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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Malignant Melanoma

Free Subscription Articles published in J Immunol Retrieve available abstracts of 88 articles: HTML format

Single Articles

July 2008
1. ADAMS S , O'Neill DW, Nonaka D, Hardin E, et al
   Immunization of Malignant Melanoma Patients with Full-Length NY-ESO-1 Protein Using TLR7 Agonist Imiquimod as Vaccine Adjuvant.
   J Immunol. 2008;181:776-84.
   PubMed     Related articles    Abstract available
   
   
   June 2008
2. WERNECK MB , Lugo-Villarino G, Hwang ES, Cantor H, et al
   T-Bet Plays a Key Role in NK-Mediated Control of Melanoma Metastatic Disease.
   J Immunol. 2008;180:8004-10.
   PubMed     Related articles    Abstract available
   
   
   May 2008
3. YOSHIMOTO T , Morishima N, Mizoguchi I, Shimizu M, et al
   Antiproliferative Activity of IL-27 on Melanoma.
   J Immunol. 2008;180:6527-35.
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   April 2008
4. FUERTES MB , Girart MV, Molinero LL, Domaica CI, et al
   Intracellular Retention of the NKG2D Ligand MHC Class I Chain-Related Gene A in Human Melanomas Confers Immune Privilege and Prevents NK Cell-Mediated Cytotoxicity.
   J Immunol. 2008;180:4606-14.
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   March 2008
5. HALLERMALM K , Seki K, De Geer A, Motyka B, et al
   Modulation of the Tumor Cell Phenotype by IFN-{gamma} Results in Resistance of Uveal Melanoma Cells to Granule-Mediated Lysis by Cytotoxic Lymphocytes.
   J Immunol. 2008;180:3766-74.
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6. JARNICKI AG , Conroy H, Brereton C, Donnelly G, et al
   Attenuating Regulatory T Cell Induction by TLR Agonists through Inhibition of p38 MAPK Signaling in Dendritic Cells Enhances Their Efficacy as Vaccine Adjuvants and Cancer Immunotherapeutics.
   J Immunol. 2008;180:3797-806.
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7. CARRASCO J , Van Pel A, Neyns B, Lethe B, et al
   Vaccination of a Melanoma Patient with Mature Dendritic Cells Pulsed with MAGE-3 Peptides Triggers the Activity of Nonvaccine Anti-Tumor Cells.
   J Immunol. 2008;180:3585-93.
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8. STRAUSS L , Bergmann C, Szczepanski MJ, Lang S, et al
   Expression of ICOS on Human Melanoma-Infiltrating CD4+CD25highFoxp3+ T Regulatory Cells: Implications and Impact on Tumor-Mediated Immune Suppression.
   J Immunol. 2008;180:2967-80.
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   February 2008
9. DUBOIS S , Patel HJ, Zhang M, Waldmann TA, et al
   Preassociation of IL-15 with IL-15R alpha-IgG1-Fc enhances its activity on proliferation of NK and CD8+/CD44high T cells and its antitumor action.
   J Immunol. 2008;180:2099-106.
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10. STOITZNER P , Green LK, Jung JY, Price KM, et al
    Tumor immunotherapy by epicutaneous immunization requires langerhans cells.
    J Immunol. 2008;180:1991-8.
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    January 2008
11. TORRES D , Paget C, Fontaine J, Mallevaey T, et al
    Prostaglandin D2 Inhibits the Production of IFN-{gamma} by Invariant NK T Cells: Consequences in the Control of B16 Melanoma.
    J Immunol. 2008;180:783-92.
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12. LENGAGNE R , Graff-Dubois S, Garcette M, Renia L, et al
    Distinct role for CD8 T cells toward cutaneous tumors and visceral metastases.
    J Immunol. 2008;180:130-7.
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    December 2007
13. KUDELA P , Janjic B, Fourcade J, Castelli F, et al
    Cross-Reactive CD4+ T Cells against One Immunodominant Tumor-Derived Epitope in Melanoma Patients.
    J Immunol. 2007;179:7932-40.
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14. DERRE L , Ferber M, Touvrey C, Devevre E, et al
    A Novel Population of Human Melanoma-Specific CD8 T Cells Recognizes Melan-AMART-1 Immunodominant Nonapeptide but Not the Corresponding Decapeptide.
    J Immunol. 2007;179:7635-45.
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    November 2007
15. GUEZGUEZ B , Vigneron P, Lamerant N, Kieda C, et al
    Dual Role of Melanoma Cell Adhesion Molecule (MCAM)/CD146 in Lymphocyte Endothelium Interaction: MCAM/CD146 Promotes Rolling via Microvilli Induction in Lymphocyte and Is an Endothelial Adhesion Receptor.
    J Immunol. 2007;179:6673-85.
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16. BARANEK T , Debret R, Antonicelli F, Lamkhioued B, et al
    Elastin receptor (spliced galactosidase) occupancy by elastin peptides counteracts proinflammatory cytokine expression in lipopolysaccharide-stimulated human monocytes through NF-kappaB down-regulation.
    J Immunol. 2007;179:6184-92.
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    October 2007
17. HOLLING TM , Bergevoet MW, Wilson L, Van Eggermond MC, et al
    A Role for EZH2 in Silencing of IFN-{gamma} Inducible MHC2TA Transcription in Uveal Melanoma.
    J Immunol. 2007;179:5317-25.
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18. WEINHOLD M , Sommermeyer D, Uckert W, Blankenstein T, et al
    Dual T Cell Receptor Expressing CD8+ T Cells with Tumor- and Self-Specificity Can Inhibit Tumor Growth without Causing Severe Autoimmunity.
    J Immunol. 2007;179:5534-42.
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19. ELSNER L , Muppala V, Gehrmann M, Lozano J, et al
    The heat shock protein HSP70 promotes mouse NK cell activity against tumors that express inducible NKG2D ligands.
    J Immunol. 2007;179:5523-33.
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20. BARITAKI S , Katsman A, Chatterjee D, Yeung KC, et al
    Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation.
    J Immunol. 2007;179:5441-53.
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21. LUKETIC L , Delanghe J, Sobol PT, Yang P, et al
    Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL.
    J Immunol. 2007;179:5024-32.
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22. POWELL DJ JR , Felipe-Silva A, Merino MJ, Ahmadzadeh M, et al
    Administration of a CD25-Directed Immunotoxin, LMB-2, to Patients with Metastatic Melanoma Induces a Selective Partial Reduction in Regulatory T Cells In Vivo.
    J Immunol. 2007;179:4919-28.
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    September 2007
23. HYKA-NOUSPIKEL N , Lucian L, Murphy E, McClanahan T, et al
    DAP10 Deficiency Breaks the Immune Tolerance against Transplantable Syngeneic Melanoma.
    J Immunol. 2007;179:3763-71.
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24. GUAN H , Nagarkatti PS, Nagarkatti M
    Blockade of Hyaluronan Inhibits IL-2-Induced Vascular Leak Syndrome and Maintains Effectiveness of IL-2 Treatment for Metastatic Melanoma.
    J Immunol. 2007;179:3715-23.
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25. GIRART MV , Fuertes MB, Domaica CI, Rossi LE, et al
    Engagement of TLR3, TLR7, and NKG2D regulate IFN-gamma secretion but not NKG2D-mediated cytotoxicity by human NK cells stimulated with suboptimal doses of IL-12.
    J Immunol. 2007;179:3472-9.
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    August 2007
26. DUNN IS , Haggerty TJ, Kono M, Durda PJ, et al
    Enhancement of Human Melanoma Antigen Expression by IFN-beta.
    J Immunol. 2007;179:2134-42.
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27. DERRE L , Bruyninx M, Baumgaertner P, Devevre E, et al
    In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration.
    J Immunol. 2007;179:2368-79.
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28. YU P , Lee Y, Wang Y, Liu X, et al
    Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases.
    J Immunol. 2007;179:1960-8.
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29. NITCHEU-TEFIT J , Dai MS, Critchley-Thorne RJ, Ramirez-Jimenez F, et al
    Listeriolysin O Expressed in a Bacterial Vaccine Suppresses CD4+CD25high Regulatory T Cell Function In Vivo.
    J Immunol. 2007;179:1532-1541.
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    July 2007
30. NICHOLS LA , Chen Y, Colella TA, Bennett CL, et al
    Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes.
    J Immunol. 2007;179:993-1003.
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    June 2007
31. ERFURT C , Sun Z, Haendle I, Schuler-Thurner B, et al
    Tumor-Reactive CD4+ T Cell Responses to the Melanoma-Associated Chondroitin Sulphate Proteoglycan in Melanoma Patients and Healthy Individuals in the Absence of Autoimmunity.
    J Immunol. 2007;178:7703-7709.
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32. MENDOZA-NARANJO A , Saez PJ, Johansson CC, Ramirez M, et al
    Functional Gap Junctions Facilitate Melanoma Antigen Transfer and Cross-Presentation between Human Dendritic Cells.
    J Immunol. 2007;178:6949-57.
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33. MICHALEK J , Kocak I, Fait V, Zaloudik J, et al
    Detection and long-term in vivo monitoring of individual tumor-specific T cell clones in patients with metastatic melanoma.
    J Immunol. 2007;178:6789-95.
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34. SUCIU-FOCA N , Feirt N, Zhang QY, Vlad G, et al
    Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients.
    J Immunol. 2007;178:7432-41.
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35. MUNKS MW , Pinto AK, Doom CM, Hill AB, et al
    Viral interference with antigen presentation does not alter acute or chronic CD8 T cell immunodominance in murine cytomegalovirus infection.
    J Immunol. 2007;178:7235-41.
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36. YU S , Liu C, Su K, Wang J, et al
    Tumor exosomes inhibit differentiation of bone marrow dendritic cells.
    J Immunol. 2007;178:6867-75.
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37. KRYCZEK I , Wei S, Zou L, Altuwaijri S, et al
    Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment.
    J Immunol. 2007;178:6730-3.
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    May 2007
38. HE LZ , Crocker A, Lee J, Mendoza-Ramirez J, et al
    Antigenic targeting of the human mannose receptor induces tumor immunity.
    J Immunol. 2007;178:6259-67.
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39. OKAJO J , Kaneko Y, Murata Y, Tomizawa T, et al
    Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of alpha-galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells.
    J Immunol. 2007;178:6164-72.
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    April 2007
40. GALILI U , Wigglesworth K, Abdel-Motal UM
    Intratumoral Injection of {alpha}-gal Glycolipids Induces Xenograft-Like Destruction and Conversion of Lesions into Endogenous Vaccines.
    J Immunol. 2007;178:4676-87.
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    March 2007
41. BARBEY C , Baumgaertner P, Devevre E, Rubio-Godoy V, et al
    IL-12 controls cytotoxicity of a novel subset of self-antigen-specific human CD28+ cytolytic T cells.
    J Immunol. 2007;178:3566-74.
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42. VAN DER BRUGGEN P , Traversari C, Chomez P, Lurquin C, et al
    Pillars article: a gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 1991. 254: 1643-1647.
    J Immunol. 2007;178:2617-21.
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    December 2006
43. PRINS RM , Vo DD, Khan-Farooqi H, Yang MY, et al
    NK and CD4 Cells Collaborate to Protect against Melanoma Tumor Formation in the Brain.
    J Immunol. 2006;177:8448-55.
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44. KOCHENDERFER JN , Chien CD, Simpson JL, Gress RE, et al
    Synergism between CpG-Containing Oligodeoxynucleotides and IL-2 Causes Dramatic Enhancement of Vaccine-Elicited CD8+ T Cell Responses.
    J Immunol. 2006;177:8860-73.
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45. WALTON SM , Gerlinger M, de la Rosa O, Nuber N, et al
    Spontaneous CD8 T Cell Responses against the Melanocyte Differentiation Antigen RAB38/NY-MEL-1 in Melanoma Patients.
    J Immunol. 2006;177:8212-8.
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    November 2006
46. BIOLEY G , Jandus C, Tuyaerts S, Rimoldi D, et al
    Melan-A/MART-1-Specific CD4 T Cells in Melanoma Patients: Identification of New Epitopes and Ex Vivo Visualization of Specific T Cells by MHC Class II Tetramers.
    J Immunol. 2006;177:6769-79.
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47. HONG C , Lee H, Oh M, Kang CY, et al
    CD4+ T cells in the absence of the CD8+ cytotoxic T cells are critical and sufficient for NKT cell-dependent tumor rejection.
    J Immunol. 2006;177:6747-57.
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48. POWELL DJ JR , Dudley ME, Hogan KA, Wunderlich JR, et al
    Adoptive Transfer of Vaccine-Induced Peripheral Blood Mononuclear Cells to Patients with Metastatic Melanoma following Lymphodepletion.
    J Immunol. 2006;177:6527-39.
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49. JOHNSON LA , Heemskerk B, Powell DJ Jr, Cohen CJ, et al
    Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes.
    J Immunol. 2006;177:6548-59.
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50. HARGADON KM , Brinkman CC, Sheasley-O'neill SL, Nichols LA, et al
    Incomplete differentiation of antigen-specific CD8 T cells in tumor-draining lymph nodes.
    J Immunol. 2006;177:6081-90.
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51. STOKLASEK TA , Schluns KS, Lefrancois L
    Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo.
    J Immunol. 2006;177:6072-80.
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52. MARKEL G , Seidman R, Stern N, Cohen-Sinai T, et al
    Inhibition of human tumor-infiltrating lymphocyte effector functions by the homophilic carcinoembryonic cell adhesion molecule 1 interactions.
    J Immunol. 2006;177:6062-71.
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    September 2006
53. SANCHEZ-PEREZ L , Kottke T, Daniels GA, Diaz RM, et al
    Killing of Normal Melanocytes, Combined with Heat Shock Protein 70 and CD40L Expression, Cures Large Established Melanomas.
    J Immunol. 2006;177:4168-77.
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54. PERALES MA , Diab A, Cohen AD, Huggins DW, et al
    DNA Immunization against Tissue-Restricted Antigens Enhances Tumor Immunity after Allogeneic Hemopoietic Stem Cell Transplantation.
    J Immunol. 2006;177:4159-67.
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55. SHIBATA S , Okano S, Yonemitsu Y, Onimaru M, et al
    Induction of efficient antitumor immunity using dendritic cells activated by recombinant Sendai virus and its modulation by exogenous IFN-beta gene.
    J Immunol. 2006;177:3564-76.
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56. DERRE L , Corvaisier M, Charreau B, Moreau A, et al
    Expression and Release of HLA-E by Melanoma Cells and Melanocytes: Potential Impact on the Response of Cytotoxic Effector Cells.
    J Immunol. 2006;177:3100-7.
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    August 2006
57. JANJIC B , Andrade P, Wang XF, Fourcade J, et al
    Spontaneous CD4+ T Cell Responses against TRAG-3 in Patients with Melanoma and Breast Cancers.
    J Immunol. 2006;177:2717-27.
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58. CHIANG EY , Stroynowski I
    The role of structurally conserved class I MHC in tumor rejection: contribution of the Q8 locus.
    J Immunol. 2006;177:2123-30.
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59. APPAY V , Jandus C, Voelter V, Reynard S, et al
    New Generation Vaccine Induces Effective Melanoma-Specific CD8+ T Cells in the Circulation but Not in the Tumor Site.
    J Immunol. 2006;177:1670-8.
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60. WANG XY , Arnouk H, Chen X, Kazim L, et al
    Extracellular targeting of endoplasmic reticulum chaperone glucose-regulated protein 170 enhances tumor immunity to a poorly immunogenic melanoma.
    J Immunol. 2006;177:1543-51.
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    July 2006
61. SPEISER DE , Baumgaertner P, Barbey C, Rubio-Godoy V, et al
    A novel approach to characterize clonality and differentiation of human melanoma-specific T cell responses: spontaneous priming and efficient boosting by vaccination.
    J Immunol. 2006;177:1338-48.
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62. WILLEMSEN RA , Sebestyen Z, Ronteltap C, Berrevoets C, et al
    CD8{alpha} Coreceptor to Improve TCR Gene Transfer to Treat Melanoma: Down-Regulation of Tumor-Specific Production of IL-4, IL-5, and IL-10.
    J Immunol. 2006;177:991-8.
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63. ZOETEWEIJ JP , Epperson DE, Porter JD, Zhang CX, et al
    GM1 binding-deficient exotoxin is a potent noninflammatory broad spectrum intradermal immunoadjuvant.
    J Immunol. 2006;177:1197-207.
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64. KAMIMURA D , Sawa Y, Sato M, Agung E, et al
    IL-2 In Vivo Activities and Antitumor Efficacy Enhanced by an Anti-IL-2 mAb.
    J Immunol. 2006;177:306-14.
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65. MCWILLIAMS JA , McGurran SM, Dow SW, Slansky JE, et al
    A modified tyrosinase-related protein 2 epitope generates high-affinity tumor-specific T cells but does not mediate therapeutic efficacy in an intradermal tumor model.
    J Immunol. 2006;177:155-61.
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    June 2006
66. HUANG J , Kerstann KW, Ahmadzadeh M, Li YF, et al
    Modulation by IL-2 of CD70 and CD27 expression on CD8+ T cells: importance for the therapeutic effectiveness of cell transfer immunotherapy.
    J Immunol. 2006;176:7726-35.
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67. SATO A , Ohtsuki M, Hata M, Kobayashi E, et al
    Antitumor activity of IFN-lambda in murine tumor models.
    J Immunol. 2006;176:7686-94.
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68. ZAKS K , Jordan M, Guth A, Sellins K, et al
    Efficient Immunization and Cross-Priming by Vaccine Adjuvants Containing TLR3 or TLR9 Agonists Complexed to Cationic Liposomes.
    J Immunol. 2006;176:7335-45.
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69. SHIMIZU M , Shimamura M, Owaki T, Asakawa M, et al
    Antiangiogenic and antitumor activities of IL-27.
    J Immunol. 2006;176:7317-24.
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70. PURBHOO MA , Sutton DH, Brewer JE, Mullings RE, et al
    Quantifying and imaging NY-ESO-1/LAGE-1-derived epitopes on tumor cells using high affinity T cell receptors.
    J Immunol. 2006;176:7308-16.
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71. RAMIREZ-MONTAGUT T , Chow A, Hirschhorn-Cymerman D, Terwey TH, et al
    Glucocorticoid-Induced TNF Receptor Family Related Gene Activation Overcomes Tolerance/Ignorance to Melanoma Differentiation Antigens and Enhances Antitumor Immunity.
    J Immunol. 2006;176:6434-6442.
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72. NISHIOKA T , Shimizu J, Iida R, Yamazaki S, et al
    CD4+CD25+Foxp3+ T cells and CD4+CD25-Foxp3+ T cells in aged mice.
    J Immunol. 2006;176:6586-93.
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73. COLOMBETTI S , Fagerberg T, Baumgartner P, Chapatte L, et al
    Impact of orthologous melan-A peptide immunizations on the anti-self melan-A/HLA-A2 T cell cross-reactivity.
    J Immunol. 2006;176:6560-7.
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74. HASAN L , Mazzucchelli L, Liebi M, Lis M, et al
    Function of liver activation-regulated chemokine/CC chemokine ligand 20 is differently affected by cathepsin B and cathepsin D processing.
    J Immunol. 2006;176:6512-22.
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    May 2006
75. LUO W , Ko E, Hsu JC, Wang X, et al
    Targeting melanoma cells with human high molecular weight-melanoma associated antigen-specific antibodies elicited by a Peptide mimotope: functional effects.
    J Immunol. 2006;176:6046-54.
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    April 2006
76. FRUCI D , Ferracuti S, Limongi MZ, Cunsolo V, et al
    Expression of Endoplasmic Reticulum Aminopeptidases in EBV-B Cell Lines from Healthy Donors and in Leukemia/Lymphoma, Carcinoma, and Melanoma Cell Lines.
    J Immunol. 2006;176:4869-79.
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77. MANJILI MH , Kmieciak M, Keeler J
    Comment on "Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8+ T Cells in Patients with Melanoma".
    J Immunol. 2006;176:4511.
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78. ROSENBERG SA , Restifo NP
    Response to Comment on "Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8+ T Cells in Patients with Melanoma".
    J Immunol. 2006;176:4511-2.
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79. SCHUMACHER LY , Vo DD, Garban HJ, Comin-Anduix B, et al
    Immunosensitization of tumor cells to dendritic cell-activated immune responses with the proteasome inhibitor bortezomib (PS-341, Velcade).
    J Immunol. 2006;176:4757-65.
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80. SCHUURHUIS DH , van Montfoort N, Ioan-Facsinay A, Jiawan R, et al
    Immune complex-loaded dendritic cells are superior to soluble immune complexes as antitumor vaccine.
    J Immunol. 2006;176:4573-80.
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81. MULLINS DW , Engelhard VH
    Limited infiltration of exogenous dendritic cells and naive T cells restricts immune responses in peripheral lymph nodes.
    J Immunol. 2006;176:4535-42.
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82. EBERT LM , Meuter S, Moser B
    Homing and function of human skin gammadelta T cells and NK cells: relevance for tumor surveillance.
    J Immunol. 2006;176:4331-6.
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    March 2006
83. TAIEB J , Chaput N, Schartz N, Roux S, et al
    Chemoimmunotherapy of tumors: cyclophosphamide synergizes with exosome based vaccines.
    J Immunol. 2006;176:2722-9.
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    February 2006
84. SMYTH MJ , Teng MW, Swann J, Kyparissoudis K, et al
    CD4+CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer.
    J Immunol. 2006;176:1582-7.
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85. DOLAN BP , Gibbs KD Jr, Ostrand-Rosenberg S
    Tumor-Specific CD4+ T Cells Are Activated by "Cross-Dressed" Dendritic Cells Presenting Peptide-MHC Class II Complexes Acquired from Cell-Based Cancer Vaccines.
    J Immunol. 2006;176:1447-55.
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86. GENG H , Zhang GM, Li D, Zhang H, et al
    Soluble form of T cell Ig mucin 3 is an inhibitory molecule in T cell-mediated immune response.
    J Immunol. 2006;176:1411-20.
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87. GRUNDEMANN C , Bauer M, Schweier O, von Oppen N, et al
    Cutting edge: identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1.
    J Immunol. 2006;176:1311-5.
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    December 2005
88. SMITH CL , Mirza F, Pasquetto V, Tscharke DC, et al
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