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Lung Cancer

Free Subscription Articles published in Clin Cancer Res Retrieve available abstracts of 148 articles: HTML format Text format

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March 2010
1. ROSS HJ , Blumenschein GR Jr, Aisner J, Damjanov N, et al
   Randomized Phase II Multicenter Trial of Two Schedules of Lapatinib as First- or Second-Line Monotherapy in Patients with Advanced or Metastatic Non-Small Cell Lung Cancer.
   Clin Cancer Res. 2010.
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   February 2010
2. HAMMER S , Sommer A, Fichtner I, Becker M, et al
   Comparative Profiling of the Novel Epothilone, Sagopilone, in Xenografts Derived from Primary Non-Small Cell Lung Cancer.
   Clin Cancer Res. 2010.
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3. GRZELINSKI M , Pinkenburg O, Buch T, Gold M, et al
   Critical Role of G{alpha}12 and G{alpha}13 for Human Small Cell Lung Cancer Cell Proliferation In vitro and Tumor Growth In vivo.
   Clin Cancer Res. 2010.
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4. KAMAL NS , Soria JC, Mendiboure J, Planchard D, et al
   MutS Homologue 2 and the Long-term Benefit of Adjuvant Chemotherapy in Lung Cancer.
   Clin Cancer Res. 2010.
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5. LEE DH , Park K, Kim JH, Lee JS, et al
   Randomized Phase III Trial of Gefitinib versus Docetaxel in Non-Small Cell Lung Cancer Patients Who Have Previously Received Platinum-Based Chemotherapy.
   Clin Cancer Res. 2010.
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6. WANG S , An T, Wang J, Zhao J, et al
   Potential Clinical Significance of a Plasma-Based KRAS Mutation Analysis in Patients with Advanced Non-Small Cell Lung Cancer.
   Clin Cancer Res. 2010.
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7. ZHANG M , Hu Z, Huang J, Shu Y, et al
   A 3'-Untranslated Region Polymorphism in IGF1 Predicts Survival of Non-Small Cell Lung Cancer in a Chinese Population.
   Clin Cancer Res. 2010.
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   January 2010
8. BISHOP JA , Benjamin H, Cholakh H, Chajut A, et al
   Accurate Classification of Non-Small Cell Lung Carcinoma Using a Novel MicroRNA-Based Approach.
   Clin Cancer Res. 2010.
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9. GIRARD N , Lou E, Azzoli CG, Reddy R, et al
   Analysis of Genetic Variants in Never-Smokers with Lung Cancer Facilitated by an Internet-Based Blood Collection Protocol: A Preliminary Report.
   Clin Cancer Res. 2010.
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10. BELEFORD D , Liu Z, Rattan R, Quagliuolo L, et al
    Methylation Induced Gene Silencing of HtrA3 in Smoking-Related Lung Cancer.
    Clin Cancer Res. 2010.
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11. LANDI MT , Zhao Y, Rotunno M, Koshiol J, et al
    MicroRNA Expression Differentiates Histology and Predicts Survival of Lung Cancer.
    Clin Cancer Res. 2010.
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    December 2009
12. GALIMBERTI F , Thompson SL, Liu X, Li H, et al
    Targeting the Cyclin E-Cdk-2 Complex Represses Lung Cancer Growth by Triggering Anaphase Catastrophe.
    Clin Cancer Res. 2009.
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13. BEHRENS C , Feng L, Kadara H, Kim HJ, et al
    Expression of Interleukin-1 Receptor-Associated Kinase-1 in Non-Small Cell Lung Carcinoma and Preneoplastic Lesions.
    Clin Cancer Res. 2009.
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14. BLUMENSCHEIN GR JR , Reckamp K, Stephenson GJ, O'Rourke T, et al
    Phase 1b Study of Motesanib, an Oral Angiogenesis Inhibitor, in Combination with Carboplatin/Paclitaxel and/or Panitumumab for the Treatment of Advanced Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2009.
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15. DAHABREH IJ , Linardou H, Siannis F, Kosmidis P, et al
    Somatic EGFR Mutation and Gene Copy Gain as Predictive Biomarkers for Response to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2009.
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16. HAMMERMAN PS , Janne PA, Johnson BE
    Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2009;15:7502-7509.
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17. YAMADA T , Matsumoto K, Wang W, Li Q, et al
    Hepatocyte Growth Factor Reduces Susceptibility to an Irreversible Epidermal Growth Factor Receptor Inhibitor in EGFR-T790M Mutant Lung Cancer.
    Clin Cancer Res. 2009.
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18. YOSHIZAWA A , Fukuoka J, Shimizu S, Shilo K, et al
    Overexpression of Phospho-eIF4E Is Associated with Survival through AKT Pathway in Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2009.
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    November 2009
19. HSU YC , Yuan S, Chen HY, Yu SL, et al
    A Four-Gene Signature from NCI-60 Cell Line for Survival Prediction in Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2009.
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20. SUNDARAM S , Trivedi R, Durairaj C, Ramesh R, et al
    Targeted Drug and Gene Delivery Systems for Lung Cancer Therapy.
    Clin Cancer Res. 2009.
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21. TANAKA F , Yoneda K, Kondo N, Hashimoto M, et al
    Circulating Tumor Cell as a Diagnostic Marker in Primary Lung Cancer.
    Clin Cancer Res. 2009.
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22. YANAGAWA J , Walser TC, Zhu LX, Hong L, et al
    Snail Promotes CXCR2 Ligand-Dependent Tumor Progression in Non-Small Cell Lung Carcinoma.
    Clin Cancer Res. 2009.
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    October 2009
23. BYERS LA , Sen B, Saigal B, Diao L, et al
    Reciprocal Regulation of c-Src and STAT3 in Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2009.
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24. WANG W , Li Q, Yamada T, Matsumoto K, et al
    Crosstalk to Stromal Fibroblasts Induces Resistance of Lung Cancer to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.
    Clin Cancer Res. 2009.
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    September 2009
25. RUDIN CM , Avila-Tang E, Harris CC, Herman JG, et al
    Lung cancer in never smokers: molecular profiles and therapeutic implications.
    Clin Cancer Res. 2009;15:5646-61.
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26. SAMET JM , Avila-Tang E, Boffetta P, Hannan LM, et al
    Lung cancer in never smokers: clinical epidemiology and environmental risk factors.
    Clin Cancer Res. 2009;15:5626-45.
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27. RUDIN CM , Avila-Tang E, Samet JM
    Lung cancer in never smokers: a call to action.
    Clin Cancer Res. 2009;15:5622-5.
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28. HU W , Hofstetter WL, Li H, Zhou Y, et al
    Putative Tumor-Suppressive Function of Kruppel-Like Factor 4 in Primary Lung Carcinoma.
    Clin Cancer Res. 2009.
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29. KRISHNASWAMY S , Kanteti R, Duke-Cohan JS, Loganathan S, et al
    Ethnic Differences and Functional Analysis of MET Mutations in Lung Cancer.
    Clin Cancer Res. 2009.
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    August 2009
30. PAO W , Kris MG, Iafrate AJ, Ladanyi M, et al
    Integration of Molecular Profiling into the Lung Cancer Clinic.
    Clin Cancer Res. 2009.
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31. WANG JC , Bierut LJ, Goate AM
    Variants Weakly Correlated with CHRNA5 D398N Polymorphism Should be Considered in Transcriptional Deregulation at the 15q25 Locus Associated with Lung Cancer Risk.
    Clin Cancer Res. 2009.
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32. HORN L , Sandler A
    Epidermal growth factor receptor inhibitors and antiangiogenic agents for the treatment of non-small cell lung cancer.
    Clin Cancer Res. 2009;15:5040-8.
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33. IWASA T , Okamoto I, Suzuki M, Hatashita E, et al
    Inhibition of insulin-like growth factor 1 receptor by CP-751,871 radiosensitizes non-small cell lung cancer cells.
    Clin Cancer Res. 2009;15:5117-25.
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34. JACKMAN DM , Miller VA, Cioffredi LA, Yeap BY, et al
    Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials.
    Clin Cancer Res. 2009;15:5267-73.
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35. MILLIGAN SA , Burke P, Coleman DT, Bigelow RL, et al
    The green tea polyphenol EGCG potentiates the antiproliferative activity of c-Met and epidermal growth factor receptor inhibitors in non-small cell lung cancer cells.
    Clin Cancer Res. 2009;15:4885-94.
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    July 2009
36. SUN M , Behrens C, Feng L, Ozburn N, et al
    HER Family Receptor Abnormalities in Lung Cancer Brain Metastases and Corresponding Primary Tumors.
    Clin Cancer Res. 2009.
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37. SCHMID K , Oehl N, Wrba F, Pirker R, et al
    EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases.
    Clin Cancer Res. 2009;15:4554-60.
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    June 2009
38. MORITA S , Okamoto I, Kobayashi K, Yamazaki K, et al
    Combined Survival Analysis of Prospective Clinical Trials of Gefitinib for Non-Small Cell Lung Cancer with EGFR Mutations.
    Clin Cancer Res. 2009.
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39. BRANNAN JM , Dong W, Prudkin L, Behrens C, et al
    Expression of the Receptor Tyrosine Kinase EphA2 Is Increased in Smokers and Predicts Poor Survival in Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2009.
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40. ANAGNOSTOU VK , Bepler G, Syrigos KN, Tanoue L, et al
    High expression of mammalian target of rapamycin is associated with better outcome for patients with early stage lung adenocarcinoma.
    Clin Cancer Res. 2009;15:4157-64.
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41. NAGANO T , Yasunaga M, Goto K, Kenmotsu H, et al
    Antitumor Activity of NK012 Combined with Cisplatin against Small Cell Lung Cancer and Intestinal Mucosal Changes in Tumor-Bearing Mouse after Treatment.
    Clin Cancer Res. 2009.
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42. PAPADAKI C , Mavroudis D, Trypaki M, Koutsopoulos A, et al
    Tumoral expression of TXR1 and TSP1 predicts overall survival of patients with lung adenocarcinoma treated with first-line docetaxel-gemcitabine regimen.
    Clin Cancer Res. 2009;15:3827-33.
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    May 2009
43. WU W , Zhang W, Qiao R, Chen D, et al
    Association of XPD Polymorphisms with Severe Toxicity in Non-Small Cell Lung Cancer Patients in a Chinese Population.
    Clin Cancer Res. 2009.
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44. HANRAHAN EO , Ryan AJ, Mann H, Kennedy SJ, et al
    Baseline vascular endothelial growth factor concentration as a potential predictive marker of benefit from vandetanib in non-small cell lung cancer.
    Clin Cancer Res. 2009;15:3600-9.
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45. HINGORANI P , Zhang W, Gorlick R, Kolb EA, et al
    Inhibition of Src phosphorylation alters metastatic potential of osteosarcoma in vitro but not in vivo.
    Clin Cancer Res. 2009;15:3416-22.
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46. SCHICHER N , Paulitschke V, Swoboda A, Kunstfeld R, et al
    Erlotinib and Bevacizumab Have Synergistic Activity against Melanoma.
    Clin Cancer Res. 2009;15:3495-502.
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47. CARRENO BM , Garbow JR, Kolar GR, Jackson EN, et al
    Immunodeficient mouse strains display marked variability in growth of human melanoma lung metastases.
    Clin Cancer Res. 2009;15:3277-86.
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48. RICKMAN OB , Vohra PK, Sanyal B, Vrana JA, et al
    Analysis of ErbB receptors in pulmonary carcinoid tumors.
    Clin Cancer Res. 2009;15:3315-24.
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49. NAUMOV GN , Nilsson MB, Cascone T, Briggs A, et al
    Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance.
    Clin Cancer Res. 2009;15:3484-94.
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50. HOMMA S , Ishii Y, Morishima Y, Yamadori T, et al
    Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer.
    Clin Cancer Res. 2009.
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51. YANAGISAWA S , Kadouchi I, Yokomori K, Hirose M, et al
    Identification and metastatic potential of tumor-initiating cells in malignant rhabdoid tumor of the kidney.
    Clin Cancer Res. 2009;15:3014-22.
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52. RUDOLPH D , Steegmaier M, Hoffmann M, Grauert M, et al
    BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity.
    Clin Cancer Res. 2009;15:3094-102.
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53. CHUNG EJ , Brown AP, Asano H, Mandler M, et al
    In vitro and in vivo radiosensitization with AZD6244 (ARRY-142886), an inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 kinase.
    Clin Cancer Res. 2009;15:3050-7.
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    April 2009
54. TAKEUCHI K , Choi YL, Togashi Y, Soda M, et al
    KIF5B-ALK, a Novel Fusion Oncokinase Identified by an Immunohistochemistry-based Diagnostic System for ALK-positive Lung Cancer.
    Clin Cancer Res. 2009.
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55. FENG LY , Ou ZL, Wu FY, Shen ZZ, et al
    Involvement of a Novel Chemokine Decoy Receptor CCX-CKR in Breast Cancer Growth, Metastasis and Patient Survival.
    Clin Cancer Res. 2009.
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56. SAKAMOTO KM , Frank DA
    CREB in the pathophysiology of cancer: implications for targeting transcription factors for cancer therapy.
    Clin Cancer Res. 2009;15:2583-7.
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57. IVANOVA AV , Goparaju CM, Ivanov SV, Nonaka D, et al
    Protumorigenic role of HAPLN1 and its IgV domain in malignant pleural mesothelioma.
    Clin Cancer Res. 2009;15:2602-11.
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58. ZHONG C , Qu X, Tan M, Meng YG, et al
    Characterization and regulation of bv8 in human blood cells.
    Clin Cancer Res. 2009;15:2675-84.
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59. YU J , Kane S, Wu J, Benedettini E, et al
    Mutation-Specific Antibodies for the Detection of EGFR Mutations in Non-Small-Cell Lung Cancer.
    Clin Cancer Res. 2009.
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60. YOU M , Wang D, Liu P, Vikis H, et al
    Fine Mapping of Chromosome 6q23-25 Region in Familial Lung Cancer Families Reveals RGS17 as a Likely Candidate Gene.
    Clin Cancer Res. 2009.
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61. KUANG Y , Rogers A, Yeap BY, Wang L, et al
    Noninvasive Detection of EGFR T790M in Gefitinib or Erlotinib Resistant Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2009.
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62. CHRISTIANI DC
    Lung Cancer Genetics: A Family Affair?
    Clin Cancer Res. 2009.
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63. KHATRI A , Husaini Y, Ow K, Chapman J, et al
    Cytosine deaminase-uracil phosphoribosyltransferase and interleukin (IL)-12 and IL-18: a multimodal anticancer interface marked by specific modulation in serum cytokines.
    Clin Cancer Res. 2009;15:2323-34.
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64. VIGANO A , Trutschnigg B, Kilgour RD, Hamel N, et al
    Relationship between angiotensin-converting enzyme gene polymorphism and body composition, functional performance, and blood biomarkers in advanced cancer patients.
    Clin Cancer Res. 2009;15:2442-7.
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    March 2009
65. LEE YJ , Cho A, Cho BC, Yun M, et al
    High Tumor Metabolic Activity as Measured by Fluorodeoxyglucose Positron Emission Tomography Is Associated with Poor Prognosis in Limited and Extensive Stage Small-Cell Lung Cancer.
    Clin Cancer Res. 2009.
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66. VAN KLAVEREN RJ , Van't Westeinde SC, de Hoop BJ, Hoogsteden HC, et al
    Stem Cells and the Natural History of Lung Cancer: Implications for Lung Cancer Screening.
    Clin Cancer Res. 2009.
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67. MUTTER R , Lu B, Carbone DP, Csiki I, et al
    A Phase II Study of Celecoxib in Combination with Paclitaxel, Carboplatin, and Radiotherapy for Patients with Inoperable Stage IIIA/B Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2009.
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68. YUNG TK , Chan KC, Mok TS, Tong J, et al
    Single-Molecule Detection of Epidermal Growth Factor Receptor Mutations in Plasma by Microfluidics Digital PCR in Non-Small Cell Lung Cancer Patients.
    Clin Cancer Res. 2009.
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69. PELED M , Shaish A, Katav A, Greenberger S, et al
    Systemic administration of a conditionally replicating adenovirus, targeted to angiogenesis, reduced lung metastases burden in cotton rats.
    Clin Cancer Res. 2009;15:1664-73.
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70. LINKOUS A , Geng L, Lyshchik A, Hallahan DE, et al
    Cytosolic phospholipase A2: targeting cancer through the tumor vasculature.
    Clin Cancer Res. 2009;15:1635-44.
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71. WU F , Zhu S, Ding Y, Beck WT, et al
    MicroRNA-mediated regulation of Ubc9 expression in cancer cells.
    Clin Cancer Res. 2009;15:1550-7.
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72. FALVELLA FS , Galvan A, Frullanti E, Spinola M, et al
    Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk.
    Clin Cancer Res. 2009;15:1837-42.
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73. DONG LF , Freeman R, Liu J, Zobalova R, et al
    Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II.
    Clin Cancer Res. 2009;15:1593-600.
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74. ERDOGAN E , Klee EW, Thompson EA, Fields AP, et al
    Meta-analysis of oncogenic protein kinase Ciota signaling in lung adenocarcinoma.
    Clin Cancer Res. 2009;15:1527-33.
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    February 2009
75. BOGOS K , Renyi-Vamos F, Dobos J, Kenessey I, et al
    High VEGFR-3-positive Circulating Lymphatic/Vascular Endothelial Progenitor Cell Level Is Associated with Poor Prognosis in Human Small Cell Lung Cancer.
    Clin Cancer Res. 2009.
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76. PARK JY , Lee WK, Jung DK, Choi JE, et al
    Polymorphisms in the FAS and FASL Genes and Survival of Early Stage Non-small Cell Lung Cancer.
    Clin Cancer Res. 2009.
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77. MARINOV M , Ziogas A, Pardo OE, Tan LT, et al
    AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001.
    Clin Cancer Res. 2009;15:1277-87.
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78. LIU X , Sempere LF, Galimberti F, Freemantle SJ, et al
    Uncovering growth-suppressive MicroRNAs in lung cancer.
    Clin Cancer Res. 2009;15:1177-83.
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79. BLEY CR , Jochum W, Orlowski K, Furmanova P, et al
    Role of the microenvironment for radiosensitization by patupilone.
    Clin Cancer Res. 2009;15:1335-42.
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80. WRAGE M , Ruosaari S, Eijk PP, Kaifi JT, et al
    Genomic Profiles Associated with Early Micrometastasis in Lung Cancer: Relevance of 4q Deletion.
    Clin Cancer Res. 2009.
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81. GRINBERG-RASHI H , Ofek E, Perelman M, Skarda J, et al
    The Expression of Three Genes in Primary Non-Small Cell Lung Cancer Is Associated with Metastatic Spread to the Brain.
    Clin Cancer Res. 2009.
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82. CEPPI P , Novello S, Cambieri A, Longo M, et al
    Polymerase {eta} mRNA Expression Predicts Survival of Non-Small Cell Lung Cancer Patients Treated with Platinum-Based Chemotherapy.
    Clin Cancer Res. 2009;15:1039-45.
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83. OKABE T , Okamoto I, Tsukioka S, Uchida J, et al
    Addition of S-1 to the Epidermal Growth Factor Receptor Inhibitor Gefitinib Overcomes Gefitinib Resistance in Non-small cell Lung Cancer Cell Lines with MET Amplification.
    Clin Cancer Res. 2009;15:907-913.
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84. AKHTAR S , Meeran SM, Katiyar N, Katiyar SK, et al
    Grape seed proanthocyanidins inhibit the growth of human non-small cell lung cancer xenografts by targeting insulin-like growth factor binding protein-3, tumor cell proliferation, and angiogenic factors.
    Clin Cancer Res. 2009;15:821-31.
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85. GEURTS TW , van Velthuysen ML, Broekman F, Hooft van Huysduynen T, et al
    Differential Diagnosis of Pulmonary Carcinoma Following Head and Neck Cancer by Genetic Analysis.
    Clin Cancer Res. 2009;15:980-985.
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    January 2009
86. BUDAK-ALPDOGAN T , Chen B, Warrier A, Medina DJ, et al
    Retinoblastoma Tumor Suppressor Gene Expression Determines the Response to Sequential Flavopiridol and Doxorubicin Treatment in Small-Cell Lung Carcinoma.
    Clin Cancer Res. 2009.
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87. ICHITE N , Chougule MB, Jackson T, Fulzele SV, et al
    Enhancement of docetaxel anticancer activity by a novel diindolylmethane compound in human non-small cell lung cancer.
    Clin Cancer Res. 2009;15:543-52.
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88. NYMARK P , Kettunen E, Aavikko M, Ruosaari S, et al
    Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer.
    Clin Cancer Res. 2009;15:468-75.
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89. PILONES KA , Kawashima N, Yang AM, Babb JS, et al
    Invariant natural killer T cells regulate breast cancer response to radiation and ctla-4 blockade.
    Clin Cancer Res. 2009;15:597-606.
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90. KANCHA RK , von Bubnoff N, Peschel C, Duyster J, et al
    Functional analysis of epidermal growth factor receptor (EGFR) mutations and potential implications for EGFR targeted therapy.
    Clin Cancer Res. 2009;15:460-7.
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91. DICKGREBER NJ , Fink TH, Latz JE, Hossain AM, et al
    Phase I and Pharmacokinetic Study of Pemetrexed plus Cisplatin in Chemonaive Patients with Locally Advanced or Metastatic Malignant Pleural Mesothelioma or Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2009;15:382-9.
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92. ROEPMAN P , Jassem J, Smit EF, Muley T, et al
    An immune response enriched 72-gene prognostic profile for early-stage non-small-cell lung cancer.
    Clin Cancer Res. 2009;15:284-90.
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