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  Malignant Melanoma

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Articles published in J Immunol

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    March 2010
  1. GARCIA-HERNANDEZ MD , Hamada H, Reome JB, Misra SK, et al
    Adoptive Transfer of Tumor-Specific Tc17 Effector T Cells Controls the Growth of B16 Melanoma in Mice.
    J Immunol. 2010.
    PubMed     Text format     Related articles    Abstract available


  2. DILILLO DJ , Yanaba K, Tedder TF
    B Cells Are Required for Optimal CD4+ and CD8+ T Cell Tumor Immunity: Therapeutic B Cell Depletion Enhances B16 Melanoma Growth in Mice.
    J Immunol. 2010.
    PubMed     Text format     Related articles    Abstract available


  3. PILON-THOMAS S , Mackay A, Vohra N, Mule JJ, et al
    Blockade of Programmed Death Ligand 1 Enhances the Therapeutic Efficacy of Combination Immunotherapy against Melanoma.
    J Immunol. 2010.
    PubMed     Text format     Related articles    Abstract available


    February 2010
  4. WANG Y , Cella M, Gilfillan S, Colonna M, et al
    Cutting Edge: Polyinosinic:Polycytidylic Acid Boosts the Generation of Memory CD8 T Cells through Melanoma Differentiation-Associated Protein 5 Expressed in Stromal Cells.
    J Immunol. 2010.
    PubMed     Text format     Related articles    Abstract available


  5. DIETL K , Renner K, Dettmer K, Timischl B, et al
    Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes.
    J Immunol. 2010;184:1200-9.
    PubMed     Text format     Related articles    Abstract available


  6. DIAO J , Zhao J, Winter E, Cattral MS, et al
    Recruitment and differentiation of conventional dendritic cell precursors in tumors.
    J Immunol. 2010;184:1261-7.
    PubMed     Text format     Related articles    Abstract available


  7. LUNDQVIST A , Su S, Rao S, Childs R, et al
    Cutting edge: bortezomib-treated tumors sensitized to NK cell apoptosis paradoxically acquire resistance to antigen-specific T cells.
    J Immunol. 2010;184:1139-42.
    PubMed     Text format     Related articles    Abstract available


  8. SU X , Ye J, Hsueh EC, Zhang Y, et al
    Tumor microenvironments direct the recruitment and expansion of human Th17 cells.
    J Immunol. 2010;184:1630-41.
    PubMed     Text format     Related articles    Abstract available


    January 2010
  9. WATCHMAKER PB , Berk E, Muthuswamy R, Mailliard RB, et al
    Independent regulation of chemokine responsiveness and cytolytic function versus CD8+ T cell expansion by dendritic cells.
    J Immunol. 2010;184:591-7.
    PubMed     Text format     Related articles    Abstract available


  10. CUFF S , Dolton G, Matthews RJ, Gallimore A, et al
    Antigen specificity determines the pro- or antitumoral nature of CD8+ T cells.
    J Immunol. 2010;184:607-14.
    PubMed     Text format     Related articles    Abstract available


  11. BUCHAU AS , Morizane S, Trowbridge J, Schauber J, et al
    The host defense peptide cathelicidin is required for NK cell-mediated suppression of tumor growth.
    J Immunol. 2010;184:369-78.
    PubMed     Text format     Related articles    Abstract available


    December 2009
  12. CHAN CJ , Andrews DM, McLaughlin NM, Yagita H, et al
    DNAM-1/CD155 Interactions Promote Cytokine and NK Cell-Mediated Suppression of Poorly Immunogenic Melanoma Metastases.
    J Immunol. 2009.
    PubMed     Text format     Related articles    Abstract available


    November 2009
  13. LI Y , Liu S, Hernandez J, Vence L, et al
    MART-1-Specific Melanoma Tumor-Infiltrating Lymphocytes Maintaining CD28 Expression Have Improved Survival and Expansion Capability Following Antigenic Restimulation In Vitro.
    J Immunol. 2009.
    PubMed     Text format     Related articles    Abstract available


  14. HAN L , Wang W, Fang Y, Feng Z, et al
    Soluble B and T Lymphocyte Attenuator Possesses Antitumor Effects and Facilitates Heat Shock Protein 70 Vaccine-Triggered Antitumor Immunity against a Murine TC-1 Cervical Cancer Model In Vivo.
    J Immunol. 2009.
    PubMed     Text format     Related articles    Abstract available


    October 2009
  15. KIMPFLER S , Sevko A, Ring S, Falk C, et al
    Skin Melanoma Development in ret Transgenic Mice Despite the Depletion of CD25+Foxp3+ Regulatory T Cells in Lymphoid Organs.
    J Immunol. 2009.
    PubMed     Text format     Related articles    Abstract available


  16. STARR R , Fuchsberger M, Lau LS, Uldrich AP, et al
    SOCS-1 binding to tyrosine 441 of IFN-gamma receptor subunit 1 contributes to the attenuation of IFN-gamma signaling in vivo.
    J Immunol. 2009;183:4537-44.
    PubMed     Text format     Related articles    Abstract available


  17. PRESTWICH RJ , Errington F, Steele LP, Ilett EJ, et al
    Reciprocal human dendritic cell-natural killer cell interactions induce antitumor activity following tumor cell infection by oncolytic reovirus.
    J Immunol. 2009;183:4312-21.
    PubMed     Text format     Related articles    Abstract available


    September 2009
  18. WIECKOWSKI S , Baumgaertner P, Corthesy P, Voelter V, et al
    Fine Structural Variations of {alpha}{beta}TCRs Selected by Vaccination with Natural versus Altered Self-Antigen in Melanoma Patients.
    J Immunol. 2009.
    PubMed     Text format     Related articles    Abstract available


  19. WIECKOWSKI EU , Visus C, Szajnik M, Szczepanski MJ, et al
    Tumor-derived microvesicles promote regulatory T cell expansion and induce apoptosis in tumor-reactive activated CD8+ T lymphocytes.
    J Immunol. 2009;183:3720-30.
    PubMed     Text format     Related articles    Abstract available


  20. LI Q , Teitz-Tennenbaum S, Donald EJ, Li M, et al
    In vivo sensitized and in vitro activated B cells mediate tumor regression in cancer adoptive immunotherapy.
    J Immunol. 2009;183:3195-203.
    PubMed     Text format     Related articles    Abstract available


    August 2009
  21. MIYAKE T , Kumagai Y, Kato H, Guo Z, et al
    Poly I:C-induced activation of NK cells by CD8 alpha+ dendritic cells via the IPS-1 and TRIF-dependent pathways.
    J Immunol. 2009;183:2522-8.
    PubMed     Text format     Related articles    Abstract available


    July 2009
  22. GONG J , Zhu B, Murshid A, Adachi H, et al
    T Cell Activation by Heat Shock Protein 70 Vaccine Requires TLR Signaling and Scavenger Receptor Expressed by Endothelial Cells-1.
    J Immunol. 2009.
    PubMed     Text format     Related articles    Abstract available


  23. RODRIGUEZ-GALAN MC , Reynolds D, Correa SG, Iribarren P, et al
    Coexpression of IL-18 strongly attenuates IL-12-induced systemic toxicity through a rapid induction of IL-10 without affecting its antitumor capacity.
    J Immunol. 2009;183:740-8.
    PubMed     Text format     Related articles    Abstract available


    June 2009
  24. SIKORA AG , Jaffarzad N, Hailemichael Y, Gelbard A, et al
    IFN-alpha enhances peptide vaccine-induced CD8+ T cell numbers, effector function, and antitumor activity.
    J Immunol. 2009;182:7398-407.
    PubMed     Text format     Related articles    Abstract available


    May 2009
  25. MICHAELI Y , Denkberg G, Sinik K, Lantzy L, et al
    Expression hierarchy of T cell epitopes from melanoma differentiation antigens: unexpected high level presentation of tyrosinase-HLA-A2 Complexes revealed by peptide-specific, MHC-restricted, TCR-like antibodies.
    J Immunol. 2009;182:6328-41.
    PubMed     Text format     Related articles    Abstract available


  26. ANZ D , Thaler R, Stephan N, Waibler Z, et al
    Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus.
    J Immunol. 2009;182:6044-50.
    PubMed     Text format     Related articles    Abstract available


  27. LIU Y , Peng Y, Mi M, Guevara-Patino J, et al
    Lentivector immunization stimulates potent CD8 T cell responses against melanoma self-antigen tyrosinase-related protein 1 and generates antitumor immunity in mice.
    J Immunol. 2009;182:5960-9.
    PubMed     Text format     Related articles    Abstract available


  28. FOURCADE J , Kudela P, Sun Z, Shen H, et al
    PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients.
    J Immunol. 2009;182:5240-9.
    PubMed     Text format     Related articles    Abstract available


    April 2009
  29. OSTANKOVITCH M , Altrich-Vanlith M, Robila V, Engelhard VH, et al
    N-glycosylation enhances presentation of a MHC class I-restricted epitope from tyrosinase.
    J Immunol. 2009;182:4830-5.
    PubMed     Text format     Related articles    Abstract available


  30. LOHMANN C , Muschaweckh A, Kirschnek S, Jennen L, et al
    Induction of tumor cell apoptosis or necrosis by conditional expression of cell death proteins: analysis of cell death pathways and in vitro immune stimulatory potential.
    J Immunol. 2009;182:4538-46.
    PubMed     Text format     Related articles    Abstract available


    March 2009
  31. ERIKSSON F , Tsagozis P, Lundberg K, Parsa R, et al
    Tumor-specific bacteriophages induce tumor destruction through activation of tumor-associated macrophages.
    J Immunol. 2009;182:3105-11.
    PubMed     Text format     Related articles    Abstract available


  32. PAREKH VV , Lalani S, Kim S, Halder R, et al
    PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells.
    J Immunol. 2009;182:2816-26.
    PubMed     Text format     Related articles    Abstract available


  33. FRLETA D , Yu CI, Klechevsky E, Flamar AL, et al
    Influenza virus and poly(I:C) inhibit MHC class I-restricted presentation of cell-associated antigens derived from infected dead cells captured by human dendritic cells.
    J Immunol. 2009;182:2766-76.
    PubMed     Text format     Related articles    Abstract available


  34. GERNER MY , Mescher MF
    Antigen processing and MHC-II presentation by dermal and tumor-infiltrating dendritic cells.
    J Immunol. 2009;182:2726-37.
    PubMed     Text format     Related articles    Abstract available


  35. BENLALAM H , Jalil A, Hasmim M, Pang B, et al
    Gap junction communication between autologous endothelial and tumor cells induce cross-recognition and elimination by specific CTL.
    J Immunol. 2009;182:2654-64.
    PubMed     Text format     Related articles    Abstract available


    February 2009
  36. YAGIL Z , Kay G, Nechushtan H, Razin E, et al
    A specific epitope of protein inhibitor of activated STAT3 is responsible for the induction of apoptosis in rat transformed mast cells.
    J Immunol. 2009;182:2168-75.
    PubMed     Text format     Related articles    Abstract available


  37. SALEM ML , Diaz-Montero CM, Al-Khami AA, El-Naggar SA, et al
    Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C).
    J Immunol. 2009;182:2030-40.
    PubMed     Text format     Related articles    Abstract available


  38. PAGET C , Bialecki E, Fontaine J, Vendeville C, et al
    Role of invariant NK T lymphocytes in immune responses to CpG oligodeoxynucleotides.
    J Immunol. 2009;182:1846-53.
    PubMed     Text format     Related articles    Abstract available


  39. HEMMI H , Idoyaga J, Suda K, Suda N, et al
    A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells.
    J Immunol. 2009;182:1278-86.
    PubMed     Text format     Related articles    Abstract available


  40. DICKGREBER N , Stoitzner P, Bai Y, Price KM, et al
    Targeting antigen to MHC class II molecules promotes efficient cross-presentation and enhances immunotherapy.
    J Immunol. 2009;182:1260-9.
    PubMed     Text format     Related articles    Abstract available


    January 2009
  41. WOLF AI , Buehler D, Hensley SE, Cavanagh LL, et al
    Plasmacytoid dendritic cells are dispensable during primary influenza virus infection.
    J Immunol. 2009;182:871-9.
    PubMed     Text format     Related articles    Abstract available


  42. KAWAMURA T , Takeda K, Kaneda H, Matsumoto H, et al
    NKG2A inhibits invariant NKT cell activation in hepatic injury.
    J Immunol. 2009;182:250-8.
    PubMed     Text format     Related articles    Abstract available


  43. UMESHAPPA CS , Huang H, Xie Y, Wei Y, et al
    CD4+ Th-APC with acquired peptide/MHC class I and II complexes stimulate type 1 helper CD4+ and central memory CD8+ T cell responses.
    J Immunol. 2009;182:193-206.
    PubMed     Text format     Related articles    Abstract available


  44. HAN Y , Guo Q, Zhang M, Chen Z, et al
    CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1.
    J Immunol. 2009;182:111-20.
    PubMed     Text format     Related articles    Abstract available


    December 2008
  45. ROBILA V , Ostankovitch M, Altrich-Vanlith ML, Theos AC, et al
    MHC Class II Presentation of gp100 Epitopes in Melanoma Cells Requires the Function of Conventional Endosomes and Is Influenced by Melanosomes.
    J Immunol. 2008;181:7843-7852.
    PubMed     Text format     Related articles    Abstract available


  46. RADHAKRISHNAN S , Arneson LN, Upshaw JL, Howe CL, et al
    TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells.
    J Immunol. 2008;181:7863-72.
    PubMed     Text format     Related articles    Abstract available


    November 2008
  47. SAUER KA , Maxeiner JH, Karwot R, Scholtes P, et al
    Immunosurveillance of lung melanoma metastasis in EBI-3-deficient mice mediated by CD8+ T cells.
    J Immunol. 2008;181:6148-57.
    PubMed     Text format     Related articles    Abstract available


  48. HIMOUDI N , Nabarro S, Buddle J, Eddaoudi A, et al
    Bone marrow-derived IFN-producing killer dendritic cells account for the tumoricidal activity of unpulsed dendritic cells.
    J Immunol. 2008;181:6654-63.
    PubMed     Text format     Related articles    Abstract available


  49. WIERZBICKI A , Gil M, Ciesielski M, Fenstermaker RA, et al
    Immunization with a mimotope of GD2 ganglioside induces CD8+ T cells that recognize cell adhesion molecules on tumor cells.
    J Immunol. 2008;181:6644-53.
    PubMed     Text format     Related articles    Abstract available


  50. SKOLD M , Behar SM
    Tuberculosis triggers a tissue-dependent program of differentiation and acquisition of effector functions by circulating monocytes.
    J Immunol. 2008;181:6349-60.
    PubMed     Text format     Related articles    Abstract available


    October 2008
  51. DE WITTE MA , Jorritsma A, Kaiser A, van den Boom MD, et al
    Requirements for effective antitumor responses of TCR transduced T cells.
    J Immunol. 2008;181:5128-36.
    PubMed     Text format     Related articles    Abstract available


    September 2008
  52. WELLS JW , Cowled CJ, Farzaneh F, Noble A, et al
    Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity.
    J Immunol. 2008;181:3422-31.
    PubMed     Text format     Related articles    Abstract available


    August 2008
  53. MORENO M , Molling JW, von Mensdorff-Pouilly S, Verheijen RH, et al
    IFN-gamma-producing human invariant NKT cells promote tumor-associated antigen-specific cytotoxic T cell responses.
    J Immunol. 2008;181:2446-54.
    PubMed     Text format     Related articles    Abstract available


    July 2008
  54. CHHABRA A , Yang L, Wang P, Comin-Anduix B, et al
    CD4+CD25- T Cells Transduced to Express MHC Class I-Restricted Epitope-Specific TCR Synthesize Th1 Cytokines and Exhibit MHC Class I-Restricted Cytolytic Effector Function in a Human Melanoma Model.
    J Immunol. 2008;181:1063-70.
    PubMed     Text format     Related articles    Abstract available


  55. ADAMS S , O'Neill DW, Nonaka D, Hardin E, et al
    Immunization of Malignant Melanoma Patients with Full-Length NY-ESO-1 Protein Using TLR7 Agonist Imiquimod as Vaccine Adjuvant.
    J Immunol. 2008;181:776-84.
    PubMed     Text format     Related articles    Abstract available


    June 2008
  56. WERNECK MB , Lugo-Villarino G, Hwang ES, Cantor H, et al
    T-Bet Plays a Key Role in NK-Mediated Control of Melanoma Metastatic Disease.
    J Immunol. 2008;180:8004-10.
    PubMed     Text format     Related articles    Abstract available


  57. ULLRICH E , Bonmort M, Mignot G, Jacobs B, et al
    Trans-presentation of IL-15 dictates IFN-producing killer dendritic cells effector functions.
    J Immunol. 2008;180:7887-97.
    PubMed     Text format     Related articles    Abstract available


  58. SHIME H , Yabu M, Akazawa T, Kodama K, et al
    Tumor-secreted lactic acid promotes IL-23/IL-17 proinflammatory pathway.
    J Immunol. 2008;180:7175-83.
    PubMed     Text format     Related articles    Abstract available


    May 2008
  59. YOSHIMOTO T , Morishima N, Mizoguchi I, Shimizu M, et al
    Antiproliferative Activity of IL-27 on Melanoma.
    J Immunol. 2008;180:6527-35.
    PubMed     Text format     Related articles    Abstract available


    April 2008
  60. FUERTES MB , Girart MV, Molinero LL, Domaica CI, et al
    Intracellular Retention of the NKG2D Ligand MHC Class I Chain-Related Gene A in Human Melanomas Confers Immune Privilege and Prevents NK Cell-Mediated Cytotoxicity.
    J Immunol. 2008;180:4606-14.
    PubMed     Text format     Related articles    Abstract available


    March 2008
  61. HALLERMALM K , Seki K, De Geer A, Motyka B, et al
    Modulation of the Tumor Cell Phenotype by IFN-{gamma} Results in Resistance of Uveal Melanoma Cells to Granule-Mediated Lysis by Cytotoxic Lymphocytes.
    J Immunol. 2008;180:3766-74.
    PubMed     Text format     Related articles    Abstract available


  62. JARNICKI AG , Conroy H, Brereton C, Donnelly G, et al
    Attenuating Regulatory T Cell Induction by TLR Agonists through Inhibition of p38 MAPK Signaling in Dendritic Cells Enhances Their Efficacy as Vaccine Adjuvants and Cancer Immunotherapeutics.
    J Immunol. 2008;180:3797-806.
    PubMed     Text format     Related articles    Abstract available


  63. CARRASCO J , Van Pel A, Neyns B, Lethe B, et al
    Vaccination of a Melanoma Patient with Mature Dendritic Cells Pulsed with MAGE-3 Peptides Triggers the Activity of Nonvaccine Anti-Tumor Cells.
    J Immunol. 2008;180:3585-93.
    PubMed     Text format     Related articles    Abstract available


  64. STRAUSS L , Bergmann C, Szczepanski MJ, Lang S, et al
    Expression of ICOS on Human Melanoma-Infiltrating CD4+CD25highFoxp3+ T Regulatory Cells: Implications and Impact on Tumor-Mediated Immune Suppression.
    J Immunol. 2008;180:2967-80.
    PubMed     Text format     Related articles    Abstract available


  65. HOLST PJ , Sorensen MR, Mandrup Jensen CM, Orskov C, et al
    MHC Class II-Associated Invariant Chain Linkage of Antigen Dramatically Improves Cell-Mediated Immunity Induced by Adenovirus Vaccines.
    J Immunol. 2008;180:3339-46.
    PubMed     Text format     Related articles    Abstract available


  66. LUGADE AA , Sorensen EW, Gerber SA, Moran JP, et al
    Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity.
    J Immunol. 2008;180:3132-9.
    PubMed     Text format     Related articles    Abstract available


    February 2008
  67. DUBOIS S , Patel HJ, Zhang M, Waldmann TA, et al
    Preassociation of IL-15 with IL-15R alpha-IgG1-Fc enhances its activity on proliferation of NK and CD8+/CD44high T cells and its antitumor action.
    J Immunol. 2008;180:2099-106.
    PubMed     Text format     Related articles    Abstract available


  68. STOITZNER P , Green LK, Jung JY, Price KM, et al
    Tumor immunotherapy by epicutaneous immunization requires langerhans cells.
    J Immunol. 2008;180:1991-8.
    PubMed     Text format     Related articles    Abstract available


    January 2008
  69. TORRES D , Paget C, Fontaine J, Mallevaey T, et al
    Prostaglandin D2 Inhibits the Production of IFN-{gamma} by Invariant NK T Cells: Consequences in the Control of B16 Melanoma.
    J Immunol. 2008;180:783-92.
    PubMed     Text format     Related articles    Abstract available   Free Full Text


  70. LENGAGNE R , Graff-Dubois S, Garcette M, Renia L, et al
    Distinct role for CD8 T cells toward cutaneous tumors and visceral metastases.
    J Immunol. 2008;180:130-7.
    PubMed     Text format     Related articles    Abstract available


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