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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Liver Diseases

Free Subscription Articles published in Cancer Res Retrieve available abstracts of 72 articles: HTML format

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August 2008
1. CHIANG DY , Villanueva A, Hoshida Y, Peix J, et al
   Focal gains of VEGFA and molecular classification of hepatocellular carcinoma.
   Cancer Res. 2008;68:6779-88.
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2. GHO JW , Ip WK, Chan KY, Law PT, et al
   Re-expression of transcription factor ATF5 in hepatocellular carcinoma induces G2-M arrest.
   Cancer Res. 2008;68:6743-51.
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3. CHEN KF , Yeh PY, Yeh KH, Lu YS, et al
   Down-regulation of phospho-Akt is a major molecular determinant of bortezomib-induced apoptosis in hepatocellular carcinoma cells.
   Cancer Res. 2008;68:6698-707.
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   July 2008
4. LEE JM , Wong CM, Ng IO
   Hepatitis B virus-associated multistep hepatocarcinogenesis: a stepwise increase in allelic alterations.
   Cancer Res. 2008;68:5988-96.
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5. HE X , Zhu Z, Johnson C, Stoops J, et al
   PIK3IP1, a negative regulator of PI3K, suppresses the development of hepatocellular carcinoma.
   Cancer Res. 2008;68:5591-8.
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6. SHASHKOVA EV , Doronin K, Senac JS, Barry MA, et al
   Macrophage depletion combined with anticoagulant therapy increases therapeutic window of systemic treatment with oncolytic adenovirus.
   Cancer Res. 2008;68:5896-904.
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7. BASU A , Contreras AG, Datta D, Flynn E, et al
   Overexpression of vascular endothelial growth factor and the development of post-transplantation cancer.
   Cancer Res. 2008;68:5689-98.
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8. MONTERO J , Morales A, Llacuna L, Lluis JM, et al
   Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma.
   Cancer Res. 2008;68:5246-56.
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9. DATTA J , Kutay H, Nasser MW, Nuovo GJ, et al
   Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis.
   Cancer Res. 2008;68:5049-58.
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10. HUANG G , Eisenberg R, Yan M, Monti S, et al
    15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3beta and a tumor suppressor in lung cancer.
    Cancer Res. 2008;68:5040-8.
    PubMed     Related articles    Abstract available
    
    
    June 2008
11. CRUZ-MUNOZ W , Man S, Xu P, Kerbel RS, et al
    Development of a preclinical model of spontaneous human melanoma central nervous system metastasis.
    Cancer Res. 2008;68:4500-5.
    PubMed     Related articles    Abstract available
    
    
    
12. CALVISI DF , Pinna F, Meloni F, Ladu S, et al
    Dual-specificity phosphatase 1 ubiquitination in extracellular signal-regulated kinase-mediated control of growth in human hepatocellular carcinoma.
    Cancer Res. 2008;68:4192-200.
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13. ZHAO J , Chen J, Lu B, Dong L, et al
    TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma.
    Cancer Res. 2008;68:4133-41.
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14. YANG W , Yan HX, Chen L, Liu Q, et al
    Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells.
    Cancer Res. 2008;68:4287-95.
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15. LEE DC , Kang YK, Kim WH, Jang YJ, et al
    Functional and clinical evidence for NDRG2 as a candidate suppressor of liver cancer metastasis.
    Cancer Res. 2008;68:4210-20.
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    May 2008
16. ANZO M , Cobb LJ, Hwang DL, Mehta H, et al
    Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression.
    Cancer Res. 2008;68:3342-9.
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    April 2008
17. ACEVEDO LG , Bieda M, Green R, Farnham PJ, et al
    Analysis of the mechanisms mediating tumor-specific changes in gene expression in human liver tumors.
    Cancer Res. 2008;68:2641-51.
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18. FUCHS BC , Fujii T, Dorfman JD, Goodwin JM, et al
    Epithelial-to-mesenchymal transition and integrin-linked kinase mediate sensitivity to epidermal growth factor receptor inhibition in human hepatoma cells.
    Cancer Res. 2008;68:2391-9.
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    March 2008
19. CHEN RN , Huang YH, Yeh CT, Liao CH, et al
    Thyroid hormone receptors suppress pituitary tumor transforming gene 1 activity in hepatoma.
    Cancer Res. 2008;68:1697-706.
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20. WU YF , Fu SL, Kao CH, Yang CW, et al
    Chemopreventive effect of silymarin on liver pathology in HBV X protein transgenic mice.
    Cancer Res. 2008;68:2033-42.
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21. YAMASHITA T , Forgues M, Wang W, Kim JW, et al
    EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma.
    Cancer Res. 2008;68:1451-61.
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    February 2008
22. HUNG JH , Lu YS, Wang YC, Ma YH, et al
    FTY720 induces apoptosis in hepatocellular carcinoma cells through activation of protein kinase C delta signaling.
    Cancer Res. 2008;68:1204-12.
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    January 2008
23. CHEN YW , Paliwal S, Draheim K, Grossman SR, et al
    p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein.
    Cancer Res. 2008;68:476-82.
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24. SCHAFER G , Wissmann C, Hertel J, Lunyak V, et al
    Regulation of vascular endothelial growth factor D by orphan receptors hepatocyte nuclear factor-4 alpha and chicken ovalbumin upstream promoter transcription factors 1 and 2.
    Cancer Res. 2008;68:457-66.
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25. SHEN Z , Yang ZF, Gao Y, Li JC, et al
    The kringle 1 domain of hepatocyte growth factor has antiangiogenic and antitumor cell effects on hepatocellular carcinoma.
    Cancer Res. 2008;68:404-14.
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26. SPADERNA S , Schmalhofer O, Wahlbuhl M, Dimmler A, et al
    The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer.
    Cancer Res. 2008;68:537-44.
    PubMed     Related articles    Abstract available
    
    
    December 2007
27. ROGERS AB , Theve EJ, Feng Y, Fry RC, et al
    Hepatocellular carcinoma associated with liver-gender disruption in male mice.
    Cancer Res. 2007;67:11536-46.
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28. KANG JS , Wanibuchi H, Morimura K, Gonzalez FJ, et al
    Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo.
    Cancer Res. 2007;67:11141-6.
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    November 2007
29. YAMASHITA T , Budhu A, Forgues M, Wang XW, et al
    Activation of Hepatic Stem Cell Marker EpCAM by Wnt {beta}-Catenin Signaling in Hepatocellular Carcinoma.
    Cancer Res. 2007;67:10831-10839.
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30. MATSUSHITA A , Gotze T, Korc M
    Hepatocyte Growth Factor Mediated Cell Invasion in Pancreatic Cancer Cells Is Dependent on Neuropilin-1.
    Cancer Res. 2007;67:10309-10316.
    PubMed     Related articles    Abstract available
    
    
    October 2007
31. YOSHIMURA K , Laird LS, Chia CY, Meckel KF, et al
    Live Attenuated Listeria Monocytogenes Effectively Treats Hepatic Colorectal Cancer Metastases and Is Strongly Enhanced by Depletion of Regulatory T Cells.
    Cancer Res. 2007;67:10058-10066.
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32. TAKAMI T , Kaposi-Novak P, Uchida K, Gomez-Quiroz LE, et al
    Loss of Hepatocyte Growth Factor/c-Met Signaling Pathway Accelerates Early Stages of N-nitrosodiethylamine Induced Hepatocarcinogenesis.
    Cancer Res. 2007;67:9844-51.
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33. TANG ZQ , Han LY, Lin HH, Cui J, et al
    Derivation of stable microarray cancer-differentiating signatures using consensus scoring of multiple random sampling and gene-ranking consistency evaluation.
    Cancer Res. 2007;67:9996-10003.
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34. EHATA S , Hanyu A, Hayashi M, Aburatani H, et al
    Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1.
    Cancer Res. 2007;67:9694-703.
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    September 2007
35. KOPITZ C , Gerg M, Bandapalli OR, Ister D, et al
    Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling.
    Cancer Res. 2007;67:8615-23.
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36. ARENA S , Isella C, Martini M, de Marco A, et al
    Knock-in of oncogenic Kras does not transform mouse somatic cells but triggers a transcriptional response that classifies human cancers.
    Cancer Res. 2007;67:8468-76.
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    August 2007
37. CHEN YW , Klimstra DS, Mongeau ME, Tatem JL, et al
    Loss of p53 and Ink4a/Arf Cooperate in a Cell Autonomous Fashion to Induce Metastasis of Hepatocellular Carcinoma Cells.
    Cancer Res. 2007;67:7589-96.
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38. JOHNSON CD , Esquela-Kerscher A, Stefani G, Byrom M, et al
    The let-7 microRNA represses cell proliferation pathways in human cells.
    Cancer Res. 2007;67:7713-22.
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39. GAVERT N , Sheffer M, Raveh S, Spaderna S, et al
    Expression of L1-CAM and ADAM10 in Human Colon Cancer Cells Induces Metastasis.
    Cancer Res. 2007;67:7703-12.
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40. CHANG MY , Boulden J, Katz JB, Wang L, et al
    Bin1 Ablation Increases Susceptibility to Cancer during Aging, Particularly Lung Cancer.
    Cancer Res. 2007;67:7605-12.
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41. LLUIS JM , Buricchi F, Chiarugi P, Morales A, et al
    Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-{kappa}B via c-SRC and oxidant-dependent cell death.
    Cancer Res. 2007;67:7368-77.
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    July 2007
42. GRAMANTIERI L , Ferracin M, Fornari F, Veronese A, et al
    Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma.
    Cancer Res. 2007;67:6092-9.
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43. WU TC
    The role of vascular cell adhesion molecule-1 in tumor immune evasion.
    Cancer Res. 2007;67:6003-6.
    PubMed     Related articles    Abstract available
    
    
    June 2007
44. LI HJ , Everts M, Pereboeva L, Komarova S, et al
    Adenovirus Tumor Targeting and Hepatic Untargeting by a Coxsackie/Adenovirus Receptor Ectodomain Anti-Carcinoembryonic Antigen Bispecific Adapter.
    Cancer Res. 2007;67:5354-5361.
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45. TRAPP C , Schwarz M, Epe B
    The Peroxisome Proliferator WY-14,643 Promotes Hepatocarcinogenesis Caused by Endogenously Generated Oxidative DNA Base Modifications in Repair-Deficient Csbm/m/Ogg1-/- Mice.
    Cancer Res. 2007;67:5156-61.
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46. SCHONTHAL AH
    Induction of apoptosis by celecoxib in cell culture: an uncertain role for cyclooxygenase-2.
    Cancer Res. 2007;67:5575-6.
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47. GONG X , Kole L, Iskander K, Jaiswal AK, et al
    NRH:quinone oxidoreductase 2 and NAD(P)H:quinone oxidoreductase 1 protect tumor suppressor p53 against 20s proteasomal degradation leading to stabilization and activation of p53.
    Cancer Res. 2007;67:5380-8.
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48. HIRAOKA K , Kimura T, Logg CR, Tai CK, et al
    Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model.
    Cancer Res. 2007;67:5345-53.
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49. CHENG J , Huo DH, Kuang DM, Yang J, et al
    Human macrophages promote the motility and invasiveness of osteopontin-knockdown tumor cells.
    Cancer Res. 2007;67:5141-7.
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    May 2007
50. NISHIDA N , Nishimura T, Nagasaka T, Ikai I, et al
    Extensive Methylation Is Associated with {beta}-Catenin Mutations in Hepatocellular Carcinoma: Evidence for Two Distinct Pathways of Human Hepatocarcinogenesis.
    Cancer Res. 2007;67:4586-4594.
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51. CHENG N , Chytil A, Shyr Y, Joly A, et al
    Enhanced Hepatocyte Growth Factor Signaling by Type II Transforming Growth Factor-{beta} Receptor Knockout Fibroblasts Promotes Mammary Tumorigenesis.
    Cancer Res. 2007;67:4869-77.
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52. FANTAPPIE O , Solazzo M, Lasagna N, Platini F, et al
    P-glycoprotein mediates celecoxib-induced apoptosis in multiple drug-resistant cell lines.
    Cancer Res. 2007;67:4915-23.
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53. WANG CC , Tsai MF, Dai TH, Hong TM, et al
    Synergistic activation of the tumor suppressor, HLJ1, by the transcription factors YY1 and activator protein 1.
    Cancer Res. 2007;67:4816-26.
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54. SAMARA RN , Laguinge LM, Jessup JM
    Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling.
    Cancer Res. 2007;67:4774-82.
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55. BOSCH JJ , Thompson JA, Srivastava MK, Iheagwara UK, et al
    MHC Class II-Transduced Tumor Cells Originating in the Immune-Privileged Eye Prime and Boost CD4+ T Lymphocytes that Cross-react with Primary and Metastatic Uveal Melanoma Cells.
    Cancer Res. 2007;67:4499-506.
    PubMed     Related articles    Abstract available
    
    
    
56. HUANG B , Zhao J, Shen S, Li H, et al
    Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling.
    Cancer Res. 2007;67:4346-52.
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57. PARENT R , Kolippakkam D, Booth G, Beretta L, et al
    Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth.
    Cancer Res. 2007;67:4337-45.
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58. HSIEH YH , Wu TT, Huang CY, Hsieh YS, et al
    p38 mitogen-activated protein kinase pathway is involved in protein kinase Calpha-regulated invasion in human hepatocellular carcinoma cells.
    Cancer Res. 2007;67:4320-7.
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    April 2007
59. CHING YP , Leong VY, Lee MF, Xu HT, et al
    P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation.
    Cancer Res. 2007;67:3601-8.
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60. KIM Y , Yoon JW, Xiao X, Dean NM, et al
    Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells.
    Cancer Res. 2007;67:3583-93.
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61. JIANG C , Pecha J, Hoshino I, Ankrapp D, et al
    TIP30 mutant derived from hepatocellular carcinoma specimens promotes growth of HepG2 cells through up-regulation of N-cadherin.
    Cancer Res. 2007;67:3574-82.
    PubMed     Related articles    Abstract available
    
    
    
62. ZIPIN-ROITMAN A , Meshel T, Sagi-Assif O, Shalmon B, et al
    CXCL10 promotes invasion-related properties in human colorectal carcinoma cells.
    Cancer Res. 2007;67:3396-405.
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63. MURATA K , Moriyama M
    Isoleucine, an essential amino Acid, prevents liver metastases of colon cancer by antiangiogenesis.
    Cancer Res. 2007;67:3263-8.
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    March 2007
64. DATTA J , Majumder S, Kutay H, Motiwala T, et al
    Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade.
    Cancer Res. 2007;67:2736-46.
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65. NICOUD IB , Jones CM, Pierce JM, Earl TM, et al
    Warm hepatic ischemia-reperfusion promotes growth of colorectal carcinoma micrometastases in mouse liver via matrix metalloproteinase-9 induction.
    Cancer Res. 2007;67:2720-8.
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66. JEANNOT E , Poussin K, Chiche L, Bacq Y, et al
    Association of CYP1B1 germ line mutations with hepatocyte nuclear factor 1alpha-mutated hepatocellular adenoma.
    Cancer Res. 2007;67:2611-6.
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67. SAXENA NK , Sharma D, Ding X, Lin S, et al
    Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells.
    Cancer Res. 2007;67:2497-507.
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68. ANDRIEUX LO , Fautrel A, Bessard A, Guillouzo A, et al
    GATA-1 is essential in EGF-mediated induction of nucleotide excision repair activity and ERCC1 expression through ERK2 in human hepatoma cells.
    Cancer Res. 2007;67:2114-23.
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    February 2007
69. HANSEN JE , Fischer LK, Chan G, Chang SS, et al
    Antibody-mediated p53 protein therapy prevents liver metastasis in vivo.
    Cancer Res. 2007;67:1769-74.
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70. RENARD CA , Labalette C, Armengol C, Cougot D, et al
    Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer.
    Cancer Res. 2007;67:901-10.
    PubMed     Related articles    Abstract available
    
    
    December 2006
71. SHI J , Liu Y, Zheng Y, Guo Y, et al
    Therapeutic expression of an anti-death receptor 5 single-chain fixed-variable region prevents tumor growth in mice.
    Cancer Res. 2006;66:11946-53.
    PubMed     Related articles    Abstract available
    
    
    
72. MARTINIVE P , Defresne F, Bouzin C, Saliez J, et al
    Preconditioning of the tumor vasculature and tumor cells by intermittent hypoxia: implications for anticancer therapies.
    Cancer Res. 2006;66:11736-44.
    PubMed     Related articles    Abstract available
    
    

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