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FPG #8: Alternative Treatments in Psychiatry
FPG #7: Critical Care in Neurology

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  Multiple Sclerosis

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Articles published in Ann Neurol

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    January 2012
  1. ROSSI S , Furlan R, De Chiara V, Motta C, et al
    Interleukin-1beta causes synaptic hyperexcitability in multiple sclerosis.
    Ann Neurol. 2012;71:76-83.
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    December 2011
  2. OKSENBERG JR , Hauser SL
    Decoding multiple sclerosis.
    Ann Neurol. 2011;70:A5-7.
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  3. PATSOPOULOS NA , de Bakker PI
    Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
    Ann Neurol. 2011;70:897-912.
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  4. BLANKENHORN EP , Butterfield R, Case LK, Wall EH, et al
    Genetics of experimental allergic encephalomyelitis supports the role of T helper cells in multiple sclerosis pathogenesis.
    Ann Neurol. 2011;70:887-96.
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  5. RAMAGOPALAN SV , Dyment DA, Cader MZ, Morrison KM, et al
    Rare variants in the CYP27B1 gene are associated with multiple sclerosis.
    Ann Neurol. 2011;70:881-6.
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    November 2011
  6. MOLL NM , Rietsch AM, Thomas S, Ransohoff AJ, et al
    Multiple sclerosis normal-appearing white matter: Pathology-imaging correlations.
    Ann Neurol. 2011;70:764-73.
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  7. BOZIC C , Richman S, Plavina T, Natarajan A, et al
    Anti-John Cunnigham virus antibody prevalence in multiple sclerosis patients: Baseline results of STRATIFY-1.
    Ann Neurol. 2011;70:713-21.
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  8. PONSONBY AL , Lucas RM
    Shift work and multiple sclerosis.
    Ann Neurol. 2011;70:680-3.
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    October 2011
  9. HEDSTROM AK , Akerstedt T, Hillert J, Olsson T, et al
    Shift work at young age is associated with increased risk for multiple sclerosis.
    Ann Neurol. 2011 Oct 17. doi: 10.1002/ana.22597.
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  10. WINKELMANN A , Loebermann M, Reisinger EC, Peter Hartung H, et al
    Fingolimod treatment for multiple sclerosis Patients What Do We Do with Varicella?
    Ann Neurol. 2011;70:673-4.
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  11. QIAN P , Cadavid D, Wolansky LJ, Cook SD, et al
    Heterogeneity in longitudinal evolution of ring-enhancing multiple sclerosis lesions.
    Ann Neurol. 2011;70:668-9.
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  12. BUSTAMANTE MF , Fissolo N, Rio J, Espejo C, et al
    Implication of the toll-like receptor 4 pathway in the response to interferon-beta in multiple sclerosis.
    Ann Neurol. 2011;70:634-45.
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    September 2011
  13. STEINER I
    On human disease and animal models.
    Ann Neurol. 2011;70:343-4.
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  14. TUMANI H , Deisenhammer F, Giovannoni G, Gold R, et al
    Revised McDonald criteria: the persisting importance of cerebrospinal fluid analysis.
    Ann Neurol. 2011;70:520.
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    July 2011
  15. GALEA I , Freedman MS, Thompson EJ
    Cerebrospinal fluid analysis in the 2010 revised McDonald's multiple sclerosis diagnostic criteria.
    Ann Neurol. 2011;70:183.
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  16. CENTONZE D , Floris R, Stefanini M, Rossi S, et al
    Proposed chronic cerebrospinal venous insufficiency criteria do not predict multiple sclerosis risk or severity.
    Ann Neurol. 2011;70:52-9.
    PubMed     Text format     Related articles    Abstract available



  17. MIRZAEI F , Michels KB, Munger K, O'Reilly E, et al
    Gestational vitamin D and the risk of multiple sclerosis in offspring.
    Ann Neurol. 2011;70:30-40.
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  18. CUTTER G , Salter A
    Got milk?
    Ann Neurol. 2011;70:3-4.
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    June 2011
  19. VAN DER KOP ML , Pearce MS, Dahlgren L, Synnes A, et al
    Neonatal and delivery outcomes in women with multiple sclerosis.
    Ann Neurol. 2011 Jun 27. doi: 10.1002/ana.22483.
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  20. LASSMANN H
    A dynamic view of the blood-brain barrier in active multiple sclerosis lesions.
    Ann Neurol. 2011 Jun 2. doi: 10.1002/ana.22494.
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  21. ZIVADINOV R , Ramanathan M, Dwyer MG, Marr K, et al
    Comment on "no evidence of chronic cerebrospinal venous insufficiency at multiple sclerosis onset".
    Ann Neurol. 2011;69:1062-3.
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  22. KOEL-SIMMELINK MJ , Teunissen CE, Behradkia P, Blankenstein MA, et al
    The neurofilament light chain is not stable in vitro.
    Ann Neurol. 2011;69:1065-6.
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    May 2011
  23. KILSDONK ID , Barkhof F, Wattjes MP
    2010 revisions to mcDonald criteria for diagnosis of multiple sclerosis: Impact of 3-tesla magnetic resonance imaging.
    Ann Neurol. 2011 May 26. doi: 10.1002/ana.22490.
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  24. GAITAN MI , Shea CD, Evangelou IE, Stone RD, et al
    Evolution of the blood-brain barrier in newly forming multiple sclerosis lesions.
    Ann Neurol. 2011 May 11. doi: 10.1002/ana.22472.
    PubMed     Text format     Related articles    Abstract available



  25. COHEN JA , Chun J
    Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis.
    Ann Neurol. 2011;69:759-77.
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    April 2011
  26. GIAMPIERO A
    Chronic cerebrospinal venous insufficiency and susceptibility to multiple sclerosis.
    Ann Neurol. 2011 Apr 12. doi: 10.1002/ana.22451.
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  27. AXTHELM MK , Bourdette DN, Marracci GH, Su W, et al
    Japanese macaque encephalomyelitis: A spontaneous multiple sclerosis-like disease in a nonhuman primate.
    Ann Neurol. 2011 Apr 7. doi: 10.1002/ana.22449.
    PubMed     Text format     Related articles    Abstract available



  28. KREMER D , Aktas O, Hartung HP, Kury P, et al
    The complex world of oligodendroglial differentiation inhibitors.
    Ann Neurol. 2011;69:602-18.
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  29. HAO J , Campagnolo D, Liu R, Piao W, et al
    Interleukin-2/interleukin-2 antibody therapy induces target organ natural killer cells that inhibit central nervous system inflammation.
    Ann Neurol. 2011;69:721-34.
    PubMed     Text format     Related articles    Abstract available



  30. ZAHEDNASAB H , Bahreini SA
    Interferon-beta and toll-like receptor-9 processing.
    Ann Neurol. 2011;69:740-1.
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    March 2011
  31. CAMPBELL GR , Ziabreva I, Reeve AK, Krishnan KJ, et al
    Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis.
    Ann Neurol. 2011;69:481-92.
    PubMed     Text format     Related articles    Abstract available



  32. DUTTA R , Chang A, Doud MK, Kidd GJ, et al
    Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients.
    Ann Neurol. 2011;69:445-54.
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  33. AKTAS O , Hartung HP
    Beyond axonal transection: Hippocampal damage in multiple sclerosis.
    Ann Neurol. 2011;69:433-6.
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    February 2011
  34. MEHLING M , Hilbert P, Fritz S, Durovic B, et al
    Antigen-specific adaptive immune responses in fingolimod-treated multiple sclerosis patients.
    Ann Neurol. 2011;69:408-13.
    PubMed     Text format     Related articles    Abstract available



  35. POLMAN CH , Reingold SC, Banwell B, Clanet M, et al
    Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria.
    Ann Neurol. 2011;69:292-302.
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  36. RUDICK RA
    Diagnostic criteria in multiple sclerosis: Headed in the right direction but still a ways to go.
    Ann Neurol. 2011;69:234-6.
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    January 2011
  37. CORREALE J , Villa A
    Role of CD8 regulatory T Cells in multiple sclerosis.
    Ann Neurol. 2011 Jan 19. doi: 10.1002/ana.22302.
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  38. BARACCHINI C , Perini P, Calabrese M, Causin F, et al
    No evidence of chronic cerebrospinal venous insufficiency at multiple sclerosis onset.
    Ann Neurol. 2011;69:90-9.
    PubMed     Text format     Related articles    Abstract available



  39. GUNNARSSON M , Malmestrom C, Axelsson M, Sundstrom P, et al
    Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab.
    Ann Neurol. 2011;69:83-9.
    PubMed     Text format     Related articles    Abstract available



  40. COMI G , Cohen JA, Arnold DL, Wynn D, et al
    Phase III dose-comparison study of glatiramer acetate for multiple sclerosis.
    Ann Neurol. 2011;69:75-82.
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  41. GOURRAUD PA , McElroy JP, Caillier SJ, Johnson BA, et al
    Aggregation of multiple sclerosis genetic risk variants in multiple and single case families.
    Ann Neurol. 2011;69:65-74.
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  42. HARDY J , Thompson AJ
    Dissecting the familial risk of multiple sclerosis.
    Ann Neurol. 2011;69:11-2.
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  43. COHEN R , Blight AR
    4-Aminopyridine: new life for an old drug. Reply.
    Ann Neurol. 2011;69:218-20.
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  44. WARNKE C , Adams O, Hartung HP, Kieseier BC, et al
    Assessment of JC virus DNA in blood and urine from natalizumab-treated patients.
    Ann Neurol. 2011;69:215-6.
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    December 2010
  45. KHOURY S , Bakshi R
    Cerebral pseudoatrophy or real atrophy after therapy in multiple sclerosis.
    Ann Neurol. 2010;68:778-9.
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  46. PETZOLD A , Mondria T, Kuhle J, Rocca MA, et al
    Evidence for acute neurotoxicity after chemotherapy.
    Ann Neurol. 2010;68:806-15.
    PubMed     Text format     Related articles    Abstract available



    November 2010
  47. BALASHOV KE , Aung LL, Vaknin-Dembinsky A, Dhib-Jalbut S, et al
    Interferon-beta inhibits toll-like receptor 9 processing in multiple sclerosis.
    Ann Neurol. 2010.
    PubMed     Text format     Related articles    Abstract available



  48. CAMPBELL GR , Ziabreva I, Reeve AK, Krishnan KJ, et al
    Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis.
    Ann Neurol. 2010.
    PubMed     Text format     Related articles    Abstract available



  49. ZAMBONI P
    Regarding "No Cerebrocervical Venous Congestion in Patients with Multiple Sclerosis. Intraluminal Jugular Septation"
    Ann Neurol. 2010.
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  50. GEURTS JJ , Kooi EJ, Witte ME, van der Valk P, et al
    Multiple sclerosis as an "Inside-out" disease.
    Ann Neurol. 2010;68:767-8.
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  51. JURYNCZYK M , Walczak A, Jurewicz A, Jesionek-Kupnicka D, et al
    Immune regulation of multiple sclerosis by transdermally applied myelin peptides.
    Ann Neurol. 2010;68:593-601.
    PubMed     Text format     Related articles    Abstract available



  52. STEINMAN L , Zamvil SS
    Delivery of myelin peptides through the first line of defense, skin, to counter autoimmunity in multiple sclerosis.
    Ann Neurol. 2010;68:567-9.
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  53. DAMMANN O , Leviton A
    The challenge of causal inference.
    Ann Neurol. 2010;68:770.
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  54. APIWATTANAKUL M , Popescu BF, Matiello M, Weinshenker BG, et al
    Intractable vomiting as the initial presentation of neuromyelitis optica.
    Ann Neurol. 2010;68:757-61.
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  55. PIORO EP , Brooks BR, Cummings J, Schiffer R, et al
    Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect.
    Ann Neurol. 2010;68:693-702.
    PubMed     Text format     Related articles    Abstract available



    October 2010
  56. STANKOFF B , Freeman L, Aigrot MS, Chardain A, et al
    Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl-(11) C]-2-(4'-methylaminophenyl)- 6-hydroxybenzothiazole.
    Ann Neurol. 2010 Oct 29. doi: 10.1002/ana.22320.
    PubMed     Text format     Related articles    Abstract available



  57. GUNNARSSON M , Malmestrom C, Axelsson M, Sundstrom P, et al
    Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab.
    Ann Neurol. 2010.
    PubMed     Text format     Related articles    Abstract available



  58. RASMUSSEN S , Imitola J, Ayuso-Sacido A, Wang Y, et al
    Reversible neural stem cell niche dysfunction in a model of multiple sclerosis.
    Ann Neurol. 2010 Oct 28. doi: 10.1002/ana.22299.
    PubMed     Text format     Related articles    Abstract available



  59. KREFT KL , Verbraak E, Wierenga-Wolf AF, Laman JD, et al
    Role of CD8 regulatory T-cells in multiple sclerosis.
    Ann Neurol. 2010 Oct 28. doi: 10.1002/ana.22288.
    PubMed     Text format     Related articles   



  60. SIMKA M , Kazibudzki M
    Chronic cerebrospinal venous insufficiency and multiple sclerosis: A commentary.
    Ann Neurol. 2010;68:562-3.
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  61. BEGGS C
    Multiple sclerosis appears To be associated with cerebral venous abnormalities.
    Ann Neurol. 2010;68:560-1.
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  62. GOODMAN AD , Brown TR, Edwards KR, Krupp LB, et al
    A phase 3 trial of extended release oral dalfampridine in multiple sclerosis.
    Ann Neurol. 2010;68:494-502.
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  63. MAGLIOZZI R , Howell OW, Reeves C, Roncaroli F, et al
    A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis.
    Ann Neurol. 2010;68:477-93.
    PubMed     Text format     Related articles    Abstract available



    September 2010
  64. BERGER JR , Centonze D, Comi G, Confavreux C, et al
    Considerations on discontinuing natalizumab for the treatment of multiple sclerosis.
    Ann Neurol. 2010;68:409-11.
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  65. RYSCHKEWITSCH CF , Jensen PN, Monaco MC, Major EO, et al
    JC virus persistence following progressive multifocal leukoencephalopathy in multiple sclerosis patients treated with natalizumab.
    Ann Neurol. 2010;68:384-91.
    PubMed     Text format     Related articles    Abstract available



  66. WEST TW , Cree BA
    Natalizumab dosage suspension: are we helping or hurting?
    Ann Neurol. 2010;68:395-9.
    PubMed     Text format     Related articles    Abstract available



    August 2010
  67. ANDRODIAS G , Reynolds R, Chanal M, Ritleng C, et al
    Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords.
    Ann Neurol. 2010.
    PubMed     Text format     Related articles    Abstract available



  68. HANDEL AE , Lincoln MR, Ramagopalan SV
    Chronic cerebrospinal venous insufficiency and multiple sclerosis.
    Ann Neurol. 2010;68:270.
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  69. SUNDSTROM P , Wahlin A, Ambarki K, Birgander R, et al
    Venous and cerebrospinal fluid flow in multiple sclerosis: A case-control study.
    Ann Neurol. 2010;68:255-9.
    PubMed     Text format     Related articles    Abstract available



  70. SIMPSON S JR , Taylor B, Blizzard L, Ponsonby AL, et al
    Higher 25-hydroxyvitamin D is associated with lower relapse risk in multiple sclerosis.
    Ann Neurol. 2010;68:193-203.
    PubMed     Text format     Related articles    Abstract available



  71. DOEPP F , Paul F, Valdueza JM, Schmierer K, et al
    No cerebrocervical venous congestion in patients with multiple sclerosis.
    Ann Neurol. 2010;68:173-83.
    PubMed     Text format     Related articles    Abstract available



  72. CREE BA , Kornyeyeva E, Goodin DS
    Pilot trial of low-dose naltrexone and quality of life in multiple sclerosis.
    Ann Neurol. 2010;68:145-50.
    PubMed     Text format     Related articles    Abstract available



    July 2010
  73. KILLESTEIN J , Vennegoor A, Strijbis EM, Seewann A, et al
    Natalizumab drug holiday in multiple sclerosis: Poorly Tolerated.
    Ann Neurol. 2010.
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  74. DARLINGTON PJ , Boivin MN, Renoux C, Francois M, et al
    Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: Implication for multiple sclerosis.
    Ann Neurol. 2010.
    PubMed     Text format     Related articles    Abstract available



  75. BRAHIC M
    Multiple sclerosis and viruses.
    Ann Neurol. 2010;68:6-8.
    PubMed     Text format     Related articles    Abstract available



  76. BITTNER S , Bobak N, Herrmann AM, Gobel K, et al
    Upregulation of K(2P)5.1 potassium channels in multiple sclerosis.
    Ann Neurol. 2010;68:58-69.
    PubMed     Text format     Related articles    Abstract available



  77. HAUSER SL , Johnston SC
    4-aminopyridine: new life for an old drug.
    Ann Neurol. 2010;68:A8-9.
    PubMed     Text format     Related articles   



    June 2010
  78. LEVIN LI , Munger KL, O'Reilly EJ, Falk KI, et al
    Primary infection with the Epstein-Barr virus and risk of multiple sclerosis.
    Ann Neurol. 2010;67:824-30.
    PubMed     Text format     Related articles    Abstract available



  79. TALMAN LS , Bisker ER, Sackel DJ, Long DA Jr, et al
    Longitudinal study of vision and retinal nerve fiber layer thickness in multiple sclerosis.
    Ann Neurol. 2010;67:749-60.
    PubMed     Text format     Related articles    Abstract available



    May 2010
  80. RAMAGOPALAN SV , Dyment DA, Giovannoni G, Sadovnick AD, et al
    HLA-DRB1*15, low infant sibling exposure, and multiple sclerosis gene-environment interaction.
    Ann Neurol. 2010;67:694-5.
    PubMed     Text format     Related articles   



  81. MORAAL B , van den Elskamp IJ, Knol DL, Uitdehaag BM, et al
    Long-interval T2-weighted subtraction magnetic resonance imaging: a powerful new outcome measure in multiple sclerosis trials.
    Ann Neurol. 2010;67:667-75.
    PubMed     Text format     Related articles    Abstract available



  82. CORREALE J , Villa A
    Role of CD8+ CD25+ Foxp3+ regulatory T cells in multiple sclerosis.
    Ann Neurol. 2010;67:625-38.
    PubMed     Text format     Related articles    Abstract available



  83. MOWRY EM , Krupp LB, Milazzo M, Chabas D, et al
    Vitamin D status is associated with relapse rate in pediatric-onset multiple sclerosis.
    Ann Neurol. 2010;67:618-24.
    PubMed     Text format     Related articles    Abstract available



    April 2010
  84. STECK A , Latov N
    Have we finally identified an autoimmune demyelinating disease?
    Ann Neurol. 2010;67:552.
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  85. BAR-OR A , Fawaz L, Fan B, Darlington PJ, et al
    Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?
    Ann Neurol. 2010;67:452-61.
    PubMed     Text format     Related articles    Abstract available



    March 2010
  86. CALABRESE M , Rocca MA, Atzori M, Mattisi I, et al
    A 3-year magnetic resonance imaging study of cortical lesions in relapse-onset multiple sclerosis.
    Ann Neurol. 2010;67:376-83.
    PubMed     Text format     Related articles    Abstract available



  87. KHAN O , Filippi M, Freedman MS, Barkhof F, et al
    Chronic cerebrospinal venous insufficiency and multiple sclerosis.
    Ann Neurol. 2010;67:286-90.
    PubMed     Text format     Related articles    Abstract available



    February 2010
  88. VAN DER MEI IA , Ponsonby AL, Taylor BV, Stankovich J, et al
    Human leukocyte antigen-DR15, low infant sibling exposure and multiple sclerosis: gene-environment interaction.
    Ann Neurol. 2010;67:261-5.
    PubMed     Text format     Related articles    Abstract available



  89. LUNEMANN JD , Tintore M, Messmer B, Strowig T, et al
    Elevated Epstein-Barr virus-encoded nuclear antigen-1 immune responses predict conversion to multiple sclerosis.
    Ann Neurol. 2010;67:159-69.
    PubMed     Text format     Related articles    Abstract available



  90. FOCOSI D
    Concerns on unpredictable pharmacokinetics and pharmacodynamics of natalizumab.
    Ann Neurol. 2010;67:270.
    PubMed     Text format     Related articles   



    January 2010
  91. SAWCER S , Ban M, Wason J, Dudbridge F, et al
    What role for genetics in the prediction of multiple sclerosis?
    Ann Neurol. 2010;67:3-10.
    PubMed     Text format     Related articles    Abstract available




  92. Experimental multiple sclerosis vascular shunting procedure halted at Stanford.
    Ann Neurol. 2010;67:A13-5.
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