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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Lung Cancer

Free Subscription Articles published in Oncogene Retrieve available abstracts of 73 articles: HTML format

Single Articles

May 2008
1. BINDA O , Nassif C, Branton PE
   SIRT1 negatively regulates HDAC1-dependent transcriptional repression by the RBP1 family of proteins.
   Oncogene. 2008;27:3384-92.
   PubMed     Related articles    Abstract available
   
   
   
2. KAPLAN-LEFKO PJ , Sutherland BW, Evangelou AI, Hadsell DL, et al
   Enforced epithelial expression of IGF-1 causes hyperplastic prostate growth while negative selection is requisite for spontaneous metastogenesis.
   Oncogene. 2008;27:2868-76.
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   April 2008
3. FREDERICK LA , Matthews JA, Jamieson L, Justilien V, et al
   Matrix metalloproteinase-10 is a critical effector of protein kinase Ciota-Par6alpha-mediated lung cancer.
   Oncogene. 2008;.
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4. JUNG H , Lee KP, Park SJ, Park JH, et al
   TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition.
   Oncogene. 2008;27:2635-47.
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5. LI D , Ambrogio L, Shimamura T, Kubo S, et al
   BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models.
   Oncogene. 2008;.
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6. OGIWARA H , Kohno T, Nakanishi H, Nagayama K, et al
   Unbalanced translocation, a major chromosome alteration causing loss of heterozygosity in human lung cancer.
   Oncogene. 2008;.
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   March 2008
7. CHEN Z , Feng J, Saldivar JS, Gu D, et al
   EGFR somatic doublets in lung cancer are frequent and generally arise from a pair of driver mutations uncommonly seen as singlet mutations: one-third of doublets occur at five pairs of amino acids.
   Oncogene. 2008;.
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   February 2008
8. WENDT MK , Cooper AN, Dwinell MB
   Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells.
   Oncogene. 2008;27:1461-71.
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9. SAFINA A , Ren MQ, Vandette E, Bakin AV, et al
   TAK1 is required for TGF-beta 1-mediated regulation of matrix metalloproteinase-9 and metastasis.
   Oncogene. 2008;27:1198-207.
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10. GAROFALO M , Quintavalle C, Di Leva G, Zanca C, et al
    MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer.
    Oncogene. 2008;.
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    January 2008
11. FALVELLA FS , Colombo F, Spinola M, Campiglio M, et al
    BHLHB3: a candidate tumor suppressor in lung cancer.
    Oncogene. 2008;.
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12. KWEI KA , Kim YH, Girard L, Kao J, et al
    Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer.
    Oncogene. 2008;.
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13. BORCZUK AC , Papanikolaou N, Toonkel RL, Sole M, et al
    Lung adenocarcinoma invasion in TGFbetaRII-deficient cells is mediated by CCL5/RANTES.
    Oncogene. 2008;27:557-64.
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14. RICHARD S , Vogel G, Huot ME, Guo T, et al
    Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis.
    Oncogene. 2008;27:548-56.
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15. CHEN Z , Li J, Li QS, Fan JQ, et al
    Suppression of PPN/MG61 attenuates Wnt/beta-catenin signaling pathway and induces apoptosis in human lung cancer.
    Oncogene. 2008;.
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16. MORIMOTO K , Satoh-Yamaguchi K, Hamaguchi A, Inoue Y, et al
    Interaction of cancer cells with platelets mediated by Necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs.
    Oncogene. 2008;27:264-73.
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    December 2007
17. SANCHEZ-CESPEDES M
    A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome.
    Oncogene. 2007;26:7825-32.
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18. HAJJI N , Wallenborg K, Vlachos P, Nyman U, et al
    Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells.
    Oncogene. 2007;.
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19. CHETTY C , Bhoopathi P, Lakka SS, Rao JS, et al
    MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
    Oncogene. 2007;26:7675-83.
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    November 2007
20. BRUTON RK , Rasti M, Mapp KL, Young N, et al
    C-terminal-binding protein interacting protein binds directly to adenovirus early region 1A through its N-terminal region and conserved region 3.
    Oncogene. 2007;26:7467-79.
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21. YANG HY , Wen YY, Lin YI, Pham L, et al
    Roles for negative cell regulator 14-3-3sigma in control of MDM2 activities.
    Oncogene. 2007;26:7355-62.
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22. SETHI G , Ahn KS, Chaturvedi MM, Aggarwal BB, et al
    Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha.
    Oncogene. 2007;26:7324-32.
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    October 2007
23. GLAROS S , Cirrincione GM, Muchardt C, Kleer CG, et al
    The reversible epigenetic silencing of BRM: implications for clinical targeted therapy.
    Oncogene. 2007;26:7058-66.
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24. FLINTERMAN MB , Mymryk JS, Klanrit P, Yousef AF, et al
    p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing.
    Oncogene. 2007;26:6863-74.
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25. SALON C , Merdzhanova G, Brambilla C, Brambilla E, et al
    E2F-1, Skp2 and cyclin E oncoproteins are upregulated and directly correlated in high-grade neuroendocrine lung tumors.
    Oncogene. 2007;26:6927-36.
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26. ROELLE S , Grosse R, Buech T, Chubanov V, et al
    Essential role of Pyk2 and Src kinase activation in neuropeptide-induced proliferation of small cell lung cancer cells.
    Oncogene. 2007;.
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27. GALLEGO MA , Ballot C, Kluza J, Hajji N, et al
    Overcoming chemoresistance of non-small cell lung carcinoma through restoration of an AIF-dependent apoptotic pathway.
    Oncogene. 2007;.
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    September 2007
28. COOPER WN , Dickinson RE, Dallol A, Grigorieva EV, et al
    Epigenetic regulation of the ras effector/tumour suppressor RASSF2 in breast and lung cancer.
    Oncogene. 2007;.
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29. XIAO W , Zhang Q, Habermacher G, Yang X, et al
    U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia.
    Oncogene. 2007;.
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30. MATSUBARA H , Takeuchi T, Nishikawa E, Yanagisawa K, et al
    Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92.
    Oncogene. 2007;26:6099-105.
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31. YANG L , Lin C, Sun SY, Zhao S, et al
    A double tyrosine phosphorylation of P68 RNA helicase confers resistance to TRAIL-induced apoptosis.
    Oncogene. 2007;26:6082-92.
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    August 2007
32. MATSUMOTO S , Iwakawa R, Takahashi K, Kohno T, et al
    Prevalence and specificity of LKB1 genetic alterations in lung cancers.
    Oncogene. 2007;26:5911-8.
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33. FALVELLA FS , Spinola M, Pignatiello C, Noci S, et al
    AZGP1 mRNA levels in normal human lung tissue correlate with lung cancer disease status.
    Oncogene. 2007;.
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34. RAMER R , Eichele K, Hinz B
    Upregulation of tissue inhibitor of matrix metalloproteinases-1 confers the anti-invasive action of cisplatin on human cancer cells.
    Oncogene. 2007;26:5822-7.
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35. KUSTERS B , Kats G, Roodink I, Verrijp K, et al
    Micronodular transformation as a novel mechanism of VEGF-A-induced metastasis.
    Oncogene. 2007;26:5808-15.
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    July 2007
36. KE Y , Wu D, Princen F, Nguyen T, et al
    Role of Gab2 in mammary tumorigenesis and metastasis.
    Oncogene. 2007;26:4951-60.
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37. FU YN , Yeh CL, Cheng HH, Yang CH, et al
    EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: implications in targeting therapy.
    Oncogene. 2007;.
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38. WU YH , Tsai Chang JH, Cheng YW, Wu TC, et al
    Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers.
    Oncogene. 2007;26:4761-73.
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39. PREET A , Ganju RK, Groopman JE
    Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo.
    Oncogene. 2007;.
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40. ANGELONI D , Danilkovitch-Miagkova A, Ivanova T, Braga E, et al
    Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter.
    Oncogene. 2007;26:4499-512.
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41. TOMIDA S , Yanagisawa K, Koshikawa K, Yatabe Y, et al
    Identification of a metastasis signature and the DLX4 homeobox protein as a regulator of metastasis by combined transcriptome approach.
    Oncogene. 2007;26:4600-8.
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    June 2007
42. HAASE D , Meister M, Muley T, Hess J, et al
    FRMD3, a novel putative tumour suppressor in NSCLC.
    Oncogene. 2007;26:4464-8.
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43. DESNOYERS LR , Pai R, Ferrando RE, Hotzel K, et al
    Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.
    Oncogene. 2007;.
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44. TAI KY , Shiah SG, Shieh YS, Kao YR, et al
    DNA methylation and histone modification regulate silencing of epithelial cell adhesion molecule for tumor invasion and progression.
    Oncogene. 2007;26:3989-97.
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45. LIN X , Morgan-Lappe S, Huang X, Li L, et al
    'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.
    Oncogene. 2007;26:3972-9.
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46. BARTKOVA J , Horej Sbreve I Z, Sehested M, Nesland JM, et al
    DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.
    Oncogene. 2007;.
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    May 2007
47. STINCHCOMBE TE , Socinski MA
    Bevacizumab in the treatment of non-small-cell lung cancer.
    Oncogene. 2007;26:3691-8.
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48. SOMMER P , Le Rouzic P, Gillingham H, Berry A, et al
    Glucocorticoid receptor overexpression exerts an antisurvival effect on human small cell lung cancer cells.
    Oncogene. 2007;.
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49. SHEPARD CR , Kassis J, Whaley DL, Kim HG, et al
    PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors.
    Oncogene. 2007;26:3020-6.
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50. ZHENG S , El-Naggar AK, Kim ES, Kurie JM, et al
    A genetic mouse model for metastatic lung cancer with gender differences in survival.
    Oncogene. 2007;.
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51. LIN J , Sun T, Ji L, Deng W, et al
    Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: inhibition of c-Abl by the tumor suppressor gene product Fus1.
    Oncogene. 2007;.
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52. SHTIEGMAN K , Kochupurakkal BS, Zwang Y, Pines G, et al
    Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.
    Oncogene. 2007;.
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    April 2007
53. SANO A , Kage H, Sugimoto K, Kitagawa H, et al
    A second-generation profiling system for quantitative methylation analysis of multiple gene promoters: application to lung cancer.
    Oncogene. 2007;.
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    March 2007
54. LIU H , Zhou Y, Boggs SE, Belinsky SA, et al
    Cigarette smoke induces demethylation of prometastatic oncogene synuclein-gamma in lung cancer cells by downregulation of DNMT3B.
    Oncogene. 2007;.
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55. IRMER D , Funk JO, Blaukat A
    EGFR kinase domain mutations - functional impact and relevance for lung cancer therapy.
    Oncogene. 2007;.
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    February 2007
56. MINAMI Y , Shimamura T, Shah K, Laframboise T, et al
    The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272.
    Oncogene. 2007;.
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57. WIKMAN H , Ruosaari S, Nymark P, Sarhadi VK, et al
    Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.
    Oncogene. 2007;.
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58. WU Y , McRoberts K, Berr SS, Frierson HF Jr, et al
    Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia.
    Oncogene. 2007;26:765-73.
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59. WU X , Shell SM, Liu Y, Zou Y, et al
    ATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiation.
    Oncogene. 2007;26:757-64.
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    January 2007
60. KANG Y , Hong JA, Chen GA, Nguyen DM, et al
    Dynamic transcriptional regulatory complexes including BORIS, CTCF and Sp1 modulate NY-ESO-1 expression in lung cancer cells.
    Oncogene. 2007;.
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61. CUI X , Zhang L, Luo J, Rajasekaran A, et al
    Unphosphorylated STAT6 contributes to constitutive cyclooxygenase-2 expression in human non-small cell lung cancer.
    Oncogene. 2007;.
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62. ZHANG YW , Staal B, Su Y, Swiatek P, et al
    Evidence that MIG-6 is a tumor-suppressor gene.
    Oncogene. 2007;26:269-76.
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63. NAGAI H , Sugito N, Matsubara H, Tatematsu Y, et al
    CLCP1 interacts with semaphorin 4B and regulates motility of lung cancer cells.
    Oncogene. 2007;.
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    November 2006
64. KO K , Furukawa K, Takahashi T, Urano T, et al
    Fundamental study of small interfering RNAs for ganglioside GD3 synthase gene as a therapeutic target of lung cancers.
    Oncogene. 2006;25:6924-35.
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    October 2006
65. KHATLANI TS , Wislez M, Sun M, Srinivas H, et al
    c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells.
    Oncogene. 2006;.
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66. ZHONG S , Fields CR, Su N, Pan YX, et al
    Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.
    Oncogene. 2006;.
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    September 2006
67. TOMKOVA K , El-Rifai W, Vilgelm A, Kelly MC, et al
    The gastrin gene promoter is regulated by p73 isoforms in tumor cells.
    Oncogene. 2006;25:6032-6.
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68. CARRAGHER NO , Walker SM, Scott Carragher LA, Harris F, et al
    Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function.
    Oncogene. 2006;25:5726-40.
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69. JACKSON-FISHER AJ , Bellinger G, Shum E, Duong JK, et al
    Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4.
    Oncogene. 2006;25:5664-72.
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    August 2006
70. SCAMBIA G , Lovergine S, Masciullo V
    RB family members as predictive and prognostic factors in human cancer.
    Oncogene. 2006;25:5302-8.
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71. CUEVAS BD , Winter-Vann AM, Johnson NL, Johnson GL, et al
    MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer.
    Oncogene. 2006;25:4998-5010.
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    July 2006
72. MITRA SK , Lim ST, Chi A, Schlaepfer DD, et al
    Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model.
    Oncogene. 2006;25:4429-40.
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    May 2006
73. CRUZ-MUNOZ W , Sanchez OH, Di Grappa M, English JL, et al
    Enhanced metastatic dissemination to multiple organs by melanoma and lymphoma cells in timp-3(-/-) mice.
    Oncogene. 2006;.
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