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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Leukemia

Free Subscription Articles published in Proc Natl Acad Sci U S A Retrieve available abstracts of 43 articles: HTML format

Single Articles

May 2008
1. HELLMUTH K , Grosskopf S, Lum CT, Wurtele M, et al
   Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking.
   Proc Natl Acad Sci U S A. 2008;105:7275-80.
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2. PAULSSON K , Cazier JB, Macdougall F, Stevens J, et al
   Microdeletions are a general feature of adult and adolescent acute lymphoblastic leukemia: Unexpected similarities with pediatric disease.
   Proc Natl Acad Sci U S A. 2008;105:6708-13.
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   April 2008
3. YOSHIMURA FK , Luo X, Zhao X, Gerard HC, et al
   Up-regulation of a cellular protein at the translational level by a retrovirus.
   Proc Natl Acad Sci U S A. 2008;105:5543-8.
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4. O'HARE T , Eide CA, Tyner JW, Corbin AS, et al
   SGX393 inhibits the CML mutant Bcr-AblT315I and preempts in vitro resistance when combined with nilotinib or dasatinib.
   Proc Natl Acad Sci U S A. 2008;105:5507-12.
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   March 2008
5. CALIN GA , Cimmino A, Fabbri M, Ferracin M, et al
   MiR-15a and miR-16-1 cluster functions in human leukemia.
   Proc Natl Acad Sci U S A. 2008;.
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6. KIM C , Cheon M, Kang M, Chang I, et al
   A simple and exact Laplacian clustering of complex networking phenomena: application to gene expression profiles.
   Proc Natl Acad Sci U S A. 2008;105:4083-7.
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7. WANG L , Zhou GB, Liu P, Song JH, et al
   Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia.
   Proc Natl Acad Sci U S A. 2008;.
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8. GRIFFIOEN M , van der Meijden ED, Slager EH, Honders MW, et al
   Identification of phosphatidylinositol 4-kinase type II {beta} as HLA class II-restricted target in graft versus leukemia reactivity.
   Proc Natl Acad Sci U S A. 2008;.
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   February 2008
9. GARZON R , Garofalo M, Martelli MP, Briesewitz R, et al
   Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin.
   Proc Natl Acad Sci U S A. 2008;.
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10. FUKUDA T , Chen L, Endo T, Tang L, et al
    Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a.
    Proc Natl Acad Sci U S A. 2008;.
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11. MARCONDES AM , Mhyre AJ, Stirewalt DL, Kim SH, et al
    Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function.
    Proc Natl Acad Sci U S A. 2008;.
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12. ZHANG SJ , Ma LY, Huang QH, Li G, et al
    Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia.
    Proc Natl Acad Sci U S A. 2008;.
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    December 2007
13. MCLAUGHLIN J , Cheng D, Singer O, Lukacs RU, et al
    Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics.
    Proc Natl Acad Sci U S A. 2007;.
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14. MI S , Lu J, Sun M, Li Z, et al
    MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2007;.
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    November 2007
15. YANG F , Xian RR, Li Y, Polony TS, et al
    Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas.
    Proc Natl Acad Sci U S A. 2007;104:18952-7.
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16. PRADHAN A , Lambert QT, Reuther GW
    Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor.
    Proc Natl Acad Sci U S A. 2007;104:18502-7.
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17. GUIDEZ F , Parks S, Wong H, Jovanovic JV, et al
    RAR{alpha}-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia.
    Proc Natl Acad Sci U S A. 2007;.
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    September 2007
18. NAKANISHI H , Nakamura T, Canaani E, Croce CM, et al
    ALL1 fusion proteins induce deregulation of EphA7 and ERK phosphorylation in human acute leukemias.
    Proc Natl Acad Sci U S A. 2007;104:14442-7.
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    August 2007
19. BINSKY I , Haran M, Starlets D, Gore Y, et al
    IL-8 secreted in a macrophage migration-inhibitory factor- and CD74-dependent manner regulates B cell chronic lymphocytic leukemia survival.
    Proc Natl Acad Sci U S A. 2007;.
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    July 2007
20. RAE C , Langa S, Tucker SJ, MacEwan DJ, et al
    Elevated NF-kappaB responses and FLIP levels in leukemic but not normal lymphocytes: reduction by salicylate allows TNF-induced apoptosis.
    Proc Natl Acad Sci U S A. 2007;104:12790-5.
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21. HUYTON T , Zhang JG, Luo CS, Lou MZ, et al
    An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor.
    Proc Natl Acad Sci U S A. 2007;.
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22. HE W , Wang H, Hartmann LC, Cheng JX, et al
    In vivo quantitation of rare circulating tumor cells by multiphoton intravital flow cytometry.
    Proc Natl Acad Sci U S A. 2007;104:11760-5.
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23. EWENS WJ , Wilf HS
    Computing the distribution of the maximum in balls-and-boxes problems with application to clusters of disease cases.
    Proc Natl Acad Sci U S A. 2007;104:11189-91.
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    June 2007
24. NAKAMURA T , Canaani E, Croce CM
    Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing.
    Proc Natl Acad Sci U S A. 2007;104:10980-5.
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25. YANG J , Chai L, Liu F, Fink LM, et al
    Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells.
    Proc Natl Acad Sci U S A. 2007;104:10494-9.
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26. HOSEN N , Park CY, Tatsumi N, Oji Y, et al
    CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2007;.
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    May 2007
27. ZHANG M , Yao Z, Patel H, Garmestani K, et al
    Effective therapy of murine models of human leukemia and lymphoma with radiolabeled anti-CD30 antibody, HeFi-1.
    Proc Natl Acad Sci U S A. 2007;.
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    April 2007
28. TAMAYO P , Scanfeld D, Ebert BL, Gillette MA, et al
    Metagene projection for cross-platform, cross-species characterization of global transcriptional states.
    Proc Natl Acad Sci U S A. 2007;104:5959-64.
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29. RAFFEL GD , Mercher T, Shigematsu H, Williams IR, et al
    Ott1(Rbm15) has pleiotropic roles in hematopoietic development.
    Proc Natl Acad Sci U S A. 2007;104:6001-6.
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    March 2007
30. MIETHING C , Grundler R, Mugler C, Brero S, et al
    Retroviral insertional mutagenesis identifies RUNX genes involved in chronic myeloid leukemia disease persistence under imatinib treatment.
    Proc Natl Acad Sci U S A. 2007;104:4594-9.
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    February 2007
31. DERSE D , Hill SA, Princler G, Lloyd P, et al
    Resistance of human T cell leukemia virus type 1 to APOBEC3G restriction is mediated by elements in nucleocapsid.
    Proc Natl Acad Sci U S A. 2007;.
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    December 2006
32. WANG CL , Wang BB, Bartha G, Li L, et al
    Activation of an oncogenic microRNA cistron by provirus integration.
    Proc Natl Acad Sci U S A. 2006;103:18680-4.
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    November 2006
33. PALOMERO T , Lim WK, Odom DT, Sulis ML, et al
    NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
    Proc Natl Acad Sci U S A. 2006;103:18261-6.
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34. CHOI YH , Bernardi R, Pandolfi PP, Benveniste EN, et al
    The promyelocytic leukemia protein functions as a negative regulator of IFN-{gamma} signaling.
    Proc Natl Acad Sci U S A. 2006;.
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35. VILENCHIK MM , Knudson AG
    Radiation dose-rate effects, endogenous DNA damage, and signaling resonance.
    Proc Natl Acad Sci U S A. 2006;103:17874-9.
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    October 2006
36. HU Y , Swerdlow S, Duffy TM, Weinmann R, et al
    Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice.
    Proc Natl Acad Sci U S A. 2006;.
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37. BANSAL D , Scholl C, Frohling S, McDowell E, et al
    Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model.
    Proc Natl Acad Sci U S A. 2006;.
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38. GLASER S , Metcalf D, Wu L, Hart AH, et al
    Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia.
    Proc Natl Acad Sci U S A. 2006;.
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39. KAUFMANN SH
    Imatinib spells BAD news for Bcr/abl-positive leukemias.
    Proc Natl Acad Sci U S A. 2006;103:14651-2.
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40. KURODA J , Puthalakath H, Cragg MS, Kelly PN, et al
    Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.
    Proc Natl Acad Sci U S A. 2006;103:14907-12.
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41. SABAAWY HE , Azuma M, Embree LJ, Tsai HJ, et al
    TEL-AML1 transgenic zebrafish model of precursor B cell acute lymphoblastic leukemia.
    Proc Natl Acad Sci U S A. 2006;.
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    September 2006
42. MICHOR F , Iwasa Y, Nowak MA
    The age incidence of chronic myeloid leukemia can be explained by a one-mutation model.
    Proc Natl Acad Sci U S A. 2006;.
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    August 2006
43. SHANGGUAN D , Li Y, Tang Z, Cao ZC, et al
    Aptamers evolved from live cells as effective molecular probes for cancer study.
    Proc Natl Acad Sci U S A. 2006;103:11838-43.
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