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The Medical Article of the Year 2008


  Liver Diseases

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Articles published in Gastroenterology

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Single Articles


    June 2008
  1. TALWALKAR JA
    Elastography for Detecting Hepatic Fibrosis: Options and Considerations.
    Gastroenterology. 2008;.
    PubMed     Related articles   


  2. SPRENGERS D , Sille FC, Derkow K, Besra GS, et al
    Critical role for CD1d-restricted invariant NKT cells in stimulating intrahepatic CD8 T-cell responses to liver antigen.
    Gastroenterology. 2008;134:2132-43.
    PubMed     Related articles    Abstract available


  3. ISHIZAWA T , Hasegawa K, Aoki T, Takahashi M, et al
    Neither multiple tumors nor portal hypertension are surgical contraindications for hepatocellular carcinoma.
    Gastroenterology. 2008;134:1908-16.
    PubMed     Related articles    Abstract available


    May 2008
  4. CALLSTROM MR , Charboneau JW
    Technologies for Ablation of Hepatocellular Carcinoma.
    Gastroenterology. 2008;.
    PubMed     Related articles   


  5. RADZIEWICZ H , Hanson HL, Ahmed R, Grakoui A, et al
    Unraveling the Role of PD-1/PD-L Interactions in Persistent Hepatotropic Infections: Potential for Therapeutic Application?
    Gastroenterology. 2008;.
    PubMed     Related articles   


  6. ZHAO J , Dong L, Lu B, Wu G, et al
    Down-Regulation of Osteopontin Suppresses Growth and Metastasis of Hepatocellular Carcinoma Via Induction of Apoptosis.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  7. EL-SERAG HB , Marrero JA, Rudolph L, Reddy KR, et al
    Diagnosis and treatment of hepatocellular carcinoma.
    Gastroenterology. 2008;134:1752-63.
    PubMed     Related articles    Abstract available


  8. SANYAL AJ , Bosch J, Blei A, Arroyo V, et al
    Portal hypertension and its complications.
    Gastroenterology. 2008;134:1715-28.
    PubMed     Related articles   


  9. TORRES DM , Harrison SA
    Diagnosis and therapy of nonalcoholic steatohepatitis.
    Gastroenterology. 2008;134:1682-98.
    PubMed     Related articles    Abstract available


  10. FRIEDMAN SL
    Mechanisms of hepatic fibrogenesis.
    Gastroenterology. 2008;134:1655-69.
    PubMed     Related articles    Abstract available


  11. VILLANUEVA C , Aracil C, Colomo A, Balanzo J, et al
    Nonselective beta-blockers and hepatic venous pressure gradient monitoring: what lies behind nonresponse.
    Gastroenterology. 2008;134:1626-7.
    PubMed     Related articles   


  12. VOLK M , Marrero JA
    Liver transplantation for hepatocellular carcinoma: who benefits and who is harmed?
    Gastroenterology. 2008;134:1612-4.
    PubMed     Related articles   


  13. LIM JK , Groszmann RJ
    Vasoconstrictor therapy for the hepatorenal syndrome.
    Gastroenterology. 2008;134:1608-11.
    PubMed     Related articles   


  14. YEA S , Narla G, Zhao X, Garg R, et al
    Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma.
    Gastroenterology. 2008;134:1521-31.
    PubMed     Related articles    Abstract available


  15. REINEHR R , Sommerfeld A, Haussinger D
    CD95 ligand is a proliferative and antiapoptotic signal in quiescent hepatic stellate cells.
    Gastroenterology. 2008;134:1494-506.
    PubMed     Related articles    Abstract available


  16. SALAS JT , Banales JM, Sarvide S, Recalde S, et al
    Ae2a,b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis.
    Gastroenterology. 2008;134:1482-93.
    PubMed     Related articles    Abstract available


  17. SANYAL AJ , Boyer T, Garcia-Tsao G, Regenstein F, et al
    A randomized, prospective, double-blind, placebo-controlled trial of terlipressin for type 1 hepatorenal syndrome.
    Gastroenterology. 2008;134:1360-8.
    PubMed     Related articles    Abstract available


  18. MARTIN-LLAHI M , Pepin MN, Guevara M, Diaz F, et al
    Terlipressin and albumin vs albumin in patients with cirrhosis and hepatorenal syndrome: a randomized study.
    Gastroenterology. 2008;134:1352-9.
    PubMed     Related articles    Abstract available


  19. IOANNOU GN , Perkins JD, Carithers RL Jr
    Liver transplantation for hepatocellular carcinoma: impact of the MELD allocation system and predictors of survival.
    Gastroenterology. 2008;134:1342-51.
    PubMed     Related articles    Abstract available


  20. BROWN RS JR
    Live donors in liver transplantation.
    Gastroenterology. 2008;134:1802-13.
    PubMed     Related articles    Abstract available


  21. ROSEN HR
    Transplantation immunology: what the clinician needs to know for immunotherapy.
    Gastroenterology. 2008;134:1789-801.
    PubMed     Related articles    Abstract available


  22. O'LEARY JG , Lepe R, Davis GL
    Indications for liver transplantation.
    Gastroenterology. 2008;134:1764-76.
    PubMed     Related articles    Abstract available


  23. LEONIS MA , Balistreri WF
    Evaluation and management of end-stage liver disease in children.
    Gastroenterology. 2008;134:1741-51.
    PubMed     Related articles    Abstract available


  24. O'BRIEN A , Williams R
    Nutrition in end-stage liver disease: principles and practice.
    Gastroenterology. 2008;134:1729-40.
    PubMed     Related articles   


  25. MANNING DS , Afdhal NH
    Diagnosis and quantitation of fibrosis.
    Gastroenterology. 2008;134:1670-81.
    PubMed     Related articles    Abstract available


  26. MALHI H , Gores GJ
    Cellular and molecular mechanisms of liver injury.
    Gastroenterology. 2008;134:1641-54.
    PubMed     Related articles    Abstract available


  27. BACON BR , Chang KM, Wells RG
    End-stage liver disease in 2008: finally a glass half full.
    Gastroenterology. 2008;134:1639-40.
    PubMed     Related articles   


  28. JUNG Y , Brown KD, Witek RP, Omenetti A, et al
    Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans.
    Gastroenterology. 2008;134:1532-43.
    PubMed     Related articles    Abstract available


  29. TANG SJ , Jazrawi SF
    Electronic clinical challenges and images in GI. ERCP in biliary fascioliasis (with video).
    Gastroenterology. 2008;134:e7-8.
    PubMed     Related articles   


    April 2008
  30. WONG QW , Lung RR, Law PT, Lai PB, et al
    MicroRNA-223 Is Commonly Repressed in Hepatocellular Carcinoma and Potentiates Expression of Stathmin1.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  31. RATZIU V , Giral P, Jacqueminet S, Charlotte F, et al
    Rosiglitazone for Nonalcoholic Steatohepatitis: One-Year Results of the Randomized Placebo-Controlled Fatty Liver Improvement With Rosiglitazone Therapy (FLIRT) Trial.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  32. CHEN CL , Yang HI, Yang WS, Liu CJ, et al
    Metabolic Factors and Risk of Hepatocellular Carcinoma by Chronic Hepatitis B/C Infection: A Follow-up Study in Taiwan.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  33. NIEHOF M , Borlak J
    EPS15R, TASP1, and PRPF3 are novel disease candidate genes targeted by HNF4alpha splice variants in hepatocellular carcinomas.
    Gastroenterology. 2008;134:1191-202.
    PubMed     Related articles    Abstract available


  34. INAGAKI Y , Higashi K, Kushida M, Hong YY, et al
    Hepatocyte growth factor suppresses profibrogenic signal transduction via nuclear export of Smad3 with galectin-7.
    Gastroenterology. 2008;134:1180-90.
    PubMed     Related articles    Abstract available


  35. HUBBARD AL , Braiterman LT
    Could ATP7B export Cu(I) at the tight junctions and the apical membrane?
    Gastroenterology. 2008;134:1255-7.
    PubMed     Related articles   


  36. HERNANDEZ S , Tsuchiya Y, Garcia-Ruiz JP, Lalioti V, et al
    ATP7B copper-regulated traffic and association with the tight junctions: copper excretion into the bile.
    Gastroenterology. 2008;134:1215-23.
    PubMed     Related articles    Abstract available


  37. STRAUTNIEKS SS , Byrne JA, Pawlikowska L, Cebecauerova D, et al
    Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families.
    Gastroenterology. 2008;134:1203-14.
    PubMed     Related articles    Abstract available


  38. STRNAD P , Tao GZ, Zhou Q, Harada M, et al
    Keratin mutation predisposes to mouse liver fibrosis and unmasks differential effects of the carbon tetrachloride and thioacetamide models.
    Gastroenterology. 2008;134:1169-79.
    PubMed     Related articles    Abstract available


  39. LAMLE J , Marhenke S, Borlak J, von Wasielewski R, et al
    Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injury.
    Gastroenterology. 2008;134:1159-68.
    PubMed     Related articles    Abstract available


  40. HORIGUCHI N , Wang L, Mukhopadhyay P, Park O, et al
    Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury.
    Gastroenterology. 2008;134:1148-58.
    PubMed     Related articles    Abstract available


  41. FRIEDRICH-RUST M , Ong MF, Martens S, Sarrazin C, et al
    Performance of transient elastography for the staging of liver fibrosis: a meta-analysis.
    Gastroenterology. 2008;134:960-74.
    PubMed     Related articles    Abstract available


    March 2008
  42. MAZZOCCA A , Liotta F, Carloni V
    Tetraspanin CD81-Regulated Cell Motility Plays a Critical Role in Intrahepatic Metastasis of Hepatocellular Carcinoma.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  43. KOTRONEN A , Juurinen L, Tiikkainen M, Vehkavaara S, et al
    Increased Liver Fat, Impaired Insulin Clearance, and Hepatic and Adipose Tissue Insulin Resistance in Type 2 Diabetes.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  44. HOECHST B , Ormandy LA, Ballmaier M, Lehner F, et al
    A New Population of Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Induces CD4(+)CD25(+)Foxp3(+) T Cells.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  45. HIRAMOTO T , Chida Y, Sonoda J, Yoshihara K, et al
    The Hepatic Vagus Nerve Attenuates Fas-Induced Apoptosis in the Mouse Liver via alpha7 Nicotinic Acetylcholine Receptor.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  46. FARIA LC , Gigou M, Roque-Afonso AM, Sebagh M, et al
    Hepatocellular Carcinoma Is Associated With an Increased Risk of Hepatitis B Virus Recurrence After Liver Transplantation.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  47. FELD JJ , Hussain N, Wright EC, Kleiner DE, et al
    Hepatic Involvement and Portal Hypertension Predict Mortality in Chronic Granulomatous Disease.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  48. FOX IJ , Strom SC
    To be or not to be: generation of hepatocytes from cells outside the liver.
    Gastroenterology. 2008;134:878-81.
    PubMed     Related articles   


  49. LECHEL A , Rudolph KL
    Rho GTPase and Wnt Signaling Pathways in Hepatocarcinogenesis.
    Gastroenterology. 2008;134:875-8.
    PubMed     Related articles   


  50. HE N , Park K, Zhang Y, Huang J, et al
    Epigenetic inhibition of nuclear receptor small heterodimer partner is associated with and regulates hepatocellular carcinoma growth.
    Gastroenterology. 2008;134:793-802.
    PubMed     Related articles    Abstract available


  51. VAN HENGEL J , D'Hooge P, Hooghe B, Wu X, et al
    Continuous cell injury promotes hepatic tumorigenesis in cdc42-deficient mouse liver.
    Gastroenterology. 2008;134:781-92.
    PubMed     Related articles    Abstract available


  52. EL-SERAG HB , White DL
    Genetic association studies: from "searching under the lamppost" to "fishing in the pond".
    Gastroenterology. 2008;134:662-4.
    PubMed     Related articles   


  53. KOORNSTRA JJ , Kleibeuker JH
    Electronic clinical challenges and images in GI. Biliocutaneous fistula secondary to pancreatic cancer.
    Gastroenterology. 2008;134:e1-2.
    PubMed     Related articles   


    February 2008
  54. KIM WR , Kamath PS
    Hepatic vein pressure gradient >10 mm Hg: prognostic or reflective?
    Gastroenterology. 2008;134:641.
    PubMed     Related articles   


  55. ZHOU J , Febbraio M, Wada T, Zhai Y, et al
    Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis.
    Gastroenterology. 2008;134:556-67.
    PubMed     Related articles    Abstract available


  56. FABBRINI E , Mohammed BS, Magkos F, Korenblat KM, et al
    Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease.
    Gastroenterology. 2008;134:424-31.
    PubMed     Related articles    Abstract available


  57. BACON BR
    Hepatology: small steps forward.
    Gastroenterology. 2008;134:381.
    PubMed     Related articles   


  58. LANG L
    New organ allocation criteria and decreased mortality on liver transplant waiting list.
    Gastroenterology. 2008;134:379-80.
    PubMed     Related articles   


  59. LANG L
    FDA approves sorafenib for patients with inoperable liver cancer.
    Gastroenterology. 2008;134:379.
    PubMed     Related articles   


  60. PURI P , Mirshahi F, Cheung O, Natarajan R, et al
    Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease.
    Gastroenterology. 2008;134:568-76.
    PubMed     Related articles    Abstract available


    January 2008
  61. MARI M , Colell A, Morales A, Caballero F, et al
    Mechanism of Mitochondrial Glutathione-Dependent Hepatocellular Susceptibility to TNF Despite NF-kappaB Activation.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  62. KORENBLAT KM , Fabbrini E, Mohammed BS, Klein S, et al
    Liver, Muscle, and Adipose Tissue Insulin Action Is Directly Related to Intrahepatic Triglyceride Content in Obese Subjects.
    Gastroenterology. 2008;.
    PubMed     Related articles    Abstract available


  63. VINCIGUERRA M , Veyrat-Durebex C, Moukil MA, Rubbia-Brandt L, et al
    PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism.
    Gastroenterology. 2008;134:268-80.
    PubMed     Related articles    Abstract available


  64. BOHNE F , Chmielewski M, Ebert G, Wiegmann K, et al
    T cells redirected against hepatitis B virus surface proteins eliminate infected hepatocytes.
    Gastroenterology. 2008;134:239-47.
    PubMed     Related articles    Abstract available


  65. NISHINA S , Hino K, Korenaga M, Vecchi C, et al
    Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription.
    Gastroenterology. 2008;134:226-38.
    PubMed     Related articles    Abstract available


  66. STADLBAUER VP , Wright GA, Banaji M, Mukhopadhya A, et al
    Relationship between activation of the sympathetic nervous system and renal blood flow autoregulation in cirrhosis.
    Gastroenterology. 2008;134:111-9.
    PubMed     Related articles    Abstract available


  67. ROCKEY DC
    Noninvasive assessment of liver fibrosis and portal hypertension with transient elastography.
    Gastroenterology. 2008;134:8-14.
    PubMed     Related articles    Abstract available


  68. ARTEEL GE
    Silencing a killer among us: ethanol impairs immune surveillance of activated stellate cells by natural killer cells.
    Gastroenterology. 2008;134:351-3.
    PubMed     Related articles   


  69. JEONG WI , Park O, Gao B
    Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis.
    Gastroenterology. 2008;134:248-58.
    PubMed     Related articles    Abstract available


  70. BAUMEISTER SE , Volzke H, Marschall P, John U, et al
    Impact of fatty liver disease on health care utilization and costs in a general population: a 5-year observation.
    Gastroenterology. 2008;134:85-94.
    PubMed     Related articles    Abstract available


    December 2007
  71. CAMPARD D , Lysy PA, Najimi M, Sokal EM, et al
    Native Umbilical Cord Matrix Stem Cells Express Hepatic Markers and Differentiate Into Hepatocyte-like Cells.
    Gastroenterology. 2007;.
    PubMed     Related articles    Abstract available


  72. VIGANO M , Aghemo A, Iavarone M
    The role of hepatic venous pressure gradient in hepatitis C virus compensated cirrhosis.
    Gastroenterology. 2007;133:2076.
    PubMed     Related articles   


  73. SANCHO-BRU P , Bataller R, Fernandez-Varo G, Moreno M, et al
    Bradykinin attenuates hepatocellular damage and fibrosis in rats with chronic liver injury.
    Gastroenterology. 2007;133:2019-28.
    PubMed     Related articles    Abstract available


  74. THALHEIMER U , Bosch J, Burroughs AK
    How to prevent varices from bleeding: shades of grey--the case for nonselective beta blockers.
    Gastroenterology. 2007;133:2029-36.
    PubMed     Related articles   


  75. LASSMANN S , Tang L, Capanu M, Brabletz T, et al
    Predictive molecular markers for colorectal cancer patients with resected liver metastasis and adjuvant chemotherapy.
    Gastroenterology. 2007;133:1831-9.
    PubMed     Related articles    Abstract available


  76. FRASER A , Longnecker MP, Lawlor DA
    Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999-2004.
    Gastroenterology. 2007;133:1814-20.
    PubMed     Related articles    Abstract available


  77. BERG CL , Gillespie BW, Merion RM, Brown RS Jr, et al
    Improvement in survival associated with adult-to-adult living donor liver transplantation.
    Gastroenterology. 2007;133:1806-13.
    PubMed     Related articles    Abstract available


    November 2007
  78. SANCHEZ W , Kamath PS
    Managing septic shock in patients with cirrhosis: the role of adrenal insufficency.
    Gastroenterology. 2007;133:1733-4.
    PubMed     Related articles   


  79. ZHU H , Dong H, Eksioglu E, Hemming A, et al
    Hepatitis C virus triggers apoptosis of a newly developed hepatoma cell line through antiviral defense system.
    Gastroenterology. 2007;133:1649-59.
    PubMed     Related articles    Abstract available


  80. HU M , Kurobe M, Jeong YJ, Fuerer C, et al
    Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells.
    Gastroenterology. 2007;133:1579-91.
    PubMed     Related articles    Abstract available


  81. KATOH H , Ojima H, Kokubu A, Saito S, et al
    Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets.
    Gastroenterology. 2007;133:1475-86.
    PubMed     Related articles    Abstract available


  82. BERRY PA , Cross TJ, Orr DW
    Clinical challenges and images in GI. Pulmonary embolization of histoacryl "glue" causing hypoxia and cardiovascular instability.
    Gastroenterology. 2007;133:1413.
    PubMed     Related articles   


  83. SELARU FM , Cross R, Drachenberg C, Cross R, et al
    Electronic clinical challenges and images in GI. Fibrolamellar carcinoma.
    Gastroenterology. 2007;133:e1-3.
    PubMed     Related articles   


  84. LI T , Chiang JY
    A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene.
    Gastroenterology. 2007;133:1660-9.
    PubMed     Related articles    Abstract available


    October 2007
  85. NAHON P , Sutton A, Rufat P, Ziol M, et al
    Liver Iron, HFE Gene Mutations, and Hepatocellular Carcinoma Occurrence in Patients With Cirrhosis.
    Gastroenterology. 2007;.
    PubMed     Related articles    Abstract available


  86. YANG H , Ara AI, Magilnick N, Xia M, et al
    Expression Pattern, Regulation, and Functions of Methionine Adenosyltransferase 2beta Splicing Variants in Hepatoma Cells.
    Gastroenterology. 2007;.
    PubMed     Related articles    Abstract available


  87. DRESNER-POLLAK R , Gabet Y, Steimatzky A, Hamdani G, et al
    Human Parathyroid Hormone 1-34 Prevents Bone Loss in Experimental Biliary Cirrhosis in Rats.
    Gastroenterology. 2007;.
    PubMed     Related articles    Abstract available


  88. SHAN Y , Zheng J, Lambrecht RW, Bonkovsky HL, et al
    Reciprocal Effects of Micro-RNA-122 on Expression of Heme Oxygenase-1 and Hepatitis C Virus Genes in Human Hepatocytes.
    Gastroenterology. 2007;133:1166-74.
    PubMed     Related articles    Abstract available


  89. PROTZER U , Seyfried S, Quasdorff M, Sass G, et al
    Antiviral activity and hepatoprotection by heme oxygenase-1 in hepatitis B virus infection.
    Gastroenterology. 2007;133:1156-65.
    PubMed     Related articles    Abstract available


  90. DE BIE P , van de Sluis B, Burstein E, van de Berghe PV, et al
    Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B.
    Gastroenterology. 2007;133:1316-26.
    PubMed     Related articles    Abstract available


    September 2007
  91. WIEGARD C , Wolint P, Frenzel C, Cheruti U, et al
    Defective T Helper Response of Hepatocyte-Stimulated CD4 T Cells Impairs Antiviral CD8 Response and Viral Clearance.
    Gastroenterology. 2007;.
    PubMed     Related articles    Abstract available


  92. RUNYON BA
    A pill a day can improve survival in patients with advanced cirrhosis.
    Gastroenterology. 2007;133:1029-31.
    PubMed     Related articles   


  93. GRACIA-SANCHO J , Lavina B, Rodriguez-Vilarrupla A, Brandes RP, et al
    Evidence Against a Role for NADPH Oxidase Modulating Hepatic Vascular Tone in Cirrhosis.
    Gastroenterology. 2007;133:959-966.
    PubMed     Related articles    Abstract available


  94. VOLZ T , Lutgehetmann M, Wachtler P, Jacob A, et al
    Impaired Intrahepatic Hepatitis B Virus Productivity Contributes to Low Viremia in Most HBeAg-Negative Patients.
    Gastroenterology. 2007;133:843-52.
    PubMed     Related articles    Abstract available


  95. FERNANDEZ J , Navasa M, Planas R, Montoliu S, et al
    Primary prophylaxis of spontaneous bacterial peritonitis delays hepatorenal syndrome and improves survival in cirrhosis.
    Gastroenterology. 2007;133:818-24.
    PubMed     Related articles    Abstract available


  96. LANG L
    Study points to new biomarker for nonalcoholic steatohepatitis diagnosis in children with nonalcoholic Fatty liver disease.
    Gastroenterology. 2007;133:739.
    PubMed     Related articles   


  97. MAYHEW CN , Carter SL, Fox SR, Sexton CR, et al
    RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis.
    Gastroenterology. 2007;133:976-84.
    PubMed     Related articles    Abstract available


  98. SCHILLER D , Fugger R, Schofl R
    Clinical challenges and images in GI. Image 1.
    Gastroenterology. 2007;133:746.
    PubMed     Related articles   


    August 2007
  99. DATTA S , Banerjee A, Chandra PK, Chakravarty R, et al
    Pin1-HBx Interaction: A Step Toward Understanding the Significance of Hepatitis B Virus Genotypes in Hepatocarcinogenesis.
    Gastroenterology. 2007;133:727-8.
    PubMed     Related articles   


  100. ALBANO E
    Seek and hide phosphatidylserine: a new approach to prevent hepatic ischemia/reperfusion injury.
    Gastroenterology. 2007;133:713-6.
    PubMed     Related articles   


  101. MENG F , Henson R, Wehbe-Janek H, Ghoshal K, et al
    MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer.
    Gastroenterology. 2007;133:647-58.
    PubMed     Related articles    Abstract available


  102. TEOH NC , Ito Y, Field J, Bethea NW, et al
    Diannexin, a novel annexin v homodimer, provides prolonged protection against hepatic ischemia-reperfusion injury in mice.
    Gastroenterology. 2007;133:632-46.
    PubMed     Related articles    Abstract available


  103. NOCITO A , Dahm F, Jochum W, Jang JH, et al
    Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis.
    Gastroenterology. 2007;133:608-18.
    PubMed     Related articles    Abstract available


  104. VAN MIL SW , Milona A, Dixon PH, Mullenbach R, et al
    Functional Variants of the Central Bile Acid Sensor FXR Identified in Intrahepatic Cholestasis of Pregnancy.
    Gastroenterology. 2007;133:507-16.
    PubMed     Related articles    Abstract available


  105. GASTALDELLI A , Cusi K, Pettiti M, Hardies J, et al
    Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects.
    Gastroenterology. 2007;133:496-506.
    PubMed     Related articles    Abstract available


  106. YU L , Ioannou GN
    Survival of liver transplant recipients with hemochromatosis in the United States.
    Gastroenterology. 2007;133:489-95.
    PubMed     Related articles    Abstract available


  107. RIPOLL C , Groszmann R, Garcia-Tsao G, Grace N, et al
    Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis.
    Gastroenterology. 2007;133:481-8.
    PubMed     Related articles    Abstract available


    July 2007
  108. SHIVAKUMAR P , Sabla G, Mohanty S, McNeal M, et al
    Effector Role of Neonatal Hepatic CD8(+) Lymphocytes in Epithelial Injury and Autoimmunity in Experimental Biliary Atresia.
    Gastroenterology. 2007;133:268-277.
    PubMed     Related articles    Abstract available


  109. NAGATA J , Guerra MT, Shugrue CA, Gomes DA, et al
    Lipid rafts establish calcium waves in hepatocytes.
    Gastroenterology. 2007;133:256-67.
    PubMed     Related articles    Abstract available


  110. NAKAMURA T , Torimura T, Sakamoto M, Hashimoto O, et al
    Significance and Therapeutic Potential of Endothelial Progenitor Cell Transplantation in a Cirrhotic Liver Rat Model.
    Gastroenterology. 2007;133:91-107.
    PubMed     Related articles    Abstract available


  111. RICHARDSON MM , Jonsson JR, Powell EE, Brunt EM, et al
    Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction.
    Gastroenterology. 2007;133:80-90.
    PubMed     Related articles    Abstract available


  112. THEISE ND , Kuwahara R
    The tissue biology of ductular reactions in human chronic liver disease.
    Gastroenterology. 2007;133:350-2.
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    June 2007
  113. SALERNO F , Camma C, Enea M, Rossle M, et al
    Transjugular Intrahepatic Portosystemic Shunt for Refractory Ascites: A Meta-analysis of Individual Patient Data.
    Gastroenterology. 2007;.
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  114. CHIBA T , Zheng YW, Kita K, Yokosuka O, et al
    Enhanced Self-Renewal Capability in Hepatic Stem/Progenitor Cells Drives Cancer Initiation.
    Gastroenterology. 2007;.
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  115. SEGAT L , Milanese M, Crovella S
    Pin1 promoter polymorphisms in hepatocellular carcinoma patients.
    Gastroenterology. 2007;132:2618-9.
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  116. EL-SERAG HB , Rudolph KL
    Hepatocellular carcinoma: epidemiology and molecular carcinogenesis.
    Gastroenterology. 2007;132:2557-76.
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  117. BERAZA N , Ludde T, Assmus U, Roskams T, et al
    Hepatocyte-Specific IKKgamma/NEMO Expression Determines the Degree of Liver Injury.
    Gastroenterology. 2007;132:2504-17.
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  118. GEISLER F , Algul H, Paxian S, Schmid RM, et al
    Genetic Inactivation of RelA/p65 Sensitizes Adult Mouse Hepatocytes to TNF-induced Apoptosis In Vivo and In Vitro.
    Gastroenterology. 2007;132:2489-503.
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  119. FU J , Xu D, Liu Z, Shi M, et al
    Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients.
    Gastroenterology. 2007;132:2328-39.
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  120. SCHWABE RF , Brenner DA
    Nuclear factor-kappaB in the liver: friend or foe?
    Gastroenterology. 2007;132:2601-4.
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  121. MA S , Chan KW, Hu L, Lee TK, et al
    Identification and characterization of tumorigenic liver cancer stem/progenitor cells.
    Gastroenterology. 2007;132:2542-56.
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    May 2007
  122. CARVALHO FILHO RJ , Milani AN, Sampaio JP, Schiavon LL, et al
    Distinguishing nonalcoholic fatty liver disease from alcoholic liver disease: is ANI enough?
    Gastroenterology. 2007;132:2076-7.
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  123. DESMOULIERE A
    Hepatic stellate cells: the only cells involved in liver fibrogenesis? A dogma challenged.
    Gastroenterology. 2007;132:2059-62.
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  124. KIM KH , Shin HJ, Kim K, Choi HM, et al
    Hepatitis B Virus X Protein Induces Hepatic Steatosis Via Transcriptional Activation of SREBP1 and PPARgamma.
    Gastroenterology. 2007;132:1955-67.
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  125. IMAI Y , Varela GM, Jackson MB, Graham MJ, et al
    Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide.
    Gastroenterology. 2007;132:1947-54.
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  126. LARSSON SC , Wolk A
    Coffee consumption and risk of liver cancer: a meta-analysis.
    Gastroenterology. 2007;132:1740-5.
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  127. PAREKH S , Anania FA
    Abnormal lipid and glucose metabolism in obesity: implications for nonalcoholic fatty liver disease.
    Gastroenterology. 2007;132:2191-207.
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    April 2007
  128. O'LEARY JG , Friedman LS
    Predicting Surgical Risk in Patients With Cirrhosis: From Art to Science.
    Gastroenterology. 2007;132:1609-1611.
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  129. LECHEL A , Holstege H, Begus Y, Schienke A, et al
    Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease.
    Gastroenterology. 2007;132:1465-75.
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  130. FERENCI P , Czlonkowska A, Merle U, Ferenc S, et al
    Late-onset Wilson's disease.
    Gastroenterology. 2007;132:1294-8.
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  131. LIU B , Herve J, Bioulac-Sage P, Valogne Y, et al
    Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma.
    Gastroenterology. 2007;132:1495-503.
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  132. ADACHI M , Osawa Y, Uchinami H, Kitamura T, et al
    The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells.
    Gastroenterology. 2007;132:1434-46.
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    March 2007
  133. THALHEIMER U , Leandro G, Mela M, Patch D, et al
    Systematic review of HVPG measurement: statistics versus clinical applicability.
    Gastroenterology. 2007;132:1201-2.
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  134. PRITCHARD MT , McMullen MR, Stavitsky AB, Cohen JI, et al
    Differential contributions of C3, C5, and decay-accelerating factor to ethanol-induced fatty liver in mice.
    Gastroenterology. 2007;132:1117-26.
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  135. MASYUK TV , Masyuk AI, Torres VE, Harris PC, et al
    Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3',5'-cyclic monophosphate.
    Gastroenterology. 2007;132:1104-16.
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  136. OH SH , Witek RP, Bae SH, Zheng D, et al
    Bone marrow-derived hepatic oval cells differentiate into hepatocytes in 2-acetylaminofluorene/partial hepatectomy-induced liver regeneration.
    Gastroenterology. 2007;132:1077-87.
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  137. WAKABAYASHI H , Okano K, Suzuki Y
    Clinical challenges and images in GI. Image 2. Perforative peritonitis on sclerosing encapsulating peritonitis (abdominal cocoon) in a patient with alcoholic liver cirrhosis.
    Gastroenterology. 2007;132:854.
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    February 2007
  138. LANG L
    Risk of mortality and elevated serum aminotransferases.
    Gastroenterology. 2007;132:475-6.
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    January 2007
  139. FINE EJ , Lee DE, Hawkins M
    Sweet Clarity: Less Invasive Measures of Hepatic Glucose Metabolism.
    Gastroenterology. 2007;.
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  140. PIETRANGELO A
    The Penetrance of Hemochromatosis: Mice to the Rescue.
    Gastroenterology. 2007;.
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  141. PARK IY , Sohn BH, Yu E, Suh DJ, et al
    Aberrant Epigenetic Modifications in Hepatocarcinogenesis Induced by Hepatitis B Virus X Protein.
    Gastroenterology. 2007;.
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  142. TEH SH , Nagorney DM, Stevens SR, Offord KP, et al
    Risk Factors for Mortality After Surgery in Patients With Cirrhosis.
    Gastroenterology. 2007;.
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  143. AHIMA RS
    Insulin resistance: cause or consequence of nonalcoholic steatohepatitis?
    Gastroenterology. 2007;132:444-6.
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  144. WALKER WA , Sherman P, Cohen M, Barnard J, et al
    State of pediatric gastroenterology, hepatology, and nutrition: 2006 and beyond.
    Gastroenterology. 2007;132:434-6.
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  145. PANZITT K , Tschernatsch MM, Guelly C, Moustafa T, et al
    Characterization of HULC, a Novel Gene With Striking Up-Regulation in Hepatocellular Carcinoma, as Noncoding RNA.
    Gastroenterology. 2007;132:330-42.
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  146. NAGATA H , Nishitai R, Shirota C, Zhang JL, et al
    Prolonged survival of porcine hepatocytes in cynomolgus monkeys.
    Gastroenterology. 2007;132:321-9.
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  147. WALLACE DF , Summerville L, Subramaniam VN
    Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload.
    Gastroenterology. 2007;132:301-10.
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  148. OTA T , Takamura T, Kurita S, Matsuzawa N, et al
    Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis.
    Gastroenterology. 2007;132:282-93.
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  149. DALY AK , Aithal GP, Leathart JB, Swainsbury RA, et al
    Genetic Susceptibility to Diclofenac-Induced Hepatotoxicity: Contribution of UGT2B7, CYP2C8, and ABCC2 Genotypes.
    Gastroenterology. 2007;132:272-81.
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  150. LIU C , Aronow BJ, Jegga AG, Wang N, et al
    Novel Resequencing Chip Customized to Diagnose Mutations in Patients With Inherited Syndromes of Intrahepatic Cholestasis.
    Gastroenterology. 2007;132:119-126.
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  151. LANG L
    Keith Lindor is New Editor-In-Chief of Hepatology.
    Gastroenterology. 2007;132:6-7.
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  152. GUPTA S
    Hog heaven on the road to liver cell therapy.
    Gastroenterology. 2007;132:450-3.
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  153. ALVARO D , Mancino MG, Glaser S, Gaudio E, et al
    Proliferating cholangiocytes: a neuroendocrine compartment in the diseased liver.
    Gastroenterology. 2007;132:415-31.
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  154. SIEBLER J , Wirtz S, Weigmann B, Atreya I, et al
    IL-28A is a key regulator of T-cell-mediated liver injury via the T-box transcription factor T-bet.
    Gastroenterology. 2007;132:358-71.
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  155. ORLENT H , Selleslag D, Vandecasteele S, Jalal PK, et al
    Clinical challenges and images in GI. Fasciola hepatica infection and Von Hippel-Lindau disease type 1 with pancreatic and renal involvement.
    Gastroenterology. 2007;132:15-6.
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  156. EL-SERAG HB
    Translational research: the study of community effectiveness in digestive and liver disorders.
    Gastroenterology. 2007;132:8-10.
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    December 2006
  157. LALEMAN W , Van Landeghem L, Van der Elst I, Zeegers M, et al
    Nitroflurbiprofen, a Nitric Oxide-Releasing Cyclooxygenase Inhibitor, Improves Cirrhotic Portal Hypertension in Rats.
    Gastroenterology. 2006;.
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  158. COLMENERO J , Bataller R, Sancho-Bru P, Bellot P, et al
    Hepatic Expression of Candidate Genes in Patients With Alcoholic Hepatitis: Correlation With Disease Severity.
    Gastroenterology. 2006;.
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  159. LAINE F , Deugnier Y
    Increased Expression of Hepcidin in Obese Patients: Impact on Phenotypic Expression of Hemochromatosis and Pathophysiology of Dysmetabolic Iron Overload Syndrome.
    Gastroenterology. 2006;131:2028.
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  160. TALWALKAR JA
    Shall we bury the sword? Imaging of hepatic fibrosis.
    Gastroenterology. 2006;131:1669-71.
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  161. LANG L
    Hepatology a Dynamic Discipline Says President-elect of AASLD.
    Gastroenterology. 2006;131:1665-6.
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  162. LANG L
    Charles Lightdale Editor for GI & Hepatology News.
    Gastroenterology. 2006;131:1664-5.
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  163. KHAN N , Mahdavian M, Messersmith R
    Clinical challenges and images in GI. Image 1. Hepatic encephalopathy secondary to a spontaneous type 1 portosystemic shunt.
    Gastroenterology. 2006;131:1672.
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    November 2006
  164. HUANG Y , Feld JJ, Sapp RK, Nanda S, et al
    Defective Hepatic Response to Interferon and Activation of Suppressor of Cytokine Signaling 3 in Chronic Hepatitis C.
    Gastroenterology. 2006;.
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  165. GOUYA L , Muzeau F, Robreau AM, Letteron P, et al
    Genetic Study of Variation in Normal Mouse Iron Homeostasis Reveals Ceruloplasmin as an HFE-Hemochromatosis Modifier Gene.
    Gastroenterology. 2006;.
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  166. D'AMICO G , Garcia-Pagan JC, Luca A, Bosch J, et al
    Hepatic vein pressure gradient reduction and prevention of variceal bleeding in cirrhosis: a systematic review.
    Gastroenterology. 2006;131:1611-24.
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  167. SONG K , Hanash S
    Unraveling the complex proteome for biomarker discovery in gastrointestinal and liver diseases.
    Gastroenterology. 2006;131:1375-8.
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    October 2006
  168. LANG L
    AGA Institute Appoints New Editor of Clinical Gastroenterology and Hepatology.
    Gastroenterology. 2006;.
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  169. BACON BR
    Hepatology: Where Do We Go From Here?
    Gastroenterology. 2006;.
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  170. THORGEIRSSON SS
    Genomic decoding of hepatocellular carcinoma.
    Gastroenterology. 2006;131:1344-6.
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  171. POON TC , Wong N, Lai PB, Rattray M, et al
    A Tumor Progression Model for Hepatocellular Carcinoma: Bioinformatic Analysis of Genomic Data.
    Gastroenterology. 2006;131:1262-1270.
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  172. CENI E , Crabb DW, Foschi M, Mello T, et al
    Acetaldehyde Inhibits PPARgamma via H(2)O(2)-Mediated c-Abl Activation in Human Hepatic Stellate Cells.
    Gastroenterology. 2006;131:1235-52.
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  173. LEE HC , Tian B, Sedivy JM, Wands JR, et al
    Loss of raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells.
    Gastroenterology. 2006;131:1208-17.
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  174. DUNN W , Angulo P, Sanderson S, Jamil LH, et al
    Utility of a new model to diagnose an alcohol basis for steatohepatitis.
    Gastroenterology. 2006;131:1057-63.
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  175. FERNANDEZ J , Del Arbol LR, Gomez C, Durandez R, et al
    Norfloxacin vs Ceftriaxone in the Prophylaxis of Infections in Patients With Advanced Cirrhosis and Hemorrhage.
    Gastroenterology. 2006;131:1049-56.
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  176. HOLUBEK WJ , Nelson LS
    Acetaminophen protein adducts: is acetaminophen to blame?
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  177. CHAN DW , Chan CY, Yam JW, Ching YP, et al
    Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer.
    Gastroenterology. 2006;131:1218-27.
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  178. MARCELLO T , Grakoui A, Barba-Spaeth G, Machlin ES, et al
    Interferons alpha and lambda Inhibit Hepatitis C Virus Replication With Distinct Signal Transduction and Gene Regulation Kinetics.
    Gastroenterology. 2006;.
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    September 2006
  179. LLOVET JM , Chen Y, Wurmbach E, Roayaie S, et al
    A Molecular Signature to Discriminate Dysplastic Nodules From Early Hepatocellular Carcinoma in HCV Cirrhosis.
    Gastroenterology. 2006;.
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  180. SOLAYMANI-DODARAN MA , Card TI, Aithal GU, West JO, et al
    Fracture Risk in People With Primary Biliary Cirrhosis: A Population-Based Cohort Study.
    Gastroenterology. 2006;.
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  181. KONIARIS LG , Perez EA, Livingstone AS
    DSRS versus TIPS for variceal bleeding: Lessons from late follow-up of 507 DSRS patients.
    Gastroenterology. 2006;131:978.
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  182. TILG H , Hotamisligil GS
    Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance.
    Gastroenterology. 2006;131:934-45.
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  183. BEKRI S , Gual P, Anty R, Luciani N, et al
    Increased adipose tissue expression of hepcidin in severe obesity is independent from diabetes and NASH.
    Gastroenterology. 2006;131:788-96.
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    August 2006
  184. AMIGO LU , Castro JU, Miquel JU, Zanlungo SI, et al
    Inactivation of Hepatic Microsomal Triglyceride Transfer Protein Protects Mice From Diet-induced Gallstones.
    Gastroenterology. 2006;.
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