sensitivity by VEGF-dependent vascular plasticity in adipose tissues.
    Proc Natl Acad Sci U S A. 2014;111:14906-11.
    PubMed     Text format     Abstract available


  29. HORVATH S, Erhart W, Brosch M, Ammerpohl O, et al
    Obesity accelerates epigenetic aging of human liver.
    Proc Natl Acad Sci U S A. 2014 Oct 13. pii: 201412759.
    PubMed     Text format     Abstract available


  30. WU L, Parekh VV, Hsiao J, Kitamura D, et al
    Spleen supports a pool of innate-like B cells in white adipose tissue that protects against obesity-associated insulin resistance.
    Proc Natl Acad Sci U S A. 2014 Oct 13. pii: 201324052.
    PubMed     Text format     Abstract available


  31. TAJAN M, Batut A, Cadoudal T, Deleruyelle S, et al
    LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity.
    Proc Natl Acad Sci U S A. 2014 Oct 6. pii: 201406107.
    PubMed     Text format     Abstract available


    September 2014
  32. MA X, Xu L, Gavrilova O, Mueller E, et al
    Role of forkhead box protein A3 in age-associated metabolic decline.
    Proc Natl Acad Sci U S A. 2014;111:14289-94.
    PubMed     Text format     Abstract available


    July 2014
  33. LEE JH, Bassel-Duby R, Olson EN
    Heart- and muscle-derived signaling system dependent on MED13 and Wingless controls obesity in Drosophila.
    Proc Natl Acad Sci U S A. 2014;111:9491-6.
    PubMed     Text format     Abstract available


    June 2014
  34. FREDERICK CB, Snellman K, Putnam RD
    Reply to Gao et al: Racial composition does not explain increasing class gaps in obesity.
    Proc Natl Acad Sci U S A. 2014;111:E2238.
    PubMed     Text format    


    May 2014
  35. SJOLUND J, Pelorosso FG, Quigley DA, DelRosario R, et al
    Identification of Hipk2 as an essential regulator of white fat development.
    Proc Natl Acad Sci U S A. 2014;111:7373-8.
    PubMed     Text format     Abstract available


  36. YONGQING G, Gordon J, Sun W
    Is poverty associated with obesity among American children?
    Proc Natl Acad Sci U S A. 2014 May 19. pii: 201405656.
    PubMed     Text format    


    April 2014
  37. CANAAN A, Defuria J, Perelman E, Schultz V, et al
    Extended lifespan and reduced adiposity in mice lacking the FAT10 gene.
    Proc Natl Acad Sci U S A. 2014;111:5313-8.
    PubMed     Text format     Abstract available


    February 2014

  38. Correction for Chatzigeorgiou et al., Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
    Proc Natl Acad Sci U S A. 2014.
    PubMed     Text format    


  39. CHATZIGEORGIOU A, Seijkens T, Zarzycka B, Engel D, et al
    Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
    Proc Natl Acad Sci U S A. 2014.
    PubMed     Text format     Abstract available


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