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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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Articles published in Cancer Chemother Pharmacol

Retrieve available abstracts of 45 articles:
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Single Articles


    May 2008
  1. LEGGAS M , Kuo KL, Robert F, Cloud G, et al
    Intensive anti-inflammatory therapy with dexamethasone in patients with non-small cell lung cancer: effect on chemotherapy toxicity and efficacy.
    Cancer Chemother Pharmacol. 2008;.
    PubMed     Related articles    Abstract available


    April 2008
  2. FELIU J , Firvida JL, Castro J, Madronal C, et al
    Combination therapy with docetaxel and low dose of cisplatin in elderly patients with advanced non-small cell lung cancer: multicenter phase II study.
    Cancer Chemother Pharmacol. 2008;.
    PubMed     Related articles    Abstract available


    March 2008
  3. JACKSON T , Chougule MB, Ichite N, Patlolla RR, et al
    Antitumor activity of noscapine in human non-small cell lung cancer xenograft model.
    Cancer Chemother Pharmacol. 2008;.
    PubMed     Related articles    Abstract available


  4. YAMAMOTO N , Horiike A, Fujisaka Y, Murakami H, et al
    Phase I dose-finding and pharmacokinetic study of the oral epidermal growth factor receptor tyrosine kinase inhibitor Ro50-8231 (erlotinib) in Japanese patients with solid tumors.
    Cancer Chemother Pharmacol. 2008;61:489-96.
    PubMed     Related articles    Abstract available


    February 2008
  5. CHOI B , Robins HI, Schiller J, Mehta M, et al
    A phase I study of gemcitabine plus palliative radiation therapy for advanced lung cancer.
    Cancer Chemother Pharmacol. 2008;.
    PubMed     Related articles    Abstract available


  6. HACKER A , Marton LJ, Sobolewski M, Casero RA Jr, et al
    In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells.
    Cancer Chemother Pharmacol. 2008;.
    PubMed     Related articles    Abstract available


  7. PARK SH , Cho EK, Kim Y, Kyung SY, et al
    Salvage treatment with topotecan in patients with irinotecan-refractory small cell lung cancer.
    Cancer Chemother Pharmacol. 2008;.
    PubMed     Related articles    Abstract available


    January 2008
  8. HORTI J , Juhasz E, Monostori Z, Maeda K, et al
    Phase I study of TZT-1027, a novel synthetic dolastatin 10 derivative, for the treatment of patients with non-small cell lung cancer.
    Cancer Chemother Pharmacol. 2008;.
    PubMed     Related articles    Abstract available


  9. HSU TS , Chen C, Lee PT, Chiu SJ, et al
    7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway.
    Cancer Chemother Pharmacol. 2008;.
    PubMed     Related articles    Abstract available


  10. FINE RL , Fogelman DR, Schreibman SM, Desai M, et al
    The gemcitabine, docetaxel, and capecitabine (GTX) regimen for metastatic pancreatic cancer: a retrospective analysis.
    Cancer Chemother Pharmacol. 2008;61:167-75.
    PubMed     Related articles    Abstract available


    December 2007
  11. LEE I , Shogen K
    Mechanisms of enhanced tumoricidal efficacy of multiple small dosages of ranpirnase, the novel cytotoxic ribonuclease, on lung cancer.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


    November 2007
  12. SAIF MW , Sellers S, Li M, Wang W, et al
    A phase I study of bi-weekly administration of 24-h gemcitabine followed by 24-h irinotecan in patients with solid tumors.
    Cancer Chemother Pharmacol. 2007;60:871-82.
    PubMed     Related articles    Abstract available


  13. OKU H , Wongtangtintharn S, Iwasaki H, Inafuku M, et al
    Tumor specific cytotoxicity of glucosylceramide.
    Cancer Chemother Pharmacol. 2007;60:767-75.
    PubMed     Related articles    Abstract available


    October 2007
  14. OSHITA F , Yamada K, Saito H, Noda K, et al
    Phase II study of nedaplatin and irinotecan followed by gefitinib for elderly patients with unresectable non-small cell lung cancer.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  15. STINCHCOMBE TE , Socinski MA, Walko CM, O'Neil BH, et al
    Phase I and pharmacokinetic trial of carboplatin and albumin-bound paclitaxel, ABI-007 (Abraxane) on three treatment schedules in patients with solid tumors.
    Cancer Chemother Pharmacol. 2007;60:759-66.
    PubMed     Related articles    Abstract available


  16. SHIBATA MA , Akao Y, Shibata E, Nozawa Y, et al
    Vaticanol C, a novel resveratrol tetramer, reduces lymph node and lung metastases of mouse mammary carcinoma carrying p53 mutation.
    Cancer Chemother Pharmacol. 2007;60:681-91.
    PubMed     Related articles    Abstract available


    August 2007
  17. TOMONAGA N , Nakamura Y, Soda H, Nagashima S, et al
    Phase I study of vinorelbine and irinotecan in previously untreated patients with advanced non-small cell lung cancer.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  18. SATO H , Fukumoto K, Hada S, Hagiwara H, et al
    Enhancing effect of connexin 32 gene on vinorelbine-induced cytotoxicity in A549 lung adenocarcinoma cells.
    Cancer Chemother Pharmacol. 2007;60:449-57.
    PubMed     Related articles    Abstract available


  19. IZZEDINE H , Buhaescu I, Rixe O, Deray G, et al
    Sunitinib malate.
    Cancer Chemother Pharmacol. 2007;60:357-64.
    PubMed     Related articles    Abstract available


    July 2007
  20. PIANTEDOSI FV , Caputo F, Mazzarella G, Gilli M, et al
    Gemcitabine, ifosfamide and paclitaxel in advanced/metastatic non-small cell lung cancer patients: a phase II study.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  21. MU D , Zhang W, Chu D, Liu T, et al
    The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


    June 2007
  22. OKUDA K , Hirose T, Ishida H, Kusumoto S, et al
    Phase I study of the combination of nedaplatin and weekly paclitaxel in patients with advanced non-small cell lung cancer.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  23. CHOI HJ , Cho BC, Shin SJ, Cheon SH, et al
    Combination of topotecan and etoposide as a salvage treatment for patients with recurrent small cell lung cancer following irinotecan and platinum first-line chemotherapy.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  24. TAS F , Duranyildiz D, Soydinc HO, Cicin I, et al
    Effect of maximum-tolerated doses and low-dose metronomic chemotherapy on serum vascular endothelial growth factor and thrombospondin-1 levels in patients with advanced nonsmall cell lung cancer.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  25. WANG LR , Huang MZ, Zhang GB, Xu N, et al
    Phase II study of gemcitabine and carboplatin in patients with advanced non-small-cell lung cancer.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  26. ZASTRE J , Anantha M, Ramsay E, Bally M, et al
    Irinotecan-cisplatin interactions assessed in cell-based screening assays: cytotoxicity, drug accumulation and DNA adduct formation in an NSCLC cell line.
    Cancer Chemother Pharmacol. 2007;60:91-102.
    PubMed     Related articles    Abstract available


    May 2007
  27. LI J , Viallet J, Haura EB
    A small molecule pan-Bcl-2 family inhibitor, GX15-070, induces apoptosis and enhances cisplatin-induced apoptosis in non-small cell lung cancer cells.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  28. OHYANAGI F , Horiike A, Okano Y, Satoh Y, et al
    Phase II trial of gemcitabine and irinotecan in previously treated patients with small-cell lung cancer.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  29. JORGENSEN TJ , Tian H, Joseph IB, Menon K, et al
    Chemosensitization and radiosensitization of human lung and colon cancers by antimitotic agent, ABT-751, in athymic murine xenograft models of subcutaneous tumor growth.
    Cancer Chemother Pharmacol. 2007;59:725-32.
    PubMed     Related articles    Abstract available


    March 2007
  30. TABATA M , Kiura K, Okimoto N, Segawa Y, et al
    A phase II trial of cisplatin and irinotecan alternating with doxorubicin, cyclophosphamide and etoposide in previously untreated patients with extensive-disease small-cell lung cancer.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  31. FINE RL , Shah SS, Moulton TA, Yu IR, et al
    Androgen and c-Kit receptors in desmoplastic small round cell tumors resistant to chemotherapy: novel targets for therapy.
    Cancer Chemother Pharmacol. 2007;59:429-37.
    PubMed     Related articles    Abstract available


    February 2007
  32. HIROSE T , Shirai T, Ishida H, Ando K, et al
    Phase II study of biweekly administration of docetaxel and irinotecan in patients with refractory or relapsed advanced non-small cell lung cancer.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


  33. CASAL J , Amenedo M, Mel JR, Anton LM, et al
    Gemcitabine plus docetaxel as first-line chemotherapy in patients with advanced non-small cell lung cancer: a lung cancer Galician group phase II study.
    Cancer Chemother Pharmacol. 2007;.
    PubMed     Related articles    Abstract available


    January 2007
  34. MOREB JS , Mohuczy D, Ostmark B, Zucali JR, et al
    RNAi-mediated knockdown of aldehyde dehydrogenase class-1A1 and class-3A1 is specific and reveals that each contributes equally to the resistance against 4-hydroperoxycyclophosphamide.
    Cancer Chemother Pharmacol. 2007;59:127-36.
    PubMed     Related articles    Abstract available


    December 2006
  35. KAWAMURA M , Eguchi K, Izumi Y, Yamato Y, et al
    Phase II trial of gemcitabine and docetaxel in patients with completely resected stage IIA-IIIA non-small-cell lung cancer.
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


    November 2006
  36. WANG L , Wu X, Huang M, Cai J, et al
    The efficacy and relationship between peak concentration and toxicity profile of fixed-dose-rate gemcitabine plus carboplatin in patients with advanced non-small-cell lung cancer.
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


  37. MORI K , Kamiyama Y, Kondo T, Kano Y, et al
    Phase II study of weekly chemotherapy with paclitaxel and gemcitabine as second-line treatment for advanced non-small cell lung cancer after treatment with platinum-based chemotherapy.
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


  38. JOHNSON BE , Jackman D, Janne PA
    Impact of EGFR mutations on treatment of non-small cell lung cancer.
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


  39. PAO W
    Defining clinically relevant molecular subsets of lung cancer.
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


  40. YATABE Y
    Molecular classification of tumors with special reference to EGFR mutation in lung cancer.
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


  41. TOYOOKA S , Soh J, Shigematsu H, Aoe M, et al
    The impact and role of EGFR gene mutation on non-small cell lung cancer.
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


  42. ICHINOSE Y
    A randomized phase III trial of adjuvant treatment for resected non-small cell lung cancer in Japan.
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


    October 2006
  43. COHEN RB , Langer CJ, Simon GR, Eisenberg PD, et al
    A phase I/randomized phase II, non-comparative, multicenter, open label trial of CP-547,632 in combination with paclitaxel and carboplatin or paclitaxel and carboplatin alone as first-line treatment for advanced non-small cell lung cancer (NSCLC).
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


  44. BINDER D , Schweisfurth H, Grah C, Schaper C, et al
    Docetaxel/gemcitabine or cisplatin/gemcitabine followed by docetaxel in the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC): results of a multicentre randomized phase II trial.
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


    September 2006
  45. TABATA M , Kozuki T, Ueoka H, Kiura K, et al
    A triplet chemotherapy with cisplatin, docetaxel and gemcitabine in patients with advanced non-small-cell lung cancer: a phase I/II study.
    Cancer Chemother Pharmacol. 2006;.
    PubMed     Related articles    Abstract available


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