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Obesity

Free Subscription Articles published in Diabetes Retrieve available abstracts of 150 articles: HTML format

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June 2009
1. BOTTCHER Y , Unbehauen H, Kloting N, Ruschke K, et al
   Adipose Tissue Expression and Genetic Variants of the Bone Morphogenetic Protein Receptor 1A Gene (BMPR1A) are Associated with Human Obesity.
   Diabetes. 2009.
   PubMed     Related articles    Abstract available
   
   
   May 2009
2. STRAZNICKY NE , Lambert GW, McGrane MT, Masuo K, et al
   Weight loss may reverse blunted sympathetic neural responsiveness to glucose ingestion in obese subjects with metabolic syndrome.
   Diabetes. 2009;58:1126-32.
   PubMed     Related articles    Abstract available
   
   
   April 2009
3. SAITO M , Okamatsu-Ogura Y, Matsushita M, Watanabe K, et al
   High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity.
   Diabetes. 2009.
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4. CAPEL F , Klimcakova E, Viguerie N, Roussel B, et al
   Macrophages and Adipocytes in Human Obesity: Adipose Tissue Gene Expression and Insulin Sensitivity during Calorie Restriction and Weight Stabilization.
   Diabetes. 2009.
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5. ISAKSON P , Hammarstedt A, Gustafson B, Smith U, et al
   Impaired preadipocyte differentiation in human abdominal obesity -- role of Wnt, TNF{alpha} and inflammation.
   Diabetes. 2009.
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6. DEFRONZO RA
   Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus.
   Diabetes. 2009;58:773-95.
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7. KINDBLOM JM , Lorentzon M, Hellqvist A, Lonn L, et al
   BMI changes during childhood and adolescence as predictors of amount of adult subcutaneous and visceral adipose tissue in men: the GOOD Study.
   Diabetes. 2009;58:867-74.
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8. MATVEYENKO AV , Gurlo T, Daval M, Butler AE, et al
   Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced beta-cell endoplasmic reticulum stress.
   Diabetes. 2009;58:906-16.
   PubMed     Related articles    Abstract available
   
   
   March 2009
9. BODEN G
   Endoplasmic reticulum stress: another link between obesity and insulin resistance/inflammation?
   Diabetes. 2009;58:518-9.
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10. MANTOVANI G , Bondioni S, Alberti L, Gilardini L, et al
    Protein kinase A regulatory subunits in human adipose tissue: decreased R2B expression and activity in adipocytes from obese subjects.
    Diabetes. 2009;58:620-6.
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11. PADMALAYAM I , Hasham S, Saxena U, Pillarisetti S, et al
    Lipoic acid synthase (LASY): a novel role in inflammation, mitochondrial function, and insulin resistance.
    Diabetes. 2009;58:600-8.
    PubMed     Related articles    Abstract available
    
    
    
12. GREGOR MF , Yang L, Fabbrini E, Mohammed BS, et al
    Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss.
    Diabetes. 2009;58:693-700.
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13. YOUN BS , Bang SI, Kloting N, Park JW, et al
    Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue.
    Diabetes. 2009;58:627-36.
    PubMed     Related articles    Abstract available
    
    
    February 2009
14. CLOUGH G , Turzyniecka M, Walter L, Krentz A, et al
    Muscle Microvascular Dysfunction in Central Obesity is Related to Muscle Insulin Insensitivity but is not Reversed by High-Dose Statin Treatment.
    Diabetes. 2009.
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15. WILKES JJ , Lloyd DJ, Gekakis N
    A LOSS-OF-FUNCTION MUTATION IN MYOSTATIN REDUCES TNF{alpha} PRODUCTION AND PROTECTS LIVER AGAINST OBESITY-INDUCED INSULIN RESISTANCE.
    Diabetes. 2009.
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16. TAMASHIRO KL , Terrillion CE, Hyun J, Koenig JI, et al
    Prenatal Stress or High Fat Diet increases Susceptibility to Diet-Induced Obesity in Rat Offspring.
    Diabetes. 2009.
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17. XIE H , Lim B, Lodish HF
    MicroRNAs Induced during Adipogenesis That Accelerate Fat Cell Development Are Downregulated in Obesity.
    Diabetes. 2009.
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18. LINDSAY RS
    Many HAPO returns: maternal glycemia and neonatal adiposity: new insights from the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study.
    Diabetes. 2009;58:302-3.
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19. CEFALU WT
    Inflammation, insulin resistance, and type 2 diabetes: back to the future?
    Diabetes. 2009;58:307-8.
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    January 2009
20. STEINBERG GR , Watt MJ, Ernst M, Birnbaum MJ, et al
    CNTF Stimulates Muscle Glucose Uptake by a PI3-Kinase Dependent Pathway that is Impaired with Obesity.
    Diabetes. 2009.
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21. HWANG JH , Kim DW, Jo EJ, Kim YK, et al
    Pharmacological Stimulation of NADH Oxidation Ameliorates Obesity and Related Phenotypes in Mice.
    Diabetes. 2009.
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22. AHMADIAN M , Duncan RE, Varady KA, Frasson D, et al
    Adipose Overexpression of Desnutrin Promotes Fatty Acid Utilization and Attenuates Diet-induced Obesity.
    Diabetes. 2009.
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23. STIMSON RH , Andersson J, Andrew R, Redhead DN, et al
    Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans.
    Diabetes. 2009;58:46-53.
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24. RIBEL-MADSEN R , Friedrichsen M, Vaag A, Poulsen P, et al
    Retinol-binding protein 4 in twins: regulatory mechanisms and impact of circulating and tissue expression levels on insulin secretion and action.
    Diabetes. 2009;58:54-60.
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25. XU J , Lloyd DJ, Hale C, Stanislaus S, et al
    Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice.
    Diabetes. 2009;58:250-9.
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26. HITTEL DS , Berggren JR, Shearer J, Boyle K, et al
    Increased secretion and expression of myostatin in skeletal muscle from extremely obese women.
    Diabetes. 2009;58:30-8.
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    December 2008
27. HALLSCHMID M , Randeva H, Tan BK, Kern W, et al
    Relationship of Cerebrospinal Fluid Visfatin (PBEF/Nampt) Levels to Adiposity in Humans.
    Diabetes. 2008.
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28. PASARICA M , Sereda OR, Redman LM, Albarado DC, et al
    Reduced Adipose Tissue Oxygenation in Human Obesity - Evidence for Rarefaction, Macrophage Chemotaxis and Inflammation without an Angiogenic Response.
    Diabetes. 2008.
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29. ZOBEL DP , Andreasen CH, Grarup N, Eiberg H, et al
    Variants near MC4R associate with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes.
    Diabetes. 2008.
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30. TFAYLI H , Bacha F, Gungor N, Arslanian S, et al
    Phenotypic Type 2 Diabetes in Obese Youth: Insulin Sensitivity and Secretion in Islet-cell Antibody Negative vs. Antibody Positive Patients.
    Diabetes. 2008.
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31. TIMPSON NJ , Lindgren CM, Weedon MN, Randall J, et al
    Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome wide association data.
    Diabetes. 2008.
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32. KRAKOFF J , Ma L, Kobes S, Knowler WC, et al
    Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant.
    Diabetes. 2008;57:3267-72.
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33. BARATTA R , Rossetti P, Prudente S, Barbetti F, et al
    Role of the ENPP1 K121Q polymorphism in glucose homeostasis.
    Diabetes. 2008;57:3360-4.
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    November 2008
34. JIMENEZ-CHILLARON JC , Isganaitis E, Charalambous M, Gesta S, et al
    Intergenerational Transmission of Glucose Intolerance and Obesity by In Utero Undernutrition in Mice.
    Diabetes. 2008.
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35. ORTEGA E , Xu X, Koska J, Marie Francisco A, et al
    Macrophage content in subcutaneous adipose tissue: associations with adiposity, age, inflammatory markers, and whole-body insulin action in healthy Pima Indians.
    Diabetes. 2008.
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36. HAUS JM , Kashyap SR, Kasumov T, Zhang R, et al
    Plasma Ceramides Are Elevated in Obese Subjects with Type 2 Diabetes and Correlate with the Severity of Insulin Resistance.
    Diabetes. 2008.
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37. O'RAHILLY S , Farooqi IS
    Human obesity: a heritable neurobehavioral disorder that is highly sensitive to environmental conditions.
    Diabetes. 2008;57:2905-10.
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38. NEGRAO MR , Monteiro R, Calhau C, Soares R, et al
    Comment on: Hosogai et al. (2007) Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes 56:901-911, 2007.
    Diabetes. 2008;57:e15.
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39. NOGUEIRAS R , Veyrat-Durebex C, Suchanek PM, Klein M, et al
    Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats.
    Diabetes. 2008;57:2977-91.
    PubMed     Related articles    Abstract available
    
    
    October 2008
40. BERTOLA A , Deveaux V, Bonnafous S, Rousseau D, et al
    Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity.
    Diabetes. 2008.
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41. LIEB W , Pencina MJ, Lanier KJ, Tofler GH, et al
    Association of Parental Obesity with Concentrations of Select Systemic Biomarkers in Non-obese Offspring: The Framingham Heart Study.
    Diabetes. 2008.
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42. BASU R , Basu A, Grudzien M, Jung P, et al
    The Liver is the Site of Splanchnic Cortisol Production in Obese Non-diabetic Humans.
    Diabetes. 2008.
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43. JIAO P , Chen Q, Shah S, Du J, et al
    Obesity-related Upregulation of Monocyte Chemotactic Factors in Adipocytes: Involvement of NF-{kappa} B and JNK Pathways.
    Diabetes. 2008.
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44. VILLENA JA , Choi CS, Wang Y, Kim S, et al
    Resistance to high fat diet-induced obesity but exacerbated insulin resistance in mice overexpressing Pref-1: a new model of partial lipodystrophy.
    Diabetes. 2008.
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45. LEDOUX S , Queguiner I, Msika S, Calderari S, et al
    Angiogenesis Associated with Visceral and Subcutaneous Adipose Tissue in Severe Human Obesity.
    Diabetes. 2008.
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46. LUMENG CN , Delproposto JB, Westcott DJ, Saltiel AR, et al
    Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes.
    Diabetes. 2008.
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47. TOMLINSON JW , Finney J, Gay C, Hughes BA, et al
    Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity.
    Diabetes. 2008;57:2652-60.
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48. REYNA SM , Ghosh S, Tantiwong P, Meka CS, et al
    Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects.
    Diabetes. 2008;57:2595-602.
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    September 2008
49. WILLIAMS K , Tchernof A, Hunt KJ, Wagenknecht LE, et al
    Diabetes, abdominal adiposity, and atherogenic dyslipoproteinemia in women compared to men.
    Diabetes. 2008.
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50. HENZE A , Frey SK, Raila J, Tepel M, et al
    Evidence that kidney function but not type 2 diabetes mellitus determines retinol-binding protein 4 (RBP4) serum levels.
    Diabetes. 2008.
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51. BODEN G , Duan X, Homko C, Molina EJ, et al
    Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals.
    Diabetes. 2008;57:2438-44.
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52. STUTZMANN F , Tan K, Vatin V, Dina C, et al
    Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees.
    Diabetes. 2008;57:2511-8.
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53. KEBEDE M , Alquier T, Latour MG, Semache M, et al
    The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.
    Diabetes. 2008;57:2432-7.
    PubMed     Related articles    Abstract available
    
    
    August 2008
54. JOY ESPIRITU D , Mazzone T
    Oxidative stress regulates adipocyte apolipoprotein E and suppresses its expression in obesity.
    Diabetes. 2008.
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55. GORAN MI , Lane C, Toledo-Corral C, Weigensberg MJ, et al
    Persistence of Pre-Diabetes in Overweight and Obese Hispanic Children: Association With Progressive Insulin Resistance, Poor Beta-cell Function and Increasing Visceral Fat.
    Diabetes. 2008.
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56. SHEN L , Tso P, Woods SC, Clegg DJ, et al
    Brain apolipoprotein E: an important regulator of food intake in rats.
    Diabetes. 2008;57:2092-8.
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57. TAN CP , Feng Y, Zhou YP, Eiermann GJ, et al
    Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice.
    Diabetes. 2008;57:2211-9.
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58. DALLAIRE P , Bellmann K, Laplante M, Gelinas S, et al
    Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism.
    Diabetes. 2008;57:1999-2011.
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    July 2008
59. QI L , Kang K, Zhang C, van Dam RM, et al
    FTO Gene Variant Is Associated with Obesity: Longitudinal Analyses in Two Cohort Studies and Functional Test.
    Diabetes. 2008.
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60. TAN JT , Dorajoo R, Seielstad M, Sim X, et al
    FTO variants are associated with obesity in the Chinese and Malay populations in Singapore.
    Diabetes. 2008;.
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61. NISWENDER KD , Beech BM
    Obesity: increasing awareness of novel environmental factors.
    Diabetes. 2008;57:1786-7.
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62. COHEN DA
    Neurophysiological pathways to obesity: below awareness and beyond individual control.
    Diabetes. 2008;57:1768-73.
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63. LEVINE JA , Davis RM
    The Pol-e-pill finally arrives.
    Diabetes. 2008;57:1784-5.
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64. PICHA KM , Cunningham MR, Drucker DJ, Mathur A, et al
    Protein engineering strategies for sustained glucagon-like peptide-1 receptor-dependent control of glucose homeostasis.
    Diabetes. 2008;57:1926-34.
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65. JOCKEN JW , Roepstorff C, Goossens GH, van der Baan P, et al
    Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation.
    Diabetes. 2008;57:1834-41.
    PubMed     Related articles    Abstract available
    
    
    June 2008
66. MZHAVIA N , Yu S, Ikeda S, Chu TT, et al
    Neuronatin: a new inflammation gene expressed on the aortic endothelium of diabetic mice.
    Diabetes. 2008;.
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67. MAIER C , Riedl M, Vila G, Nowotny P, et al
    Cholinergic regulation of ghrelin and PYY release may be impaired in obesity.
    Diabetes. 2008;.
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68. GRARUP N , Andersen G, Krarup NT, Albrechtsen A, et al
    Association testing of novel type 2 diabetes risk-alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
    Diabetes. 2008;.
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69. MAKINEN VP , Forsblom C, Thorn LM, Waden J, et al
    Metabolic Phenotypes, Vascular Complications and Premature Deaths in a Population of 4,197 Patients with Type 1 Diabetes.
    Diabetes. 2008;.
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70. TOMLINSON JW , Finney J, Hughes BA, Hughes SV, et al
    Reduced glucocorticoid production rate, decreased 5alpha-reductase activity, and adipose tissue insulin sensitization after weight loss.
    Diabetes. 2008;57:1536-43.
    PubMed     Related articles    Abstract available
    
    
    May 2008
71. CHANG YC , Liu PH, Lee WJ, Chang TJ, et al
    Common Variation in the FTO Gene Confers Risk of Obesity and Modulates Body Mass Index in the Chinese Population.
    Diabetes. 2008;.
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72. NG MC , Park KS, Oh B, Tam CH, et al
    Implication of Genetic Variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2 and FTO in Type 2 Diabetes and Obesity in 6719 Asians.
    Diabetes. 2008;.
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73. HANLEY AJ , Wagenknecht LE
    Abdominal adiposity and diabetes risk: the importance of precise measures and longitudinal studies.
    Diabetes. 2008;57:1153-5.
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    April 2008
74. MARVELLE AF , Lange LA, Qin L, Adair LS, et al
    Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) cohort.
    Diabetes. 2008;.
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75. FERAL CC , Neels JG, Kummer C, Slepak M, et al
    Blockade of {alpha}4 integrin Signaling Ameliorates the Metabolic Consequences of High Fat Diet-Induced Obesity.
    Diabetes. 2008;.
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76. ABDULHADI-ATWAN M , Bushmann J, Tornovsky-Babaey S, Perry A, et al
    Novel de novo mutation in SUR1 presenting as hyperinsulinism in infancy followed by overt diabetes in early adolescence.
    Diabetes. 2008;.
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77. TOLEDO FG , Menshikova EV, Azuma K, Radikova Z, et al
    Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content.
    Diabetes. 2008;57:987-94.
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78. CHAVEZ AO , Lopez-Alvarenga JC, Tejero ME, Triplitt C, et al
    Physiological and molecular determinants of insulin action in the baboon.
    Diabetes. 2008;57:899-908.
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79. TAN BK , Adya R, Farhatullah S, Lewandowski KC, et al
    Omentin-1, a novel adipokine, is decreased in overweight insulin-resistant women with polycystic ovary syndrome: ex vivo and in vivo regulation of omentin-1 by insulin and glucose.
    Diabetes. 2008;57:801-8.
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    March 2008
80. LI M , Hyun Kim D, Tsenovoy PL, Peterson SJ, et al
    Treatment of Obese Diabetic Mice with an Heme Oxygenase Inducer Reduces Visceral and Subcutaneous Adiposity, Increases Adiponectin Levels and Improves Insulin Sensitivity and Glucose Tolerance.
    Diabetes. 2008;.
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81. FREATHY RM , Timpson NJ, Lawlor DA, Pouta A, et al
    Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected, given its effect on BMI.
    Diabetes. 2008;.
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82. MORI MA , Araujo RC, Reis FC, Sgai DG, et al
    Kinin B1 receptor deficiency leads to leptin hypersensitivity and resistance to obesity.
    Diabetes. 2008;.
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83. DO R , Bailey SD, Desbiens K, Belisle A, et al
    Genetic Variants of FTO Influence Adiposity, Insulin Sensitivity, Leptin Levels and Resting Metabolic Rate in the Quebec Family Study.
    Diabetes. 2008;.
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84. ANDERSEN G , Burgdorf KS, Sparso T, Borch-Johnsen K, et al
    AHSG tagSNPs associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 Danish whites.
    Diabetes. 2008;.
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85. MORRISON C
    Interaction between exercise and leptin in the treatment of obesity.
    Diabetes. 2008;57:534-5.
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86. FRIEDMAN JE , Kirwan JP, Jing M, Presley L, et al
    Increased skeletal muscle tumor necrosis factor-alpha and impaired insulin signaling persist in obese women with gestational diabetes mellitus 1 year postpartum.
    Diabetes. 2008;57:606-13.
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87. REINEHR T , Hinney A, Nguyen TT, Hebebrand J, et al
    Evidence of an influence of a polymorphism near the INSIG2 on weight loss during a lifestyle intervention in obese children and adolescents.
    Diabetes. 2008;57:623-6.
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    February 2008
88. CANI PD , Rodrigo B, Knauf C, Waget A, et al
    Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice.
    Diabetes. 2008;.
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89. HAYASHI T , Boyko EJ, McNeely MJ, Leonetti DL, et al
    Visceral Adiposity, not Abdominal Subcutaneous Fat Area, Is Associated with an Increase in Future Insulin Resistance in Japanese Americans.
    Diabetes. 2008;.
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90. RUOHONEN ST , Pesonen U, Moritz N, Kaipio K, et al
    Transgenic Mice Overexpressing Neuropeptide Y in Noradrenergic Neurons: A Novel Model of Increased Adiposity and Impaired Glucose Tolerance.
    Diabetes. 2008;.
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91. D'EON TM , Pierce KA, Roix JJ, Tyler A, et al
    The role of adipocyte insulin resistance in the pathogenesis of obesity-related elevations in endocannabinoids.
    Diabetes. 2008;.
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92. ZHANG X , Yeung DC, Karpisek M, Stejskal D, et al
    Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans.
    Diabetes. 2008;.
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93. VAN HARMELEN V , Eriksson A, Astrom G, Wahlen K, et al
    Vascular peptide endothelin-1 links fat accumulation with alterations of visceral adipocyte lipolysis.
    Diabetes. 2008;57:378-86.
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94. RISERUS U , Sprecher D, Johnson T, Olson E, et al
    Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men.
    Diabetes. 2008;57:332-9.
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95. TAKSALI SE , Caprio S, Dziura J, Dufour S, et al
    High visceral and low abdominal subcutaneous fat stores in the obese adolescent: a determinant of an adverse metabolic phenotype.
    Diabetes. 2008;57:367-71.
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96. LE STUNFF C , Dechartres A, Mariot V, Lotton C, et al
    Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children.
    Diabetes. 2008;57:494-502.
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97. HOJLUND K , Glintborg D, Andersen NR, Birk JB, et al
    Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment.
    Diabetes. 2008;57:357-66.
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98. BREZNICEANU ML , Liu F, Wei CC, Chenier I, et al
    Attenuation of interstitial fibrosis and tubular apoptosis in db/db transgenic mice overexpressing catalase in renal proximal tubular cells.
    Diabetes. 2008;57:451-9.
    PubMed     Related articles    Abstract available
    
    
    January 2008
99. ANDREASEN CH , Stender-Petersen KL, Mogensen MS, Torekov SS, et al
    Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation.
    Diabetes. 2008;57:95-101.
    PubMed     Related articles    Abstract available
    
    
    December 2007
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