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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Lung Cancer

Free Subscription Articles published in Clin Cancer Res Retrieve available abstracts of 167 articles: HTML format

Single Articles

July 2008
1. KOIVUNEN JP , Mermel C, Zejnullahu K, Murphy C, et al
   EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer.
   Clin Cancer Res. 2008;14:4275-83.
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2. THAM LS , Wang L, Soo RA, Lee SC, et al
   A Pharmacodynamic Model for the Time Course of Tumor Shrinkage by Gemcitabine + Carboplatin in Non-Small Cell Lung Cancer Patients.
   Clin Cancer Res. 2008;14:4213-4218.
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3. OHE Y , Ichinose Y, Nakagawa K, Tamura T, et al
   Efficacy and safety of two doses of pemetrexed supplemented with folic Acid and vitamin B12 in previously treated patients with non-small cell lung cancer.
   Clin Cancer Res. 2008;14:4206-12.
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4. BELL DW , Brannigan BW, Matsuo K, Finkelstein DM, et al
   Increased Prevalence of EGFR-Mutant Lung Cancer in Women and in East Asian Populations: Analysis of Estrogen-Related Polymorphisms.
   Clin Cancer Res. 2008;14:4079-84.
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   June 2008
5. NIIKAWA H , Suzuki T, Miki Y, Suzuki S, et al
   Intratumoral Estrogens and Estrogen Receptors in Human Non-Small Cell Lung Carcinoma.
   Clin Cancer Res. 2008;.
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6. FELIP E , Rojo F, Reck M, Heller A, et al
   A Phase II Pharmacodynamic Study of Erlotinib in Patients with Advanced Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy.
   Clin Cancer Res. 2008;14:3867-74.
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7. AHN MJ , Park BB, Ahn JS, Kim SW, et al
   Are there any ethnic differences in molecular predictors of erlotinib efficacy in advanced non-small cell lung cancer?
   Clin Cancer Res. 2008;14:3860-6.
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8. JOHN T , Caballero OL, Svobodova SJ, Kong A, et al
   ECSA/DPPA2 is an Embryo-Cancer Antigen that Is Coexpressed with Cancer-Testis Antigens in Non-Small Cell Lung Cancer.
   Clin Cancer Res. 2008;14:3291-8.
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9. SHOEMAKER AR , Mitten MJ, Adickes J, Ackler S, et al
   Activity of the Bcl-2 Family Inhibitor ABT-263 in a Panel of Small Cell Lung Cancer Xenograft Models.
   Clin Cancer Res. 2008;14:3268-77.
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   May 2008
10. KIM SO , Jeong JY, Kim MR, Cho HJ, et al
    Efficacy of gemcitabine in patients with non-small cell lung cancer according to promoter polymorphisms of the ribonucleotide reductase m1 gene.
    Clin Cancer Res. 2008;14:3083-8.
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11. ENGELMAN JA , Janne PA
    Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer.
    Clin Cancer Res. 2008;14:2895-9.
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12. HU Z , Liu H, Wang H, Miao R, et al
    Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility.
    Clin Cancer Res. 2008;14:2887-91.
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13. YU D , Zhang X, Liu J, Yuan P, et al
    Characterization of functional excision repair cross-complementation group 1 variants and their association with lung cancer risk and prognosis.
    Clin Cancer Res. 2008;14:2878-86.
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    April 2008
14. BACH P
    Computed tomography screening for lung cancer.
    Clin Cancer Res. 2008;14:2511.
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15. SILVESTRI GA
    Deaths among Patients with Screen-Detected Lung Cancer.
    Clin Cancer Res. 2008;14:2511.
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16. KATO T , Sato N, Takano A, Miyamoto M, et al
    Activation of Placenta-Specific Transcription Factor Distal-less Homeobox 5 Predicts Clinical Outcome in Primary Lung Cancer Patients.
    Clin Cancer Res. 2008;14:2363-70.
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17. KIM JH , Bogner PN, Baek SH, Ramnath N, et al
    Up-regulation of peroxiredoxin 1 in lung cancer and its implication as a prognostic and therapeutic target.
    Clin Cancer Res. 2008;14:2326-33.
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18. KAMALIAN L , Gosney JR, Forootan SS, Foster CS, et al
    Increased expression of id family proteins in small cell lung cancer and its prognostic significance.
    Clin Cancer Res. 2008;14:2318-25.
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19. ORITA H , Coulter J, Tully E, Kuhajda FP, et al
    Inhibiting fatty acid synthase for chemoprevention of chemically induced lung tumors.
    Clin Cancer Res. 2008;14:2458-64.
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20. FIDLER MJ , Argiris A, Patel JD, Johnson DH, et al
    The potential predictive value of cyclooxygenase-2 expression and increased risk of gastrointestinal hemorrhage in advanced non-small cell lung cancer patients treated with erlotinib and celecoxib.
    Clin Cancer Res. 2008;14:2088-94.
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21. NA II , Byun BH, Kang HJ, Cheon GJ, et al
    18F-Fluoro-2-Deoxy-Glucose Uptake Predicts Clinical Outcome in Patients with Gefitinib-Treated Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2008;14:2036-41.
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22. LAM S , Standish B, Baldwin C, McWilliams A, et al
    In vivo optical coherence tomography imaging of preinvasive bronchial lesions.
    Clin Cancer Res. 2008;14:2006-11.
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    March 2008
23. TAN YH , Lee KH, Lin T, Sun YC, et al
    Cytotoxicity and Proteomics Analyses of OSU03013 in Lung Cancer.
    Clin Cancer Res. 2008;14:1823-1830.
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24. TIBALDI C , Giovannetti E, Vasile E, Mey V, et al
    Correlation of CDA, ERCC1, and XPD Polymorphisms with Response and Survival in Gemcitabine/Cisplatin-Treated Advanced Non-Small Cell Lung Cancer Patients.
    Clin Cancer Res. 2008;14:1797-803.
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25. YOON D , Agarwal N, Prchal JT
    Does erythropoietin promote tumor growth?
    Clin Cancer Res. 2008;14:1920.
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26. BARYSHNIKOVA E , Destro A, Infante MV, Cavuto S, et al
    Molecular alterations in spontaneous sputum of cancer-free heavy smokers: results from a large screening program.
    Clin Cancer Res. 2008;14:1913-9.
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27. CRESCENZI E , Palumbo G, de Boer J, Brady HJ, et al
    Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy.
    Clin Cancer Res. 2008;14:1877-87.
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28. CHOY H , Park C, Yao M
    Current status and future prospects for satraplatin, an oral platinum analogue.
    Clin Cancer Res. 2008;14:1633-8.
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29. BENNOUNA J , Delord JP, Campone M, Nguyen L, et al
    Vinflunine: a new microtubule inhibitor agent.
    Clin Cancer Res. 2008;14:1625-32.
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30. CHEN J , Lam S, Pilon A, McWilliams A, et al
    Higher Levels of the Anti-inflammatory Protein CC10 Are Associated with Improvement in Bronchial Dysplasia and Sputum Cytometric Assessment in Individuals at High Risk for Lung Cancer.
    Clin Cancer Res. 2008;14:1590-7.
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31. CHIAPPORI AA , Haura E, Rodriguez FA, Boulware D, et al
    Phase I/II Study of Atrasentan, an Endothelin A Receptor Antagonist, in Combination with Paclitaxel and Carboplatin as First-Line Therapy in Advanced Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2008;14:1464-9.
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32. DOWLATI A , Gray R, Sandler AB, Schiller JH, et al
    Cell Adhesion Molecules, Vascular Endothelial Growth Factor, and Basic Fibroblast Growth Factor in Patients with Non-Small Cell Lung Cancer Treated with Chemotherapy with or without Bevacizumab--an Eastern Cooperative Oncology Group Study.
    Clin Cancer Res. 2008;14:1407-12.
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33. PLANQUE C , Li L, Zheng Y, Soosaipillai A, et al
    A multiparametric serum kallikrein panel for diagnosis of non-small cell lung carcinoma.
    Clin Cancer Res. 2008;14:1355-62.
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34. OH SH , Jin Q, Kim ES, Khuri FR, et al
    Insulin-like growth factor-I receptor signaling pathway induces resistance to the apoptotic activities of SCH66336 (lonafarnib) through Akt/mammalian target of rapamycin-mediated increases in survivin expression.
    Clin Cancer Res. 2008;14:1581-9.
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35. LOU Y , Basha G, Seipp RP, Cai B, et al
    Combining the antigen processing components TAP and Tapasin elicits enhanced tumor-free survival.
    Clin Cancer Res. 2008;14:1494-501.
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36. ZIMMERER JM , Lehman AM, Ruppert AS, Noble CW, et al
    IFN-alpha-2b-induced signal transduction and gene regulation in patient peripheral blood mononuclear cells is not enhanced by a dose increase from 5 to 10 megaunits/m2.
    Clin Cancer Res. 2008;14:1438-45.
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37. SHIOMI K , Hagiwara Y, Sonoue K, Segawa T, et al
    Sensitive and specific new enzyme-linked immunosorbent assay for N-ERC/mesothelin increases its potential as a useful serum tumor marker for mesothelioma.
    Clin Cancer Res. 2008;14:1431-7.
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38. GARBOW JR , Wang M, Wang Y, Lubet RA, et al
    Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging.
    Clin Cancer Res. 2008;14:1363-7.
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39. GIUSTI RM , Shastri K, Pilaro AM, Fuchs C, et al
    U.S. Food and Drug Administration approval: panitumumab for epidermal growth factor receptor-expressing metastatic colorectal carcinoma with progression following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing chemotherapy regimens.
    Clin Cancer Res. 2008;14:1296-302.
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    February 2008
40. TANAKA T , Munshi A, Brooks C, Liu J, et al
    Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity.
    Clin Cancer Res. 2008;14:1266-73.
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41. CEPPI P , Volante M, Ferrero A, Righi L, et al
    Thymidylate synthase expression in gastroenteropancreatic and pulmonary neuroendocrine tumors.
    Clin Cancer Res. 2008;14:1059-64.
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42. GARCIA B , Neninger E, de la Torre A, Leonard I, et al
    Effective inhibition of the epidermal growth factor/epidermal growth factor receptor binding by anti-epidermal growth factor antibodies is related to better survival in advanced non-small-cell lung cancer patients treated with the epidermal growth factor
    Clin Cancer Res. 2008;14:840-6.
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43. OGINO H , Yano S, Kakiuchi S, Muguruma H, et al
    Follistatin Suppresses the Production of Experimental Multiple-Organ Metastasis by Small Cell Lung Cancer Cells in Natural Killer Cell-Depleted SCID Mice.
    Clin Cancer Res. 2008;14:660-7.
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44. CAI KX , Tse LY, Leung C, Tam PK, et al
    Suppression of lung tumor growth and metastasis in mice by adeno-associated virus-mediated expression of vasostatin.
    Clin Cancer Res. 2008;14:939-49.
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45. EZUMI K , Yamamoto H, Murata K, Higashiyama M, et al
    Aberrant Expression of Connexin 26 Is Associated with Lung Metastasis of Colorectal Cancer.
    Clin Cancer Res. 2008;14:677-684.
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46. TALMADGE JE
    Follistatin as an inhibitor of experimental metastasis.
    Clin Cancer Res. 2008;14:624-6.
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    January 2008
47. ZHAI R , Liu G, Zhou W, Su L, et al
    Vascular endothelial growth factor genotypes, haplotypes, gender, and the risk of non-small cell lung cancer.
    Clin Cancer Res. 2008;14:612-7.
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48. SCHRUMP DS , Fischette MR, Nguyen DM, Zhao M, et al
    Clinical and molecular responses in lung cancer patients receiving romidepsin.
    Clin Cancer Res. 2008;14:188-98.
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49. PRUDKIN L , Behrens C, Liu DD, Zhou X, et al
    Loss and Reduction of Fus1 Protein Expression is a Frequent Phenomenon in the Pathogenesis of Lung Cancer.
    Clin Cancer Res. 2008;14:41-47.
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50. GOW CH , Chien CR, Chang YL, Chiu YH, et al
    Radiotherapy in lung adenocarcinoma with brain metastases: effects of activating epidermal growth factor receptor mutations on clinical response.
    Clin Cancer Res. 2008;14:162-8.
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    December 2007
51. HUANG CL , Liu D, Nakano J, Yokomise H, et al
    E2F1 Overexpression Correlates with Thymidylate Synthase and Survivin Gene Expressions and Tumor Proliferation in Non Small-Cell Lung Cancer.
    Clin Cancer Res. 2007;13:6938-46.
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52. ORITA H , Coulter J, Lemmon C, Tully E, et al
    Selective inhibition of Fatty Acid synthase for lung cancer treatment.
    Clin Cancer Res. 2007;13:7139-45.
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    November 2007
53. DONNEM T , Al-Saad S, Al-Shibli K, Delghandi MP, et al
    Inverse Prognostic Impact of Angiogenic Marker Expression in Tumor Cells versus Stromal Cells in Non Small Cell Lung Cancer.
    Clin Cancer Res. 2007;13:6649-6657.
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54. TANIWAKI M , Takano A, Ishikawa N, Yasui W, et al
    Activation of KIF4A as a Prognostic Biomarker and Therapeutic Target for Lung Cancer.
    Clin Cancer Res. 2007;13:6624-6631.
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55. LOPREVITE M , Tiseo M, Chiaramondia M, Capelletti M, et al
    Buccal Mucosa Cells as In vivo Model to Evaluate Gefitinib Activity in Patients with Advanced Non Small Cell Lung Cancer.
    Clin Cancer Res. 2007;13:6518-6526.
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56. KAIRA K , Oriuchi N, Otani Y, Shimizu K, et al
    Fluorine-18-{alpha}-Methyltyrosine Positron Emission Tomography for Diagnosis and Staging of Lung Cancer: A Clinicopathologic Study.
    Clin Cancer Res. 2007;13:6369-6378.
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    October 2007
57. LEE DH , Kim SW, Bae KS, Hong JS, et al
    A phase I and pharmacologic study of belotecan in combination with Cisplatin in patients with previously untreated extensive-stage disease small cell lung cancer.
    Clin Cancer Res. 2007;13:6182-6.
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58. HERBST RS , Davies AM, Natale RB, Dang TP, et al
    Efficacy and safety of single-agent pertuzumab, a human epidermal receptor dimerization inhibitor, in patients with non small cell lung cancer.
    Clin Cancer Res. 2007;13:6175-81.
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59. SUZUKI M , Shigematsu H, Nakajima T, Kubo R, et al
    Synchronous Alterations of Wnt and Epidermal Growth Factor Receptor Signaling Pathways through Aberrant Methylation and Mutation in Non Small Cell Lung Cancer.
    Clin Cancer Res. 2007;13:6087-92.
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60. LIBY K , Royce DB, Risingsong R, Williams CR, et al
    A new rexinoid, NRX194204, prevents carcinogenesis in both the lung and mammary gland.
    Clin Cancer Res. 2007;13:6237-43.
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61. WANG W , Spitz MR, Yang H, Lu C, et al
    Genetic variants in cell cycle control pathway confer susceptibility to lung cancer.
    Clin Cancer Res. 2007;13:5974-81.
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62. TOYOOKA S , Matsuo K, Shigematsu H, Kosaka T, et al
    The Impact of Sex and Smoking Status on the Mutational Spectrum of Epidermal Growth Factor Receptor Gene in Non small Cell Lung Cancer.
    Clin Cancer Res. 2007;13:5763-5768.
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    September 2007
63. ZHONG H , Han B, Tourkova IL, Lokshin A, et al
    Low-dose Paclitaxel prior to intratumoral dendritic cell vaccine modulates intratumoral cytokine network and lung cancer growth.
    Clin Cancer Res. 2007;13:5455-62.
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64. TAKANO T , Ohe Y, Tsuta K, Fukui T, et al
    Epidermal growth factor receptor mutation detection using high-resolution melting analysis predicts outcomes in patients with advanced non small cell lung cancer treated with gefitinib.
    Clin Cancer Res. 2007;13:5385-90.
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65. CRISTAUDO A , Foddis R, Vivaldi A, Guglielmi G, et al
    Clinical significance of serum mesothelin in patients with mesothelioma and lung cancer.
    Clin Cancer Res. 2007;13:5076-81.
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66. HOSHI K , Takakura H, Mitani Y, Tatsumi K, et al
    Rapid Detection of Epidermal Growth Factor Receptor Mutations in Lung Cancer by the SMart-Amplification Process.
    Clin Cancer Res. 2007;13:4974-83.
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67. PAO W , Ladanyi M
    Epidermal Growth Factor Receptor Mutation Testing in Lung Cancer: Searching for the Ideal Method.
    Clin Cancer Res. 2007;13:4954-4955.
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68. AISNER J
    CT Screening for Lung Cancer: Are We Ready for Wide-Scale Application?
    Clin Cancer Res. 2007;13:4951-3.
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69. HENSCHKE CI
    Survival of patients with clinical stage I lung cancer diagnosed by computed tomography screening for lung cancer.
    Clin Cancer Res. 2007;13:4949-50.
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70. HE J , Luster TA, Thorpe PE
    Radiation-enhanced vascular targeting of human lung cancers in mice with a monoclonal antibody that binds anionic phospholipids.
    Clin Cancer Res. 2007;13:5211-8.
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71. RIELY GJ , Kris MG, Zhao B, Akhurst T, et al
    Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus.
    Clin Cancer Res. 2007;13:5150-5.
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    August 2007
72. ZOU Y , Tornos C, Qiu X, Lia M, et al
    p53 Aerosol Formulation with Low Toxicity and High Efficiency for Early Lung Cancer Treatment.
    Clin Cancer Res. 2007;13:4900-8.
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73. SAINTIGNY P , Besse B, Callard P, Vergnaud AC, et al
    Erythropoietin and erythropoietin receptor coexpression is associated with poor survival in stage I non small cell lung cancer.
    Clin Cancer Res. 2007;13:4825-31.
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74. HONG TM , Chen YL, Wu YY, Yuan A, et al
    Targeting Neuropilin 1 as an Antitumor Strategy in Lung Cancer.
    Clin Cancer Res. 2007;13:4759-4768.
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75. ZHANG Q , Tang X, Zhang ZF, Velikina R, et al
    Nicotine Induces Hypoxia-Inducible Factor-1{alpha} Expression in Human Lung Cancer Cells via Nicotinic Acetylcholine Receptor Mediated Signaling Pathways.
    Clin Cancer Res. 2007;13:4686-94.
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76. SANGHA R , Butts C
    L-BLP25: A Peptide Vaccine Strategy in Non Small Cell Lung Cancer.
    Clin Cancer Res. 2007;13:4652s-4s.
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77. DAVIES AM , Lara PN Jr, Mack PC, Gandara DR, et al
    Incorporating bortezomib into the treatment of lung cancer.
    Clin Cancer Res. 2007;13:4647s-51s.
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78. HERBST RS , Oh Y, Wagle A, Lahn M, et al
    Enzastaurin, a Protein Kinase C{beta} Selective Inhibitor, and Its Potential Application as an Anticancer Agent in Lung Cancer.
    Clin Cancer Res. 2007;13:4641s-6s.
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79. ENGELMAN JA
    The role of phosphoinositide 3-kinase pathway inhibitors in the treatment of lung cancer.
    Clin Cancer Res. 2007;13:4637s-40s.
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80. BAUMAN JE , Eaton KD, Martins RG
    Antagonism of platelet-derived growth factor receptor in non small cell lung cancer: rationale and investigations.
    Clin Cancer Res. 2007;13:4632s-6s.
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81. JOHNSON BE , Jackman D, Janne PA
    Rationale for a Phase I Trial of Erlotinib and the Mammalian Target of Rapamycin Inhibitor Everolimus (RAD001) for Patients with Relapsed Non Small Cell Lung Cancer.
    Clin Cancer Res. 2007;13:4628s-31s.
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82. RIELY GJ , Miller VA
    Vascular endothelial growth factor trap in non small cell lung cancer.
    Clin Cancer Res. 2007;13:4623s-7s.
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83. HANRAHAN EO , Heymach JV
    Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitors Vandetanib (ZD6474) and AZD2171 in Lung Cancer.
    Clin Cancer Res. 2007;13:4617s-22s.
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84. SANDLER A
    Bevacizumab in non small cell lung cancer.
    Clin Cancer Res. 2007;13:4613s-6s.
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85. MORGENSZTERN D , Govindan R
    Is there a role for cetuximab in non small cell lung cancer?
    Clin Cancer Res. 2007;13:4602s-5s.
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86. SOCINSKI MA
    Antibodies to the epidermal growth factor receptor in non small cell lung cancer: current status of matuzumab and panitumumab.
    Clin Cancer Res. 2007;13:4597s-601s.
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87. WONG KK
    HKI-272 in Non Small Cell Lung Cancer.
    Clin Cancer Res. 2007;13:4593s-6s.
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88. PEREZ-SOLER R
    Erlotinib: recent clinical results and ongoing studies in non small cell lung cancer.
    Clin Cancer Res. 2007;13:4589s-92s.
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89. LYNCH TJ , Bonomi PD, Butts C, Davies AM, et al
    Novel agents in the treatment of lung cancer: fourth cambridge conference.
    Clin Cancer Res. 2007;13:4583s-8s.
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90. YUE W , Dacic S, Sun Q, Landreneau R, et al
    Frequent Inactivation of RAMP2, EFEMP1 and Dutt1 in Lung Cancer by Promoter Hypermethylation.
    Clin Cancer Res. 2007;13:4336-44.
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91. 
    Proceedings of the 4th Cambridge Conference on Novel Agents in the Treatment of Lung Cancer, September 29-30, 2006, Cambridge, Massachusetts, USA.
    Clin Cancer Res. 2007;13.
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92. BONOMI PD , Buckingham L, Coon J
    Selecting patients for treatment with epidermal growth factor tyrosine kinase inhibitors.
    Clin Cancer Res. 2007;13.
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93. GORDON N , Koshkina NV, Jia SF, Khanna C, et al
    Corruption of the Fas pathway delays the pulmonary clearance of murine osteosarcoma cells, enhances their metastatic potential, and reduces the effect of aerosol gemcitabine.
    Clin Cancer Res. 2007;13.
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    July 2007
94. INAMOTO T , Yamada T, Ohnuma K, Kina S, et al
    Humanized anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors.
    Clin Cancer Res. 2007;13:4191-200.
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95. FILIPITS M , Haddad V, Schmid K, Huynh A, et al
    Multidrug resistance proteins do not predict benefit of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: international adjuvant lung cancer trial biologic program.
    Clin Cancer Res. 2007;13:3892-8.
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96. KIM JH , Bogner PN, Ramnath N, Park Y, et al
    Elevated Peroxiredoxin 1, but not NF-E2-Related Factor 2, Is an Independent Prognostic Factor for Disease Recurrence and Reduced Survival in Stage I Non-Small Cell Lung Cancer.
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